Panthera leo (lion): 122201026
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Entry
122201026 CDS
T10741
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
plez Panthera leo (lion)
Pathway
plez04270
Vascular smooth muscle contraction
plez04360
Axon guidance
plez04611
Platelet activation
plez04625
C-type lectin receptor signaling pathway
plez04810
Regulation of actin cytoskeleton
plez05135
Yersinia infection
plez05152
Tuberculosis
plez05163
Human cytomegalovirus infection
plez05200
Pathways in cancer
plez05205
Proteoglycans in cancer
Brite
Membrane trafficking [BR:
plez04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
122201026 (ARHGEF12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
122201026
NCBI-ProteinID:
XP_042762816
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Position
D1:17709261..17857377
Genome browser
AA seq
1597 aa
AA seq
DB search
MQLLLNRIQVRENCSGSWFSIGSLGTSGILYQNLPGCCSQPLTQAAIVLGFPLKKPIRHG
SILNRESPTDKKQKVERSASHDFDPTDSSSKKTKSSSEESRSEIYGLVQRCVIIQKDDNG
FGLTVSGDNPVFVQSVKEGKAFFKTVLSLGSKQNGAAMRAGVQTGDRIIKVNGTLVTHSN
HLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVESSVIGHMSPIMTSPHSPGASGNME
RITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHI
PQLQEQLSKATGSAQDGAVVTSSRSLGDPPTVSEVEADPGDGLGRIDYSSGDASRPSSDS
AESPKSALKERIYLEENPEKSEVIQDTDTQSLIGSPSPRMAPHIIGAEDDDFGTEHEQIN
GQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRRVFLEFH
QFFLDRSAHLKVSVPDEISIDLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQK
RSMGLTLAESELTKLDAERDKDRVTLEKERACAEQIVAKIEEVLMTAQAVEEDKSSTMQY
VILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSILGPPRR
PSRHDNSAIGRAMELQKQRHPKHLSTPSSVSPEPQDSAKLRQSGLAGEGTDVGYLPANSM
SSGASGATLSQEGGKENDLGSKQVGETPASGDCMDGAPRTPNTIFDFPPPPLDQVQEEEW
EVERVPEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEI
KRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLN
EQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDS
RFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPMEREKVKKAADH
CRQILNYVNQAVKEAENKQRLEDYQRRLDTSNLKLSEYPNVEELRNLDLTKRKMIHEGPL
VWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLNTVL
VRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSAKPIPLPQ
SPPCEGDNDEEEPPKLKVEHHSISVPGLQSPDRDLGLESPLISSKPQSHSLGASGKSEVD
DLFVAERQFAKERHADGTLQEAGASYQIPIPDPHLPASEERWALDALRNLGLLKQLLVQQ
LGLAEKSTQEDWSRFPRYRTASSGVQTDSITQNSENSKACPPGEGQVSCRTESGDISTCY
SPRTSTESSAPRDSVVLAFQDSQASNILVMDHMIMTPEMPPAEPEGSLDESGEHFFDARE
AHSDDNPSEGDGVVKKEEDVNLRISGNYLILDGYDAVQESSTDEEVASSLPPPPTTGAPP
TDSAGQQQHSPQNAHSDGALSPFTPEFLVQQRWGAMEDSCFEIQSPPCCADSQSQIMEYI
RKIEADLEHLKKVEESYNILCQRLAGSALTDKHSDKS
NT seq
4794 nt
NT seq
+upstream
nt +downstream
nt
atgcagttattgcttaataggatacaagtaagagaaaactgctcaggaagctggttttca
atcggtagtctgggaacttccgggattctttaccagaatctccctggatgttgcagtcag
cccctgacgcaagcggccattgttttggggtttcccctcaaaaaacctataaggcatgga
agtattttgaaccgagagtcaccaacagataagaagcagaaagttgagcgcagtgcatca
catgattttgatcccacagatagctcctccaagaagacaaagtctagttcagaggagagt
agatccgagatatatggtcttgttcagcgttgtgtgatcatccagaaggatgacaatgga
tttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaaggcaag
gcattttttaaaacagtcttgtcacttgggagcaaacagaatggagcagccatgcgggct
ggagtacagacaggtgatcgaatcatcaaggtgaatggtacattggtgactcattcaaac
catttggaagtggtgaagctaatcaaatctggttcctatgtagctctcactgtgcaggga
cgcccacctgggtcgccccagattccacttgccgattctgaagtagagtcatcagtcatt
ggacatatgtctcccatcatgacatcccctcattcacctggagcatctgggaacatggag
agaattactagtcctgtgctcatgggggaggaaaacaatgtggttcataaccagaaagta
gaaattctgagaaaaatgttacagaaagaacaagaacggctgcagttattgcaggaagat
tacaaccgaacacctgcccaaagattgctaaaagagatccaagaggccaagaaacacatt
cctcagctgcaagagcagttatccaaagccacaggctctgctcaggatggagctgtagtt
acgtcctccaggtctttaggtgaccccccgacagtcagtgaggtagaagcagaccctggt
gacggactagggagaattgactacagcagcggagatgcttctcggcccagtagtgacagc
gcagaaagtcccaagagtgccctgaaagagaggatttatctagaggaaaacccagagaaa
