Panthera leo (lion): 122204045
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Entry
122204045 CDS
T10741
Symbol
LAMA1
Name
(RefSeq) laminin subunit alpha-1
KO
K05637
laminin, alpha 1/2
Organism
plez Panthera leo (lion)
Pathway
plez04151
PI3K-Akt signaling pathway
plez04510
Focal adhesion
plez04512
ECM-receptor interaction
plez04820
Cytoskeleton in muscle cells
plez05145
Toxoplasmosis
plez05146
Amoebiasis
plez05165
Human papillomavirus infection
plez05200
Pathways in cancer
plez05222
Small cell lung cancer
plez05410
Hypertrophic cardiomyopathy
plez05412
Arrhythmogenic right ventricular cardiomyopathy
plez05414
Dilated cardiomyopathy
plez05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
122204045 (LAMA1)
09133 Signaling molecules and interaction
04512 ECM-receptor interaction
122204045 (LAMA1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
122204045 (LAMA1)
09142 Cell motility
04820 Cytoskeleton in muscle cells
122204045 (LAMA1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122204045 (LAMA1)
09162 Cancer: specific types
05222 Small cell lung cancer
122204045 (LAMA1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
122204045 (LAMA1)
09174 Infectious disease: parasitic
05146 Amoebiasis
122204045 (LAMA1)
05145 Toxoplasmosis
122204045 (LAMA1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
122204045 (LAMA1)
05412 Arrhythmogenic right ventricular cardiomyopathy
122204045 (LAMA1)
05414 Dilated cardiomyopathy
122204045 (LAMA1)
05416 Viral myocarditis
122204045 (LAMA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Laminin_G_1
EGF_laminin
Laminin_G_2
Laminin_B
Laminin_N
Laminin_I
EGF_LMN_ATRN
Laminin_II
Laminin_G_3
HAD_2
DUF5994
Motif
Other DBs
NCBI-GeneID:
122204045
NCBI-ProteinID:
XP_042767144
LinkDB
All DBs
Position
D3:37279630..37447501
Genome browser
AA seq
3085 aa
AA seq
DB search
MRGGGAGVALLASLLWVAARCQQRGLFPAILNLASNAHISTNATCGERGPEMSCKLVEHV
PGRPVRNAQCRICDADSANPKERHPISHAIDGTNNWWQSPSIQNGREYHWVTITLDLRQV
FQVAYVIIKAANAPRPGNWILERSLDGTKFSPWQYYAVSDTECLTRYNITPRRGPPTYRA
DDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNA
DLMTLSHRDPKDLDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNT
CGESCNRCCPGYHQQPWRPGTISSGNTCEKCNCHNKAQDCYYDGNVANQRRSLNTAGQFR
GGGVCISCLQNTMGINCETCIDGYYRPHDVSPYDDNPCRPCDCDPFGSLSSVCIKDKPQS
GLHKGKWPGQCPCKEGYAGEKCDHCQFGYKAYPACVRCECSRAGSVNEDPCSEPCLCKEN
VEGENCDLCKPGFYNLKERNPEGCSECFCFGVSDVCDSLSWSISQVKDMSGWLVTDLISP
