Panthera leo (lion): 122210195
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Entry
122210195 CDS
T10741
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
plez Panthera leo (lion)
Pathway
plez01521
EGFR tyrosine kinase inhibitor resistance
plez04010
MAPK signaling pathway
plez04014
Ras signaling pathway
plez04015
Rap1 signaling pathway
plez04020
Calcium signaling pathway
plez04151
PI3K-Akt signaling pathway
plez04360
Axon guidance
plez04510
Focal adhesion
plez04520
Adherens junction
plez05100
Bacterial invasion of epithelial cells
plez05144
Malaria
plez05200
Pathways in cancer
plez05202
Transcriptional misregulation in cancer
plez05205
Proteoglycans in cancer
plez05206
MicroRNAs in cancer
plez05208
Chemical carcinogenesis - reactive oxygen species
plez05211
Renal cell carcinoma
plez05218
Melanoma
plez05223
Non-small cell lung cancer
plez05225
Hepatocellular carcinoma
plez05226
Gastric cancer
plez05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122210195 (MET)
04014 Ras signaling pathway
122210195 (MET)
04015 Rap1 signaling pathway
122210195 (MET)
04020 Calcium signaling pathway
122210195 (MET)
04151 PI3K-Akt signaling pathway
122210195 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
122210195 (MET)
04520 Adherens junction
122210195 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
122210195 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122210195 (MET)
05202 Transcriptional misregulation in cancer
122210195 (MET)
05206 MicroRNAs in cancer
122210195 (MET)
05205 Proteoglycans in cancer
122210195 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
122210195 (MET)
05230 Central carbon metabolism in cancer
122210195 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
122210195 (MET)
05226 Gastric cancer
122210195 (MET)
05218 Melanoma
122210195 (MET)
05211 Renal cell carcinoma
122210195 (MET)
05223 Non-small cell lung cancer
122210195 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
122210195 (MET)
09174 Infectious disease: parasitic
05144 Malaria
122210195 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122210195 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122210195 (MET)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122210195 (MET)
Protein kinases [BR:
plez01001
]
Receptor tyrosine kinases (RTK)
MET family
122210195 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
PSI
Kinase-like
Pkinase_fungal
Linker_histone
Ninjurin
Motif
Other DBs
NCBI-GeneID:
122210195
NCBI-ProteinID:
XP_042778671
LinkDB
All DBs
Position
A2:133638854..133750958
Genome browser
AA seq
1382 aa
AA seq
DB search
MKAPAVLAPGILVLLFTLVQKSYGECREALVKSEMNVNMKYQLPNFTAETPIQNVVLHKH
HIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGVWKDNINMAL
LIDTYYDDQLISCGSVHRGTCQRHVLPPSNTADILSKVHCMYSPQADEESSHCPDCVVSA
LGTKVLISEKGRFINFFVGNTINSSYLTDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPIKYIHAFESNRFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECI
LTEKRRKRSTREEVFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFAQSKPDSAEPMNR
SAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTE
FTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSSTPHVNF
RLDSHPVSSEAIVEHPLNQNGYTLVVTGKKVTKIPLNGLGCEHFQSCSQCLSAPPFVQCG
WCHDKCVQLEECPSGTWTQEICLPTIYEVFPTSAPLEGGTMLTVCGWDFGFRRNNKFDLK
KTRVFLGNESCTLTLSESTTNMLKCTVGPAVNEHFNISIIISNGRGTAQYSTFSYVDPVI
TSIFPSYGPKTGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSDSILECYTPAQTIPTE
FPIKLKIDLANREMNSFSYQEDPIVYAIHPTKSFISGGSTITAVGKNLNSVSVLRMVISV
HETRRNFTVACHHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNP
VFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCETIYSDSEAVLCKVPND
LLKLNNELNIEWKQAVSSTILGKVIVQPDQNFTGLIVGVISISIILLLLLGVFLWLKKRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNG
SCRQVQYPLTDLSPMLNSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKK
FVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNIDGEG
DT
NT seq
4149 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcccctgctgtgcttgcacctggcatccttgtgcttctgtttaccttggtgcag
aagagctatggggagtgcagagaggcactagtaaagtctgagatgaatgtgaacatgaag
taccagcttcccaacttcactgcagaaacacccatccagaatgttgttttacacaagcat
