Panthera leo (lion): 122201660
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Entry
122201660 CDS
T10741
Name
(RefSeq) LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1-like
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
plez Panthera leo (lion)
Pathway
plez00562
Inositol phosphate metabolism
plez01100
Metabolic pathways
plez04014
Ras signaling pathway
plez04015
Rap1 signaling pathway
plez04020
Calcium signaling pathway
plez04024
cAMP signaling pathway
plez04070
Phosphatidylinositol signaling system
plez04919
Thyroid hormone signaling pathway
plez04933
AGE-RAGE signaling pathway in diabetic complications
plez05205
Proteoglycans in cancer
Module
plez_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
122201660
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
122201660
04015 Rap1 signaling pathway
122201660
04020 Calcium signaling pathway
122201660
04070 Phosphatidylinositol signaling system
122201660
04024 cAMP signaling pathway
122201660
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
122201660
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
122201660
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
122201660
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
plez04131
]
122201660
Enzymes [BR:
plez01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
122201660
Membrane trafficking [BR:
plez04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
122201660
Endocytosis
Macropinocytosis
Phospholipase C
122201660
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
122201660
NCBI-ProteinID:
XP_042763446
LinkDB
All DBs
Position
D2:53639306..53864206
Genome browser
AA seq
1994 aa
AA seq
DB search
MVSKGSAAGRGFAGMEEVRQLHVRFCKGIKIWHRXWFLCSLLGREPGEREAGCQLGLCTL
SARLRVGWLFPLSAAHSFTLLKDGCGCWRLKEDQIYNAVRRREEIENTIGSLLHFFTKLP
ASETAHERIRVGPCLKQCVRDTICEYRATLQRTSISQYIVGSLLEATTSLGARSGLLSTF
GGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQEQNIY
RRVLPVDYLCFLTRDLGSPECQTSLPCLKASISASILNSQNGEHNALEDLVMRFNEVSSW
VTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSD
LETMRSLKDAMAQHESSCEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLMKLC
PRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIFQIIRSCSRSLEAEEED
SPSEGNSSRKNSLRDKARWQFIIGDLLDSENDIFEKSKEWDAHGSEEPQKAFDHGTELIP
WYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWTKPTTASLASAKAK
LGVLSNTSEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQNKLGSMFL
SETGVTLLYGLQTTDNRLLHFVAPRHTAKMLFSGLLELTRAVRKMRKFPDQRQQWLRKQY
VSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNVQRNNTLGISTTKKK
KKILIRGESGEAADDEMATRKAKMHRECRSRSGSDPQDMNEQEESEANAIMSPPNTLPSR
RAHSLTTAGSPNLSAGTSSPNRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMKGFQSFM
VSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRAGSESVPLYTNLTIDENTSDL
QPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFGVGIL
ELNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNFASKNDES
QENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGL
PIIYHGHTLTTKIPFKEVVEAIERSAFVNSDLPIIISIENHCSLPQQRKMAEIFKSVFGE
KLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQAY
NGGNANPPPVNNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKRI
KKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNASG
SSRGKERKSRKSIFGNNPGRMSPGETASFNKASGKSSCEGMRQAWEESSSPLNPTTSLSA
IIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLMFWLH
GIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDNME
