Panthera leo (lion): 122208268
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Entry
122208268 CDS
T10741
Symbol
KMT2B
Name
(RefSeq) histone-lysine N-methyltransferase 2B
KO
K14959
[histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:
2.1.1.354
]
Organism
plez Panthera leo (lion)
Pathway
plez00310
Lysine degradation
plez01100
Metabolic pathways
Brite
Enzymes [BR:
plez01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
122208268 (KMT2B)
Transcription factors [BR:
plez03000
]
Eukaryotic type
Zinc finger
CXXC CpG-binding proteins
122208268 (KMT2B)
Chromosome and associated proteins [BR:
plez03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
122208268 (KMT2B)
HMT complexes
MLL3/MLL4 complex
122208268 (KMT2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SET
FYRC
FYRN
PHD
zf-CXXC
zf-HC5HC2H
zf-HC5HC2H_2
Bromodomain
Motif
Other DBs
NCBI-GeneID:
122208268
NCBI-ProteinID:
XP_042775115
LinkDB
All DBs
Position
E2:complement(17849177..17869511)
Genome browser
AA seq
2717 aa
AA seq
DB search
MAAAAGGGSCPGPGSARGRFPGRPRGSGGGGGRGGRGSGAERVRVALRRGGGATGPGGAE
PGEDTALLRLLGLRRGLRRLRRLWAGPRIQRGRGRGRGRGWGPSRGCVPEESSDEESDDE
EFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPIAPPRLADVAPTPPKTPARKR
GEEGTERMVQALTELLRRAQAPPAPRGRTCEPSTPRRSRGRPPGRPAGPCRKKQQAVVVA
EAAVTIPKPEPPPPVVPVKHRTGSWKCKEGPGPGPGTPKRGGQAGRGGRGGRGRGRGGLP
LVIKFVSKAKKVKMGQLSLGVESGQGQDQREESWQDAPQGRAGSGQGEGPCWRKEQKLEE
EREKETEEEKGKEKEEEKVEGAGPEEMMLAEEKEEAELPPPPPPPPPPPPLPPLPPPSTS
PSSPLCPPPPPVSPLPPPSPPPPPAPEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREA
ARAVPEGTPPTPTPSTTTGGPLEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRR
FMDEDPPKPLKVEVSPTLRPPVAMSPLAPPEPAPAPSPPRAPTPPSTPVPLPEKRRSILR
EPTFRWTSLTRELPPPPPAPPPAPPPLPAPVTPSRRPLLLRAPQFTPSEAHLKIYESVLT
TPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVATPVKAEVPLPGAPTLS
NGQQPQPQAQLQQPLQALQTQLLPQPLPPQQPQLQPQLQLQPQPPPQQPPPLEKARVAGL
GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVASLLPPSPGGQMEEVVGTVKQLSERG
SVRSEDESMETKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD
RQDIATEDTSSASETESVPSRSRRGKVESAGPGGDSEPAGSGGTLAQTPRRSLPSHHGKK
MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG
RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAPPGPEEQDSLLLQRKSARRC
VKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPVPEPEEQSRPRKPTLQPVLQLKARR
RLDKDALAPGPFTSFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGG
PPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKG
RGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWS
GDYSLCPRCTQLYEKGNFCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEIL
SGLPDSVLYTCGPCAGATHPRWREALSGALQGGLRQVLQGLLSSKVAGPLLLCTQCGQAG
KQLHPGPCDLQAVSRRFEEGHYKSVHSFMEDMVGILMKHSEEGETPERRAGGQMKGLLLK
LLESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGD
PSAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVF
EENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKK
VFCQKHTDLLDGKEIVTPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDS
LGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPVHLEAAE
ENQTIVHSPTPSSEPPDHVDPPPDTDALIPGAPEHHSPVQNLDPPLRPDLSIAPPPAPRS
FSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDLDFPAPPRRSRRPSPL
