Panthera leo (lion): 122203491 Help Entry 122203491         CDS       T10741                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism plez  Panthera leo (lion) Pathway plez00220   Arginine biosynthesis plez00330   Arginine and proline metabolism plez01100   Metabolic pathways plez04020   Calcium signaling pathway plez04081   Hormone signaling plez04145   Phagosome plez04371   Apelin signaling pathway plez04713   Circadian entrainment plez04730   Long-term depression plez04926   Relaxin signaling pathway plez04970   Salivary secretion plez05010   Alzheimer disease plez05014   Amyotrophic lateral sclerosis plez05022   Pathways of neurodegeneration - multiple diseases plez05410   Hypertrophic cardiomyopathy plez05412   Arrhythmogenic right ventricular cardiomyopathy plez05414   Dilated cardiomyopathy plez05416   Viral myocarditis Brite Enzymes [BR:plez01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      122203491 (NOS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Other DBs NCBI-GeneID:  122203491 NCBI-ProteinID:  XP_042766323 LinkDB All DBs Position D3:complement(13821395..13935487) Genome browser AA seq 1429 aa AA seqDB search MENQVFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTRPLAAPTTAVDLSHQSSASREHSPAVDRATGPGNGPQHAQDGGQEAGSLPHTKSRAP GPPGQDSAKKSIQGSQNSDLLKEIEPVLSLLTSGSKGINGGGPSKAETKDAEVQVDRGMD GKSHKPLPLGVENDRVFSDLWGKGHVPVVLNNPYSEKEQPPASGKQSPTKNGSPSKCPRF LKVKNWETDVVLTDTLHLKSTLEMGCTEHICMGSIMLPSQQIRRPEDVRTKEQLFPLAKE FIDQYYSSIKRFGSKAHTERLEEVNKEIETTGTYQLKDTELIYGAKHAWRNASRCVGRIQ WSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLI RYAGYKQPDGSILGDPANVEFTEICVQQGWKPPRGRFDILPLLLQANGNDPELFQIPPEL VLEVPIRHPRFEWFKDLGLKWYGLPAVSNMLLEIGGLEFTACPFSGWYMGTEIGVRDYCD NSRYNILEEVAKNMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIK HMENEYRCRGGCPADWVWIVPPMSGSVTPVFHQEMLNYRLTPSFEYQPEPWNTHVWKGTN GTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHA FDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKS YKVRFNSVSSYSDSHKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVD TLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISN DRSWKRNKFRLTYVAEAPELTQGLSNVHRKRVSAARLLSRQNLQSPKSSRSTIFVRLHTN GNQELQYQPGDHLGVFPGNREDLVNALMERLEDAPPVNQLVKVELLVERNTALGVISNWT DEHRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKW GKNPTIVEVLEEFPSIQMPTTLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAVVSYHTR DGEGPIHHGVCSSWLNRIPADEVVPCFVRGAPSFHLPRNPQVPCILIGPGTGIAPFRSFW QQRQFDIQHKGMSPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPK KYVQDILQEHLAEPVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVF ISRLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS NT seq 4290 nt NT seq  +upstreamnt  +downstreamnt atggagaatcaggtgttcagcgttcagcagatccaacccaacgtcatctccgtccgcctc ttcaagcgcaaggtggggggcctggggttcctggtgaaagagcgggtgagcaagccgccc gtgatcatctccgacctgattcgggggggtgccgcggagcagagcggcctcatccaggcc ggtgacatcatccttgcagtcaacggccagcccctggtggacctgagctatgacagcgcc ctggaggtgctcaggggcatcgcctctgagacccacgtggtcctcattctgaggggcccc gagggcttcaccactcacctggagaccaccttcaccggggacgggacccccaagaccatc cgcgtgacacggcctctggctgcccccaccaccgctgtcgatctgtctcaccagtcatcg gccagcagagagcactcaccggcagtggacagggccacgggtcctggcaatgggccgcag cacgcccaagacggtgggcaggaagccggctctctcccccataccaagagccgggctccc gggcccccgggccaggactctgccaagaagagcatccagggcagccagaacagtgatttg ctcaaagagatagaacctgtactgagccttctcaccagcgggagcaaagggatcaatggc gggggaccttccaaggcagagacgaaggatgcagaagtccaggtggacagaggtatggat ggcaagtcacacaagccactgcccctgggcgtggagaatgaccgagtcttcagtgacctg tgggggaagggccacgtgcctgtcgtcctcaacaacccgtattcagagaaggagcagccc