Panthera leo (lion): 122205423
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Entry
122205423 CDS
T10741
Symbol
PIP5K1B
Name
(RefSeq) phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1
KO
K00889
1-phosphatidylinositol-4-phosphate 5-kinase [EC:
2.7.1.68
]
Organism
plez Panthera leo (lion)
Pathway
plez00562
Inositol phosphate metabolism
plez01100
Metabolic pathways
plez04070
Phosphatidylinositol signaling system
plez04072
Phospholipase D signaling pathway
plez04144
Endocytosis
plez04510
Focal adhesion
plez04666
Fc gamma R-mediated phagocytosis
plez04810
Regulation of actin cytoskeleton
plez05135
Yersinia infection
plez05231
Choline metabolism in cancer
Module
plez_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
122205423 (PIP5K1B)
09130 Environmental Information Processing
09132 Signal transduction
04070 Phosphatidylinositol signaling system
122205423 (PIP5K1B)
04072 Phospholipase D signaling pathway
122205423 (PIP5K1B)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122205423 (PIP5K1B)
09144 Cellular community - eukaryotes
04510 Focal adhesion
122205423 (PIP5K1B)
09142 Cell motility
04810 Regulation of actin cytoskeleton
122205423 (PIP5K1B)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
122205423 (PIP5K1B)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
122205423 (PIP5K1B)
09171 Infectious disease: bacterial
05135 Yersinia infection
122205423 (PIP5K1B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
plez04131
]
122205423 (PIP5K1B)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.68 1-phosphatidylinositol-4-phosphate 5-kinase
122205423 (PIP5K1B)
Membrane trafficking [BR:
plez04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
122205423 (PIP5K1B)
Endocytosis
Clathrin-mediated endocytosis
LDLR adaptor proteins
122205423 (PIP5K1B)
Endosome - Golgi transport
Others
Others
122205423 (PIP5K1B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PIP5K
Motif
Other DBs
NCBI-GeneID:
122205423
NCBI-ProteinID:
XP_042769741
LinkDB
All DBs
Position
D4:11379405..11690515
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AA seq
602 aa
AA seq
DB search
MLLQMQDHLHFYGGVIFHCAHHVALTRSSVDGYLSCFHLLTFVNNAAINTGMSSAAENGD
AASGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPDRDVLMQDFYVVESVFLPSEG
SNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFV
TSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMN
NVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALM
KTLQRDCRVLESFKIMDYSLLLGIHILDHSLKEKEEENSQNVPDAKRSGMQKVLYSTAME
SIQGPGKPGDGIITENPDTMGGIPAKSHKGEKLLLFMGIIDILQSYRLMKKLEHSWKALV
YDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKATSQEIVSSIS
QEWKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVNEH
CPHDRTMLYSNSKGLPSSSTFTLEEGTIYLTSESNALEMQDDNASVLDVYLKLQNVCFAK
MR
NT seq
1809 nt
NT seq
+upstream
nt +downstream
nt
atgttgttgcaaatgcaagatcaccttcatttttatggcggagtaatattccattgtgca
caccacgtcgccctcacccgttcttctgtcgacggatacttgagttgtttccacctcttg
acttttgtaaataatgcggcaataaacacggggatgtcgtctgctgctgaaaatggagat
gcagcatctggaaaacagaacgaagaaaaaacttacaaaaagactgcatcatctgctatc
aaaggtgctattcagctggggataggatacaccgtgggcaatctcacttcgaagccggat
agagatgttctcatgcaagacttttacgtggtggaaagtgtgttcctacccagtgaaggg
agcaatctgaccccagcacatcattacccagacttcagatttaagacctatgctccactg
gcattccgatatttcagagaacttttcggtatcaagcctgatgattacttgtattccatc
tgtagtgaacctctaatagagctgtccaaccccggagccagtggatccttgttttttgtg
accagcgatgatgaatttatcatcaaaaccgttcagcataaagaagctgagttccttcag
aagctactgccaggctattacatgaatttgaaccagaatccgaggactcttttgccaaaa
ttttacggactgtactgcatgcaatcggggggcattaacatcaggatcgtggtaatgaac
aacgtcttaccgcgctccatgagaatgcacttcacatatgacctgaaaggctccacgtac
aagcgaagagcttcccgaaaagagagggagaaatccaaccccaccttcaaggacttggat
ttcctgcaggacatgcacgaaggcttatattttgacacagaaacttacaacgcgctcatg
aaaacacttcagagagactgccgggtgctggaaagcttcaaaatcatggactatagcctt
ttgctgggaatccacatcctggaccattccctcaaagagaaagaagaggagaactcacaa
aacgtgcctgatgctaaacggtcggggatgcagaaggtcctctattcgacagcaatggaa
tccatccagggtccagggaaaccaggagacgggatcatcacagagaacccggacacaatg
ggaggcattccagctaaaagccataagggagaaaaactacttttgtttatgggcattatt
gacattctgcaatcatataggttaatgaagaagttagaacattcctggaaagcgcttgtt
tatgatggggatactgtttcagttcatcgaccaagcttttatgctgacagatttctaaag
tttatgaattccagagttttcaagaaaattcaagctttgaaggcctcaccttctaaaaaa
cggtgcaactccatcgctgccctgaaggcaacctcccaagagatcgtgtcctcaattagc
caggaatggaaggatgagaagcgggatctgctgaccgaggggcagagtttcagcagcctt
gatgaggaagccctgggatcccgacacaggccggacctggtacctagcactccttcactc
tttgaagctgcttccttggcaaccacgatttcttcttcttccttatatgtcaatgaacat
tgtccgcacgacaggactatgctctattcaaacagtaaagggttaccttccagttcaaca
tttaccttggaagaggggaccatctacttgacttcggagtccaatgctctggaaatgcag
gatgataatgcctctgtgcttgatgtctatttaaagcttcaaaatgtgtgttttgccaaa
atgagataa
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