TPRLPPSRRASPPLRTSPQLRVPPPTSVVRALTPTSGELAPPGPAPSPPPPPEDLGPDFE
DMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAVGSSHGGPGDSSEEEASPTPRYVHFP
VTVVSGPALAPGALPGTPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVGRAGVIGA
AGDRTRPPEDLPSEIVDFVLKNLGGPGEGGAGPREEPLPPAPPLANGSQPSQGLPPSPAD
PTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVSPPVKQP
PLPPPIPPTAPASWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPPSPPHQAIRV
KRVSTFSGRSPPAPPPNKTPRLEEDGESLEDAPQGPGLSGSGFSRVRMKTPTVRGVLDLD
EPGEPTGEESPRPLQDRSPLLSLPEGGPPRAPDGPPDLLLESQWHHYSGEASSSEEEPPS
PEDKENQAPKRAGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSG
MSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRK
CTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVG
VYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDV
VDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDAS
NKLPCNCGAKRCRRFLN
NT seq
8154 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcgggcggcggcagttgccccgggcctggctccgcgcggggccgcttc
ccgggccggccgcggggctccggcgggggcgggggccgcggcggacggggcagcggagcc
gagagagtgcgggtagctctgcggcgcggcggcggcgcgacggggccgggcggagccgag
cctggggaggacacggccctgctccgtttgctggggctccgccggggcctgcgccggctc
cgccgcctgtgggccggcccgcgcattcagcggggccgaggcaggggccggggcaggggc
tggggccccagccggggctgcgtgcctgaggagagcagtgacgaggaatccgacgatgag
gagtttcagggttttcattcagatgaagatgtggcccccagttccctgcgctctgcgctc
cgatcccagcgaggtcgagccccccgaggtcggggccgcaagcataagacgacccccatt
gcgcctcctcgcctagcagatgttgctcctacccccccaaagactcctgcccggaaacgg
ggtgaggaaggcacagaacggatggtacaggcactgactgaacttctccggcgggcccag
gcacccccagccccccggggccggacatgtgagccttccactccacgtcggtctcgggga
cggcccccaggacggccagcaggcccctgcaggaagaagcaacaagcagtagtggtggca
gaagcagctgtgacaatccccaaacccgagcccccacctcctgtggttccagtaaaacac
cgaactggcagctggaagtgcaaggaggggcccggcccaggacctgggacccctaagcgt
ggaggacaggctgggcgaggaggccgtggaggtagaggccgaggccgaggcgggctccct
ctcgtcatcaagtttgtttcaaaggccaaaaaagtgaagatgggacagttgtccttggga
gttgaatcaggtcagggtcaagatcaacgtgaggagagctggcaggatgccccccaagga
agagctggatctggacagggagagggcccctgctggaggaaagagcaaaagctggaggag
gagagagagaaggagacagaagaggagaaaggcaaggagaaggaggaagagaaggtagag
ggagctggacctgaagagatgatgctagcggaggaaaaggaagaggcagagctccctcca
ccccctccacccccaccacccccaccaccccttccccccctccctcctccctcaacttct
ccttcgtccccactttgtcctccaccacccccagtgtcccctctgcccccaccatcacct
ccaccacctcctgccccagaggagcaggaagaatcccctcctccagtggttccagctaca
tgctccaggaagaggggccggcctcccctgactcccagccagcgggcagagcgagaagct
gctcgggcagtgccagaaggtactcctcccactccaacccccagcaccaccacgggaggc
cctctggaagacagccccactgtggcccccaaaagtaccaccttcctgaagaatatccgg
cagtttattatgcccgtggtgagtgcccgctcctcccgtgtcatcaagacaccccggcga
tttatggacgaagacccccccaagcccctaaaggtagaagtctcacctactctgcggcct
cctgtcgccatgtccccactcgcccccccagaaccggcaccagctccctctccaccgcgt
gccccaactcccccctctaccccagtcccgcttcctgaaaagagacggtccattctaagg
gaacccacatttcgctggacctcactgacccgggaactgccccctcctcctcctgctcct
ccaccggccccacccccacttcctgcccctgtcactccatcccggaggcccctgctcctt
cgggcgcctcagtttaccccaagcgaagcccacctgaagatctacgaatcggtgcttact
actcctcttggggcccctgaagcccctgagccagagcctcctcccgccgatgactctcca
gctgagcctgagccacgggcagtgggccgcaccaaccacctcagcctgcctcgatttgcc
