KEGG   Panthera leo (lion): 122204412
Entry
122204412         CDS       T10741                                 
Symbol
NANS
Name
(RefSeq) sialic acid synthase isoform X1
  KO
K05304  sialic acid synthase [EC:2.5.1.56 2.5.1.57 2.5.1.132]
Organism
plez  Panthera leo (lion)
Pathway
plez00541  Biosynthesis of various nucleotide sugars
plez01100  Metabolic pathways
plez01250  Biosynthesis of nucleotide sugars
Module
plez_M00955  CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:plez00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    122204412 (NANS)
Enzymes [BR:plez01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.56  N-acetylneuraminate synthase
     122204412 (NANS)
    2.5.1.57  N-acylneuraminate-9-phosphate synthase
     122204412 (NANS)
    2.5.1.132  3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase
     122204412 (NANS)
SSDB
Motif
Pfam: NeuB SAF
Other DBs
NCBI-GeneID: 122204412
NCBI-ProteinID: XP_042767806
UniProt: A0A8C8X449
LinkDB
Position
D4:60346616..60368453
AA seq 359 aa
MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRTAKECGADCAKFQKSELEY
KFNRKALERPYTSKHSWGKTYGEHKRHLEFSHAQYRELQRYAQEIGIFFTASGMDEMAVE
FLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFC
FLQCTSAYPLSPEDVNLCIITEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHIT
LDKTWKGSDHSASLEPGELAELVRSVRLVERAMGSPTKQLLPCEMACNEKLGKSVVAKVK
IPEGTVLTLDMLTVKVGEPKGYPPEDIFSLVGKKVLVTVEEDDTILEESVENHGKKIKS
NT seq 1080 nt   +upstreamnt  +downstreamnt
atgccactggaactggagctgtgtcccgggcgctgggtgggcgggcagcacccgtgcttc
atcattgccgagatcggccagaaccaccagggcgacctggacgtggccaagcgcatgatc
cgcacggccaaggagtgtggggccgattgtgccaagttccagaagagtgagctggagtac
aagtttaatcggaaagccttggagaggccctacacgtcgaagcattcctggggaaagacg
tatggggagcacaagcgccacctggagttcagccatgcccagtacagggagctgcagaga
tatgcccaggagattggcatcttcttcactgcctctggaatggatgagatggcagttgaa
tttctgcatgagctgaatgttccgtttttcaaagttggatctggggacactaacaatttt
ccttatctggaaaagaccgccaaaaaaggccgcccaatggtgatctccagcgggatgcag
tcaatggacaccatgaagcaagtctatcagattgtgaagcccctcaaccccaacttctgc
ttcctccagtgtaccagtgcgtacccgctctcccccgaggacgtcaacctatgcatcatc
acggagtatcagaagctctttcctgacattcccatagggtattctggccacgaaacaggc
atagcgatatctgtggccgcagtggctctgggcgccaaggttttggagcgccacataact
ttggacaagacctggaaggggagtgaccactctgcctcgctggagcctggagagctggcc
gagctggtgcggtccgtgcgccttgtggaaagggccatgggctccccgaccaagcagctg
ctgccctgtgagatggcctgcaacgagaagctgggcaagtccgtggtggccaaagtgaaa
attccagaaggcactgttctaacgttggacatgcttactgtgaaggtgggtgagcccaaa
ggctaccctcctgaagacatctttagtctggtgggcaagaaggtcctggtcactgttgaa
gaagatgacaccatcctggaagaatcggtagaaaatcatggcaaaaaaatcaagtcttaa

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