PAIYSLTIVSGQNVCPSSSTGSPCIEVDVLGMSLDSCHFRTKPIHRNTLNPMWNEQFLFR
VHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRR
MEENSSSSTTPASLMFNSEERKCLQAHRVTVHGVPGPEPFTVFSISGGTKAKQLLQQILT
TEQDTKPIITDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEIMQILSSWFPEEGYVGRI
VLKTQQENLEEKSIVQDDKEVTLSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQ
TLCKAKYSYSILSNPNPSDYVLLEEVVKDTTKKSSTPKSSQRVLLDQECVFQAQSKWKGA
GKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLASPSQVLASEGVQNKEEKP
MGSLSSGDTMEYRQ
NT seq
5985 nt
NT seq
+upstream
nt +downstream
nt
atggtttcaaaaggaagtgcagcaggaagaggctttgcaggaatggaagaggtgaggcag
cttcatgtgagattctgcaaagggattaagatttggcaccgancttggtttctgtgcagc
ctcttaggcagagagcctggggagagggaagcgggctgtcagctggggctttgcacactc
tcagcccgcctcagggttgggtggcttttccctctctctgcagcacacagttttacctta
ttaaaggatggatgtggatgctggaggcttaaggaagaccagatctacaatgcagtgaga
aggagagaagaaatagaaaatacaattggatctcttcttcatttcttcacaaagcttcca
gcctctgaaacagcccatgaaaggattagggttggtccgtgcttaaagcaatgtgtccga
gataccatatgtgagtaccgtgccaccctccagaggacgtccatatctcagtacatcgtg
ggttctctgctagaagcaaccacatctttaggagcaagaagtggcctactcagtaccttt
ggaggatccaccggacgaatgatgctaaaagaacgtcagccaggcacctccatggccaat
tctagtgccctcccttcaagttcagctgggatcagcaaggagctgattgatctgcagccc
ctcattcagttcccagaggaagtcgccagcatcctgatggagcaggagcagaacatttac
cgaagggtcttgccagttgactacctttgcttcttgacccgggacttgggctctccagaa
tgccagacatccctgccctgcctcaaagcgtccatctcagcatcaattcttaactcccag
aacggagaacacaatgccctggaagatcttgtgatgagatttaatgaggtgagctcctgg
gtaacgtggctgatcctcacggcgggctccatggaggagaagcgagaagtcttctcctat
ttggtgcacgtggccaaatgctgctggaacatgggcaactacaatgctgtcatggagttc
ttggccggcctcaggtcaagaaaagttttaaaaatgtggcagtttatggaccagtctgac
ctagagaccatgaggagcctgaaggatgccatggctcagcacgaatcttcctgcgagtac
aagaaggtggtcacgcgggctctgcacatacctggctgtaaggtggttccgttctgtggg
gtgtttctgaaggagctctgtgaagtactggacggagcctccggcctcatgaagctttgc
ccgaggtacaattcccaagaagaaactctagagtttgtagccgattacagcggacaagat
aatttcttacaacgagtgggacataatggcttaaagaattcggagaaagagtccacagtc
aacagcatctttcagatcatcaggagctgcagccgaagtctggaggccgaggaggaggac
agccccagtgaaggaaacagctccaggaaaaattccttaagggataaagcccgatggcag
tttatcattggagacctgttagattctgaaaatgacatctttgagaaatccaaagaatgg
gacgctcacggatcagaagagccacagaaggcctttgaccatgggacagagctaatccca
tggtacgtgctgtccatccgagccgatgtgcaccagttcctgctgcagggggccactgtc
atccactacgaccaggacacgcacctctctgcccgatgcttcctccagcttcagcctgac
aacagtaccttgacctggacaaagcccaccactgcttccctggccagtgctaaagcaaaa
ctcggtgtgcttagtaacacgtctgagcctggcaaattcccgttactgggcaatgctgga
ctaagtggcctggcagagggggtcttggatctgttctcagcaaaagctgtgtacatggga
caccctagcatcgatatacacactgtgtgtgttcagaacaaactgggtagcatgtttctc
tcagagactggtgtgacgctgctctatgggctccagaccacggacaatagattattgcac
tttgtggcacccaggcacacagctaagatgctcttcagtggattgctggaactcacgaga
gccgtgaggaagatgaggaagttccctgaccagagacagcagtggctgcggaaacagtac
gtcagcctctatcaggaagatggacggtacgaaggcccaactttggctcacgccgtggag
ttgtttggtggcaggcggtggagtacacgaaaccccagccccgggacatcagcaaagagt
gccgagaagcccaatgtgcaaagaaacaacaccttgggcataagcactaccaagaaaaag
aagaaaatccttataaggggtgagagcggagaggcagccgatgatgagatggccacccga
aaagccaaaatgcacagagagtgtcgcagccggagtggttctgaccctcaagacatgaat
gaacaagaagaatcagaggcaaatgccatcatgagccctcctaacactctgccttccaga
agagcccactctttgaccacggctgggtcccctaacttgtctgccgggacatcatctccc
aacaggccagtgtcttcccctgtgctgtcttcttcaaacaagagcccgtccagtgcttgg
agcagcagcagctggcacgggcggatcaaaggcggaatgaaaggtttccagagcttcatg
gtttcagacagtaacatgagctttgttgaattcgttgagctgttcaaatcattcagcgtg