cctgtggtcgccactcctgtcaaggccgaggtgccccttcctggggcgccaactctgagc
aatgggcagcagcctcagcctcaggctcagctacagcagcccctacaggccttgcaaacc
cagctgctgccccagccattaccaccacagcagccacaattacagccacagttacaactg
cagccacagcctccaccacagcagccgccgccactggaaaaggcccgtgttgcaggcttg
ggttccttaccactgtctggtgtggaggagaaaatgttcagcctcctcaagagagccaag
gtgcagctgttcaagatcgatcagcagcagcagcagaaggtggcgtctttgttgccgccg
agccctggagggcagatggaggaagtcgtggggactgtcaagcaactctcagagagaggt
tctgtcaggtctgaagatgaatcgatggaaactaagagagagagaccgtcgggccccgag
tcccccgtgcaaggcccccgcatcaaacatgtctgtcgtcatgctgctgtggccctaggt
caggcccgggccatggtgcccgaagacgtcccccgcctcagtgctcttcctctccgggat
cggcaggacatcgccacggaggatacatcatcagcatctgagactgagagtgtcccatca
cggtctcggcggggaaaggtggagtcagcagggcctgggggagactcagagcctgccggg
tctggagggaccctggcccaaacgccccggcgctcgctgccctcccatcatggcaagaag
atgcggatggcacggtgtggacactgtcggggctgcctgcgtgtgcaggactgtgggtcc
tgtgtcaactgcctggacaagcccaagtttgggggccccaacaccaagaagcagtgctgt
gtataccggaagtgtgacaagatagaggctcggaagatggaacggttggctaaaaaaggc
cggacgatagtgaagacgctgttgccctgggattccgatgaatctcctgaggcctcccct
ggtcctccaggcccacgccggggggcgggagctggggggccccgggaggaggtggtggcc
cccccagggcccgaggagcaggactccctcctactgcagcgcaagtcagcccggcgctgc
gtcaaacagcgaccctcctatgatatcttcgaggactcggatgactcagagcctgggggt
ccccctgctccccggcgtcggaccccccgagagaatgagctaccagtaccagaacctgag
gagcagagccggccccgcaaacccaccctgcagcctgtgttgcagcttaaggcccgaagg
cgcctggacaaggacgctctggcccctggcccctttacttcttttcccaatggttggact
ggaaaacagaagtcccctgacggagtgcaccgggtccgtgtggattttaaggaggattgt
gacctggagaacgtgtggctgatgggcggcctcagtgtgctcacctccgtgccagggggg
ccgccaatggtgtgcttgctgtgtgccagtaaaggcctgcatgagctggtgttctgccaa
gtctgctgtgaccctttccatccattctgtctggaggaggccgaacggcccctgccccaa
catcatgacacctggtgctgccgccgctgcaagttttgccacgtctgtgggcgcaaaggc
cggggatccaagcacctcctggagtgtgagcgctgccgccatgcttatcatccagcctgc
ctggggcccagctacccaacccgggccacacgcaaacggcgccactggatctgctcagcc
tgcgtacgctgtaagagctgtggggcgactccagggaagaactgggacgtcgagtggtct
ggagattacagcctctgccccaggtgcacccagctctatgagaaaggaaatttctgccca
atctgcacacgctgctacgaagacaacgactacgagagcaagatgatgcagtgtgcacag
tgtgaccactgggtgcacgccaagtgcgagggactctcggatgaagattatgagatcctt
tctgggctgccagactccgtgctatatacctgcggaccgtgtgcgggggccacgcacccc
cgctggcgagaggccctgagtggggccctgcaggggggcctacgccaggtgctccagggc
ctactgagctccaaggtggcgggcccattgctgctgtgcactcagtgtgggcaggctgga
aagcagctgcacccggggccctgtgatctgcaagccgtgagtcggcggttcgaggaaggc
cactacaagtccgtgcacagctttatggaggacatggtgggcatcctgatgaagcactca
gaagaaggagaaaccccagagcgccgggctggaggccagatgaaggggctcctactgaag
ctgctagagtctgcgttcggctggttcgacgcccatgaccccaagtactggcgacggagt
acccggctgccgaacggagttcttcccaatgccgtgttacctccatccttggaccatgtc
tacgctcagtggaggcagcaggaaccagagaccccagaatcagggcagcctccaggggac
ccctcggcagcttttcagggcaaggatccagctgctttctcacacctggaggacccccgt
cagtgtgcgctctgcctcaaatatggggatgcagactctaaggaggcgggacggcttcta
tacattgggcagaatgagtggacacatgtcaactgtgccatttggtcagctgaagtgttt
gaggaaaatgatggctccctcaaaaacgtgcatgctgccgtagctcgagggaggcagatg
cgctgtgagctctgcctgaagcctggagccacggtgggctgctgcctttcctcctgcctc
agcaacttccacttcatgtgcgcccgggccagctactgcatcttccaggacgacaagaaa
gttttctgtcagaaacacacagacctgctggatggcaaggagattgtgacccccgatggg
tttgatgttctccgccgagtctatgtggactttgagggcatcaacttcaagcgaaagttc
