Panthera leo (lion): 122207253
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Entry
122207253 CDS
T10741
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
plez Panthera leo (lion)
Pathway
plez00061
Fatty acid biosynthesis
plez00620
Pyruvate metabolism
plez00640
Propanoate metabolism
plez01100
Metabolic pathways
plez01212
Fatty acid metabolism
plez04152
AMPK signaling pathway
plez04910
Insulin signaling pathway
plez04922
Glucagon signaling pathway
plez04936
Alcoholic liver disease
Module
plez_M00082
Fatty acid biosynthesis, initiation
Brite
Enzymes [BR:
plez01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
122207253 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
122207253 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
122207253 (ACACA)
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Ortholog
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Gene cluster
GFIT
Other DBs
NCBI-GeneID:
122207253
NCBI-ProteinID:
XP_042773162
LinkDB
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Position
E1:23624258..23901267
Genome browser
AA seq
2338 aa
AA seq
DB search
MDEPSPLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLS
DLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYQKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRMSFSSNLNH
YGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPE
AGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVEHGIRRLT
FLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRN
FDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGER
LLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRV
LQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPL
HGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLP
SDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYLI
GSFGPQEDLLFLRASELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGY
KYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESS
LAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQ
LGGIQIMHNNGVTHSIVCDDFEGVFTVLHWLSYMPKNVHSLVPLLNSKDPIDRIIEFVPT
KAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAV
ETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRG
FSGGMKDMYDQVLKFGAYIVDSLRECSQPVLVYIPPQAELRGGSWVVIDPTINPRHMEMY
ADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIRLAERLGTPELSAAERKELENKL
KEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLV
KKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVI
EENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST
NT seq
7017 nt
NT seq
+upstream
nt +downstream
nt
atggatgaaccatcccccttggccaaacctctggagctgaaccagcactctcggttcata
attggttctgtatctgaagataactcagaggatgaaatcagcaacctggtgaagctggac
ctactggaggagaaggaaggctctctgtcaccagcttctgttggctcagatacgctctct
gatttggggatttccagcctacaggatggcttggccttgcacatgaggtccagcatgtct
ggcttgcatctagtaaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttc
actgtagcttcaccagcagaatttgttacgcgttttggggggaataaagtgattgagaag
gttcttattgccaacaatggcatcgcagcagtgaaatgcatgcggtccatccgccgatgg
tcttatgagatgtttcgaaatgaacgtgcaatccgatttgttgttatggtcacacctgaa
gacctgaaagccaatgcagaatacattaagatggcagatcactatgtgccggtgccagga
ggaccaaacaacaacaactatgcaaacgtggaattaattcttgatattgctaaaaggatc
ccagtgcaagcagtgtgggctggctggggtcatgcttctgagaatcccaagctcccagaa
cttcttttgaaaaatggcatcgccttcatgggtcctccaagccaggccatgtgggctttg