aggagccgcaaggacctgaaggacctcttcgacgtctacgccgtgccctgcaaccgagcc
ggctccgaatcggtgccgctctacaccaacctaacaattgacgaaaacaccagcgatctt
cagcctgacctagatttattgaccagaaatgtctcggatttggggttgttcattaagagt
aaacagcagctgtcagacaaccagaggcagatatctgatgccattgctgctgcaagtatc
gtgacaaacggcactggggtcgagagcacatccttgggcgtgtttggggttggcatcctc
gagctcaatgacttcctagtgaactgccaaggagaacactgcacttatgatgaaatcctc
agcatcatccagaagttcgagcctagtgttagtatgtgtcatcagggcctactgtcattt
gaaggatttgcaaggtttctgatggataaagataatttcgcctcgaaaaatgatgagtca
caggaaaacattaaagaactacagctgcccctctcctactattacattgaatcttcacac
aatacctacctcacaggccaccagctcaaaggagagtcctcagtagaactctacagccag
gtcctcctgcaaggctgtaggagcgtagagctggattgttgggatggagacgacgggttg
cccatcatctatcatggacacacgctgacaaccaagatccccttcaaggaggtggttgaa
gccattgaacgcagtgcctttgtcaactctgacctgcccatcatcatatcgattgagaac
cactgctcattgcctcagcaacgaaaaatggcagaaattttcaagagtgtgtttggagaa
aaactggtggctaagttcctgtttgagagtgatttctcagatgacccaatgcttccctca
cccgaccaacttaggaggaaagtgctccttaaaaataagaagctaaaagcccaccaaaca
ccagtggatatcttaaagcaaaaggctcatcagttagcatccatgcaagctcaggcttac
aatggtgggaatgccaaccccccaccggttaataacgaggaagaggaggatgaagaagac
gaatatgattacgactatgaatccctgtctgatgacaacattctagaagacagacctgaa
aataaatcatgtaatgacaagcttcagtttgagtataatgaagaaatccccaagaggata
aagaaagcagataactctgcttgcaacaaaggaaaggtttatgatatggaactgggagaa
gagttttatctccctcagaataaaaaagaaagcagacagattgcaccagagctctctgac
cttgtcatctattgccaagcagtaaaatttccaggcctgtcaactctaaatgcatctggc
tctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcaga
atgagccctggggagacagcatcgtttaacaaagcatctggaaaaagttcctgtgaagga
atgcgacaggcctgggaggaatcttcttcccccctcaacccaaccacatccctcagcgct
atcattagaactcccaaatgttaccatatctcctcgctgaatgaaaatgccgccaaacgt
ctgtgtcgcaggtattctcagaaactgatccagcacaccgcctgtcagctgctgaggact
tacccggctgccactcgcatcgactcctccaaccccaatcccctcatgttctggctccat
gggatacagctcgtggcgctcaactaccagacagatgatctccctttacatttaaatgct
gccatgtttgaagccaacggtgggtgtggttatgttttgaaacccccagttctgtgggat
aagaactgtcccatgtatcagaagttctctcccttagaaagagatctggacaacatggag
cctgccatctactccttaactattgtctctggtcaaaacgtgtgcccgagtagcagcaca
ggaagcccctgtatcgaagtcgatgtgctgggcatgtccctggacagctgccatttccgc
acaaagcccatccaccggaacactctgaaccccatgtggaatgaacagtttctcttccgg
gttcactttgaagatctcgtatttcttcgttttgccgttgtggaaaacaacagctcagct
gtaactgctcagagaatcatcccactcaaggctttaaaacgaggatatcgacatcttcag
ctgcgaaatcttcacaacgaagtcttggaaatctctagtttattcataaacagtaggagg
atggaagaaaattcctccagcagcaccacgccggcctctttgatgtttaattcagaagaa
agaaaatgtttgcaggctcacagagtcacggtgcatggggtcccaggtccagagcccttt
actgttttctccataagtggaggcaccaaagcaaagcagcttctccaacaaattctgacc
actgaacaagacaccaaacctatcatcacagactattttttgatggaagaaaaatatttt
atatctaaagaaaagaatgaatgcaggaaacaaccgttccagagagtcattggtccagag
gaagagattatgcagattttaagcagctggtttccagaggaaggatatgttggcaggatt
gtcttaaaaacccagcaggaaaacctagaagagaaaagcattgttcaagatgacaaagag
gtgaccttgagctcagaggaggagagtttctttgttcaagtgcacgatgtttctccagag
caacctcgaacggtcatcaaagcaccccgtgtcagcaccgcacaggacgtcattcagcag
accttatgcaaagcaaagtattcctacagcatcctgagcaatcccaacccaagtgactat
gtgcttttggaagaggtggtaaaagacacgaccaagaagtcttccaccccaaagtcctcc
cagcgggtccttttggatcaggagtgtgtgtttcaagcccaaagcaagtggaaaggggca
ggaaaattcatccttaagctaaaggagcaggtgcaggcatcccgagaagacaaaaggaaa
ggcatttcttttgcaagtgaatttaagaagttcaccaagtcaactaaacaaccccgagga
ctcgcatcaccttctcaggtcttggcctcagaaggtgtccaaaacaaggaggagaaacct
atgggcagcttgtcctccggtgacaccatggagtatcgacaataa
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integrated database retrieval system