agcgaagtgattcaggacactgacactcagtcactcatcgggagcccctctccccgaatg
gcacctcatattattggagcagaggatgatgattttggtactgaacatgaacagatcaat
gggcagtgcagctgtttccagagcattgaactgctaaaatctcgccctgctcacctggct
gttttcttacaccacgtagtttcacagtttgaccctgcaacgttgctctgttatctctat
tcagacctatataagcagaccaattccaaggagactcggcgtgtcttcctcgagtttcat
cagtttttcctggatcgatctgcacacctgaaagtttctgttcctgatgaaatatcaata
gatctagaaaaaagaagacctgagcttatacctgaggatctacaccgccactatattcaa
actatgcaggaaagagtccacccagaagttcagaggcacttggaagattttcggcagaaa
cgtagcatggggctgaccttggctgaaagcgagctgacaaaactcgatgcggagcgagac
aaggaccgggtaactttggagaaggaacgggcatgtgcggaacagattgttgccaaaatc
gaagaagtgttgatgactgctcaggctgtagaagaagataaaagttcaacaatgcagtat
gttatccttatgtacatgaagcatttgggagtaaaagtgaaagagcctcgaaatttggag
cacaagcgaggtcggattggattccttccaaaaatcaagcaaagtatgaagaaagatcga
gaaggcgaagaaaaagggaagcgcagaggattccccagcatcctgggacccccaaggaga
ccaagccgtcatgacaacagtgcaattggcagagctatggaactacagaagcagcggcac
cctaagcacttatccacaccctcttctgtgagtcctgagcctcaggactctgccaagttg
cgccagagtgggttagcaggtgaaggaacagacgttgggtacctgccagccaattccatg
tcctctggggcttcaggggccactctttcccaggaaggagggaaagagaatgatctggga
tcaaagcaagttggagaaacacctgcatctggagactgcatggatggcgcccctcgcact
cccaataccatcttcgatttcccacctcctcccttagaccaagtgcaggaggaggagtgg
gaagtggaaagggtgcctgaacatgggacaccaaagccctttcgaaaattcgacagcata
gcttttggagaaagtcaaagtgaggatgaacagtttgaaaatgacttagagacagatcca
cccaactggcaacagctcgttagtcgagaagtgttactgggactaaagccttgtgagatc
aaaagacaggaagtaattaatgaattgttctacactgaaagagctcatgttcgaacactg
aaggttcttgatcaagtgttctaccagcgagtatccagagaaggaattctgtcaccttca
gaactacggaaaattttttcaaacttggaagatattcttcaacttcacattggattgaat
gagcaaatgaaggctgttcgaaagaggaatgagacctcagttattgatcagattggggaa
gatttactgacctggttcagcggaccaggggaggagaagttgaaacacgctgctgccacc
ttttgcagtaaccaaccttttgccctggaaatgatcaagtctcgtcagaaaaaggattcc
cgatttcagacttttgtgcaagatgccgagagcaatccgctgtgtcgtcgtctgcagctg
aaggatatcattcctacccaaatgcagaggcttactaagtaccctcttctgttagataat
attgccaaatacacagaatggccaatggaaagggagaaggtgaagaaagctgcagatcac
tgtcgtcagatcttaaactatgtaaatcaggctgtcaaggaggcagaaaataagcagcgc
ctagaagactatcagcgtcgcctcgatacctccaatctgaagttgtcagagtacccaaat
gtggaagagctcaggaatttggatttaacaaaaaggaagatgattcacgaagggccactg
gtctggaaggtgaatcgggataaaactattgatctgtacacgttgctgctggaagacatt
cttgtattgttacaaaaacaggatgacagactggtgttacgatgtcatagtaagattctg
gcatccacagctgatagcaaacacacgtttagccctgtcattaagttgaatacagtgttg
gttcgacaagtggcaacagataacaaagctttgtttgtcatctccatgtcggacaatggg
gcccaaatttatgaactggtggcacagacagtttctgaaaagactgtctggcaggacctt
atctgccggatggccgcatcagtgaaggaacagtcggcgaagcccatcccactgccccag
tcaccaccttgcgaaggagacaacgatgaagaagaacctccaaaattaaaagtggagcat
catagcatttcagtccctggtctgcagagtccagacagagatttgggattagagtctccc
ttgatatcgtcaaaacctcagtctcattcactgggtgcctctgggaagtccgaggtagat
gatctgtttgtggctgagagacagtttgctaaggagcggcatgcagatgggactctgcag
gaagctggagcaagttaccaaatcccaatcccagacccgcacttgcctgcctcagaagaa
cggtgggccttggacgcactaaggaatttgggcttgttgaagcagttgcttgtacaacag
ctgggtttggctgagaagagcactcaggaagactggtcacgtttcccgagatacaggaca
gcgtcttccggggtgcagacagacagtataacccagaactctgaaaatagtaaggcctgt
cctcctggtgaaggacaggtgtcctgtagaactgaaagtggtgacatttccacttgttac
agtccacggacttcaactgaatcttctgctccacgagattcagtggtactggcattccaa
gatagccaggcaagtaacattttagtaatggaccacatgattatgaccccagagatgcct
cctgcagagccagaagggagtcttgatgagagtggagagcacttttttgatgcccgggaa
gcacatagtgatgataatccatcagaaggtgatggagtggttaagaaggaagaggatgtt
aatttgcgcatctcaggaaactatttgatccttgacggctacgatgcggtgcaggagagc
tccacggatgaggaggttgcttcctcactccccccaccgcccacgacaggcgcccccccc
acggactctgccggccagcagcagcattctccccagaacgcccattccgatggggcgctc
tcaccgttcaccccggaattcctggtccagcagcgctggggagctatggaggattcctgt
tttgagatccagagtcccccctgttgtgcagactcacaaagccagatcatggagtacatt
cgtaagatcgaggctgaccttgaacacttaaagaaggtggaggaaagttacaacattctt
tgccaaaggctggctggatcagccctcacagacaagcactcagataaaagttag
DBGET
integrated database retrieval system
