Panthera leo (lion): 122206743
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Entry
122206743 CDS
T10741
Symbol
PFAS
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
plez Panthera leo (lion)
Pathway
plez00230
Purine metabolism
plez01100
Metabolic pathways
Module
plez_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122206743 (PFAS)
Enzymes [BR:
plez01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
122206743 (PFAS)
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GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-GeneID:
122206743
NCBI-ProteinID:
XP_042772136
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All DBs
Position
E1:2919516..2937569
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AA seq
1336 aa
AA seq
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MPSVLHFYVRPSGHERAASGHTRRKLQGKLPELQAVKTELCYNVNWTADSLPSAEEMKKL
TWLFGCPLLPGDVAQESWLRSDSSDLLLEVGPRLNFSTPASTNVVSVCWAAGLGAVDRVE
TTRRYLLSFAKPPSSETKTLALATLHDRMTEQHFPRPIQSFSLRSMSAPLNGRIDILAEG
RRALEKANQELGLALDSWDLDFYTKRFQELKRNPSTVEAFDLAQSNSEHSRHWFFKGQLH
MDGQEMTHSLFEAIMSTQASSNPNNVLKFCDNSSAIQGKEVRFLQPEDPTRPSCFRQQRA
LRHVVFTAETHNFPTGVAPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGY
NLPWEDPSFQYPENFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREW
IKPIMFSGGIGSMEAEHVSKEPPEPGMDVVKVGGPVYRIGVGGGAASSVQVQGDNSSDLD
FGAVQRGDPEMEQKMNRVIRACVEAARGNPICSLHDQGAGGNGNVLKELSDPAGAVIYTS
RFQLGDPTLNALEIWGAEYQESNALLLRPVDRDFLSRVSARERCPACFVGTITGDRRIVL
VDDRDCPVGRNGEGDAPSPPTPVDLELDWVLGKMPRKEFFLQRSLPVLRPLALPPGLSVR
QALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHQELVGAA
TALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAALA
DACAAMVAVMAALGVAVDGGKDSLSMAARVGSETVRAPGSLVISAYAVCPDITATVTPDL
KRPGGRGRLLFVPLSPGQHRLGGTALAQCFSQLGEQPPNLDLPENLVRAFRITQGLLRDR
LLCSGHDVSDGGLVTCLLEMAFAGNCGIEVDVPAPGVDVLPTLFAEEPGLVLEVRGPDLA
QVLKRYRDAGLYCLELGATGDAGPHALVRVSVNGAVVLEESVRQLRALWEETSFQLDRLQ
AEPRCVAEEEQGLRERTGPTYCLPPGFPKASVPREPGGPVPRVAILREEGSNGDREMADG
FHSAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPLAGAE
LRRFRKRPDTFSLGVCNGCQLLALLGWVGGSPSEEAEGTGQDSLPARPGLLLRHNLSGRF
ESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYMAFSSPELQAQIEARGLAPLHWADD
DGNPTEQYPLNPNGSPGGVAGVCSLDGRHLALMPHPERAVRLWQWAWQPPPFDALTTSPW
LQLFINARNWTREAGC
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
atgccctcagtccttcacttctatgtccgtccctctggccatgagagggcggcctctgga
cacacgcggaggaagctgcaagggaaattgccagagctgcaggctgtcaagaccgagctg
tgctacaacgtgaactggacagccgactccctcccaagcgccgaggagatgaagaagctc
acgtggctctttggctgccccttgttaccgggtgatgttgcccaggagtcctggctccgt
tctgactccagcgacctgctgctggaggttgggcccaggctgaacttctccaccccagcc
tctaccaacgtcgtgtccgtgtgctgggccgcggggctgggggctgtggatcgcgtggag
actacccggcgctacctgctctcgtttgccaagcccccttcctctgagacgaagaccctg
gctctggctaccctgcatgaccggatgaccgagcagcacttcccgaggcccatccagagc
ttctcccttcggagcatgtcagcacctctcaacggccggatcgacatcctggcagagggc
cggcgtgccctggaaaaagccaaccaggagctaggcctggccctagactcctgggacctg
gatttctacaccaaacgcttccaggagctaaagcggaaccccagcaccgtggaggccttc
gacctggctcagtccaatagcgagcacagccgacactggttcttcaagggccagctccac
atggatgggcaggagatgacgcactccctgtttgaggccatcatgagcactcaggcgtcc
tcgaaccccaacaacgtcctcaagttctgtgacaacagcagcgcaatccaagggaaggag
gtccgattcctacagccagaggaccccacgcgaccaagctgcttccggcagcagcgggcg
