Panthera leo (lion): 122207376
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Entry
122207376 CDS
T10741
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
plez Panthera leo (lion)
Pathway
plez01521
EGFR tyrosine kinase inhibitor resistance
plez01522
Endocrine resistance
plez04012
ErbB signaling pathway
plez04066
HIF-1 signaling pathway
plez04140
Autophagy - animal
plez04150
mTOR signaling pathway
plez04151
PI3K-Akt signaling pathway
plez04152
AMPK signaling pathway
plez04211
Longevity regulating pathway
plez04213
Longevity regulating pathway - multiple species
plez04350
TGF-beta signaling pathway
plez04371
Apelin signaling pathway
plez04666
Fc gamma R-mediated phagocytosis
plez04714
Thermogenesis
plez04910
Insulin signaling pathway
plez04931
Insulin resistance
plez05163
Human cytomegalovirus infection
plez05165
Human papillomavirus infection
plez05170
Human immunodeficiency virus 1 infection
plez05200
Pathways in cancer
plez05205
Proteoglycans in cancer
plez05207
Chemical carcinogenesis - receptor activation
plez05210
Colorectal cancer
plez05212
Pancreatic cancer
plez05221
Acute myeloid leukemia
plez05224
Breast cancer
plez05225
Hepatocellular carcinoma
plez05226
Gastric cancer
plez05231
Choline metabolism in cancer
plez05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
122207376 (RPS6KB1)
Protein kinases [BR:
plez01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
122207376 (RPS6KB1)
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NCBI-GeneID:
122207376
NCBI-ProteinID:
XP_042773430
UniProt:
A0A8C8WXN5
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Position
E1:complement(26753098..26809109)
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AA seq
525 aa
AA seq
DB search
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
VEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq
1578 nt
NT seq
+upstream
nt +downstream
nt
atgaggcgacgacggaggcgggacggcttttacccagcgccggacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggaacattgtgagaaatttgaaatatcggaaactagcgtgaac
agagggccagaaaaaatcagaccagaatgtttcgagctacttcgggtacttggtaaaggg
ggctatggaaaggtttttcaagtacggaaagttacaggagcaaatactgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagaacggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagaccggtggaaaactctacctcatccttgagtatctcagcggaggagaatta
tttatgcagttagaaagagaaggaatatttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgctaaatcaccaaggtcatgtgaaactaacagactttggactatgc
aaggaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtttggga
gcattaatgtatgacatgctgactggagcacccccgttcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtcttggagctggtcct
ggggatgctggagaagttcaagctcatccattcttcaggcatattaattgggaagaactg
ctggctaggaaggtggaacccccttttaaacctctgttgcaatctgaggaggatgtgagt
cagtttgattcaaagtttacacgtcagacacctgttgacagcccagatgactcaactctc
agtgaaagtgccaaccaggtctttctgggttttacatatgttgctccatctgtacttgaa
agtgtgaaagaaaaattttcctttgaaccaaaaatccgatcacctcgaagatttattggc
agcccgcgaacacctgtcagcccagtcaaattttctcctggggatttctggggaagaggt
gcttcagccagcacggcaaatcctcagacacctgtggaatatccaatggaaacaagtgga
gtagagcagatggatgtgacgatgagtggggaagcttcagcaccacttcccatacgacag
ccgaactctgggccatacaaaaaacaagctttccccatgatctccaaacgaccagagcac
ctacgtatgaatctatga
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