ggggataagattgcatcttccatagtggctcaaactgctggtatcccaactcttccctgg
agtgggagtggtcttcgtgtggactggcaggaaaatgatttttcaaaacgtatcttaaat
gttccccaggaattatatcaaaaaggttatgtgaaggatgtggatgatgggctgaaggca
gcagaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggagggaaagga
atcagaaaagttaacaatgcagatgacttcccgaacctcttcagacaggttcaagctgaa
gtccctggatctcctatatttgtgatgagactagccaaacaatcccgtcatctggaggta
cagattttagcagatcagtatggcaatgctatctctctgtttggtcgtgactgctctgtg
cagcgcaggcatcagaagattattgaagaagcaccagctgctattgctactccagcagta
ttcgaacatatggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgca
gggactgtcgaatacctctacagccaggatggaagcttctactttctggaactgaaccct
cggctacaggtggagcacccttgtacagagatggtggctgatgtcaacctccctgcagcg
caactccagattgccatggggatccctctgtatagaatcaaggatattcgtatgatgtat
ggagtatctccctggggtgatgctcccattgattttgaaaattctgctcatgttccttgc
ccaaggggccatgttattgctgctcggatcactagtgaaaatccagatgagggttttaag
cccagctcaggaacagttcaggaactgaatttccgtagcaataagaatgtttggggttat
ttcagtgttgctgctgcagggggccttcacgaatttgctgattctcagtttggtcactgc
ttctcctggggagaaaacagagaggaagcaatttcaaacatggtggtggctttgaaggaa
ctatctattcggggtgactttcgaactacagttgaatacctcatcaaattgctggagact
gagagttttcagctgaatagaattgacactggctggctagacagactgatagcagaaaaa
gtacaggcagagcgacctgataccatgttgggagttgtgtgtggggctctccacgtggca
gatgtgagcctacggaatagcatctctaacttccttcattccttagaaaggggtcaagtt
cttcctgctcatacgcttctgaatacagtagatgttgaacttatctatgagggagtcaaa
tatgtacttaaggtgactcgacagtcccccaactcgtatgtggtgatcatgaacggctca
tgcgtagaagtagatgtgcatcggctgagtgatggagggctgctcctgtcctatgatggc
agcagttataccacatacatgaaggaggaagtggatagatatcgtatcacaattggcaat
aagacctgtgtgtttgagaaggaaaatgacccttcagtgatgcgctcaccttctgctggg
aagttaatccagtatattgtggaggatggaggccatgtgtttgctggccagtgctatgct
gagattgaggtgatgaagatggtaatgaccttaacagcagcagagtctggctgtatccat
tatgtcaaacggcctggagcagctcttgaccctggctgtgtgatagccaaaatgcagtta
gacaaccccagcaaggtccaacaggctgagcttcacacgggtagtctgccacggatccag
agcacagcactgagaggcgagaagctccatcgagtgttccattatgtcctggataatctg
gtcaacgtaatgaatggatactgccttccagatcctttttttagtagcagggtaaaagac
tgggtagagcggttgatgaagaccctcagagatccctccttgcctctcctagaattgcaa
gatatcatgaccagtgtctctggccgtattcccccaaatgtggagaagtctatcaagaag
gaaatggctcagtatgccagcaacatcacatcagtcctctgtcagtttcccagccagcag
attgccaacatcctagatagccatgcagctacattgaaccggaaatctgaacgggaagtt
ttcttcatgaacactcagagcattgtccagctggtacagaggtaccgaagtggcatccga
ggccacatgaaggctgttgtgatggatctgctacggcagtacctgcgagtagagacacag
ttccagaatggtcactatgacaaatgtgtgtttgcccttcgagaagagaacaagagtgac
atgaacactgtgctaaactatatcttctctcatgctcaagtcaccaagaagaatcttctg
gtcacaatgcttattgatcagttgtgtggtcgggaccctactctcactgatgagctgctg
aatattctcacagagctaactcaactcagtaagaccaccaatgccaaagtggcacttcga
gcacgccaggttcttattgcctcccatttgccatcatatgagcttcgccataaccaagta
gagtctatcttcctttcagctattgacatgtatggacatcagttttgcattgagaacctg
cagaaactcatcttgtctgaaacatctatttttgatgtcctaccaaacttcttctatcac
agcaaccaggtagtgaggatggcagctctggaggtttatgttcgaagggcttacattgcc
tatgaacttaacagcgtccaacatcgccagcttaaggacaatacctgcgtggtggaattc
cagttcatgctgcccacatcgcatccaaacagaatgtccttctcctccaacctcaaccac
tatggcatgactcacgtagctagtgtcagcgatgtgctgttggacaactcattcactcca
ccgtgtcagcggatgggcggaatggtctcttttcggacttttgaagattttgtcaggatc
tttgatgaagtgatgggctgcttctgtgactccccaccccaaagccccacgttccctgag
gcaggtcacacatctctgtatgatgaagacaaggtccccagggatgaaccaattcacatt
ctgaatgtggctatcaagactgactgtgatattgaggatgacagactggcagctatgttc
