Panthera leo (lion): 122200684
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Entry
122200684 CDS
T10741
Symbol
ABCC8
Name
(RefSeq) ATP-binding cassette sub-family C member 8 isoform X1
KO
K05032
ATP-binding cassette subfamily C (CFTR/MRP) member 8
Organism
plez Panthera leo (lion)
Pathway
plez02010
ABC transporters
plez04911
Insulin secretion
plez04930
Type II diabetes mellitus
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
122200684 (ABCC8)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
122200684 (ABCC8)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
122200684 (ABCC8)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
plez02000
]
122200684 (ABCC8)
Transporters [BR:
plez02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC8, 9 subgroups
122200684 (ABCC8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ABC_membrane
ABC_tran
SMC_N
AAA_21
ABC_ATPase
AAA_29
nSTAND1
ATPase
AAA_25
RsgA_GTPase
AAA_23
Beta-prop_IFT122_1st
TMD0_ABC
Motif
Other DBs
NCBI-GeneID:
122200684
NCBI-ProteinID:
XP_042762334
UniProt:
A0A8C8XJK9
LinkDB
All DBs
Position
D1:complement(73462541..73539307)
Genome browser
AA seq
1603 aa
AA seq
DB search
MPLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHI
HHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAVTS
VVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYG
MLLLVEVNVIRVRRYIFFKSPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTA
HKKPIDLRAIGKLPIAMRALTNYQRLCEAFDTQAQKDSQSTQGARAIWQALCRAFGRRLV
LSSTFRILADLLGFAGPLCIFGIVDHLGKENRVFQPKTQFLGVYFVSSQEFLANAYVLAV
LLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGDMTAGQICNL
VAIDTNQLMWFFFLCPNLWAMPVQIVVGVILLYYILGVSALIGAAVIILLAPVQYFVATK
LSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCTRVEMTRRKEMTSLRAFAVYT
SISIFMNTAIPIAAVLITFVGHVSFFKEADFSPSVAFASLSLFHILVTPLFLLSSVVRST
VKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQTNKYQAVEGGLPSLHSFQSCGPSPPP
DHSQPLKVVNRKHPAREDCRGFTAPLQRLVPSADGDADNYCVQIIGGFFTWTPDGIPTLS
NITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQKISGAVFWNSLPDETGEDPSPERETV
AYSDVRKRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGD
QTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLQD
DKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQEL
EKETVMERKATEPPQGLPRAMSSRDGLLQDEEEEEEEAAESEEEDNLSSVLHQRAKIPWR
ACAKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALTLSPAARNCSLSQECSL
DQTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLG
SILNRFSADCNTIDQHIPSTLECLSRSTLLCVSAVAVISYVTPVFLVALLPLAVVCYFIQ
KYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASL
FLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRDLSAGLVGLGLTYALMVSNYLNWMV
RNLADMEIQLGAVKRIHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLK
PVLKHVNALISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLR
SRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGG
ENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHR
VHTILSADLVIVLKRGAILEFDEPEKLLSRKDSVFASFVRADK
NT seq
4812 nt
NT seq
+upstream
nt +downstream
nt
atgcccttggccttctgcggcagcgagaaccactcggccgcctaccgggtggaccagggc
gtcctcaacaacggttgcttcgtggacgcgctcaacgtggtgcctcacgtcttcctgctc
ttcatcactttccccatcctcttcatcggatggggcagtcaaagctccaaggtacacatc
caccacagcacatggctccacttccctgggcacaacctgcgctggatcctgaccttcatg
ctgctcttcgtcctggtgtgtgaaatcgcagagggcatcctatctgatggggtgactgaa
tcccgccatctccacctgtacatgccagccgggatggcattcatggctgctgtcacctcc
gtggtctactatcacaacatcgagacctccaacttccccaagctgctgatagccctgcta
gtctactggaccctggccttcatcaccaagacgatcaagttcgtcaagttctatgaccat
gccatcggcttctcacagctgcgcttctgccttacggggctgttggtgatcctctacggg
atgctgctcctggtggaggtcaatgtcatcagggtgaggagatatatcttcttcaagtcg
ccaagggaggtaaagccccctgaggacctacaggacttgggggtgcgcttcctgcagccc
ttcgtgaatttgctatccaaaggcacctactggtggatgaatgctttcatcaagactgcc
cacaagaagcccattgatctccgagccattgggaagctgcccattgccatgagggccctc
accaactaccagcggctctgtgaggctttcgacacccaagcgcagaaggactcgcagagc
acgcagggtgcccgggccatctggcaggcactctgccgtgcctttgggagacgcctggtc
ctcagcagcactttccgtatactggctgacctgctgggcttcgccgggccgctgtgcatc
ttcgggattgtggaccaccttgggaaggaaaaccgcgtcttccagcccaagacgcagttt
