Panthera leo (lion): 122204463
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Entry
122204463 CDS
T10741
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2 isoform X1
KO
K05730
guanine nucleotide exchange factor VAV
Organism
plez Panthera leo (lion)
Pathway
plez04015
Rap1 signaling pathway
plez04024
cAMP signaling pathway
plez04062
Chemokine signaling pathway
plez04510
Focal adhesion
plez04517
IgSF CAM signaling
plez04650
Natural killer cell mediated cytotoxicity
plez04660
T cell receptor signaling pathway
plez04662
B cell receptor signaling pathway
plez04664
Fc epsilon RI signaling pathway
plez04666
Fc gamma R-mediated phagocytosis
plez04670
Leukocyte transendothelial migration
plez04810
Regulation of actin cytoskeleton
plez05135
Yersinia infection
plez05205
Proteoglycans in cancer
plez05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
122204463 (VAV2)
04024 cAMP signaling pathway
122204463 (VAV2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
122204463 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
122204463 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
122204463 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
122204463 (VAV2)
04660 T cell receptor signaling pathway
122204463 (VAV2)
04662 B cell receptor signaling pathway
122204463 (VAV2)
04664 Fc epsilon RI signaling pathway
122204463 (VAV2)
04666 Fc gamma R-mediated phagocytosis
122204463 (VAV2)
04670 Leukocyte transendothelial migration
122204463 (VAV2)
04062 Chemokine signaling pathway
122204463 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
122204463 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
122204463 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122204463 (VAV2)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
SH3_2
CAMSAP_CH
CH
SH3_1
SH3_9
SH2
PH
SOS1_NGEF_PH
C1_1
DUF7145
RHG20_PH
SH2_2
PLU-1
CDC24
C1_2
DH_Alsin
PH_10
zf-RING-like
Motif
Other DBs
NCBI-GeneID:
122204463
NCBI-ProteinID:
XP_042767901
UniProt:
A0A8C8Y2I6
LinkDB
All DBs
Position
D4:91424855..91590921
Genome browser
AA seq
868 aa
AA seq
DB search
MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDI
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHHV
AQNKGIRPFPSEETAENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIKVEV
QQPMKMGMSEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMAPLRPVLSPADMTAIFINLE
DLIKVHHSFLRAIDVSMMAGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASRE
DFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSADRPERQQLKEALEA
MQDLAMYINEVKRDKETLKKISEFQSCIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDR
YLFLFDKVVIVCKRRGYSYELKEVIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGKQGF
QFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACRMFLRGTFYQ
GYLCTKCGVGAHKECLEVTPPCKISSPADLDASGAGPGPKMVAVQNYHGNPAPPGKPVLT
FQTGDVIELLRGDPESQWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPVSRPPSREIDYTE
YPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDSWIH
ITEAKKFESLLELVEYYQCHSLKESFRQLDTTLKYPYKSRERAASRASSRSPASCASYNF
SFLSPQGLSFASQGSSAPFWSVFTPRVVGTAVARYNFAARDMRELSLREGDLVKIYSRIG
GDQGWWKGEANGRIGWFPSTYVEEEGIQ
NT seq
2607 nt
NT seq
+upstream
nt +downstream
nt
atggagcagtggcggcagtgcggccgctggctcatcgactgcaaggtcctgccgcccaac
caccgggtcgtgtggccctcggcggtggtcttcgacctggcgcaggcgctgcgcgacggc
gtcctcctgtgccagctgctgcacaacctgtcccccggctccatcgacctcaaggacatc
aacttccggccgcagatgtcccagttcctgtgtttaaagaacatccgcaccttcttgaaa
gtctgccatgataaattcggactccggaacagcgagctgtttgaccccttcgacctcttc
gatgtccgagactttgggaaggtcatctctgccgtgtccagactctccctgcaccacgtg
gcccagaacaaagggatcaggccctttccctcggaggagaccgcggaaaacgacgacgat
gtctatcgcagcctggaggagctggcggacgagcatgacctgggggaagacatctatgac
tgtgtcccgtgcgaagatgagggcgacgacatctacgaggacatcatcaaggtggaggta
cagcagcccatgaagatgggcatgtccgaggacgacaagagaaactgctgcctgctggag
attcaggagaccgaggccaagtactaccggaccctggaggacattgagaagaactacatg
gccccgctgaggccggtgctgagcccggcagacatgacggccatcttcatcaacctggag
gacctaatcaaagtgcatcacagcttcctgcgggccattgacgtgtccatgatggcaggg
ggcagcactctggccaaggtcttcctggacttcaaggagaggctcctgatctacggggaa
tattgcagccacatggagcacgcccagaacacgctgaaccagctcctcgccagccgggag
gacttccgacagaaggtcgaggaatgcactctgaaggtccaggacgggaagtttaagctt
caggacctgctcgtggtccccatgcagagggtgctcaagtatcacctgctcctgaaggaa
ctcctgagccactccgcggatcggcccgagaggcagcagctcaaagaagcactagaagcc
atgcaggacttggcgatgtacataaacgaagttaagcgggacaaggagaccctgaagaaa
atcagtgaatttcagagttgtatagaaaacttgcaggtgaaactggaggagttcgggagg
ccgaagattgacggggaactgaaggtccggtccatagtcaaccacacgaagcaagatagg
tacttgttcctgtttgacaaggtggtcatcgtctgcaagaggaggggctacagctatgag
ctgaaggaggtcatcgagctgctcttccacaagatgaccgacgaccccatgaacaacaag
gacgtcaagaagtggtcctacggcttctatctaatccacctccaaggaaagcagggcttc
cagtttttctgcaagacagaggacatgaagcggaaatggatggaacagtttgagatggcc
atgtcaaacatcaagccagacaaagccaatgccaaccaccacagcttccagatgtacact
tttgacaagaccaccaactgcaaagcctgcaggatgttcctcaggggtaccttctaccag
gggtacctgtgcaccaagtgtggtgtcggggcacacaaggaatgtctggaagtgacgcct
ccctgcaagatcagttctcctgcggacctggacgcctctggagcaggaccgggtcccaag
atggtggccgtgcagaattaccatggcaaccctgctccccctgggaagccagtgctgacc
ttccagacgggtgatgtgatcgagctgctgaggggcgaccccgagtctcaatggtgggag
ggtcggctggtgcagaccagaaagtcaggctactttcctagctcgtccgtgaagccctgc
cccgtggatggaaggccgcccgtcagccgaccgccctcccgggagatcgactacacggag
tacccctggttcgcaggcaacatggagagacagcagacagacaacctgctgaaatcgcac
gccagcgggacctacctgatcagggagcggccggccgaggcggagcgctttgccatcagc
atcaagttcaatgatgaagtgaagcacatcaaggtggtggagaaagacagctggatccac
attacagaagcgaagaagtttgaaagcctcttggagctggtggagtactatcagtgccac
tcgctcaaggagagcttcaggcagctggataccacgctcaagtacccctacaagtcgcgg
gagcgcgcggcctccagggcctccagccggtccccagcttcctgcgcctcctacaacttt
tcttttctcagtcctcagggcctcagctttgcctcccagggctcctccgctcccttctgg
tcagtgttcacaccccgcgtcgtcggcacggccgtggccaggtacaactttgctgcccgg
gatatgcgtgagctctcgctgcgggaaggcgacctggtgaagatatatagccgcattggc
ggggaccagggctggtggaagggcgaggccaacggacggatcggctggtttccttcaacg
tatgtagaagaggagggcatccagtga
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