KEGG   Panthera leo (lion): 122209186
Entry
122209186         CDS       T10741                                 
Symbol
CREB5
Name
(RefSeq) cyclic AMP-responsive element-binding protein 5 isoform X1
  KO
K09047  cyclic AMP-responsive element-binding protein 5
Organism
plez  Panthera leo (lion)
Pathway
plez04022  cGMP-PKG signaling pathway
plez04024  cAMP signaling pathway
plez04151  PI3K-Akt signaling pathway
plez04152  AMPK signaling pathway
plez04211  Longevity regulating pathway
plez04261  Adrenergic signaling in cardiomyocytes
plez04668  TNF signaling pathway
plez04714  Thermogenesis
plez04725  Cholinergic synapse
plez04728  Dopaminergic synapse
plez04911  Insulin secretion
plez04915  Estrogen signaling pathway
plez04918  Thyroid hormone synthesis
plez04922  Glucagon signaling pathway
plez04925  Aldosterone synthesis and secretion
plez04926  Relaxin signaling pathway
plez04927  Cortisol synthesis and secretion
plez04928  Parathyroid hormone synthesis, secretion and action
plez04931  Insulin resistance
plez04934  Cushing syndrome
plez04935  Growth hormone synthesis, secretion and action
plez04962  Vasopressin-regulated water reabsorption
plez05016  Huntington disease
plez05020  Prion disease
plez05030  Cocaine addiction
plez05031  Amphetamine addiction
plez05034  Alcoholism
plez05161  Hepatitis B
plez05163  Human cytomegalovirus infection
plez05165  Human papillomavirus infection
plez05166  Human T-cell leukemia virus 1 infection
plez05203  Viral carcinogenesis
plez05207  Chemical carcinogenesis - receptor activation
plez05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:plez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    122209186 (CREB5)
   04024 cAMP signaling pathway
    122209186 (CREB5)
   04022 cGMP-PKG signaling pathway
    122209186 (CREB5)
   04151 PI3K-Akt signaling pathway
    122209186 (CREB5)
   04152 AMPK signaling pathway
    122209186 (CREB5)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    122209186 (CREB5)
   04922 Glucagon signaling pathway
    122209186 (CREB5)
   04915 Estrogen signaling pathway
    122209186 (CREB5)
   04926 Relaxin signaling pathway
    122209186 (CREB5)
   04935 Growth hormone synthesis, secretion and action
    122209186 (CREB5)
   04918 Thyroid hormone synthesis
    122209186 (CREB5)
   04928 Parathyroid hormone synthesis, secretion and action
    122209186 (CREB5)
   04925 Aldosterone synthesis and secretion
    122209186 (CREB5)
   04927 Cortisol synthesis and secretion
    122209186 (CREB5)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122209186 (CREB5)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    122209186 (CREB5)
  09156 Nervous system
   04725 Cholinergic synapse
    122209186 (CREB5)
   04728 Dopaminergic synapse
    122209186 (CREB5)
  09149 Aging
   04211 Longevity regulating pathway
    122209186 (CREB5)
  09159 Environmental adaptation
   04714 Thermogenesis
    122209186 (CREB5)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    122209186 (CREB5)
   05203 Viral carcinogenesis
    122209186 (CREB5)
  09162 Cancer: specific types
   05215 Prostate cancer
    122209186 (CREB5)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122209186 (CREB5)
