Panthera leo (lion): 122203752
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Entry
122203752 CDS
T10741
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
plez Panthera leo (lion)
Pathway
plez04020
Calcium signaling pathway
plez04022
cGMP-PKG signaling pathway
plez04024
cAMP signaling pathway
plez04148
Efferocytosis
plez04260
Cardiac muscle contraction
plez04261
Adrenergic signaling in cardiomyocytes
plez04380
Osteoclast differentiation
plez04919
Thyroid hormone signaling pathway
plez04972
Pancreatic secretion
plez05010
Alzheimer disease
plez05017
Spinocerebellar ataxia
plez05022
Pathways of neurodegeneration - multiple diseases
plez05410
Hypertrophic cardiomyopathy
plez05412
Arrhythmogenic right ventricular cardiomyopathy
plez05414
Dilated cardiomyopathy
plez05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
122203752 (ATP2A2)
04024 cAMP signaling pathway
122203752 (ATP2A2)
04022 cGMP-PKG signaling pathway
122203752 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
122203752 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
122203752 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
122203752 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
122203752 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
122203752 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
122203752 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
122203752 (ATP2A2)
05017 Spinocerebellar ataxia
122203752 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
122203752 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
122203752 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
122203752 (ATP2A2)
05414 Dilated cardiomyopathy
122203752 (ATP2A2)
05415 Diabetic cardiomyopathy
122203752 (ATP2A2)
Enzymes [BR:
plez01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
122203752 (ATP2A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
122203752
NCBI-ProteinID:
XP_042766760
UniProt:
A0A8C9D3D0
LinkDB
All DBs
Position
D3:8250950..8309554
Genome browser
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGYFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKVMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggctacttcggcgtcaacgag
agcacagggctgagcctggagcaggtcaagaagctcaaggagagatggggctccaacgag
ttaccggctgaagaaggaaaaaccttgttggaacttgtgattgagcagtttgaagactta
ttagttagaattttattgctggcagcttgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgctattgtgggtgtatggcaggaaagaaatgctgagaatgctattgaagcccttaag
gaatatgagcctgaaatgggcaaagtatatcgacaggacagaaagagtgtacagcggatt
aaagctaaggacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctactactctgagagttgaccagtccattctc
acaggtgagtctgtgtctgtcatcaagcacactgaccctgtcccagacccacgggccgtc
aaccaagataagaagaacatgctgttttctggaacaaacattgctgctggcaaagccatg
ggagtggtggtggcgactggagttaacacagaaatcggcaagatccgggatgagatggtg
gcaacagaacaggagagaacacccctccagcagaaactagacgagtttggggagcagctt
tccaaagtcatatcccttatttgcattgcagtctggatcataaacattgggcacttcaat
gacccagttcacggaggctcctggatcaggggtgctatttactactttaaaattgcggtg
gccctggctgtggcggccattcctgaaggtctgcctgctgtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgccattgttcgaagtctcccttctgtggaa
acccttggttgtacttctgttatctgctcagacaagactggtacgcttacgacgaaccag
atgtcagtgtgcaggatgttcattctggacaaggttgagggggatacttgttcccttaat
gagtttaccataactgggtcaacatatgcacctattggagaagtgcataaagatgataaa
ccagtgaaatgtcatcaatatgatggtcttgtggaattggcaacaatttgtgctctttgt
aatgattctgcattggattacaatgaggcgaagggcgtgtatgaaaaagttggggaagct
acagagactgctctcacttgcctagtagagaagatgaatgtatttgataccgaattgaag
ggtctttctaaaatagaaagagcaaatgcctgcaactcggtcataaagcagttaatgaaa
aaagaatttactctcgagttttcacgcgatagaaaatcaatgtcagtttattgtacacca
aacaaaccaagccggacatcgatgagcaaaatgtttgtgaagggcgctcccgaaggtgtc
attgacaggtgcacccacattcgggttggaagtaccaaagtccctatgacccctggagtc
aaacagaaggtcatgtctgtcatcagggaatggggtagtggcagcgacacactgcggtgc
ctggctctggccactcatgacaacccactgagaagagaagaaatgaaccttgaggactct
gccaactttatcaaatatgagactaatctgactttcgttggctgtgtgggcatgctggac
cctccaagaattgaagtggcctcttctgtgaagctttgccggcaagcaggcatccgggtg
atcatgatcacaggagacaacaaaggcactgctgtggccatctgtcgccgcattggcatc
ttcgggcaggacgaggatgtgacgtcaaaggcttttacgggtcgggagtttgatgagctc
agtccttcagcccaaagagatgcctgcttgaatgcccgctgttttgctcgagttgagcct
tcccacaagtcaaaaattgtagagtttcttcagtcttttgatgagattacagctatgacc
ggggatggtgtgaatgatgctcccgccctgaagaaatcggagattggcattgccatgggc
tctggcacggcagtggctaaaaccgcctctgagatggtcctggctgatgacaacttctcc
accattgtggctgctgtcgaggaggggcgggcgatttacaacaatatgaagcagtttatc
cgctacctcatctcttcgaatgtgggggaagttgtctgtattttcctgactgcagccctt
ggatttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagacggc
ctgcctgccactgcactggggtttaacccacctgatctggacatcatgaacaaaccaccc
cggaacccgaaggaaccactgatcagcggatggctctttttccgttaccttgctattggc
tgttacgttggcgctgctactgtgggtgctgccgcgtggtggttcattgctgccgacggg
ggtccgagggtgtccttctaccaactgagccacttcctacagtgtaaagaagacaacccg
gactttgaaggagtggattgtgcaatctttgagtccccgtacccgatgacaatggcgctg
tctgttctagtaaccatagagatgtgtaacgccctcaacagcttgtctgaaaaccagtct
ctgctgaggatgcccccttgggagaacatctggctcgtgggctccatctgcctgtccatg
tcgctccatttcctcatcctctacgtggaacctttgccacttattttccagatcacaccg
ctgaacttgacccagtggctgatggtgctgaaaatctccttgcctgtgattctaatggat
gagacactcaagtttgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gccaccaaatcctgctcgttctcggcatgcaccgatgggatttcctggccgtttgtgctg
ctcataatgcccctggtgatctgggtctatagcacagacactaactttagtgatatgttc
tggtcttga
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