Panthera leo (lion): 122204770
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Entry
122204770 CDS
T10741
Symbol
C5
Name
(RefSeq) complement C5
KO
K03994
complement component 5
Organism
plez Panthera leo (lion)
Pathway
plez04080
Neuroactive ligand-receptor interaction
plez04610
Complement and coagulation cascades
plez04613
Neutrophil extracellular trap formation
plez04810
Regulation of actin cytoskeleton
plez04936
Alcoholic liver disease
plez05020
Prion disease
plez05133
Pertussis
plez05150
Staphylococcus aureus infection
plez05168
Herpes simplex virus 1 infection
plez05171
Coronavirus disease - COVID-19
plez05322
Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
122204770 (C5)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
122204770 (C5)
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
122204770 (C5)
04613 Neutrophil extracellular trap formation
122204770 (C5)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
122204770 (C5)
05168 Herpes simplex virus 1 infection
122204770 (C5)
09171 Infectious disease: bacterial
05133 Pertussis
122204770 (C5)
05150 Staphylococcus aureus infection
122204770 (C5)
09163 Immune disease
05322 Systemic lupus erythematosus
122204770 (C5)
09164 Neurodegenerative disease
05020 Prion disease
122204770 (C5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122204770 (C5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
plez01002
]
122204770 (C5)
Peptidases and inhibitors [BR:
plez01002
]
Peptidase inhibitors
Family I39: alpha2M family
122204770 (C5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TED_complement
A2M_BRD
C5_CUB
MG1
NTR
A2M
A2M_recep
MG4
MG2
MG3
ANATO
Prenyltrans
C3_CUB2
Motif
Other DBs
NCBI-GeneID:
122204770
NCBI-ProteinID:
XP_042768389
LinkDB
All DBs
Position
D4:complement(79873336..79958952)
Genome browser
AA seq
1680 aa
AA seq
DB search
MGLWGILVFLIFLGKSWGQEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISLKSYP
DKKFSYSSGYVTLSMENKFQNSAVLTVQPKQLSGGQNPVSHVYLEVVSKHFSRSKKVPIT
YDNGFLFIHTDKPVYTPQQSVKVRVYSLNDDLKPAKRETVLTYIDPEGSEVDIMEENDYT
GIISFPDFKIPSNPKYGVWTIRAKYKEDFSTTATAYFEIKEYVLPHFSVSIEPENSFIGY
KDFNDFEITIKARYFYNKVVNEAEVYVTFGIRDDLKDDQKEMMQEAMQNTMLINGIAQVT
FNSKMATKELSYESLEDLNNKYLYIGVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATP
LFMKPGIPYSIKVQVKDSFDQLVGGVPVTLSAQTVDVNQEMSNLESKKSVTRSSDGVASF
MVNLPSGARMLEFNVKTDDPALPEENQAGKVYQAIAYSSLSQSYLYIDWTGNYKPLLVGE
YLNIIVTPRSPYINKISHYNYLILSKGKIVHFGTREKLPDSSYQNINIPVTQNMVPSARL
LVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPSADASYSPSQHVSLNMATESNSW
VALSAVDSAIYGVQRRAKKPLERVFQVLETSDLGCGAGGGRNNADVFHLAGLLFLTNANV
DDTREDDKPCKEILRPKRMLEKKIEEKVAKYKYTLFKKCCLDGAYRNDDEDCEQRAARIT
LGPRCIRIFKECCLIAKQHRDEDLSKNIRLGRLHIKTLLPVSKPEIRSYFPESWLWEVHH
VPRRSRLQFVLPDSLTTWEIQGVGISNSGICVADTLKAQVFKDVFLEVNIPYSVVRGEQI
QLKGTVYNYRMSGMQFCVKMSTVEGICTSGSQAIGHQGINPSKCLSQRVEGSSSHLVTFS
VLPLEIGLHNINFSLETSLGKEILVKTLRVVPEGVKKESYAGVTLDPRGIYGVVSRRKEF
PYRIPLDLVPKTKVKRIVSVKGLLIGEVMSTVLSQEGIDILTHLPKGNAEAELMSIVPVF