cctgcctcaggaaaacagtctcctacaaagaacggcagcccctccaagtgcccccgcttc ctcaaggtcaagaactgggagaccgacgtggtcctcactgacacccttcaccttaagagc acactggaaatgggctgcaccgagcacatctgtatgggctccatcatgctcccctctcag cagatacgaaggcctgaagacgtccgcacaaaagaacagctcttccctctcgccaaagag ttcattgaccagtactactcatcaattaaaaggtttggctccaaagcccacacggagagg ctggaagaggtcaacaaagagatcgaaaccaccggcacctaccagctcaaagacacggag ctcatctacggggccaagcatgcctggcggaacgcctcccgctgcgtgggcaggatccag tggtccaagctgcaggtgttcgatgcccgcgactgcaccacggctcacgggatgttcaac tacatctgcaaccacatcaagtatgccaccaacaaagggaacctcagatccgccatcacc atattcccccagaggacggacggcaagcacgatttccgagtctggaactctcagctcatc cgctatgccggctacaagcagcctgatggctccatcctgggggacccagccaatgtggaa ttcacagagatctgtgtgcagcagggctggaaacccccaagaggccgcttcgatatcctg ccactcctgctccaggccaacggcaacgatcccgagctcttccagatccccccagagctg gtgttggaagtgcccatcaggcaccccaggtttgagtggttcaaggatctgggcctgaag tggtatggcctccccgctgtgtccaacatgctgctggagattggcggcctggagttcacc gcctgtcccttcagcggctggtacatgggcacagagattggcgtccgcgactattgtgac aactctcgatacaacatcctggaggaagtggccaagaacatgaacttggacatgaggaag acgtcctccctgtggaaggaccaagcactggtggaaatcaacattgctgttctctacagc ttccagagtgacaaagtgaccatcgttgaccaccactctgccacagaatccttcatcaag cacatggagaatgaataccgctgccgggggggctgccccgccgactgggtgtggattgtg ccccccatgtctggcagtgtcacccctgtcttccaccaggagatgctcaactaccgactc accccgtccttcgaataccagcctgagccttggaacacccacgtctggaaaggcaccaat ggaacccccacaaagcggcgagccatcggcttcaagaagctggcagaagccgtcaagttc tcagccaagcttatggggcaggcaatggccaagagggtcaaggcgaccatcctttatgcc acagagacgggcaagtcacaggcctatgctaaaaccttgtgtgagatcttcaaacatgcc tttgatgccaaggtgatgtccatggaagaatatgacattgtacacctggaacatgaaact ctggtcctagtggttaccagcacttttggcaatggcgaccccccagagaatggggagaaa ttcggctgtgctttgatggaaatgaggcaccccaactccgtgcaggaggaaaggaagagc tacaaggtccgattcaatagtgtttcctcgtattctgactcccataaatcatcaggcgac gggccagacctcagagacaactttgagagtgctggacccctggccaacgtgaggttctcc gtatttggccttggctcccgggcttaccctcatttctgcgcctttggacatgccgtggac accctcctggaggagctgggaggagagaggatcctgaagatgagggagggagacgagctc tgtgggcaggaagaggctttcaggacctgggccaagaaggtcttcaaggcagcctgcgat gtgttctgcgtgggagatgacgtcaacatcgagaaggcaaacaactccctcatcagcaac gaccgcagctggaagagaaacaagttccgcctcacctacgtggccgaagctccggaactt acacaaggtctatccaatgtccacagaaagcgggtctcggccgctcgactcctcagccgc caaaaccttcagagccctaaatccagccgatcaacgatcttcgtgcgtctccacaccaat gggaatcaggagctgcagtaccagcctggggaccacctgggcgtcttccctggcaaccgc gaggacctcgtgaacgccctgatggagcggctggaagatgctcccccagtcaaccagctg gtgaaggtggaacttctcgtggagcggaacacggctttgggcgtcatcagtaactggaca gatgagcaccgcctcccgccctgcaccatcttccaggccttcaagtactacctggacatc accacgccgcccacgccactgcagctgcagcagtttgcgtccctggccaccagcgagaaa gagaagcagcgactgttggtcctcagcaagggcttgcaggagtacgaggaatggaaatgg ggcaagaaccccaccatcgtggaggtgctggaagagttcccgtccatccagatgcccacc accctgctcctgacccagctgtccctgctgcagcctcgatactattcaatcagttcttcc ccagacatgtaccctgacgaggtgcacctcaccgtggccgttgtctcctaccacacccga gatggagaaggaccaattcaccacggcgtgtgctcctcctggctcaatcggataccggct gacgaagtggtcccctgtttcgtgagaggagcacccagcttccacctgccccgaaatccc caagtgccctgtatcctcattggcccaggcactggcattgcccctttccgaagcttctgg cagcagcgacaatttgatatccagcacaaaggaatgagcccctgccccatggtcctggtg tttgggtgccggcaatccaagatagaccacatctacagggaggaaactctacaggccaaa aacaagggggtcttcagagaactctacacggcctactcgcgggagccagacaaaccaaag aagtacgttcaggacatcctgcaggagcacttggcagaacctgtgtaccgagccctgaag gagcaagggggccacatttacgtctgcggggacgtcaccatggccgccgatgtcctcaaa gccatccagcgcatcatgacccagcaagggaaactctcagcggaggatgccggcgtgttc atcagcaggctgagggatgacaaccggtaccatgaggatattttcggggtcaccctgcga acatatgaagtgaccaaccgccttagatctgaatccattgccttcattgaggagagcaaa aaagacactgatgaagttttcagctcctaa

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