SKIPSQQDALGGRHQISINNTVATQRLTSEYYWSAPEAYLGNKLTAFGGFLKYTVSYDIP
VETVDGDLMSHTDVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPENFRDFNNKKEIDR
DQLMTVLANVTHLLIRANYNSAKMALYRLDSVSLDTASPNVIDLALATEVEHCECPQGYA
GISCESCLPGYYRVDGILFGGICQPCECHGHAAECDIHGVCFACKHNTTGDHCEQCAPGF
YGLPSRGTPRDCQQCACPLSTASNNFSPTCHLEDGDEVVCDQCAPGYSGAWCERCADGYY
GNPTVPGESCVPCDCSGNVDPLEAGHCDSVTGECLKCIGNTAGAHCERCADGFYGDAVKA
KNCRACECHGKGSLSGVCHLETGVCDCKPHVTGQQCDRCSHGYYGLDTGLGCLPCNCSTP
GSLSDDCTEEGRCHCVPGVAGEKCDRCARGFYAFQDGGCTPCDCAHTQHTCHPESGQCIC
PPHTRGASCDECEDGYWGRDPELGCQACNCSAVGSASHRCDVLTGRCRCKPAFGGPSCHQ
CSLGYRDFPDCVPCDCDPRGTSADTCDEEQSLCSCAEETGICSCKENVFGLQCSECRAGT
YALRADDPLGCTPCFCFGLSQVCSELEGYVRTPITLGSGQPLLRVVSQSNLRGTTQGVYY
QAPDVLLDAVTVRQHIHTEPFYWRLPERFQGDQLLAYGGRLRYSVAFYSSNGMGTFNLEP
QVLIKGGRTRKQVIYVDVPAPENGVRQDQEVGMKENFWRYFNSVSEKPVTRSDFMSVLSN
IEYILIKASYGQGLQQSRISNISMEVGKKADKLRPGQKAASRLEKCLCPPGTAGFSCQDC
APGYHRGELPQGGGRGPRPLLAPCVPCSCNNHSDACDPETGRCLNCSHSTTGDHCDLCAP
GYFGKVTGSASDCSVCACPRSHPASFSPTCVLEGDHDFRCDACILGYEGQYCERCSSGYH
GNPRALGGTCQRCDCSPSGSVHGDCDRRSGQCVCRPGATGLRCEECEPRHILLESDCVSC
DDECVGVLLNDLDNIGDAILSVNLTGVIPVPSGILSNLENTTKYLREALLKENTRKDLAE
DQLEDVAKQTDHLLRELTRVLTSSQHVTRATEGILDKSQDLMTFTEKLQRTIQEIIEKAA
TLNQTLDEDFQLPSSTLQNMQKNITSLLEVIQKRHFVQLQQKAMLELKAAEDLLSQIQKN
YQKPQKELEVLKEAASSLLSKRSSELQAARDLVREAEVKNQESDRLLHIVSANLREFNDK
TVRVQQEQNLTSTLIARGRRLLDAVTAPADAVGDALAQLERHRDELLLWTAKIRRHVDDL
VMQMSQRRALDLVYRAEDHAAELQRLAGALDSGLGSVRHVSLNATSATHVHSNIRSMIEE
SEKVAKDALKIVTTASLFSESLAPNGKVALQRSSRFLKEGSSLSRKHQGITLELSKWKNT
AKRFQENAHTITRRTNESLSILRAFPEGVRDKGAKIKELASSANRSAASTLKKVVGLSKE
LLNTSTGLSRVNAALQETNKLLQDSSMTTLLAGRRVKDAETQASLLFDRLKPLKILEENL
SRNLSEIKLLISQARKQAASIKVAVSADRDCVRAYQPQISSTNYNTLTLNVKTSEPDNLL
FYLGSSTSSDFLAVEMRRGKVAFLWDMGSGSTRLEFPDFRADDNKWHSIYVTRFGNIGSL
SVKEMSATQKPSTKTSKSPGTAKVLDINNSTLMFVGGLGGQIKKSPAVKVTHFKGCMGEA
FLNGQSIGLWNYVEREGKCHGCFGSPQNEDSSFHFDGSGYSVVEKTLRATVTQIIMLFST
FSPNGLLLYLASNGTKDFVSIELVRGRVRVTVDLGSGPLALITDRRYNNGTWYKIAFQRN
RKQGLLAVIDAYNTSYKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRKGVTSKSYV
GCIKNLEISRSTFDLLRNSYGVRKGCILEPIRTVSFLKGGYVELSPRSLLPESELLATFA
TKNSSGIILAALGRHGEKQGHRQAHGQPSQPFFSIMLIEGHIEVHVNSGDGANLRRAVLR
APKGTYGDGQEHSISLMRTGSIITVQMDETNPVEMKLGPSAESRTINVSSLYIGGVPEGE
GTSVLKMGRSFHGCIKNLIFNMEHLDFTSAVGYEQVDLDTCLLSERPKLALHGEDSELPP
EPQPLPSLGQCAVDRAPEYIPNAHQFGLMQSSHFVLPFNQLAVRKRLSVQLSIRTLASSG
LIYYMAHQNQVDYATLQLHGGHLHFMFDLGKGRTKVSHPAVISDGRWHTVKTEHFKRKGF
MTVDGQESPTVTAVGDGTMLDVEGKLYLGGLPSEYRARNIGNITHSVPACIGEVILNGKQ
