Panthera leo (lion): 122206566
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Entry
122206566 CDS
T10741
Symbol
ITGA2B
Name
(RefSeq) integrin alpha-IIb
KO
K06476
integrin alpha 2B
Organism
plez Panthera leo (lion)
Pathway
plez04015
Rap1 signaling pathway
plez04151
PI3K-Akt signaling pathway
plez04510
Focal adhesion
plez04512
ECM-receptor interaction
plez04611
Platelet activation
plez04613
Neutrophil extracellular trap formation
plez04640
Hematopoietic cell lineage
plez04810
Regulation of actin cytoskeleton
plez04820
Cytoskeleton in muscle cells
plez05165
Human papillomavirus infection
plez05200
Pathways in cancer
plez05222
Small cell lung cancer
plez05410
Hypertrophic cardiomyopathy
plez05412
Arrhythmogenic right ventricular cardiomyopathy
plez05414
Dilated cardiomyopathy
plez05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
122206566 (ITGA2B)
04151 PI3K-Akt signaling pathway
122206566 (ITGA2B)
09133 Signaling molecules and interaction
04512 ECM-receptor interaction
122206566 (ITGA2B)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
122206566 (ITGA2B)
09142 Cell motility
04820 Cytoskeleton in muscle cells
122206566 (ITGA2B)
04810 Regulation of actin cytoskeleton
122206566 (ITGA2B)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
122206566 (ITGA2B)
04611 Platelet activation
122206566 (ITGA2B)
04613 Neutrophil extracellular trap formation
122206566 (ITGA2B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122206566 (ITGA2B)
09162 Cancer: specific types
05222 Small cell lung cancer
122206566 (ITGA2B)
09172 Infectious disease: viral
05165 Human papillomavirus infection
122206566 (ITGA2B)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
122206566 (ITGA2B)
05410 Hypertrophic cardiomyopathy
122206566 (ITGA2B)
05412 Arrhythmogenic right ventricular cardiomyopathy
122206566 (ITGA2B)
05414 Dilated cardiomyopathy
122206566 (ITGA2B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
plez01009
]
122206566 (ITGA2B)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
plez04147
]
122206566 (ITGA2B)
04515 Cell adhesion molecules [BR:
plez04515
]
122206566 (ITGA2B)
04090 CD molecules [BR:
plez04090
]
122206566 (ITGA2B)
Protein phosphatases and associated proteins [BR:
plez01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
122206566 (ITGA2B)
Exosome [BR:
plez04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
122206566 (ITGA2B)
Cell adhesion molecules [BR:
plez04515
]
Integrins
Integrin alpha subunits
122206566 (ITGA2B)
CD molecules [BR:
plez04090
]
Proteins
122206566 (ITGA2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Integrin_A_Ig_3
Integrin_A_Ig_2
Integrin_A_Ig_1
FG-GAP
FG-GAP_3
Integrin_alpha
Motif
Other DBs
NCBI-GeneID:
122206566
NCBI-ProteinID:
XP_042771815
LinkDB
All DBs
Position
E1:complement(42101010..42115337)
Genome browser
AA seq
1037 aa
AA seq
DB search
MARAVCPLHALWLLEWVQLLLGPDAVPLAWALNLDPVQLTFYTGPNGSHFGFSLDFYKDS
RGSVAIVVGAPRTRGRSQEETGGVFLCPWRTEGGQCTSLPFDLNDETRHVGSQTFQTFKA
GQGLGASVVSWNNNIVACAPWQHWNALEKTEEAEKTPVGGCFVAQLQTGYRAEYSPCRAN
TMSRGYVTKSFIQDKRYCEAGFSSAVTQAGELVLGAPGGYFFLGLLARAPIAEIVSSYRP
GTLLWNVPTQRFSADYTNPVYFDGYRGYSVAVGEFDGDINTTEYVLGAPTWSWTLGAVEI
LNSDHQTLHRLHGEQVASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY
LFLQPRGHHPLGAPSVLLTGTQLYGRFGSAIAPLGDLDRDGYNDVAVAAPYGGPSGRGQV
LVFLGQSEGLSSRPSQILDSPFPTGSGFGFSLRGATDIDDNGYPDLLVGAYGANQVAVYR
AQPVVMANVQLLVQDSLNPAVKNCVLPQTQTPVSCFNIQMCVGVTGHSIPQKLPLQAELQ
LDRQKPRQGRRVLLLNSQQAGTTLHLDLGRRHSPICHSTMVFLRDEADFRDKLSPIVLSF
NVSLQPEKDGIAPELVLHGDTHVQKQTRIILDCGEDDLCVPQLQLTANVTGSPLLIGADN
VLELQMDAVNEGEGAYEAELVVHLPPGTHYMRAIGNTEGFERLICNQKKENETKVVLCEL
