Panthera leo (lion): 122204203
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Entry
122204203 CDS
T10741
Symbol
SMAD4
Name
(RefSeq) mothers against decapentaplegic homolog 4 isoform X1
KO
K04501
mothers against decapentaplegic homolog 4
Organism
plez Panthera leo (lion)
Pathway
plez04068
FoxO signaling pathway
plez04081
Hormone signaling
plez04110
Cell cycle
plez04310
Wnt signaling pathway
plez04350
TGF-beta signaling pathway
plez04371
Apelin signaling pathway
plez04390
Hippo signaling pathway
plez04520
Adherens junction
plez04550
Signaling pathways regulating pluripotency of stem cells
plez04659
Th17 cell differentiation
plez04933
AGE-RAGE signaling pathway in diabetic complications
plez05161
Hepatitis B
plez05166
Human T-cell leukemia virus 1 infection
plez05200
Pathways in cancer
plez05210
Colorectal cancer
plez05212
Pancreatic cancer
plez05220
Chronic myeloid leukemia
plez05225
Hepatocellular carcinoma
plez05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
122204203 (SMAD4)
04350 TGF-beta signaling pathway
122204203 (SMAD4)
04390 Hippo signaling pathway
122204203 (SMAD4)
04371 Apelin signaling pathway
122204203 (SMAD4)
04068 FoxO signaling pathway
122204203 (SMAD4)
09133 Signaling molecules and interaction
04081 Hormone signaling
122204203 (SMAD4)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
122204203 (SMAD4)
09144 Cellular community - eukaryotes
04520 Adherens junction
122204203 (SMAD4)
04550 Signaling pathways regulating pluripotency of stem cells
122204203 (SMAD4)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
122204203 (SMAD4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122204203 (SMAD4)
09162 Cancer: specific types
05210 Colorectal cancer
122204203 (SMAD4)
05212 Pancreatic cancer
122204203 (SMAD4)
05225 Hepatocellular carcinoma
122204203 (SMAD4)
05226 Gastric cancer
122204203 (SMAD4)
05220 Chronic myeloid leukemia
122204203 (SMAD4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
122204203 (SMAD4)
05161 Hepatitis B
122204203 (SMAD4)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
122204203 (SMAD4)
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Gene cluster
GFIT
Motif
Pfam:
MH2
MH1
IRF-3
Motif
Other DBs
NCBI-GeneID:
122204203
NCBI-ProteinID:
XP_042767447
UniProt:
A0A8C9D646
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Position
D3:70486980..70546970
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AA seq
552 aa
AA seq
DB search
MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITA
ITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFD
LKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPPSMLVKDEYVHDFEGQPSLSTEGHSIQ
TIQHPPSNRASTETYSTPALLAPSESNATSTTNFPNIPVASTSQPASILAGSHSEGLLQI
ASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGH
YWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGD
RFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGR
APGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAP
AISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVL
HTMPIADPQPLD
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atggacaatatgtctattacaaatacaccaacaagtaatgatgcctgtctgagcattgta
catagtttgatgtgccatagacaaggtggagagagtgaaacatttgcaaagagagcaatt
gaaagtttggtaaagaagctgaaggagaaaaaagatgaactggattctttaataacagct
ataactacaaatggagctcatcctagcaaatgtgttaccatacagagaacattggatggg
aggcttcaggtggctggtcggaaaggatttcctcatgtgatatatgcccgtctctggagg
tggcctgatcttcacaaaaatgaactcaaacatgttaaatattgtcagtatgcatttgac
ttaaaatgtgatagtgtctgtgtaaatccatatcactatgaacgagttgtatcacctgga
attgatctctcaggattaacactgcagagtaatgctccaccaagtatgttggtgaaggat
gaatatgttcatgactttgaagggcagccatcattatccactgaaggtcattcaattcaa
accatccagcatccaccaagtaatcgtgcctcaacggagacatacagcaccccagctctg
ttagctccatctgagtctaatgctaccagcaccaccaactttcccaacattcctgtggct
tccacaagtcagcctgccagtatactggcaggcagccatagtgaaggattgttgcagata
gcttcagggcctcagccaggacagcagcagaatggatttactggtcagccagctacttac
catcataacagcactaccacctggactggaagtaggactgcaccatacacacctaatttg
cctcaccaccaaaacggccatcttcagcaccacccgcctatgccgccccatcccggacat
tactggccagttcacaatgagcttgcattccagcctcccatttccaatcatcctgctcct
gagtattggtgttccatcgcttactttgaaatggatgttcaagttggagagacatttaag
gttccttcaagctgccctattgttactgttgatggatatgtggacccttctggaggagat
cgcttttgcttgggtcaactctcgaatgtccacaggacagaagccattgaaagagcaagg
ttgcacataggcaaaggtgtgcagctggaatgtaaaggtgaaggtgatgtttgggtcagg
tgccttagcgaccatgcagtctttgtgcagagttactacttagacagagaagcgggccgt
gcacctggagatgctgttcataagatctacccaagtgcatatataaaggtctttgatttg
cgtcagtgtcatcggcagatgcagcagcaggcggccactgctcaagctgcagccgctgcg
caggccgccgccgtggcaggaaacatccctggccctggatcagtaggtggaatagctcca
gctatcagtttgtcagccgctgccggcattggtgtcgatgaccttcgccgtttgtgcata
ctcaggatgagttttgtgaagggctggggaccggattacccaagacagagcatcaaagaa
acgccttgctggatcgagattcacttacaccgggccctccagctcttagatgaagtgctt
cataccatgccgattgctgacccacagcctttagactga
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