Panthera leo (lion): 122205537
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Entry
122205537 CDS
T10741
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
plez Panthera leo (lion)
Pathway
plez05014
Amyotrophic lateral sclerosis
Brite
Enzymes [BR:
plez01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
122205537 (SETX)
5.6.2.5 RNA 5'-3' helicase
122205537 (SETX)
Transcription machinery [BR:
plez03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
122205537 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
122205537
NCBI-ProteinID:
XP_042769900
LinkDB
All DBs
Position
D4:complement(89706879..89771597)
Genome browser
AA seq
2669 aa
AA seq
DB search
MSTCCWCTPGGVSTADFLKRYASRTHAGEFQTADEDLCYCLECVAEYHRARDDLPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLEDPDIYTCSVLEKGKLILLPAHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQADDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEAFQTIINNMSYNREIQNIRNSSVRTKSEPESYLDDTVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGAAVISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIRNIKFKVP
QCSTFVDLTPVCKTPPASYNKEESEQTGKKSKKGLPCLENSSPTFSKGPTKAEAFQMPEN
RLVKASNASEEDSEHSYIKDLKLEGRLSAETCIKQGSKRLFPERAQDAVKTSKGKQKSVK
ENPTDSRNGPERGCDRGVIIAARSLTDSGTDSLEKASTSTEDFSFKDDVLGKTSKGKTKG
QKAEICAKLSHVIKKQHRKSTLIDDVNLEETLTVSTIDSFFSRKDSGGQKGDGFINHLSL
DPDDVPDDKNGERKSQNSLLLKKKHFKTKELDIFSSHENSCQIQERQADGKDLVSFTEMT
DTCVKKTSPFKDPVTLLESRDKEVGKSTTSQGSSHLREQVPSLSPQSNTLTDSQIDRDLH
NLSLIAQASVIKFPSESTQKSSSQLQRKVKDKRCFTANPNNAGEACRGQVIIISDSDDDD
GDEGILGFEKHIKRDKIGIKKEYPEEHTSVASTNVEQKLIKEEEAKSLLEFEESDSQFFE
FESPHEVFSVWQDQEPDNKNSVQEDENKSRLTHLNDVTNDWGYDTDYVSEEVIKKVAEGI
EKHTEPQSGGSVGEFCATEVKKRKRKRYEKPVAEDPLRPSPSERNEDQSDNERGLTGSDL
KSIELRSSSRSNLQRDTTDSLKKSSPKLRTYSKPVRRVPHSKTKKTHSDTKKGQNKSSNY
ISCRTTPAIVPPKILRQCPEPTSTVEKLGLKKAPRRAFDLSQRSLGYLVQLRDHGKTVGV
VDTRKKAKLISPQTLSVKNNKKLLTSQDLQSRRQAKHKSKQKRRGSLGSESRAPTRAGLR
SAQNPDPPVPGSDSSDYRANGGAEVGATNTGKPSIKRASSEPEPVKTKRVSQVADDPCLS
NQCASVVLNGRKPTHEAIVSTSADPLGGGDLTEHRLELTALKEGEPRSNSDSEDENIFLT
QRDPADMDLCSQMENGNEKLIEVVHGKETALTEEGSWSSTKCKYKDCVEAAQKQGEYCSK
HCEAKAVDEDVFRKPGLPPSASKRPSTAKVFSSSSTSRIANLSKSLESSSAPPPALKQKS
NGVPSVLKVPQPASVLSPKPMGEVKSLSDVLRPQTLNNFNRQGYKLTFGESRSFSASSAV
NVLLSSQSISDTFVKEVLKWKYEMFVNFDQCGPPTSLCQSISRPVPVRFQDCGDYFNVFF
PLMILNTFETVAQEWISSPNKEKFYQLHVRKFPADYKKYWEFVVHLEECELTKQLHPKEN
DLVFLVLEKQNGEKKNTERSRMPDLHEYHCGYVHKFRRTSVMRNGKSECSLSIQTQDNLP
LSLNELVKCTVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMDFCTKDLLTTTSERII
AYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKG
RSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGP
EKSINNEVLRFSLDSQVNHRMKKDLPSHVQEMHRRKEFLDHQLDELSRQRALCRGGKETQ
RQELDEKIAKVSKERQELASKIKEVQGRPQKTQSIIILESHVICCTLSTSGGLLLESAFR
GQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQS
MMARFCKLLEDSVEHNVIGRLPVLQLTVQYRMHPDICLFPSNYVYNRSLKTNRLTETNRC
SSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRRDVTFRNIGIITHY
KAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANAMQGSIGFLASLQRL
NVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIVKTCDKNYRHDAAKILKLKPV
LQRSLTHPPTVAPEVARPQGGLPSSKPDGEFAKTSFPSSLYHVPSGCKESTGTVTTKDPE
RPPIQDRLRDPRLLRRLGIDPEAKGTCPRDPQPLSPQHPGATPPSGEPGFPLSHQDLGGA
QLSTARGTTLSNQNPPVQWEPPAAGTDVSASKRACDWEGGLSRRRETRAFSEGDRETQSP
ESRHPKRRSGWDNRRLEEEASGSKKRKFL
NT seq
8010 nt
NT seq
+upstream
nt +downstream
nt
atgagcacgtgttgttggtgtacgcccggtggtgtttccaccgctgacttcctcaagcgc
tatgcgtccaggacccacgccggggagtttcagacagccgacgaagacctctgctactgc
ctggagtgtgtggccgagtaccacagagcacgcgacgacctgcccttcctgcatgaggtt
ttgtgggaattagaaaccttacgtctcataaatcattttgaaaaatccatgaaggcagaa
attggggacgatgatgaattgtacatagtagacaacaatggagaggcacagctttttgac
ttcactggccaagactttgaaaataagcttcgggttcctcttcttgaaatcctgaagtat
ccgtatctgcttttacacgagcgtgttaacgaattatgtgttgaagcactttgtcggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccaggcatttatttgtttctg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaaggaacttgggaaaa
gtggacagagatgactattatgatctgcaggaggttttgacttgtctttttaaagtcatt
gagttggggcttctggaagatccagacatctacacttgttctgtcctcgagaagggtaaa
ctgattcttctgcctgcgcacatgtacgataccaccaactacaagaactattggctaggt
atttgcatgttgctgaccattcttgaggagcaggctatggactccctgttgctgggctcg
gacaaacagaatgattttatgcaatcaatccttcacaccatggagaggcaagcagatgat
gatagcgtggatcctttctggccagcattacactgtttcatggtgattctggatcgcctc
ggatcaaaggtctggggtcaacgcatcgatcctattgaggcgtttcagaccattatcaat
aacatgagctacaatagagagatccaaaatatacggaacagctctgtaaggaccaagtca
gaaccggagtcgtatttggatgatacagtgacttgtagccagatcgtgtacaattacaac
cctgaaaagaccaaaaaggattccgggtggagatcagccatttgcccagattactgtcct
aacatgtacgaagagatggaaacgttagccagtgtgcttcagtcagatatcggtcaagac
atgcgtgttcacaatagcacgtttctgtggttcatcccctttgttcagtccctcatggat
cttaaggatttgggtgtggcttacatagtagaggtgattcaccatctgcactctgaagtc
aaagatgtcctcaaccaaacagatgctgtgtgtgacaaagttactgagtttttccttctg
attttggtgtccgtgattgaactgcacagaaataaaaaatgtttgcacttgctgtgggtt
agttcccagcagtgggtggaggctgttgtaaaatgcgccaagcttcccaccaccgcgttt
gcacggagttctgagaagtcatctggaaattgctccaaaggagcagcagtgatctcgtct
ctgtcactgcattcgatgccatctaattctgtccagctggcttgtgtgcagctgatcaga
agtctccttaaagaagggtatcagcttgggcagcagactctgtgcaagcgattctgggac
aagctcaacttgtttctgcgtgggaatttatctctgggttggcagttgactactcaggaa
acccatgagttacaaacttgtttaaagcaaattattagaaacataaaattcaaagtacct
cagtgtagcacttttgtggatctgactcccgtatgtaaaacccctcctgcgtcttacaat
aaagaagaaagtgaacagacagggaagaaatctaaaaaaggcctgccctgtctggaaaac
tccagcccaacattttctaaaggaccaacgaaagctgaagcatttcaaatgccagagaat
agattggtcaaagcaagtaacgctagcgaagaggatagtgagcacagttacataaaagat
ttgaaactagaaggccgtctctcagcagagacatgcataaagcagggtagcaaaaggctt
ttcccggaaagagctcaagatgcagttaaaacaagtaaagggaagcagaagtctgtgaag
gagaatcctacggattccagaaatggtccggaaaggggatgtgacagaggggtgataata
gccgcacgttcgttgactgattctggcaccgactccctggagaaggcgtccacatcaact
gaggatttctctttcaaggatgatgttcttggcaaaacgtcaaaaggaaaaactaaggga
cagaaagctgaaatctgtgctaagttatcacatgtaataaagaagcaacacaggaaaagt
