Panthera leo (lion): 122203754
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Entry
122203754 CDS
T10741
Symbol
ATP2B2
Name
(RefSeq) plasma membrane calcium-transporting ATPase 2 isoform X1
KO
K05850
P-type Ca2+ transporter type 2B [EC:
7.2.2.10
]
Organism
plez Panthera leo (lion)
Pathway
plez04020
Calcium signaling pathway
plez04022
cGMP-PKG signaling pathway
plez04024
cAMP signaling pathway
plez04261
Adrenergic signaling in cardiomyocytes
plez04925
Aldosterone synthesis and secretion
plez04961
Endocrine and other factor-regulated calcium reabsorption
plez04970
Salivary secretion
plez04972
Pancreatic secretion
plez04978
Mineral absorption
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
122203754 (ATP2B2)
04024 cAMP signaling pathway
122203754 (ATP2B2)
04022 cGMP-PKG signaling pathway
122203754 (ATP2B2)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
122203754 (ATP2B2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
122203754 (ATP2B2)
09154 Digestive system
04970 Salivary secretion
122203754 (ATP2B2)
04972 Pancreatic secretion
122203754 (ATP2B2)
04978 Mineral absorption
122203754 (ATP2B2)
09155 Excretory system
04961 Endocrine and other factor-regulated calcium reabsorption
122203754 (ATP2B2)
Enzymes [BR:
plez01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
122203754 (ATP2B2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Cation_ATPase_C
E1-E2_ATPase
ATP_Ca_trans_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
EMC3_TMCO1
Motif
Other DBs
NCBI-GeneID:
122203754
NCBI-ProteinID:
XP_042766766
UniProt:
A0A8C8WBI8
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Position
A2:complement(51504725..51621546)
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AA seq
1243 aa
AA seq
DB search
MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL
KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG
LSFYHPPGENNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR
GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS
LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKD
KKGVKKGDGLQLPAADGAAGSNAVDSANTSLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ
PLKSAEGGDADDKKKANMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT
FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL
VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLVN
AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRTQMPEEKLYKVY
TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV
IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNDLTCICVVGIEDPVRPEVPEAIRKC
QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK
IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA
GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT
QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV
YQLTLIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER
NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV
IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ
IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS
SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL
NT seq
3732 nt
NT seq
+upstream
nt +downstream
nt
atgggtgacatgaccaacagcgatttttactccaaaaaccaaagaaatgagtcgagccat
gggggcgagttcgggtgcacaatggaggagctccgctccctcatggagctacggggcacc
gaggctgtggtcaagatcaaggagacttatggggacactgaagccatctgccggcgcctc
aagacttcacctgtggaaggtttgccgggcaccgctccagatctggaaaagagaaagcag
atttttgggcaaaactttatacctccaaagaagccaaaaaccttcctgcagctggtgtgg
gaggcactgcaagatgtgacactgatcatcctggaaatcgcggccatcatctccctgggg
