Panthera leo (lion): 122201421
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Entry
122201421 CDS
T10741
Symbol
GAB2
Name
(RefSeq) GRB2-associated-binding protein 2 isoform X1
KO
K08091
GRB2-associated-binding protein 2
Organism
plez Panthera leo (lion)
Pathway
plez04014
Ras signaling pathway
plez04071
Sphingolipid signaling pathway
plez04072
Phospholipase D signaling pathway
plez04380
Osteoclast differentiation
plez04664
Fc epsilon RI signaling pathway
plez04666
Fc gamma R-mediated phagocytosis
plez05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
122201421 (GAB2)
04072 Phospholipase D signaling pathway
122201421 (GAB2)
04071 Sphingolipid signaling pathway
122201421 (GAB2)
09150 Organismal Systems
09151 Immune system
04664 Fc epsilon RI signaling pathway
122201421 (GAB2)
04666 Fc gamma R-mediated phagocytosis
122201421 (GAB2)
09158 Development and regeneration
04380 Osteoclast differentiation
122201421 (GAB2)
09160 Human Diseases
09162 Cancer: specific types
05220 Chronic myeloid leukemia
122201421 (GAB2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:
plez04990
]
122201421 (GAB2)
Domain-containing proteins not elsewhere classified [BR:
plez04990
]
Pleckstrin homology (PH) domain-containing proteins
Grb-2 associated binder (Gab) family proteins
122201421 (GAB2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PH
PH_11
PH_2
PH_9
PH_3
PH_8
SOS1_NGEF_PH
Motif
Other DBs
NCBI-GeneID:
122201421
NCBI-ProteinID:
XP_042763217
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All DBs
Position
D1:53631411..53820672
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AA seq
678 aa
AA seq
DB search
MSGGGDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNDHSKKPLRI
INLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEEDMNKWVQSICQICGFNQ
AEESTDSLRNMSSASHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHM
QPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNG
VSGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKSSLTGSETDNEDIYTFKTPSN
TLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMAVATPGDSAIAPPPRPPKPSQ
AETPRWGSPQQRPPISESSRSVSAAATIPRRNTLPAMDSSRLHRASSCESYEYPQRGGES
AGRSAESMSDAVRSFLPGKTVVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIP
MSPGPHHFDALGYPSTALSLHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDE
LPFKSPVTKSWSRAVHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPIPS
GTSSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQSTM
QEWTDVRQSSEPSKGTKL
NT seq
2037 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcggcggcgacgtggtgtgcaccggctggctgaggaaatcgcctcccgagaag
aagttgaggcgctatgcctggaagaagcgatggtttatcctgcggagtggccggatgagt
ggtgacccagatgttctggaatactacaagaacgatcactctaagaagcccttgaggatc
atcaacctgaacttctgtgagcaggtggatgcaggcctgaccttcaacaagaaggagctg
caggatagttttgtgtttgacatcaagaccagtgaacgcaccttttatctggtggccgag
acggaggaggacatgaataagtgggtccagagcatctgccagatctgtggcttcaatcag
gctgaggagagcacagactccctgagaaacatgtcctctgccagtcacggcccccgctct
tctccagctgagctcagcagctccagtcagcaccttcttcgagaacgcaagtcctcagcc
ccatcgcactccagccagccaaccttgttcacctttgaaccccctgtgtccaaccacatg
cagcccaccttgtccaccagtgcgcctcaggagtatctctacttgcaccagtgcataagc
cggagagcggaaaatgcaaggagtgccagcttctctcagggcaccagggcctcgtttctc
atgaggagcgacacagctgtacagaaacttgcccagggcaatggacactgcgtcaatggg
gtcagcggtcaagtccatggcttctatagcctccccaagccaagccggcacaatacagaa
ttcagagacagtacctacgacctcccccggagtctggcctcccacggccacaccaagagc
agccttacgggctctgagaccgataatgaggacatatacaccttcaagacacccagcaac
actctatgtcgggagtttggggacctcctggtggacaatatggacgttccagccacccca
ctctcagcctaccagatccctaggacattcacgctggacaagaaccacaatgccatggca
gtggccactcctggggattcggccatagctcccccaccccggccccccaagccaagtcag
gcagaaacacctcgatggggcagtcctcagcagagacctccaatcagtgaaagcagcaga
tccgtctctgccgctgccaccatccccaggcgcaataccctcccggcgatggacagcagc
cggctccaccgagcttcttcctgtgaatcctacgagtacccccagcgaggaggagagagt
gcaggccggtctgccgagtccatgagtgatgcggtccgttctttcctgccagggaaaaca
gttgtaggccgatcagatagcaccaattctgaggacaactacgtgcccatgaatccaggt
tcctccaccctgctggccatggagcgagcaggtgataattcccagagtgtctacatcccc
atgagcccaggaccccatcactttgacgcgcttggctacccctcaacagccctttctctg
caccggggccccagccgagggagtgagatccagccaccccctgtcaaccgcaacctcaaa
cctgaccggaaagcaaagccaacaccacttgacctgagaaacaacactgtcatcgatgag
ctccccttcaagtcacctgtcaccaagtcttggtcgagggccgttcacaccttcaactcc
agctcctcccagtactgccgccccatctccacccagagcatcaccagcacggactccgga
gacagcgaagagaactacgtccctatgcaaaacccagtgtctgcgtctcccatccccagc
ggcaccagcagtccggcccctaagaagagcacgggcagcgttgactatctggccctggac
tttcagccgagctccccaagcccccaccgcaagccgtccacgtcctctgtgacttccgat
gagaaggtagactacgttcaggtggacaaggagaagacccaggctctgcagagcaccatg
caggagtggacagacgtgaggcagtcctcggagccttccaagggcaccaagctgtga
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