ctgagacatgtcgtcttcacggcggagacccacaacttccccacaggagtagcccccttc
agtggggcgaccacaggcaccgggggccggatccgagatgtccagtgcacgggccgtggc
gcccacgtggtggctgggactgctggctactgctttggaaacctgcacatcccaggttac
aatttgccctgggaggacccaagcttccagtatcctgagaactttgcccggcccctggag
gtcgccattgaggccagtaatggggcttctgattacggcaacaagttcggggagccagtg
ctggcaggcttcgcccgctccttgggcctccagctcccggacggccagcggcgtgagtgg
atcaaacccatcatgtttagcgggggcattgggtccatggaagctgagcatgtgagcaag
gagcccccagagccaggcatggacgttgtaaaggttgggggtcccgtctacaggatcgga
gtcgggggtggagccgcctcgtctgtgcaggtgcagggagacaattctagtgacctggac
tttggggctgtgcagcggggagacccggagatggaacagaagatgaaccgtgtgatccgg
gcttgcgtggaggccgccagggggaaccccatctgcagcctccacgaccagggtgccggt
ggcaatggcaacgtcctgaaggagctgagtgacccggctggagctgtcatttacaccagc
cgcttccagctcggggacccgaccctgaacgccctggaaatctggggggccgagtaccag
gagtcgaatgctcttctgctgaggcccgtggaccgagacttcctcagtcgtgtcagcgcc
cgggagcgctgcccagcttgctttgtgggcaccattaccggagacaggaggatcgtgctg
gtggacgatcgggactgtcccgtcgggagaaatggcgaaggggacgccccctcgcccccg
acccctgtggacctggagctggattgggtgctgggcaagatgcctcggaaggagttcttc
ctgcagcggagtctccccgtgctgcggcctctggccttgcccccggggctgagtgtgcgc
caggctctggagcgcgtcctgaggctgcctgctgtggccagcaagcgatacctcaccaac
aaggtggaccgctccgtgggcggcctggtggcgcagcagcagtgcgttgggcccctgcag
acccctctggccgacgtggcggttgtggcattgagtcaccaggagctcgtaggggctgcc
acggctctaggagagcagccggtcaaaagcctgctggaccccaaggttgccgcccgactg
gctgtggccgaagccctcaccaacctggtgtttgctctggtcactgacctccgggacgtg
aagtgcagcgggaactggatgtgggcggccaagctcccgggggagggcgcggctctggcc
gacgcctgcgcggcgatggtggcggtgatggcggccttgggtgtggcggtggacggtggc
aaggactccctcagcatggccgcccgggtcggctctgagaccgtgcgggcccccgggtcg
ctggtcatctcggcctatgctgtctgtccggacatcacagccaccgtgaccccggacctc
aagcgtcctgggggcagaggccggctgctgttcgtgcctctgagccccgggcagcaccgg
ctggggggcacagccctggcccagtgcttctcgcagctgggcgagcagcccccgaacctg
gaccttcccgagaacctggtgcgtgccttccgcatcacacaggggctgctgcgagaccgt
ctcctctgctcaggccacgatgtcagtgacgggggtctcgtcacctgcctgctagagatg
gcctttgctgggaattgtgggatagaggtggacgtgcctgcccctggggtcgatgtgctg
cctacactgttcgccgaggagccgggcctggtgctggaggtgcgggggcccgacctggcc
caggtgctgaagcgctaccgggacgccggcctgtactgcctggagctgggcgccacgggc
gacgctgggccccacgccctggtgcgagtgtccgtgaacggggctgtggttctggaagag
tctgtgaggcagctgcgagccctctgggaggagacgagtttccagctggaccggctgcag
gccgagccgcgctgtgtggcagaggaagagcaggggctcagggagcggacggggcccact
tactgcctgccccccggcttccccaaagcttccgtgccccgagagcctggtggtcccgtt
ccccgggttgccatcttgcgagaggagggcagtaacggagaccgcgagatggcagacggc
ttccactcggccgggttcgaggtgtgggacgtgaccatgcaggacctctgctctggggcg
atcgggctggacacgttccgcggcgtggccttcgtgggtggcttcagctacgcggatgtc
ctgggctctgccaaagggtgggccgctgctgtgaccttccacccgctggccggggctgaa
ctgagacgcttccggaagcggcccgacaccttcagcctgggcgtgtgtaatggctgtcag
ttgctggctctgctgggctgggtgggaggtagccccagcgaggaggcagaggggacgggc
caggactccttgccggcccggccgggcctcctgcttcgccacaacctgtctgggcgcttt
gagtcccgctgggccagcgtgcgggtgggtcctgggccggccctgatgcttcgagggatg
gaaggagctgtgctacccgtgtggagcgctcatggcgaaggttacatggctttttcttct
ccggaactccaagcccagattgaggccaggggcttggctccactgcactgggccgacgac
gacgggaaccccacggaacagtatcccctgaaccccaacgggtccccagggggcgtggct
ggcgtctgctccctcgatggccgccacctggctctcatgcctcaccctgagcgggctgtg
cggctttggcagtgggcgtggcagcctcctccctttgacgctctgactacctccccctgg
ctccagctcttcatcaacgcccgaaactggacccgagaggcgggctgctga
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