YVFHYLEAGKNWNIFSTNSLIQNQNLRKKLKEGMVSIMSYRNADSSYSMWKGGSASTWLT
AFALRVLGQLNKYIEQNRNSICNTLLWLVENCQLENGSFKENSGYQPIKLQGTLPVEARE
NTLYLTAFAVIGIRKAFDICSLVKINTAITKADTFLLENTLSAQSTFTLAIAAYALSLGD
KTHPQFRSIVSALKKKALVKGDPVIYRFWKDDLQQESTSTPNPSTAHVVETTAYALLTSL
SLKDINYVNPIIRWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLIKQLHLNMDINVSYKH
KGDLHRYKMTETNFLGRPIEVPLNDDLVVSTGYSNGVATVHVTTVVQKTSTSEEICSFHL
KIEAQDIEASSYRRYSDSDYKRIVACASYKPSKEESSSGSSHAVMDISLPTGIGANQEDL
KALVERVDQLLADYQIKDGHIILQLNSIPSDEFLCVRFRIFELFQVGFLNPATFTVYEYH
RPDKQCTMFYNPFDARLQKVCEGVTCKCIEADCGQMQTELDLTISADARKETACKPDIAY
AYKVRITSITKENVFVKYTATLLDIYKAGEAVAQKDSDVTFIKKATCANADLEKGRQYLI
MGKEALQIKYNFSFKYLYPLDSSTWIEYWPTNAMCPSCQAFLANLDEFAEDIFLNGCENP
NT seq
5043 nt
NT seq
+upstream
nt +downstream
nt
atgggcctttggggcatacttgtttttttaatcttcctgggtaaaagttggggacaggaa
caaacgtatgtcatttcagcgccaaaaatattccgtgttggagcatctgaaaatattgta
attcaagtttatggatacaccgaagcatttgatgcaacaatctctcttaaaagttatcct
gataaaaaatttagttactcttcaggctatgttactttatccatggagaataaattccaa
aactctgcagtcttaacagtacaacccaaacagttgtctggaggacagaacccagtttca
catgtgtatttggaagttgtatcgaagcatttttcaagatcaaaaaaagtgccaataacc
tatgacaatggatttctcttcattcatacagacaagcctgtttacactccacaacagtca
gtaaaggttagagtttattcactgaatgatgacctgaaaccagccaaaagagaaactgtc
ttaacttacatcgatcctgaaggatcggaagtggacattatggaagaaaatgattatacc
ggaatcatctcttttcctgacttcaagattccatccaatcctaaatacggtgtgtggaca
atccgagctaaatataaagaggacttttcaacgactgcaaccgcatattttgagattaaa
gaatatgtgttgccacatttttctgtctcaatagaaccagaaaatagtttcattggctat
aaggacttcaatgattttgaaattactataaaagcaagatatttttataataaagtcgtc
aatgaggctgaagtttatgtcactttcggaataagagacgacttaaaagatgatcaaaaa
gaaatgatgcaagaagccatgcaaaacacaatgttgatcaatggaattgctcaagtcaca
tttaactctaaaatggcaaccaaggaactgtcctatgaaagtctggaagatttaaacaac
aagtacctttatattggtgtcacagtcatagagtctacaggtggattttctgaagaggca
gaaattcctggcatcaaatatgtcctctctccctacaaactgaatttggttgctactcct
cttttcatgaagcccgggattccgtattctatcaaggtgcaggttaaggattcatttgac
caattggtaggaggggtcccggtgaccctgagcgcacaaacggtcgatgtaaaccaagag
atgtctaacttggagtcgaagaaaagtgtaacacgttccagtgatggagtagcttcgttt
atggttaatcttccatctggagcaaggatgttggagtttaacgtcaagactgatgaccca
gctcttccggaagaaaatcaagctggcaaagtttaccaagcaatagcatattcatctctc
agccaaagttacctttatattgactggactggaaactataaacctttgcttgtgggagaa
tatctgaatattattgttacccccagaagtccatatattaacaaaatatctcactataat
tacttgattttatctaagggcaaaattgtccactttggcacaagagagaaacttccagat
tcatcctatcaaaacataaacattccagtgacacaaaacatggttccttcagcccgtctc
ctggtctattacatcgtcacaggagagcagacagcagagttggtgtctgattcagtctgg
ttaaatatcgaagaaaagtgtggcaatcagctccaggttcatctgtctccaagtgcagat
gcatcatattctccaagccaacatgtatctcttaatatggcaactgagtcaaattcctgg
gtggctttatcagcagtggacagtgctatatatggagtccagagaagagccaagaaacct
ctggaaagagtatttcaagtcttagagacgagcgacctgggctgtggggcaggtggtggc
cgcaacaatgcagatgtattccatctggctggactcctctttctcaccaacgcaaatgta
gatgacacccgagaagatgataagccctgcaaagaaattctcaggccaaagagaatgctg
gaaaagaaaatagaggagaaagttgctaaatacaaatacacactattcaagaaatgttgc
ctcgacggagcctaccgtaacgacgatgaggactgtgagcagcgtgctgcccgcattaca