LDKSSPVSAFAVSRCYAVAQEGTFFEGSGYAALVKEGYKVRSDVNITLEFRTTSENGVLL
GISSAKVDAIGLEIVNGKILFHVNNGAGRITATYKPKATSTLCDGRWHTLQAQKSKHRLV
LIVDGNAAHAESPHTQSTSADTNNPIYVGGYPADVKQNCLSSQTSFRGCLRKLTLIKGPQ
VQSYDFSRAFDLQGVFPHSCPGSEP
NT seq
9258 nt
NT seq
+upstream
nt +downstream
nt
atgcgcggcggtggcgcgggggtcgcgctcctggcctcgctgctctgggtcgccgcgcgg
tgccagcagagagggctgtttcctgccattctcaatcttgccagcaacgcgcacatcagc
accaacgccacctgtggggagcgggggcccgagatgtcctgcaagcttgtggagcacgtg
cccggtcgacccgtgcgcaacgcacagtgccggatctgcgacgcggacagcgccaacccc
aaagaacgccacccaatatcccatgcaatcgatgggaccaacaactggtggcaaagcccc
agtattcaaaacgggagagaatatcactgggtcacaatcactctggacttaagacaggtc
tttcaagttgcctacgtcatcatcaaagctgctaatgcccctcgacccggaaactggatt
ttggagcgttctctggatggcaccaagttcagcccctggcagtactatgcagtcagtgac
acggagtgtttgacccgttacaatatcactccaagacgggggccacccacttacagggct
gatgatgaagtgatctgcacctcctactattccagactggtgccgcttgagcacggagag
attcatacgtcgctaatcaacggcagaccgagcgctgatgatctctcacccaagctgttg
gagtttacttctgcacgatatatccgccttcgcttacagcgtatcagaaccctcaatgcc
gatcttatgaccctcagccaccgagaccctaaagacctcgatcctattgttacaagacga
tattactattcaatcaaagacatttctgttggcggaatgtgtatttgttatggccatgcc
agtagctgcccatgggatgaaactacaaagaagctgcagtgtcagtgtgaacataacacc
tgtggagagagctgcaataggtgttgtccgggatatcaccagcagccgtggcggcccggc
accatttcttctggtaacacgtgtgaaaagtgtaattgtcacaataaagcccaagactgt
tactatgatggaaatgttgcaaatcagaggagaagcttgaataccgcgggacagttcaga
ggaggcggggtgtgcatcagctgcctgcagaacaccatgggaatcaactgtgaaacctgt
atcgatggatattacagaccacacgacgtatctccttatgatgacaacccttgtcgtccc
tgtgactgtgacccttttgggtccctcagttctgtctgtattaaggataagcctcaatct
ggcttacacaaagggaagtggccaggtcaatgtccatgcaaggaaggctacgcaggagaa
aaatgtgatcactgccaatttggttataaggcttacccagcctgtgtccgctgtgagtgt
agccgggctggcagtgtgaacgaggacccatgctcagagccctgtctctgcaaggaaaat
gttgaaggggaaaattgtgacctctgcaagccaggattctataacttgaaggagagaaac
cccgagggctgctcggagtgcttctgctttggcgtttctgatgtctgcgacagcctttct
tggtccatcagtcaggtgaaagacatgtctgggtggcttgtcaccgacctgatcagtccg
agcaagatcccatctcagcaagacgcactgggtgggcgtcatcagattagcatcaacaac
acggtggccacgcagaggctgacttccgagtattactggtcggcaccggaggcctacctc
ggaaataagctgactgctttcggtggattcctgaagtacacagtgtcctatgatattcca
gtggagacagtggatggcgacctcatgtcgcacaccgatgtcatcatcaagggaaatgga
ctcactttaagcacccaggctgagggcctgtcattacagccctatgaagagtatttaaac
gtggtcagacttgtgccagagaacttccgagattttaataacaaaaaggagatagatcgt
gaccaactgatgactgtccttgccaatgtgacacatctcctgatcagagccaactataat
tctgcaaaaatggctctttacaggttggattctgtctctttggacacagccagccctaac
gttatagacctggcactggccacggaggtggaacactgcgaatgtccccaaggctatgca