   05161 Hepatitis B
    122209186 (CREB5)
   05163 Human cytomegalovirus infection
    122209186 (CREB5)
   05165 Human papillomavirus infection
    122209186 (CREB5)
  09164 Neurodegenerative disease
   05016 Huntington disease
    122209186 (CREB5)
   05020 Prion disease
    122209186 (CREB5)
  09165 Substance dependence
   05030 Cocaine addiction
    122209186 (CREB5)
   05031 Amphetamine addiction
    122209186 (CREB5)
   05034 Alcoholism
    122209186 (CREB5)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    122209186 (CREB5)
   04934 Cushing syndrome
    122209186 (CREB5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:plez03000]
    122209186 (CREB5)
Transcription factors [BR:plez03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    122209186 (CREB5)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 bZIP_Maf TolA_bind_tri ZapB Rab11-FIP3 NDUFB11
Other DBs
NCBI-GeneID: 122209186
NCBI-ProteinID: XP_042776880
LinkDB
Position
A2:118756566..119238931
AA seq 510 aa
MVHTEIYEESKMNLEQERPFVCSAPGCSQRFPTEDHLMIHRHKHEMTLKFPSIKTDSMLS
DQTPTPTRFLKNCEEVGLFNELDCSLEHEFRKAQEEESSKRNISMHNTVGGAMAGPGAHQ
LGSTRMPNHDTSVVIQQAMPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLHNRQRQPMP
ASMPGTLPNPTMPGSSAVSMPMERQMSVNSNLLGMQGPNLSNPCASPQVQPMHSEAKMRL
KAALTHHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPAHHPYPHQHQH
PAHHPHPQPHHQQNHPHHHSHLHAHPAHHQTSPHPPLHSGNQAQVSPATQQMQPTQTIQP
PQPTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQ
NEVSMLKNEVAQLKQLLLTHKDCPITAMQKESQGYLSPESSPPASPVPACSQHQVIQHNT
VTTSSAVSEVVGSSTLSQLTTHRTDLNPIL
NT seq 1533 nt   +upstreamnt  +downstreamnt
atggtgcatacagagatttatgaggaatccaagatgaatttggagcaggagaggccgttt
gtctgcagtgccccaggctgttcgcagcgcttcccaacagaggaccatctgatgattcat
aggcacaagcatgaaatgactttgaagttcccctcaataaaaacagacagtatgttatca
gatcagactccgaccccaacgagattcctgaagaactgtgaggaggtggggctcttcaat
gagctggactgctcccttgagcatgagttcaggaaggctcaggaggaggagagcagcaag
cggaatatctcgatgcataacacagttggtggggccatggcggggcccggagctcaccag
cttggcagcacccggatgcccaaccatgacaccagcgttgtgattcagcaagccatgccg
tcgccccagtccagctctgtcatcacacaggcaccttccaccaaccgccagatcgggcct
gtcccaggctctctatcttctctgctacatctccacaacagacagagacagcccatgcca
gcctccatgcctgggaccctgcccaacccaacaatgccgggatcttctgccgtctcgatg
ccaatggagagacaaatgtcagtgaactccaacctcctgggaatgcaaggtccaaatctc
agcaacccctgtgcttctccccaagtccagccaatgcattcagaagccaaaatgaggttg
aaggccgcgttgactcaccaccccgctgccatgtcaaatgggaatatgaacaccatggga
cacatgatggaaatgatgggctcccggcaggaccagacgccacaccatcacatgcactcg
cacccacatcagcaccagacgctgccagcccatcacccctacccgcaccagcaccagcac
ccagcccaccatcctcaccctcaaccccatcaccagcagaaccacccacatcatcactcc
caccttcacgcacaccctgcacatcaccagacctcgccacacccacccctgcactccggc
aaccaagcacaggtttcaccagcgacacaacagatgcagccgacccagacaatacagccg
ccccagcccacaggggggcgccggcgaagggtggtggatgaggatcccgacgagaggcgg
aggaaatttctggaacggaaccgggccgctgccacccgctgcagacagaagaggaaggtc
tgggtgatgtcactggaaaagaaagcagaagaactcacccagacaaacatgcagcttcag
aatgaagtgtccatgttgaaaaatgaggtggcccagctgaaacagttgttgttaacacat
aaagactgtccaataacagccatgcagaaagaatcacaaggatatctaagtccggagagc
agtcctcccgccagccccgtcccagcttgctctcagcaccaggtcatccaacataatacc
gtcaccacttcctctgcagtgagcgaggtggtgggaagctccaccctcagtcagctcacc
actcacagaacagacctgaatcccatcctttaa

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