Panthera leo (lion): 122202378
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Entry
122202378 CDS
T10741
Symbol
TCF7L2
Name
(RefSeq) transcription factor 7-like 2 isoform X1
KO
K04491
transcription factor 7-like 2
Organism
plez Panthera leo (lion)
Pathway
plez04310
Wnt signaling pathway
plez04390
Hippo signaling pathway
plez04520
Adherens junction
plez04916
Melanogenesis
plez04934
Cushing syndrome
plez04936
Alcoholic liver disease
plez05132
Salmonella infection
plez05165
Human papillomavirus infection
plez05167
Kaposi sarcoma-associated herpesvirus infection
plez05200
Pathways in cancer
plez05210
Colorectal cancer
plez05213
Endometrial cancer
plez05215
Prostate cancer
plez05216
Thyroid cancer
plez05217
Basal cell carcinoma
plez05221
Acute myeloid leukemia
plez05224
Breast cancer
plez05225
Hepatocellular carcinoma
plez05226
Gastric cancer
plez05412
Arrhythmogenic right ventricular cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
122202378 (TCF7L2)
04390 Hippo signaling pathway
122202378 (TCF7L2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
122202378 (TCF7L2)
09150 Organismal Systems
09152 Endocrine system
04916 Melanogenesis
122202378 (TCF7L2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122202378 (TCF7L2)
09162 Cancer: specific types
05210 Colorectal cancer
122202378 (TCF7L2)
05225 Hepatocellular carcinoma
122202378 (TCF7L2)
05226 Gastric cancer
122202378 (TCF7L2)
05216 Thyroid cancer
122202378 (TCF7L2)
05221 Acute myeloid leukemia
122202378 (TCF7L2)
05217 Basal cell carcinoma
122202378 (TCF7L2)
05215 Prostate cancer
122202378 (TCF7L2)
05213 Endometrial cancer
122202378 (TCF7L2)
05224 Breast cancer
122202378 (TCF7L2)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
122202378 (TCF7L2)
05165 Human papillomavirus infection
122202378 (TCF7L2)
09171 Infectious disease: bacterial
05132 Salmonella infection
122202378 (TCF7L2)
09166 Cardiovascular disease
05412 Arrhythmogenic right ventricular cardiomyopathy
122202378 (TCF7L2)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122202378 (TCF7L2)
04934 Cushing syndrome
122202378 (TCF7L2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
plez03000
]
122202378 (TCF7L2)
Transcription factors [BR:
plez03000
]
Eukaryotic type
beta-Scaffold factors with minor groove contacts
HMG TCF-1
122202378 (TCF7L2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CTNNB1_binding
HMG_box
HMG_box_2
HMG_WDHD1
Motif
Other DBs
NCBI-GeneID:
122202378
NCBI-ProteinID:
XP_042764640
LinkDB
All DBs
Position
D2:69484006..69696724
Genome browser
AA seq
678 aa
AA seq
DB search
MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
LSPTARTLHFQSGSTHYSAYKTIEHQIAIQYLQMKWPLLDVQAGTLQSRQALKDARSPSP
AHIVQCPLPCCTQGHDCQHLYPPSDFTVSTQVFRDMKRSHSLQKVGEPWCLESNKVPVVQ
HPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQ
IPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSSFLSSRFPPHMVPPHHTLHTT
GIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAK
VVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKK
KRKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCV
RYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPQDAKSQTEQTQPLSLSLKPDPLAHLP
MMPPPPALLLAEAAHGKAPALCPNGALDLPPAALQPPVLSASSLAQPSTSSLHSHSAVAV
AVAGTQPQPLSLVTKSLE
NT seq
2037 nt
NT seq
+upstream
nt +downstream
nt
atgccgcagctgaacggcggtggaggagatgacctaggcgccaacgacgaactgatttcc
ttcaaagacgagggcgagcaggaggagaagagctccgaaaactcctcggcagagagggat
ttagctgatgtcaaatcgtctctagtcaatgaatcagaaacgaatcaaaacagctcctcc
gattccgaggcggaaagacggcctccgcctcgctccgaaagtttccgagataaatcccgg
gaaagtttggaagaagcggccaagaggcaagatggagggctctttaaggggccaccgtat
cccggctaccccttcatcatgatccccgacctgacgagcccctacctccccaacggatcg
ctctcgcccaccgcccgaaccctccattttcagtccgggagcacacattactctgcgtac
aaaacgattgaacaccagattgcaattcagtatctccagatgaaatggccactgcttgat
gtccaggcggggaccctccagagcagacaagccctcaaggatgcccgctctccgtcaccg
gcacacattgtccagtgccccctcccttgctgcactcagggacatgactgtcagcacctc
taccccccctcagacttcactgtcagcactcaagtcttcagggacatgaaaaggagccac
tccctacaaaaggttggggagccctggtgtttggagtcgaacaaagtaccggttgtgcaa
caccctcaccatgtccaccctctcacgccgctcatcacgtacagcaatgaacacttcacc
ccgggaaacccacctccacacttaccagccgacgtagaccccaaaacaggaatcccacgg
cctccgcaccctccagatatatctccgtattacccactatcgcccggcaccgtaggacaa
atcccccatccgctaggatggttagtaccacagcaaggtcagcccgtgtacccaatcacg
acaggaggattccgtcacccctaccccacagctctgactgtcaacgcctccatgtctagc
ttcctgtcttccaggttccctccccatatggtcccaccacatcacactctacacacgacc
ggcatcccccacccggccatagtaacgccaaccgtcaaacaggaatcctcccagagtgac
gtcggctcactccatagctcaaagcatcaggactccaaaaaggaagaagaaaagaagaag
ccccacataaagaaacctcttaacgcgttcatgttgtatatgaaggaaatgagggccaag
gtcgtggccgagtgcacgttgaaagaaagtgccgccatcaaccagatcctggggcgaagg
tggcacgcgctgtccagagaagagcaagcgaaatactacgagctggcccggaaggagcga
cagcttcacatgcagctgtaccccggctggtctgcgcgggataactatgggaagaagaag
aagaggaaaagggacaagcagccaggagagaccaatgaacacagcgaatgtttcctaaat
ccttgcctttcacttcctccgattacagacctgagcgctcctaagaaatgccgagcgcgc
tttggccttgatcaacagaataactggtgcggcccttgcaggagaaaaaaaaagtgcgtt
cgctacatacaaggtgaaggcagctgcctcagtccaccctcttcagatggaagcttacta
gactcgcctcctccctcccccaacctgctaggctcccctccccaagacgccaagtcacag
actgagcagacccagcctctctcgctgtccctgaagcccgaccccctggcccacctgccc
atgatgccgccgccgcccgccctcctgcttgccgaggccgcccacggcaaggcccccgcc
ctctgtcccaacggggccctggacctgccccccgccgccctgcagccgcccgtcctgtcc
gcctcgtctctggcgcagccgtcgacatcttccttacattcccacagcgccgtggccgtg
gccgtggccgggacgcagccccagccgctgtccctcgtgaccaagtctttagaatag
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