KEGG   Panthera leo (lion): 122207795
Entry
122207795         CDS       T10741                                 
Symbol
BAX
Name
(RefSeq) apoptosis regulator BAX isoform X1
  KO
K02159  apoptosis regulator BAX
Organism
plez  Panthera leo (lion)
Pathway
plez01521  EGFR tyrosine kinase inhibitor resistance
plez01522  Endocrine resistance
plez01524  Platinum drug resistance
plez04071  Sphingolipid signaling pathway
plez04115  p53 signaling pathway
plez04141  Protein processing in endoplasmic reticulum
plez04210  Apoptosis
plez04211  Longevity regulating pathway
plez04215  Apoptosis - multiple species
plez04217  Necroptosis
plez04722  Neurotrophin signaling pathway
plez04932  Non-alcoholic fatty liver disease
plez04933  AGE-RAGE signaling pathway in diabetic complications
plez05012  Parkinson disease
plez05014  Amyotrophic lateral sclerosis
plez05016  Huntington disease
plez05020  Prion disease
plez05022  Pathways of neurodegeneration - multiple diseases
plez05132  Salmonella infection
plez05152  Tuberculosis
plez05160  Hepatitis C
plez05161  Hepatitis B
plez05162  Measles
plez05163  Human cytomegalovirus infection
plez05164  Influenza A
plez05165  Human papillomavirus infection
plez05166  Human T-cell leukemia virus 1 infection
plez05167  Kaposi sarcoma-associated herpesvirus infection
plez05168  Herpes simplex virus 1 infection
plez05169  Epstein-Barr virus infection
plez05170  Human immunodeficiency virus 1 infection
plez05200  Pathways in cancer
plez05202  Transcriptional misregulation in cancer
plez05203  Viral carcinogenesis
plez05210  Colorectal cancer
plez05212  Pancreatic cancer
plez05213  Endometrial cancer
plez05214  Glioma
plez05216  Thyroid cancer
plez05217  Basal cell carcinoma
plez05218  Melanoma
plez05220  Chronic myeloid leukemia
plez05222  Small cell lung cancer
plez05223  Non-small cell lung cancer
plez05224  Breast cancer
plez05225  Hepatocellular carcinoma
plez05226  Gastric cancer
plez05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:plez00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    122207795 (BAX)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    122207795 (BAX)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    122207795 (BAX)
   04215 Apoptosis - multiple species
    122207795 (BAX)
   04217 Necroptosis
    122207795 (BAX)
   04115 p53 signaling pathway
    122207795 (BAX)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    122207795 (BAX)
  09149 Aging
   04211 Longevity regulating pathway
    122207795 (BAX)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122207795 (BAX)
   05202 Transcriptional misregulation in cancer
    122207795 (BAX)
   05203 Viral carcinogenesis
    122207795 (BAX)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122207795 (BAX)
   05212 Pancreatic cancer
    122207795 (BAX)
   05225 Hepatocellular carcinoma
    122207795 (BAX)
   05226 Gastric cancer
    122207795 (BAX)
   05214 Glioma
    122207795 (BAX)
   05216 Thyroid cancer
    122207795 (BAX)
   05220 Chronic myeloid leukemia
    122207795 (BAX)
   05217 Basal cell carcinoma
    122207795 (BAX)
   05218 Melanoma
    122207795 (BAX)
   05213 Endometrial cancer
    122207795 (BAX)
   05224 Breast cancer
    122207795 (BAX)
   05222 Small cell lung cancer
    122207795 (BAX)
   05223 Non-small cell lung cancer
    122207795 (BAX)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122207795 (BAX)
   05170 Human immunodeficiency virus 1 infection
    122207795 (BAX)
   05161 Hepatitis B
    122207795 (BAX)
   05160 Hepatitis C
    122207795 (BAX)
   05164 Influenza A
    122207795 (BAX)
   05162 Measles
    122207795 (BAX)
   05168 Herpes simplex virus 1 infection
    122207795 (BAX)
   05163 Human cytomegalovirus infection
    122207795 (BAX)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122207795 (BAX)
   05169 Epstein-Barr virus infection
    122207795 (BAX)
   05165 Human papillomavirus infection
    122207795 (BAX)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    122207795 (BAX)
   05152 Tuberculosis
    122207795 (BAX)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    122207795 (BAX)
   05014 Amyotrophic lateral sclerosis
    122207795 (BAX)
   05016 Huntington disease
    122207795 (BAX)
   05020 Prion disease
    122207795 (BAX)
   05022 Pathways of neurodegeneration - multiple diseases
    122207795 (BAX)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122207795 (BAX)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    122207795 (BAX)
   04933 AGE-RAGE signaling pathway in diabetic complications
    122207795 (BAX)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    122207795 (BAX)
   01524 Platinum drug resistance
    122207795 (BAX)
   01522 Endocrine resistance
    122207795 (BAX)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:plez03029]
    122207795 (BAX)
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:plez02000]
    122207795 (BAX)
Mitochondrial biogenesis [BR:plez03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Fission and Fusion factors
    122207795 (BAX)
Transporters [BR:plez02000]
 Other transporters
  Pores ion channels [TC:1]
   122207795 (BAX)
SSDB
Motif
Pfam: Bcl-2 TetR_C_30 CF222
Other DBs
NCBI-GeneID: 122207795
NCBI-ProteinID: XP_042773917
LinkDB
Position
E2:complement(8878812..8882635)
AA seq 205 aa
MSHPSSLNPLGPKSPGTSSLLSPLGPTSSEQIMKTGALLLQGFIQDRAGRMGGETPELAL
EQVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAAEMFSDGNFNW
GRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGT
PTWQTVTIFVAGVLTASLTIWKKMG
NT seq 618 nt   +upstreamnt  +downstreamnt
atgagccaccctagttccctgaatcccctaggacccaagagtccaggcacgtcttccctc
ctttctcctctagggcccaccagctctgagcagatcatgaagacaggggcccttttgctt
cagggtttcatccaagatcgggcagggcgaatggggggagagacacccgagctggccctg
gagcaggtgccccaggatgcgtccaccaagaagctgagcgagtgtctcaagcgcatcgga
gatgaactggacagtaacatggaattgcagaggatgatcgcagctgtggacacagactcc
ccccgcgaggtctttttccgagtggcagcggagatgttttccgatggcaacttcaactgg
ggccgggtcgttgccctcttctactttgccagcaaactggtgctcaaggccctgtgtacc
aaggtgcccgagctgatccggaccatcatgggctggacactggacttccttcgagagcgg
ctgctgggctggatccaggaccagggtggttgggacggcctcctctcctactttgggaca
cccacgtggcagacagtgaccatctttgtggccggagtgctgactgcgtcactcaccatc
tggaaaaagatgggctga

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