ctgtccttttaccacccgcctggagagaacaatgaaggatgtgcgacggcccagggaggg
gcagaggatgaaggggaggcggaggcgggctggatcgagggggcggccatcctcctctct
gtcatctgtgtggtcctggtcacggccttcaatgactggagcaaagagaagcagttccgg
ggcctgcagagccgcattgagcaggagcagaagttcaccgtggttcgggctggccaggtg
gtccagatccctgtggccgagattgtggttggggacatcgcccaggtcaaatatggtgac
cttctccctgctgacggcctcttcatccagggcaatgacctcaaaatcgacgaaagctcc
ctgacgggagagtctgaccaggtgcgcaagtccgtggacaaggaccccatgctgctgtca
gggacccacgtgatggagggctctggacggatggtagtgaccgcagtgggtgtgaattct
cagactggcatcatctttaccctgctgggggctggcggtgaggaggaagagaagaaagac
aagaaaggtgtgaagaagggggatggccttcagctaccagcggccgatggtgcagcaggc
tcaaatgctgtagatagtgcaaataccagcctagtcaatggtaaaatgcaggatggcaat
gtggacgccagccagagcaaagccaaacagcaggacggggcagccgccatggagatgcag
cccctcaagagtgccgagggcggcgatgccgacgacaaaaaaaaggccaacatgcacaag
aaggagaagtctgtgctgcagggaaagctcaccaagctggctgtgcagataggcaaggca
ggactggtgatgtcagccatcacagtgatcatcctggtgctctacttcaccgtggacacc
ttcgtggtcaacaagaagccgtggttacccgagtgcacgcccgtctacgtgcagtacttt
gtcaagttcttcatcatcggtgtgacagtgctggtggtggccgtgcccgaggggctccct
ctggccgtcaccatctcactggcctactctgtgaagaaaatgatgaaagacaacaacctg
gtacgccacctggatgcctgcgagaccatgggcaatgccaccgccatctgctcagacaag
acaggcacactgaccaccaatcgcatgacagtcgtgcaggcctacgtgggcgatgtccac
tacaaggagatccccgaccccagctccatcaacaccaagaccatggagctgctcgtcaac
gccattgccatcaacagcgcctacaccaccaagattctgcccccggagaaggagggtgcc
ctgcctcggcaggtgggcaacaagacagagtgcggcctgctgggcttcgtgctggacctg
aagcaggattatgagcccgtgcgcacccagatgccagaggagaagctgtacaaggtgtac
accttcaactctgtgcgcaagtccatgagcacagtcatcaagctgccggacgagagcttc
cgcatgtacagcaagggtgcttctgagatcgtgctcaagaagtgctgcaaaatcctcaac
ggggcaggggagccccgggtcttccggccccgcgaccgggatgagatggtgaagaaggtg
atcgagcccatggcctgtgatgggctccgcaccatctgtgtggcctaccgtgacttcccc
agcagcccggagcctgactgggacaatgagaatgacatcctcaacgacctaacctgtatc
tgtgtggtgggcatcgaggaccccgtgcggcccgaggtcccagaagccatccgcaagtgc
cagcgagcgggcatcacagtccgcatggtcaccggtgacaatatcaacacggcccgggcc
atcgccatcaagtgtggcatcatccatcctggggaggactttctgtgcctggagggcaag
gagtttaaccggaggatccgcaacgagaagggggagattgaacaagagcgaattgataag
atctggccaaagctacgggtgctggctcgctcctcccccacggacaagcataccctcgtc
aaaggtatcatcgacagcacacacacggagcagcgacaggtggtggccgtgacaggggat
ggcaccaacgacgggcctgcgctcaagaaggctgacgtgggcttcgccatgggcatcgca
ggcacggatgtggccaaggaggcctcggacatcatcctgacggatgacaacttcagcagc
atcgtcaaggcagtgatgtggggccgcaacgtctatgatagcatctccaaattcctgcaa
ttccaactaacagtcaacgtagtggctgtgattgtggccttcacaggcgcctgcatcacg
caggactcccctctgaaggccgtgcagatgctctgggtaaacctcatcatggacacgttc
gcctcgctggccctggccactgagccgcccaccgagaccctgcttctgaggaagccatac
ggccgtaacaagcccctcatctctcggaccatgatgaagaacatcctgggccatgccgtc
taccagctcaccctcatcttcaccctgctttttgttggcgagaagatgttccagatcgac
agtgggaggaacgcacccctgcactcgccaccctcggagcactacaccatcatcttcaac
accttcgtcatgatgcagctcttcaacgagatcaacgcccgcaagatccatggcgagcgc
aatgtctttgatggcatcttccggaacccgattttctgcaccatcgtgctgggcaccttt
gccatccagatagtgatcgtgcagtttggggggaagccgttcagctgctctccgctgcag
ctggaccagtggatgtggtgcatattcatcgggttgggagagctcgtctggggtcaggtc
atcgccaccatcccgaccagcaggctcaagttcctcaaggaggcggggaggctcacgcag
aaggaggagatcccagaggaggagctgaatgaggacgtggaggagatagaccacgctgag
agggagctgcggcggggccagatcctgtggttccgaggcctgaatcggatccagacccag
attcgcgtcgtgaaggcgttccgtagctctctctatgaaggtctagaaaagcctgagtct
cgaacctccatccataatttcatggctcaccccgaattccggatcgaagattcacagccc
cacatccccctcattgacgacaccgacctggaagaagatgccgcactcaagcagaactcg
agcccgccgtcatcgctcaacaagaacaacagcgccatcgacagcgggatcaatctgacg
actgacacaagcaaatcagctacctcttcaagtccagggagccccatccacagcctggag
acgtcgctttag
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