catatttaccttggtgcagttaactatatttacgttttaaatgacaaagaccttcagaag
gttgctgagtacaagactgggcccgtgctggaacacccagattgtttcccatgtcaggac
tgcagccacaaagccaatttatcaggtggtgtttggaaagataacatcaacatggctcta
cttattgacacgtactatgacgaccaactcattagctgtggcagtgtccacagagggacc
tgccagcgacatgtccttccacccagcaatactgctgacatactgtcaaaagttcattgc
atgtactccccacaggcagacgaagagtccagccactgtcctgactgtgtggtgagtgcc
ctgggaaccaaagtcctgatatctgaaaagggccggttcatcaacttcttcgtgggcaat
accataaattcctcttacctaacagatcattcattgcattcaatatcagtgagaaggcta
aaggaaactcaagatggctttaagtttttaacagaccagtcttatattgatgttctccct
gaattcagagattcctaccctattaaatacatccatgcctttgaaagcaaccgttttatt
tactttttgacagtccagcgagaaactctagatgctcagacttttcacacaagaataatc
aggttctgttctgtagactctggattgcattcctacatggaaatgcctctggaatgtatc
ctcacagaaaagagaagaaagagatccacaagggaggaagtgtttaatattctccaagct
gcatatgtcagtaagcctggggcccaccttgctaagcaaataggtgccaacctgaatgat
gacattctctatggagtattcgcacaaagcaagccggattctgctgaaccaatgaatcgc
tctgctgtctgtgcattccctatcaaatatgtcaatgaattcttcaacaagattgtaaac
aaaaacaacgtgagatgtcttcaacatttttatggacccaaccacgaacactgctttaat
aggacacttttgagaaattcatcaggctgtgaagtgcgcagtgatgaatatcgaacggag
tttaccacagctttgcagcgagttgacttattcatgggccaattcaaccaagtcctctta
acatctatatccaccttcattaaaggagacctcaccattgctaatcttgggacgtcagag
ggtcgctttatgcaggttgtggtttctcgatcaggatcatcaacccctcatgtgaatttt
cgcctggattcccaccctgtgtcttcagaagcaattgtggagcacccattaaaccaaaat
ggctacacactggttgttactggaaagaaggtcaccaagatcccactgaatggcttaggc
tgtgaacatttccagtcctgcagtcagtgtctttctgcccctccctttgtgcaatgtggc
tggtgccacgacaaatgtgtgcaactggaggaatgccccagtggaacatggactcaagag
atctgtctgcctacaatctatgaggttttcccaaccagtgcacccctggaaggaggaaca
atgctcactgtgtgtggctgggactttggattcaggaggaataataaatttgatttaaag
aaaactagagttttccttggaaatgagagctgcactttgaccttaagtgagagcacaaca
aatatgttgaaatgcacagttggtcctgcagtgaatgagcatttcaatatatccataatt
atttcaaatgggcgagggacagcacaatacagtacattttcctatgtggatcctgtaata
acaagtatttttccaagttatggtcctaagactggtggcaccttgcttactttaactgga
aagtaccttaacagtgggaattctagacacatttcaattggtggaaaaacgtgtacttta
aaaagtgtgtcagatagtattctcgaatgttataccccagctcaaaccattccaactgag
tttcctattaaattgaaaattgacttagccaaccgagagatgaacagtttcagttaccag
gaagaccccattgtctatgcaattcatccaaccaaatcttttattagtggtgggagcacc
ataacagctgttgggaaaaacctgaattcagttagtgtcctaaggatggtaataagtgta
catgaaacaagaaggaactttacagtggcatgtcaccatcgctctaattcagagataatc
tgctgtacaactccttcactgcaacagctgaatctgcaactccctctgaaaaccaaagcc
tttttcatgttagatgggatccattccaaatactttgatctcatttatgtacataatcct
gtgtttaagccttttgaaaagccagtgatgatctcaataggcaatgaaaatgtactggaa
attaagggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaat
aagagctgtgagactatatactcagattctgaagctgttttatgcaaggtccccaatgac
ctgctgaaattgaacaacgagctaaatatagagtggaagcaagcagtttcttcaaccatc
cttggaaaagtaatagttcaaccagatcagaatttcacaggattgattgttggtgttatc
tcaatatcaataatactcttactattacttggggttttcctgtggctgaaaaagagaaag
caaattaaagatctgggcagtgaattagttcgctatgatgcaagagtacacactcctcat
ttggataggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaa
tctgtagactaccgagctacttttccagaagaccagtttcctaactcatctcagaatgga
tcgtgcagacaagtacagtatcctctgacggacctgtcccccatgcttaatagtggggac
tctgatatatccagtccattactgcaaaatactgtccacattgacctcagtgctctaaat
ccagagctggtccaggcagtccagcacgtagtgattgggccaagtagcctgattgtgcat
ttcaatgaagtcataggaagaggacattttgggtgtgtgtaccatgggactttattggac
agcgatgacaagaagattcactgtgctgtgaaatccttgaatagaatcactgacataggt
gaagtttcccagtttctgactgagggaatcatcatgaaagattttagtcatccaaatgtt
ctctcactcttgggaatctgccttcgaagtgaggggtctccactggtggtcctaccatat
atgaaacatggagatcttcgaaatttcatcagaaatgagactcataacccaactgtaaaa
gatcttattggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaag
tttgtacacagagacttggctgctagaaactgtatgctggatgaaaaattcactgtcaag
gttgctgattttggtctggccagagacatgtatgataaagagtactacagtgtacacaac
aaaacgggcgccaagctgccagtgaagtggatggctctagaaagtctacaaactcagaag
tttaccaccaagtcagatgtgtggtcctttggtgtactcctctgggaactgatgacaaga
ggggctccaccttatcctgatgtcaacaccttcgatataacagtttacttattgcaaggc
agaagactcttacagcccgaatactgcccagatcccttatatgaagtgatgctaaaatgc
tggcaccctaaagccgaactgcgcccatctttttctgaactggtctccaggatatcagcg
atattctctactttcattggggagcactatgtccatgtgaacgctacttatgtgaatgtc
aaatgtgttgctccatacccttctctgttgtcatcacaagataacattgatggcgagggg
gacacatga
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integrated database retrieval system
