KEGG   Panthera leo (lion): 122199609
Entry
122199609         CDS       T10741                                 
Symbol
CHKA
Name
(RefSeq) choline kinase alpha isoform X1
  KO
K14156  choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82]
Organism
plez  Panthera leo (lion)
Pathway
plez00564  Glycerophospholipid metabolism
plez01100  Metabolic pathways
plez05231  Choline metabolism in cancer
Module
plez_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC
plez_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE
Brite
KEGG Orthology (KO) [BR:plez00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    122199609 (CHKA)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    122199609 (CHKA)
Enzymes [BR:plez01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.32  choline kinase
     122199609 (CHKA)
    2.7.1.82  ethanolamine kinase
     122199609 (CHKA)
SSDB
Motif
Pfam: Choline_kinase APH EcKL Kdo PsiF_repeat Pkinase_fungal
Other DBs
NCBI-GeneID: 122199609
NCBI-ProteinID: XP_042760740
LinkDB
Position
D1:complement(110302939..110364644)
AA seq 488 aa
MKTKFCNGGEAEPSPLGLLLSCGGGSAAPAPGVGQQRDAASDLEPKQLGGPQPPLALPPP
PPPPLPLPPPPPPPPPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDQFHISVIRPSRR
PAVERIPVPGEDRSPPSRTIPLNHHQARGGLSNMLFQCSLPDTVATIGDEPRKVLLRLYG
AILKMRSCNKEGSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFI
PSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLNQVLRVKFAGEP
RVKQLHRLLRHNLPLELENLRSLLESTPSPVVFCHNDCQEGNILMLEGRENSEKQKLMLI
DFEYSSYNYRGFDIGNHFCEWMYDYNYEKYPFFRANVLKYPTKKQQLHFISNYLAAFQNE
FENLSNEEKCIIEEEMLLEVNRFALASHFFWGLWSIVQAKISSIEFGYMDYAQARFDAYF
DQKRKLGV
NT seq 1467 nt   +upstreamnt  +downstreamnt
atgaagaccaagttctgcaacgggggcgaggcggagccctcgccgctcgggctgctcctg
agctgcggcggcggcagcgcggccccggcgcccggcgtggggcagcagcgcgacgccgcc
agcgacctcgagcccaagcagctgggcggcccgcagccgccgctcgcgctgccgccgccg
ccgccgccgccgctgccgctgccgccgccgccgccgccgccgccgccgccggccgacgag
cagcccgagcctcggacgcggcgcagggcctatctgtggtgcaaggagttcctgcccggc
gcctggcggggccttcgcgaggaccagttccacatcagtgtcatcagaccttccagaaga
ccggctgttgaacggatcccggtgccaggcgaagacaggtctcctccgagcagaacaata
ccgttgaatcatcaccaagcgcgaggtggcctcagtaacatgctgttccagtgctcctta
cctgacaccgtggccaccattggtgacgagcctcggaaagtgctcctgcggctgtacggg
gcgattttaaagatgaggtcctgtaataaagagggatccgaacaagctcagaaagaaaat
gaatttcaaggggccgaggccatggttctggagagcgttatgtttgccattctcgcagag
aggtcgctgggacccaagctctacggcatcttcccccaaggccgcctggaacagtttatc
ccgagccggcgattagacactgaagaattaagtttgccagatatttctgcagaaatagct
gagaaaatggccacatttcatggtatgaaaatgccattcaataaggaaccaaaatggctt
tttggaacaatggaaaagtatctgaatcaagtcctgagggtcaagtttgccggggagccc
agagtgaagcagctccacagactcctccgccacaacctgcctctggaactggagaacctg
aggtcgctgctggaatccaccccttctccagttgtgttttgtcataacgactgtcaggaa
ggtaacatcttaatgctggaaggcagagagaattctgaaaagcagaaactgatgctcatc
gacttcgagtacagcagttataattacaggggatttgacattgggaatcatttctgtgag
tggatgtatgactataactatgaaaagtaccctttcttcagagccaacgtcctgaagtac
cccaccaagaaacagcagctccactttatttccaattacttggccgcattccaaaatgaa
tttgaaaacctcagtaatgaagaaaagtgcattatagaagaagagatgttgcttgaagtc
aataggtttgcccttgcgtcccatttcttctggggactttggtccatcgtacaggccaag
atttcttccattgaatttgggtacatggactatgcccaggcaaggttcgatgcctatttc
gaccagaagaggaagcttggggtgtga

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