actttgatcgatgacgtcaatttagaggaaacactgactgtgtctaccattgacagtttc
ttttcaaggaaagattcaggaggtcagaaaggggatggcttcataaaccatctctcttta
gaccctgatgacgttcccgatgataaaaacggggagcgaaaatctcaaaacagtttattg
ctgaagaagaaacacttcaagaccaaagagttagatattttctcttcccacgaaaatagc
tgtcaaatacaggaacgccaagcggatggtaaagatttggtctcgtttacggaaatgact
gatacttgtgtgaagaaaacctctcccttcaaagaccccgtgactcttcttgaatcgaga
gataaggaagttggcaagagtaccaccagtcaggggtcttctcacttgagggaacaggtt
cctagcctcagtccacagtccaacacgttgacagattcccagatagaccgagacctccac
aacttatctttgatagcccaagccagtgttattaagtttccgtcggagtcaactcaaaaa
agctcatcccagctacaaagaaaagtaaaagataaaaggtgtttcacagctaacccgaat
aatgctggagaagcctgccggggccaggtgattatcatttcagattctgatgatgatgat
ggtgacgaagggattctgggttttgagaaacacattaaacgagataaaataggcatcaag
aaagaatatccagaggagcatacttcagtagctagtacaaatgtggaacagaagctaata
aaggaagaagaggcaaagtccctattggagtttgaggaatcggattctcagttttttgag
tttgaaagtccacatgaggtgttttcagtttggcaagatcaggaaccagacaacaagaac
tcagttcaagaggatgaaaacaagtcacgtctgactcacctaaacgatgtcacgaatgat
tggggttatgatacagattatgtatctgaagaggttattaagaaagtagcagagggcatt
gaaaaacacacagaaccacagagtggtggttctgtcggggaattttgtgcaactgaagtg
aaaaaacgtaagagaaaacgatatgaaaaacctgtagctgaagatcctctgaggccttca
ccttctgagaggaatgaggaccagtctgataatgagagaggtctgactggaagtgatctt
aaaagtatagagctgaggtcaagttccaggtcgaatcttcaaagagacactacagattca
ctaaagaagtcttctccaaagcttcgtacttactccaaacccgttaggagagtcccgcat
tctaaaactaagaaaacacattcagataccaaaaaagggcagaataaaagttcgaattac
ataagctgtaggacgactcctgctatagtcccaccaaagatacttcgccagtgccctgaa
ccaacttcaactgttgaaaaacttggtctgaaaaaggctcctcgtagggcattcgattta
tctcagcgatctctagggtatttagttcagttacgggaccatggcaaaaccgtgggagtg
gttgataccagaaaaaaggctaaattaatttctcctcagactctctctgtcaaaaataat
aagaaactgttgacaagtcaagatcttcagtcgcgaaggcaggcgaaacacaaatcaaag
cagaagaggcgaggatctctgggttctgaaagtagggctcctacaagagcagggctgcgt
tcagcccagaatcctgaccctcccgtcccaggatccgatagctcagattatcgtgctaac
ggaggcgccgaggtgggtgctaccaatactggaaagccatcgataaaacgcgcgtcttcg
gaaccagaacccgtgaaaacgaaacgtgtttctcaggtggctgatgatccttgcctttcg
aaccagtgcgcttctgttgtgttaaatggaagaaaaccaacgcatgaagccattgtctct
acgtcagctgaccctttaggtggaggcgacctaacagaacatcgtttagagttgaccgct
ctgaaagagggagagcccagatccaacagtgactcggaagatgagaatatatttctaacc
cagcgcgatcccgcagatatggatttatgttcacaaatggaaaatggtaacgagaaactc
attgaagtagttcatggaaaagagacagctctgacggaagaaggatcctggagcagcaca
aaatgtaagtacaaggattgtgtcgaagccgcgcaaaagcagggtgaatactgctccaaa
cactgcgaagctaaagcggtggatgaagatgtgtttcgtaaaccgggcctgcccccctct
gcgtccaagagaccctccactgccaaggtctttagctcaagtagtacttcacgaatcgct
aatctttcgaagtctttggaaagttcctccgcaccgccaccggctctcaaacagaagtca
aacggggtaccatctgttttgaaagtcccacagccagcctctgtgttgtctccaaagcca
atgggtgaggtgaagagtttgtctgatgttctccgtcctcagaccctgaataatttcaac
aggcaaggttacaagcttacgtttggcgaaagcagatctttttcggcttcctctgcggtg
aacgttctcttgtcctcacagtctatctcggacacctttgttaaagaggtcttaaagtgg
aagtacgaaatgtttgtgaactttgatcagtgtgggccccccaccagcctttgtcagtcc
atctcaagaccggtgcctgtcagatttcaagattgtggagattatttcaatgtttttttc
