KEGG   Panthera leo (lion): 122204813
Entry
122204813         CDS       T10741                                 
Name
(RefSeq) procathepsin L-like
  KO
K01365  cathepsin L [EC:3.4.22.15]
Organism
plez  Panthera leo (lion)
Pathway
plez04140  Autophagy - animal
plez04142  Lysosome
plez04145  Phagosome
plez04210  Apoptosis
plez04612  Antigen processing and presentation
plez05205  Proteoglycans in cancer
plez05323  Rheumatoid arthritis
plez05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:plez00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    122204813
   04142 Lysosome
    122204813
   04140 Autophagy - animal
    122204813
  09143 Cell growth and death
   04210 Apoptosis
    122204813
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    122204813
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    122204813
  09163 Immune disease
   05323 Rheumatoid arthritis
    122204813
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    122204813
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:plez01002]
    122204813
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:plez03110]
    122204813
  09183 Protein families: signaling and cellular processes
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:plez00537]
    122204813
Enzymes [BR:plez01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.15  cathepsin L
     122204813
Peptidases and inhibitors [BR:plez01002]
 Cysteine peptidases
  Family C1: papain family
   122204813
Chaperones and folding catalysts [BR:plez03110]
 Intramolecular chaperones
  Papain family
   122204813
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:plez00537]
 Others
  122204813
SSDB
Motif
Pfam: Peptidase_C1 Inhibitor_I29 Peptidase_C1_2 Styelin
Other DBs
NCBI-GeneID: 122204813
NCBI-ProteinID: XP_042768457
UniProt: A0A8C9D5G0
LinkDB
Position
D4:28158110..28162021
AA seq 335 aa
MHPSPSLFLAALCLGIASAAPQLNQSLDELWSQWKATHRKLYGMNEEGWRRAVWGENMKM
IEQHNREYKQKEHSFTMAMNGFGDMTNEEFRQVMNGLQIQKHKKGKVFQPPLFAEIPSSV
NWRKKGYVTPTKNQGQCASGWAFSATGAIEGQMFGKTHKLVSLSEQNLLDCAWSEGNGGC
SGGNMDNAFQYVKDNGGLDSEESYPYHAQLQSCKYNPENSAADITGFLTIPKTEYKLMRS
VAIVGPVSAAIDASLDTFRFYDQGIYYDSNCSHEILHHGVLIVGYGFEGAELDNKKYWIV
KNSWGEAWGIDGYILMAKDRDNHCGIASLASFPTV
NT seq 1008 nt   +upstreamnt  +downstreamnt
atgcatccttctccttctctcttcctggctgccctttgcttgggaatagcctcagctgct
ccgcaactcaaccagagcttagatgaactatggtcccagtggaaggcaacacacaggaag
ctatatggcatgaatgaagaaggatggaggagagcagtgtggggggaaaatatgaagatg
attgaacagcacaatcgggaatacaaacaaaaggaacacagcttcacgatggcaatgaat
ggctttggtgacatgaccaatgaagaattcaggcaggtgatgaatggtcttcaaatccag
aagcacaagaaggggaaagtgttccaaccacctctctttgctgagatcccctcatctgtg
aactggagaaagaaaggctacgtaactcccacaaagaatcagggtcagtgtgcttctggc
tgggcttttagtgcaactggtgccatcgaaggacagatgtttgggaaaactcacaaactt
gtttcactgagtgagcagaacctgctggactgtgcttggtctgaaggcaatgggggctgc
agtgggggcaacatggataatgccttccagtatgttaaggacaatggaggcctggactca
gaggaatcctatccataccatgcacagctccaatcttgcaaatacaatccagaaaattct
gctgccgacataactgggttcttgacaatccctaagacggagtacaaacttatgaggtca
gtggcaattgtgggtcccgtctctgctgctatagatgcaagcctggataccttccggttc
tatgaccaaggcatttattatgattcaaactgcagccatgaaatcctacaccacggcgtt
ctgatagttggctatggctttgagggagcagagttggataacaaaaagtattggattgtc
aagaacagctggggagaagcctggggcatagatggctatatactgatggccaaagaccgg
gacaaccactgtggtatcgcctccttggccagctttcctactgtgtga

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