ttgacggggctcgaacctgatgccatcaatgtgctcattggttccatccgaattgactcc
ttgggtaccctgtctgatctctcggactgcgagggacggctcttccccattggctaccag
tgctcccgtctgtactggagcacagtggatgctcggcggcgctgctggtatcggtgtcgt
attctggagtatcgtccgtggggtccaagggaagagccagttcacctggaggcagcagag
gagaaccagaccattgtgcacagccccaccccttcctcagaacccccggatcatgtggac
cccccgccagatacagatgcccttatccctggagctcctgagcaccactcacctgttcag
aacctggaccccccacttcggccagatctcagcattgcccctcctccagccccccgttcc
ttctcaggggctcgaatcaaagtgcccaactactcaccatcccggaggcccttggggggt
gtctcctttggacccctgccctcccctggaagtccatcttctctgacccaccacatccct
acggtgggagacctggactttccagctccccccagacgctcccgtcgtcccagccccctg
accccaaggctgccaccgtcgcggcgggcctctccccctctcagaacctccccacagctc
agggtgccccctcctacctcagtcgttagagccctcacacctacctcaggggagctggct
ccccctggcccagccccatctcctccaccaccccctgaagacctgggcccagactttgag
gacatggaggtggtgtcaggactgagtgctgctgacctggactttgcggccagcctgctg
gggactgagcccttccaggaagagattgtggccgcaggggcagtggggagcagccacggg
ggtccaggggacagctcagaggaggaggctagccctaccccccgctatgtccacttccct
gtgactgtggtgtctggccctgccctggcccctggtgccctccctggaaccccccgcatc
gaacagctggacggagtggatgacggcacagacagcgaagcagaggcagtccagcagcct
cggggccaggggactcctccttcggggccaggagtgggccgggctggggtcatcggggct
gcaggggacagaacccgacctcctgaggacttgccgtcagaaattgtggattttgtgttg
aagaacctaggagggcctggagagggaggtgctggacccagagaggaacccctcccccca
gcacctcccctggccaatggcagccagccttcccagggcctaccccctagcccagctgac
cccactcggacgtttgcctggctccctggggccccaggggtccgggtattgagcctgggc
cctgcccctgagccccccaaacccgccacatccaaaatcatccttgtcaacaagttgggg
caagtctttgtgaagatggctggggagggtgaacccgtctcacccccagtgaagcagcca
cctctgccccctcccatcccccctacagcccctgcttcctggactctgcccccaggaccg
ctgctgggtgtgttgccagtggtaggggtggtccgccccgccccacccccaccccctcct
ccactgaccctggtgttgagcagtggaccccccagcccaccccatcaggccatccgcgtc
aagagggtgtccaccttctctggccgttccccaccagcgcctcccccaaacaagactccc
cggctggaggaagatggagagtccttggaggatgccccccagggtccagggcttagtggc
agcgggtttagccgagtaaggatgaaaacgcccacagtgcgtggagttcttgacttggat
gagcctggggagcccacgggggaggaaagcccaaggcccctccaggaccggtcccctctg
ctgtcactcccagaaggtggtcctcctcgggcccctgatggtccccccgacctgctgctt
gagtcccagtggcaccactactcaggtgaggcttcgagctccgaggaagagcctccatcc
ccagaggacaaagagaaccaggcccccaaacgggctggcccacatctacgctttgagatc
agcagtgaggatgggttcagcgtggaggcagagagcttggagggggcgtggagaactctg
attgagaaggtgcaagaggcccgagggcacgcccgcctccgacatctctccttcagtgga
atgagcggggcaaggctcctgggcatccaccacgacgctgtcatcttcctggcagagcag
cttcccggggcccagcgctgccagcactataagttccgctaccaccagcagggagagggc
caggaggaaccacccctgaatccccacggggcagcccgtgccgaggtctatctccggaag
tgtacctttgacatgttcaacttcctggcctcccagcaccgtgtgctccctgagggagcc
acctgtgacgaggaagaggatgaggtgcagctcaggtcaaccagacgtgccaccagcctg
gagctgcccatggccatgcgctttcgccacctcaagaagacatccaaagaggctgtgggt
gtctacagatctgccatccatgggcggggcctgttctgtaagcgcaacatcgatgccggc
gagatggtcattgagtattccggtatcgtcattcgctctgtgctgactgacaagcgggag
aagttctacgacgggaagggtatcgggtgctacatgttccgcatggatgactttgatgtg
gtggatgccacaatgcacggcaacgctgcccgcttcatcaaccactcgtgtgagcccaac
tgcttctctcgggtcatccacgtggagggccagaagcacatcgtcatcttcgccctgcgc
cgcatcctgcgtggtgaggagctcacctacgactacaagttccccattgaggatgccagc
aacaagctgccctgcaactgtggcgccaagcgctgccgtcggttcctgaactga
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integrated database retrieval system