agagagtttacccaacaaaataaagctaccctggttgagcatgggatacggcgccttact
ttcctggtcgcacaaaaggatttcagaaaacaggtcaactatgaggtggatcagagattt
catagagaatttcctaaatttttcacgttccgagcaagggataagtttgaggaggatcgt
atctatcgtcacctggagcctgctctagctttccagttagaactgaaccggatgagaaat
tttgaccttactgccattccatgtgctaatcataagatgcacctgtatcttggggcagcc
aaggtggaagtgggcactgaagtgacagactataggttctttgttcgtgcaatcatcaga
cattctgatctggtcaccaaggaagcttcttttgaatatctacaaaatgaaggggagcgg
ctgctcctggaagccatggatgaattggaagttgcttttaataatacaaatgttcgcact
gactgcaaccacatcttcctcaactttgtgcccacagtcattatggacccatcaaagatt
gaggaatctgtgcggagcatggtaatgcgctatggaagtcggctgtggaaattacgtgtc
ctccaggcagaactgaaaatcaacattcgcctgacaccaactggaaaagcaattcccatc
cgcctcttcctgacaaatgagtccggctattacttggacatcagcttgtacaaggaagtg
actgactccaggacagcacagatcatgtttcaggcatatggagacaaacagggaccattg
catggaatgttaatcaacactccatatgtcaccaaagacctacttcaatcaaagagattc
caggcacaatccttggggacaacatacatatatgatatcccagagatgtttcggcagtct
ctgatcaaactctgggagtctatgtccactcaagcattccttccatcaccccccctgcct
tctgacatgctgacatatactgagcttgtgttggatgatcagggtcagctggtccacatg
aacaggcttccaggaggaaatgagattggcatggtagcttggaaaatgacccttaaaagt
cctgaatatccagaaggccgagatatcattgttattggcaatgacatcacatacctaatt
gggtcctttgggccccaggaggatttgctgtttctcagagcttctgagcttgccagggca
gagggtatcccacgcatctttgtagcagccaacagcggagcacgaattggactggcagag
gaaattcgtcatatgtttcacgtggcctgggtagatcctgaggatccttacaagggatac
aaatacttatatctgacccctcaggattataagagggtcagtgctctcaactctgtccac
tgtgaacatgtagaagatgaaggagaatccaggtacaagataactgatattattgggaag
gaagagggacttggagcagagaaccttcgaggctctggaatgattgctggagaatcctca
ttggcctataatgagattatcaccatcagcttggttacatgccgggctattgggattgga
gcttaccttgtccggctgggacagagaaccatccaggttgaaaattctcacttaattctg
accggagctggagctctcaacaaagtccttgggcgggaagtatacacctccaataaccag
cttgggggcatccagatcatgcacaacaatggggtgacccacagcatcgtttgtgatgac
tttgaaggggttttcactgtcctacactggctgtcttacatgcctaagaatgtgcacagt
ttagtacctctcctgaactccaaggatcctatagatagaatcatcgaatttgttcctacg
aaggccccctatgatcctcgatggatgctagcaggccgtcctcacccaacccagaaaggt
cagtggttgagtggattctttgactatggatctttctctgaaatcatgcaaccctgggca
cagactgtggtggttggcagagccaggctaggaggaatacctgtaggagtagttgctgta
gaaacccgaacagtggaactaagtatcccagccgaccctgcaaacctggattctgaagcc
aagataatccagcaggctggccaggtttggtttccagattctgcgtttaagacctatcag
gctatcaaggacttcaaccgcgaagggctgcctctgatggtctttgccaactggagaggc
ttctccggtgggatgaaagatatgtacgaccaggtgctgaagtttggtgcttacatcgtg
gatagcttacgggagtgttcccagcctgtgctggtttacattcctcctcaagctgagctc
cggggtggctcctgggttgtgattgaccccaccatcaacccccggcacatggagatgtat
gctgaccgagaaagcaggggatcagttctggagccagaagggacagtagaaatcaaattc
cgcagaaaagatctggtgaaaaccatgcgtcgggtggacccagtctacattcgcttggct
gaacgattgggcaccccagagctaagcgcagctgagcggaaggagctggagaacaagttg
aaggagcgggaggaattcctaattcccatttaccatcaggtagccgtgcagtttgctgac
ttgcacgacacaccaggacggatgcaggagaagggtgttattaacgacatcctggattgg
aaaacatcccgtaccttcttctactggcggctgaggcgtctcctgctggaggacctggtc
aaaaagaaaatccacaatgccaacccagagctcactgatggtcagatccaggccatgtta
aggcgctggtttgtagaagtggaaggaaccgtgaaggcctatgtttgggacaataacaag
gatctagtggaatggctggagaaacagctgaccgaggaagatggtgttcgctcagtaata
gaggaaaacataaaatacatcagcagagactatgtcctcaagcagatccgcagcttggta
caggccaatcccgaggttgccatggattccatcgtccatatgacccagcacatctcaccc
actcagcgagcagaagtcgtacggatcctctccacgatggactccccttcaacatag
DBGET
integrated database retrieval system