gggatctcctgtgagtcctgtctccctggctattatcgtgtggatggaatactctttgga
ggaatttgtcaaccctgtgaatgccatggccatgcagctgaatgcgatatccacggcgtt
tgctttgcgtgcaagcacaacaccaccggggaccactgtgagcagtgcgcaccgggcttc
tacgggctgccttcccgagggactcctagggactgccagcagtgtgcctgccccctctcc
acagcctccaacaatttcagccccacctgccacctagaagatggggacgaagtggtctgt
gaccagtgtgcaccgggatactcgggagcttggtgcgagagatgcgcagatggttactat
ggaaacccaacagtgcccggggaatcctgtgttccctgcgactgcagcggcaatgtggat
cccttagaggccggtcactgtgactccgtcaccggagagtgcctgaaatgcattgggaac
acggctggtgcccactgtgagaggtgtgcggacggcttctatggggatgccgtgaaggct
aaaaattgccgcgcctgtgaatgccatggaaaaggctccctttctggtgtctgccatctg
gagactggagtctgtgactgcaaaccgcatgtgactggacagcagtgtgaccggtgctcg
catggctattatgggctggacacagggcttgggtgcttgccctgtaactgcagcacgcca
ggctccctgtcggatgactgcacggaggaaggccgatgtcactgtgtgccaggtgtggct
ggggaaaagtgcgacaggtgtgcgcgtggcttctatgcgttccaggacggcggctgtaca
ccctgtgactgcgcccacacgcagcacacttgtcacccggaatcggggcagtgcatctgc
cctcctcatactcggggcgcatcctgtgacgaatgtgaggatggatactggggccgcgac
ccagagctcggatgccaggcctgcaattgcagtgctgtcgggtcagccagtcatcggtgc
gatgtgctcactggccgttgccgatgtaagccagcgttcggtggaccgagctgccaccag
tgctccctggggtacagagactttccagactgcgtgccctgtgactgtgacccaagaggg
acctcggcagacacctgtgatgaggaacagagtctttgcagctgtgcagaggaaaccggt
atctgctcttgcaaggaaaatgtgtttggcctgcagtgcagcgagtgtcgagccggcacc
tatgctctccgcgccgacgaccctctggggtgcaccccctgcttctgcttcgggctgtca
caagtctgctcagagctcgagggttatgtgaggaccccgataacgctgggctcgggtcag
ccgctcctgcgtgtggtttctcagagcaacctcaggggcacgacccagggggtgtattac
caggctcctgatgtcctcctggacgccgtgactgtcaggcagcatattcacacggagccg
ttttactggagactgccagagcggttccagggagaccagctcctggcctacggtggcaga
ctgaggtacagcgtggccttctattcttccaatggcatgggcaccttcaaccttgaaccc
caggtgctcatcaaaggaggccggaccagaaagcaagtcatctacgtggatgtgccggca
ccggagaatggtgtgcgacaagaccaagaagtgggaatgaaagagaatttttggagatat
tttaattccgtttctgaaaaacctgtcacacgctccgattttatgtctgttcttagcaac
attgagtacatcctcatcaaagcatcttatggtcagggattacagcaaagcagaatctca
aatatttccatggaggttggcaaaaaggcggacaagttgcggccgggacagaaggcggca
tcccgtttagagaagtgtctctgtcctcctggcacggctgggttctcctgtcaggactgc
gcacctggttaccacagaggggagctgccgcaaggtggtggccgaggaccccgccctctg
ctcgctccttgtgtgccctgcagttgcaacaaccacagcgatgcctgtgaccccgaaact
ggcaggtgcctgaactgcagccatagcaccactggtgaccactgtgacttgtgtgctcct
gggtacttcgggaaggtgactggctcagccagcgactgctccgtgtgcgcctgtcctcgc
agccaccctgccagttttagtcccacttgtgtcttggaaggtgatcacgatttccgctgt
gatgcctgcattctgggctacgaaggacagtactgcgaaaggtgctcctcaggctatcac
gggaaccctcgagcgctgggtggcacttgccagcggtgtgactgcagccccagtggctct