cctttgatgatactgaatacttttgaaacggtggcacaggagtggatcagctctccaaac
aaagagaagttctatcagttgcacgtacggaaatttcctgctgattataaaaagtactgg
gagtttgtggttcatcttgaggaatgtgaactaactaaacagctgcatccaaaggaaaat
gatttggtgtttttggttcttgaaaaacaaaatggagagaagaagaacacagagagaagt
cgcatgccggatctccacgaatatcactgcggttatgttcataaatttcgccgcacctca
gtcatgcgtaatgggaaatctgagtgttccctttccatccagactcaagataatttgcca
ctcagtttaaatgaactcgtgaaatgcactgtaatcagttctctggtaactacacagagg
aagttgaaagccatgtctttgttgagtggacggaaccaactagccagagctgttctgaac
ccaaaccccatggacttctgtacgaaagatttactgactacgacgtctgagagaatcatc
gcctacttgaaagatttcaacgaagaccaaaagaaagcgatagaaactgcatacgccatg
gtcaaacactccccatcggttgccaagatctgtttgattcatggaccacctggaacagga
aagtcaaaaacgatcgttggcctcctgtaccgcctgctgacggagaaccagaggaagggg
cgttcagatgaaaactccaatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcacct
tccaacgcggctgttgatgaacttatgaaaaaaatcatcctcgaatttaaagagaagtgt
aaagacaagaagaatcctttggggaactgtggagatataaatttagtacgtctgggtcca
gaaaagtctattaataatgaggtcctaagatttagtttggacagccaagttaaccacaga
atgaaaaaagacttaccttctcatgttcaggagatgcatagaagaaaggaatttctagat
catcagctagatgaactttcccgccagcgtgctttatgccgaggtggaaaggaaacacag
aggcaagaattagatgaaaaaatcgcaaaggtttcaaaagagaggcaggaactagcttct
aaaattaaagaggttcaaggacgcccacaaaaaacacagagcatcatcatcttagagtcc
cacgtcatctgctgcacactgagcacgagtggcggtttactgctcgagtctgcttttcgt
gggcaagggggtgtccccttcagttgtgtcatcgtcgatgaggctgggcagtcttgtgaa
gtggagactcttaccccgctcatccatcgttgtaacaagctgatcctcgtcggagaccca
aaacagctccctcccacagtcatttccatgaaagcacaggagtatggctatgaccagtca
atgatggctcgcttctgcaagctgctggaagacagtgtagagcacaatgtgatcggcagg
ctgcctgttttacagcttactgttcagtacaggatgcacccagacatatgtctcttcccc
tctaattatgtttataacagaagcttgaaaacaaatagactgactgaaaccaatcggtgt
tcatcagactggccatttcaaccttacctcgtgtttgatgtcggagacggttcagaaaga
cgggataatgactcatatataaatgttcaagaaataaaactggtaatggaaataattaaa
cttattaaagacaaaagaagggatgttactttccggaacattggcataataacccattac
aaggctcagaagacgatgattcagaaggatttggacaaagagtttgatagaaaagggccg
gcagaagtagataccgtggacgcgttccagggccgccagaaagattgtgttatcgtcaca
tgtgtcagagcaaatgccatgcaaggctccattggatttctggcaagtttgcaaagattg
aatgtcaccattacacgagccaagtacagcctcttcatcctcggacatttaaggaccttg
atggaaaatcagcactggaatcacctgattcaggacgcacagaagcggggtgccattgtc
aagacgtgcgacaaaaactacaggcacgacgcagccaagattctgaaactcaagcccgtc
ctgcagagaagtctgactcacccgcccaccgtggccccggaggtggccagaccccagggt
ggcttgcccagcagcaagccagacggtgaatttgccaagacgtctttcccttcctccctg
tatcacgtgccttctggctgtaaggaatccactggtactgttaccaccaaggaccctgaa
agacctcctattcaggaccggcttcgggacccacgactgcttaggaggctgggcatagac
cccgaagccaaagggacatgcccgagggatccgcagcccctgagcccccagcatcctggg
gccacacctccctcgggggagccaggcttccctctgagtcaccaggacctgggtggtgcc
cagctgtccaccgccagagggaccacgctgagcaaccagaaccctcccgtgcagtgggag
cctccagctgccggtacggatgtctccgctagtaaaagagcatgtgactgggaaggaggg
ctcagccgcaggagagagaccagggctttcagcgaaggggaccgggagacgcagagcccc
gagagccgtcacccgaagaggcgctctggctgggacaacaggagactggaggaggaagcc
agtggttccaagaaaagaaagtttttatag
DBGET
integrated database retrieval system