ctcggggtttactttgtctcatcccaagagttccttgctaatgcctacgtcttggccgtg
cttctgttccttgccctcctactgcaaagaacatttctacaagcatcctactatgtcgcc
atcgaaactggaattaacttgagaggagcaatacagaccaagatttacaataaaattatg
cacctgtccacctccaacctgtccatgggggacatgacagctgggcagatctgcaacctg
gttgccattgacaccaaccagctcatgtggtttttcttcctgtgcccaaacctttgggcc
atgccagtacagatcgtcgtgggtgtgattctcctctactacatccttggagtcagtgcc
ttaattggggcagctgtcatcatcctactggcccccgtccagtactttgtggccaccaag
ctctcccaggcccagaggagcacactggagtattccaacgagaggctgaagcagaccaac
gagatgctccgtggcatcaagctgctcaagctgtacgcctgggagaacatcttctgcacg
cgtgtggagatgacccgcaggaaggagatgaccagcctcagagccttcgccgtctacacc
tccatttccattttcatgaacacggccatccccattgcagctgtcctcattaccttcgtg
ggccacgtcagcttcttcaaagaggccgacttctcgccctcagtggccttcgcctccctc
tcgctattccacatcctggtcacaccactgttcctcctgtccagcgtggtccggtcgaca
gtcaaagctctagtcagcgtgcaaaagctgagcgagttcctgtccagtgcagagatccgc
gaggagcagtgtgctccccgggagcctgcgccccagggccaaaccaacaagtaccaggca
gtggaggggggactcccttccctgcacagcttccagtcctgtgggccctcacctcctcct
gaccattcccagccccttaaggttgtgaaccgcaagcatccagcccgagaggactgtcgg
ggcttcacggccccactgcagaggctggttccgagtgcagatggggatgctgacaactac
tgtgtccagatcattggaggcttcttcacgtggactcctgatggaatccccacactgtcc
aacatcaccatccgcatcccacgaggccagctgaccatgatcgtggggcaggtgggctgt
ggcaagtcctcactcctcctagccaccctaggagagatgcagaagatttcaggggccgtc
ttctggaacagccttcctgatgagacgggagaggaccccagcccagagcgggagacggtg
gcctactcggatgtgaggaagagaggccccgtggcgtatgcttctcagaaaccatggctg
ctaaatgccactgtggaggagaatatcacctttgagagtcccttcaacaaacaacggtac
aaaatggtcatcgaagcctgctccctgcagccggacatcgacatcctgccccatggagac
cagactcagattggggaacggggcatcaacctatctggtggtcaacgccagcgaatcagt
gtggcccgagccctgtaccagcacaccaacgttgtcttcttggatgaccccttctcagct
ctggatgtccatctgagtgaccacctgatgcaggccgggatccttgagctgctccaggat
gacaagaggacagtggtcctagtgacccacaagctacagtacctgccacatgcagactgg
atcattgcgatgaaggatggcaccatccagagggagggcacgctcaaggacttccagagg
tctgagtgccagctctttgagcactggaagaccctcatgaaccggcaggaccaagagctg
gagaaggagactgtcatggagagaaaagccactgagccacctcagggtctgccccgggcc
atgtcctcaagagacggcctcctgcaagatgaggaagaggaggaagaggaggcagctgag
agtgaggaggaggacaacctgtcttcagtgcttcaccagcgtgccaagatcccgtggcga
gcctgtgccaagtatctgtcatccgccggcatcctgctcctgtcgctgctggtcttctcc
cagctgctcaagcacatggtcttggtggccattgactactggctggccaagtggaccgac
agtgccctgaccctgagcccagcagccaggaactgctccctcagccaggagtgctccctc
gaccagactgtctatgccatggtgttcacggtgctctgcagcctgggcattgtgctgtgc
cttgtcacatctgtcaccgtagaatggaccgggctgaaggtggccaaaaggttgcaccgc
agcctgctgaaccggatcatcctggctcccatgaggttttttgagaccacgccccttgga
agcatcctgaatagattttcagctgactgtaacaccattgaccagcacatcccatccacg
ctagagtgcctgagccgctccaccctgctctgtgtctcagccgtggctgtcatctcctat
gtcacgcctgtgttcctcgtggccctcttgcccctggccgtggtgtgctacttcatccag
aagtacttccgggtggcatccagggacctgcagcagctagatgacaccacccagctcccc
ctgctgtcccacttcgctgaaaccgtggaaggcctcaccaccatccgggccttcaggtat
gaggctaggttccagcagaagctccttgaatacacagactccaacaacattgcctccctc
ttcctcaccgctgccaacagatggctagaagtccgcatggagtacattggtgcatgtgtg
gtcctcatcgcagccgtgacctccatctccaactccctgcacagggacctctctgctggc
ctggtgggcctgggcctcacctatgccctaatggtctccaactacctcaactggatggtg
aggaacctagcagacatggagatccagctgggagctgtgaaacgcatccacgggctgctg
aaaaccgaagcggagagctacgagggactgctagcaccctcgctgatcccgaagaactgg
ccggaccaagggaagatccagatccagaacctgagtgtgcgctatgacagctccctgaag
ccagtgctgaagcatgtcaacgccctcatctccccaggacagaagattgggatctgtggc
cgcacaggcagcgggaagtcctccttctctcttgccttcttccgcatggtggacatgttc
gaagggcgtatcatcatcgacggcatcgacatcgccaaactgccgctgcacaccctgcgc
tcacgcctctctatcatcctgcaggaccccgtcctcttcagtggcaccatccgatttaac
ctggacccggagaagaagtgctctgacagcacgctgtgggaggccctggagatagcccag
ctgaagctggtggtgaaggcgctgccgggaggcctggatgccatcatcactgaaggtggg
gagaatttcagtcagggtcagaggcaactgttctgcctggctcgggccttcgtgcgaaag
accagcatcttcatcatggacgaagccacggcttccattgacatggccacggaaaacatc
ctccagaaggtggtgatgacggccttcgcagaccgcactgtggtcaccatcgcgcaccgt
gtgcacaccatcctgagcgcagacttggtgattgtcctgaaacgtggcgccatccttgag
ttcgacgagccagagaagctgctcagccggaaggacagcgtcttcgcctcgtttgtccgt
gcagacaagtga
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integrated database retrieval system