gtccacggtgactgtgaccgcaggtccgggcagtgtgtctgcaggccgggcgccacaggg
ctccgatgcgaggaatgtgaaccgaggcacattctgctggaaagcgattgtgtttcttgt
gatgatgaatgtgtgggtgtgctgctaaatgacttagataatattggggacgccatcctt
tccgtgaacctcactggcgttatccctgtcccatctggaattttgtcaaacctggaaaat
acaacgaaatatctccgggaagctttattaaaagaaaatacacgtaaggacctggcagaa
gatcagcttgaagatgttgcaaaacaaacagaccacctgctaagggagctcactagagtg
ctaacgagtagccaacatgtaaccagggcgactgaaggaatccttgacaagagccaagac
ctcatgacatttactgagaagctgcagagaactatccaagagattattgaaaaagcagcc
actctaaatcagaccttggatgaagacttccaactacccagttctactcttcagaatatg
caaaagaatattacatctttgctagaagtcatacagaaaaggcatttcgtgcagttgcaa
cagaaagccatgctggaactcaaggctgctgaagatttattgtcacagattcagaaaaat
taccagaagccacagaaagagttggaggtattaaaagaagcagcaagcagccttctttca
aaacgcagcagtgaactgcaggcagcgagggaccttgtgagggaagcagaggtgaagaac
caggagagcgaccgcctgttgcacatcgtcagcgccaacctgcgagaatttaacgataag
acggtgcgtgttcaacaagagcaaaacttgacctccacgctgattgccagagggagaaga
ttgctagacgctgtcactgcacctgcagatgctgtaggagatgctctagcacagttagag
cgtcaccgagatgagctacttttatggactgccaaaatcaggcgccatgtagatgatctg
gtcatgcagatgtcccaaaggagagctcttgaccttgtctacagagcagaggaccacgca
gctgaactccagagactagcaggtgctctggacagtggccttggcagtgttagacatgtg
tccctgaatgccaccagtgcaacccacgtccattccaacattcggagcatgattgaagaa
tcagagaaagtggcaaaagatgctctcaagatcgtgacaacggcgagtctgttctcagaa
tcccttgctcccaatgggaaagtggctctccagcgcagttccagatttctaaaagaaggc
agcagcctgagcagaaagcatcaaggtatcacattggaactgagtaaatggaaaaataca
gcaaagagatttcaagagaatgctcatacaattactaggcggaccaatgaatcactctcc
atccttagagcattccctgaaggtgtcagagacaaaggagccaaaatcaaagagctggcc
tcatctgcaaatcggagcgctgcaagcaccctaaagaaggttgtgggattgagcaaggag
ctgttgaatacatcaactggcttgtccagggttaatgccgccttacaagaaacaaacaaa
cttctgcaggactcttcaatgaccactctgctagctggaagaagagttaaagatgcagaa
acacaagccagccttttatttgatcggttgaagcctctgaagatactagaagagaacctg
agcagaaacctatcagaaatcaaactgctgatcagccaggcccggaaacaagcagcttct
attaaagtcgctgtgtctgcagacagagattgtgtccgggcctaccagcctcagatttct
tctactaactataacaccttaacactaaatgttaagacaagtgaacccgataaccttctc
ttctacctcgggagcagcaccagttctgatttcctggcagtggagatgcggcgagggaag
gtggcctttctctgggatatgggctccgggtctacacggttggaatttccagacttccga
gctgacgacaacaaatggcacagtatctatgtaaccagatttggaaacattggttcattg
agtgtaaaggaaatgagtgcaacccaaaagccatcaacaaaaacaagtaaatcccctggg
acagctaaagttctggatataaacaattcaacactaatgtttgttggagggcttggagga
cagatcaagaagtctcctgctgtgaaggttactcattttaaaggctgcatgggagaggcc
ttcttgaacggacagtccatcggcctgtggaactatgttgaacgggagggcaagtgccac