GNPMKTNAQIGITMLVSVGDLEEAGERVSFWLQIRSKNSQNPNSEAVMLDVPVRAKAHME
LQGNSFPASLLMVAEEGNGENSSDSWGPKVEHTYELHNNGPSTVSGLHLSLSFPSQSQPS
DLLYILDIQPQGGLRCSPQPAPNPLKLNWGLPTPSPSPIYTGHHKRDRRQALLPGSNQPS
RLQDPVRVSCDSVPCTVVQCELQEMARGQRAMVTVLAFLWLPSLRQRPLDQFVLKSKAWF
NVSSLPYSVPALSLPSGEFAVETQLLRVLEERDIPIWWVLLGVLGGLLLLTVLVLAMWKV
GFFKRVRPPLEEDEEEE
NT seq
3114 nt
NT seq
+upstream
nt +downstream
nt
atggccagagctgtgtgtccacttcatgccctctggcttctggagtgggtgcagctgctc
ttgggacccgatgctgtccctctagcctgggccttgaacctggacccagtgcagctcacc
ttctacacaggccccaatggcagccactttgggttttcgctggacttctacaaggacagc
cgtgggagcgtggccatcgtggtgggcgccccgaggacccggggccgcagccaggaggag
acgggcggcgtgttcctgtgcccctggaggaccgagggcggccagtgcacctcgctgccc
ttcgacctcaatgatgagacccgacacgtaggctcccaaaccttccaaactttcaaggcc
gggcaaggactgggggcgtcggtcgtcagctggaacaacaacattgtggcctgcgccccc
tggcagcactggaacgccctagaaaagacagaggaggctgagaagacgcccgtaggtggc
tgcttcgtggctcagctccaaaccggctaccgcgcggagtactcgccctgtcgggctaac
accatgagccggggttacgtgacaaagtcctttatccaagacaagcgctactgcgaagcg
ggcttcagctccgcggtcactcaggctggagagctggtgcttggggcccctggcggctat
tttttcttaggtctcctggcgcgagctcctattgccgaaatcgtctcgagttaccgccca
ggcaccctcttgtggaacgtgcccacccagcgcttctccgcagactacaccaacccagtg
tacttcgacggctaccgggggtactcggtggccgtgggcgagttcgacggggatatcaac
actacagagtatgtcttaggcgcccccacctggagctggaccctgggagcggtggaaatt
ttgaactcggaccaccagacgctgcaccggctgcacggagagcaggtggcttcgtatttc
gggcactcggtggccgtcactgatgtcaacggggacgggaggcacgacctgctggtgggc
gcgccactgtacatggagagccgcgctgaccgcaaactggccgaggtggggcgtgtgtac
ttgttcctgcagcctcgcggtcaccacccactgggcgcccccagcgttctgctgacgggc
acacagctctacgggagattcggctccgccatcgcgcctctgggcgacctcgaccgggat
ggctacaatgatgttgcagtggccgccccctacgggggtcccagtggtcggggccaagtg
ctggtgttcctgggtcagagtgaggggcttagctcacgcccctcccagatcctggacagc
cccttccccacaggctctggcttcggcttctccctgcgaggtgccacagacatcgatgac
aacggatacccagacctactggtaggagcttatggggctaaccaggtggctgtgtacaga
gctcagccagtggtgatggccaatgtgcagctgctggtgcaagattcactgaatcctgct
gtgaagaactgtgtcctgccccagacccagacaccagtgagctgctttaacatccagatg
tgtgtaggagtcactgggcacagcattcctcagaagctgcccctacaagctgagctgcag
ctggaccggcagaagcctcgccagggccggcgggtgctactgctgaattctcaacaggcg
ggcaccaccctgcatctggacctgggcaggaggcacagccccatctgccactccaccatg
gtcttcctccgggatgaggctgacttccgggacaagctgagccccatcgtactcagcttc
aatgtgtccctgcagcccgagaaggacggaatagcccccgagctcgtgcttcatggggac
acccatgtccagaagcagacccgcatcatcctggactgcggagaggatgatctgtgtgtc
ccccagctgcagctcaccgccaacgtgacgggctccccactcctcattggagccgacaat
gtgctggagctacagatggatgcagtcaatgagggagagggggcctacgaggccgagctg
gttgtgcacctgcccccaggtacccactacatgagggccatcggcaacactgagggcttt
gagagactcatctgtaaccagaagaaggagaatgagaccaaggtggtgctgtgtgagctg
ggcaacccgatgaagacaaatgcccagataggaatcacgatgttggtgagcgtgggggac
ctggaagaggctggggagcgtgtgtccttctggctgcagatcagaagcaaaaatagccag
aatccaaacagcgaggctgtgatgctggacgtaccagtccgggcaaaggcccacatggaa
ctgcaagggaactcctttccagcctccttgctgatggtggcggaagaaggcaacggggag
aacagctcggacagctggggccccaaagttgagcacacctatgagctccataacaatggc
cccagcactgtcagtggcctccacctcagccttagctttcccagccagtcccagccctct
gacctgctctacatcttggatatacagcctcagggggggcttcgctgctccccacagccg
gctcctaaccccctcaagctgaactgggggctgcctacccccagcccttcccccatttac
acggggcatcacaagcgggaccgcagacaggccctcctgccagggtccaaccagccctcc
aggcttcaggatccagttcgcgtgagctgcgactcagtgccctgtacagtggtgcagtgt
gagctacaagagatggcacgagggcagagggccatggtcacggtgctggccttcctgtgg
ctgcccagcctccggcagaggccactggatcagttcgtgctaaagtcaaaagcttggttc
aacgtctcctcccttccttactctgtgcccgccctcagcctgcccagtggagaatttgca
gtcgagacgcagctgcttcgtgtcttggaggagagagacattccaatctggtgggtgctg
ttaggcgtattgggcggcctgctgttgctcacggtcctggtcctggccatgtggaaggtt
ggcttcttcaagcgtgttcggccaccactagaagaagatgaagaggaggagtga
DBGET
integrated database retrieval system