ctaggtcccagatgcatcaggatcttcaaggaatgttgtcttatagcaaagcagcaccgt
gatgaggatcttagtaaaaacatccggctgggaaggctgcatataaagaccctgttacca
gtgagcaagccagaaataaggagctattttccagaaagctggttatgggaagttcatcat
gtccccagaagaagccgattgcagtttgtgctacctgattctctaactacctgggaaatt
caaggtgttggcatttcaaatagtggtatatgtgttgctgatactctcaaggcacaggtg
ttcaaagatgtcttcctggaagtgaatataccatattctgttgtgcgaggggagcagatc
cagttgaaaggaactgtttacaactatagaatgtctggtatgcagttctgtgttaaaatg
tctaccgtggagggaatctgtacatccggaagccaagccattggccaccagggcataaat
ccctccaaatgtctgtcccagagagtagaaggttcctccagtcatttggtgaccttcagc
gtgcttcccctggaaatcggcctccacaacatcaacttttcactggagacttcacttgga
aaagaaatcttagtaaaaacattacgagtggtgccagaaggtgtcaaaaaggaaagttat
gctggtgttactctggacccaaggggtatttatggtgtcgttagtagacgaaaagagttc
ccatacaggataccgttagatttggtccccaaaacaaaagtcaaaaggatcgtgagcgta
aaaggactgcttataggagaggtcatgtctacagttctgagtcaggaaggcattgacatt
cttacccacctccccaaggggaatgcagaagcagaactgatgagcattgtcccagtattc
tatgtttttcactacctggaagcaggaaaaaattggaacattttttctactaattcactt
attcaaaaccagaacctgaggaaaaaattaaaagaagggatggtgagcatcatgtcctac
agaaatgctgactcttcttacagcatgtggaagggtggcagtgctagcacttggttaaca
gcctttgctttaagagtgcttggacaattaaataaatacatagaacagaaccgaaattca
atttgtaatactttattgtggctggtggagaattgtcaactagaaaatggatctttcaag
gagaattcgggctatcaaccaataaaattacagggtaccttgcctgtcgaagcccgggag
aacaccttatatctgacagcctttgctgtgattggaattagaaaggcttttgatatatgc
tccctggtgaaaatcaacacggctatcactaaagctgacacctttctgcttgaaaatacc
ctctcagcccagagcacctttacactggccattgctgcttacgctctttccctgggagat
aaaacccacccacaatttcgttcaattgtctcagccctgaagaagaaagctttggttaaa
ggcgatccagtcatttatcgcttctggaaagacgatcttcaacaggaaagcacatccaca
cctaaccccagtacagcacacgtggtagaaaccactgcctacgctttactcaccagtctg
agcttgaaagacataaattacgttaacccaatcatcagatggctatctgaagagcagagg
tacggaggcggcttttattcaacccaggatacgattaatgccatcgagggcctgacggaa
tattcactcctgataaaacaactccacttgaacatggacatcaatgtctcttacaagcat
aaaggtgacctccaccgttataagatgacagagacgaatttccttgggaggccaatagag
gtgcccctcaatgatgacctcgtcgtcagtactgggtatagcaatggcgtggctacggtg
cacgtaacaaccgtggttcagaaaaccagtacttctgaggaaatctgcagctttcatttg
aaaattgaagcccaagacatagaagcttccagctacagacgctacagcgactcagattac
aaacgcatagtagcatgtgccagctacaagcccagcaaagaagaatcatcatcgggatct
tcccatgcagtgatggatatctctttgcctactggaatcggtgcaaaccaggaagactta
aaagctcttgtggaaagggtggaccaactattagctgattaccaaatcaaagatggacat
attattctgcaactgaattcgattccttctgatgagttcctttgtgttcggttccggata
tttgagctgtttcaagttgggtttctgaatcctgctactttcacggtgtatgaataccac
agaccagataagcagtgcaccatgttctataacccattcgatgccagactgcagaaagtc
tgtgaaggagtaacatgcaaatgcatagaagctgactgcggacagatgcagacagaattg
gatctgacaatctctgcagatgctagaaaagaaacagcctgtaaaccagacattgcctat
gcttataaagttcgtatcacatccatcaccaaagaaaatgtctttgttaagtacacggca
accctcctggatatctacaaagctggagaagctgttgcccagaaagactctgacgtcacc
ttcattaaaaaggcaacgtgtgctaacgctgatctggaaaaaggaagacaatatttgatt
atgggtaaagaagccctccagataaaatacaatttcagtttcaagtacctctaccctttg
gattcgtccacctggattgaatattggcctacaaacgcaatgtgcccatcatgccaggca
ttcttggctaatttagatgagtttgctgaagacatttttctaaatggctgcgaaaacccc
tga
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