ggctgcttcggaagcccccagaatgaagactcgtccttccattttgatgggagtggttat
tcggttgtggagaagacgctccgggctaccgtgactcagataattatgctttttagtacc
ttttcacccaacgggcttcttctctaccttgcttcaaatggcactaaagactttgtatcc
atcgagctggtgcgtggcagagttagagttacagttgacctgggttcagggcctcttgct
cttattacagacagacgctataacaacggaacctggtataaaatcgccttccagagaaac
cgaaagcaaggactcctagcagttattgatgcatataacaccagttataaagaaacgaag
caaggtgaaactccgggagcatcttctgacctcaatcgtctagataaagatccaatttat
gtgggtggattacctaggtcaagagttgtaaggaaaggtgtcaccagcaaaagctatgtg
ggctgtatcaaaaacctggaaatatccagatcaacctttgatttactcagaaattcctat
ggagtgagaaaaggctgtatactggagcctatccgaactgttagcttcttgaaaggtggc
tacgttgaattgtcacccaggtctttgttgccagaatcggaactgttggcaacatttgcc
accaagaacagcagtggcatcatcctggctgccctgggcaggcatggggagaagcagggt
catcggcaggcccatgggcaaccttcccagcccttcttttccatcatgctgattgaaggc
cacattgaagtgcacgttaactctggggacggagcaaacctgagaagagctgtcctgcgt
gctcccaagggcacatatggtgacgggcaagagcattccatctctctgatgaggactggg
agcattatcactgtccaaatggatgagacaaatcctgtagaaatgaagttgggcccatca
gcagaaagcaggacaataaatgtatccagcctgtacatagggggagttccagagggtgag
gggacatcagtgctcaagatgggaagatcatttcacggctgtatcaaaaacctgatcttt
aacatggaacatttggatttcacgagtgcggttggttatgaacaagtagatttggacacc
tgcttgctttcagaaaggccgaagctggctcttcatggagaggacagcgagctcccgcca
gagcctcagcctttaccaagtctagggcagtgtgctgtggacagagccccagagtacatc
cccaacgctcaccagtttggcctcatgcaaagcagccattttgtgttgcccttcaatcag
ctggctgtcagaaagaggctctcagttcagctaagtatccggacattggcctccagcggt
ctgatttactacatggctcatcagaaccaagttgattatgccacgctccagctgcatggg
ggccaccttcacttcatgtttgatcttgggaaaggcagaacaaaggtctcccaccctgca
gtgatcagtgatggcaggtggcacacggtcaagacagagcactttaaaagaaagggcttc
atgacagttgatggccaggaatcccccacggtgacagctgtgggagatggtaccatgttg
gatgtggaaggaaagctgtacctaggaggtcttccctctgagtacagagccaggaacatt
ggaaacatcacccacagtgtccccgcctgcattggggaggtgatactgaatggcaaacag
ctggacaagagcagcccagtgtctgcatttgcagtaagcaggtgctatgcagtggcccag
gaaggaacgttctttgaaggcagcggatacgcagctcttgtcaaggaaggctacaaagtc
cgatcagatgtaaatataacactggaatttcgtaccacctccgagaatggcgtcctcctg
gggatcagcagcgccaaagtagatgccatcggattagagattgtgaatggcaagatcttg
tttcatgttaacaatggagctggtcggataacagccacatataaacccaaagctacgagt
actctgtgcgatggaagatggcacacacttcaagctcagaaaagcaaacaccgcttggtt
ctgattgttgatgggaatgcagctcacgctgaaagtccacacacccagtccacctcagca
gacaccaacaatcccatttatgtgggcggctaccctgctgacgtaaagcaaaactgcctg
agcagccagacgtccttccgggggtgcttgagaaagctcactctgattaagggcccacaa
gtgcaatcctatgacttcagcagagcttttgatctacaaggagttttccctcattcctgt
cctgggtctgaaccctga
DBGET
integrated database retrieval system
