Panthera leo (lion): 122211393 Help Entry 122211393         CDS       T10741                                  Symbol PTGS2 Name (RefSeq) prostaglandin G/H synthase 2   KO K11987   prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1] Organism plez  Panthera leo (lion) Pathway plez00590   Arachidonic acid metabolism plez01100   Metabolic pathways plez04064   NF-kappa B signaling pathway plez04148   Efferocytosis plez04370   VEGF signaling pathway plez04625   C-type lectin receptor signaling pathway plez04657   IL-17 signaling pathway plez04668   TNF signaling pathway plez04723   Retrograde endocannabinoid signaling plez04726   Serotonergic synapse plez04913   Ovarian steroidogenesis plez04921   Oxytocin signaling pathway plez04923   Regulation of lipolysis in adipocytes plez05010   Alzheimer disease plez05022   Pathways of neurodegeneration - multiple diseases plez05140   Leishmaniasis plez05163   Human cytomegalovirus infection plez05165   Human papillomavirus infection plez05167   Kaposi sarcoma-associated herpesvirus infection plez05200   Pathways in cancer plez05204   Chemical carcinogenesis - DNA adducts plez05206   MicroRNAs in cancer plez05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:plez00001]  09100 Metabolism   09103 Lipid metabolism    00590 Arachidonic acid metabolism     122211393 (PTGS2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     122211393 (PTGS2)    04064 NF-kappa B signaling pathway     122211393 (PTGS2)    04668 TNF signaling pathway     122211393 (PTGS2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     122211393 (PTGS2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     122211393 (PTGS2)    04657 IL-17 signaling pathway     122211393 (PTGS2)   09152 Endocrine system    04923 Regulation of lipolysis in adipocytes     122211393 (PTGS2)    04913 Ovarian steroidogenesis     122211393 (PTGS2)    04921 Oxytocin signaling pathway     122211393 (PTGS2)   09156 Nervous system    04726 Serotonergic synapse     122211393 (PTGS2)    04723 Retrograde endocannabinoid signaling     122211393 (PTGS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122211393 (PTGS2)    05206 MicroRNAs in cancer     122211393 (PTGS2)    05204 Chemical carcinogenesis - DNA adducts     122211393 (PTGS2)   09162 Cancer: specific types    05222 Small cell lung cancer     122211393 (PTGS2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     122211393 (PTGS2)    05167 Kaposi sarcoma-associated herpesvirus infection     122211393 (PTGS2)    05165 Human papillomavirus infection     122211393 (PTGS2)   09174 Infectious disease: parasitic    05140 Leishmaniasis     122211393 (PTGS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     122211393 (PTGS2)    05022 Pathways of neurodegeneration - multiple diseases     122211393 (PTGS2) Enzymes [BR:plez01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.99  Miscellaneous     1.14.99.1  prostaglandin-endoperoxide synthase      122211393 (PTGS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  An_peroxidase EGF Motif Other DBs NCBI-GeneID:  122211393 NCBI-ProteinID:  XP_042780400 UniProt:  A0A8C8Y2B4 LinkDB All DBs Position F3:22186175..22199738 Genome browser AA seq 604 aa AA seqDB search MLARALLLCAALALCRAANPCCSNPCQNQGVCLSIGFDQYKCDCTRTGFYGENCSTPEFL TRIKLFLKPTPNTVHYILTHFKGVWNIVNNIPFLQNIIMKYVLTSRSHLIESPPTYNVDY GYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGT NMMFAFFAQHFTHQFFKTDHKRGPAFTKGLGHGVDLSHVYGETLDRQHKLRLFKDGKMKY QIIDGEVYPPTVKDTQVEMIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCD VLKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQ NRIAAEFNTLYHWHPLLPDTLQIDDQEYNFQQFVYNNSILLEHGLTQFVESFSRQIAGRV AGGRNVPAAVQQVAKASIDQSRQMKYQSLNEYRKRFRLKPYTSFEELTGEKEMAAGLEAL YGDIDAMELYPALLVEKPRPDAIFGETMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGEV GFKIINTASIQSLICNNVKGCPFTAFSVQDPQLTKTVTINASSSHSGLDEINPTVLLKER STEL NT seq 1815 nt NT seq  +upstreamnt  +downstreamnt atgcttgcccgcgccctgctgctctgcgccgccctggcgctctgccgtgcagcaaatcct tgctgttccaacccatgccaaaaccaaggtgtatgtctgagcataggatttgaccagtat aagtgtgactgtacccgaacaggattctatggtgaaaactgttcaacacctgaatttctg acaagaataaagttattcctgaaacccactccaaatacagtgcactacatacttacccac ttcaagggagtctggaacattgtcaataacattcccttcctgcaaaatataattatgaaa tatgtgttgacatccaggtcacatttgattgagagcccaccaacttacaatgtggactat ggctataaaagctgggaagccttttccaatctctcctattataccagagctcttccccct gtggctgatgactgcccaacacccatgggtgtgaaaggcaagaaagagcttcctgattca aaagagattgtggaaaaatttcttctaagaagaaagttcattcctgacccccaaggcaca aatatgatgtttgcattttttgcccaacacttcacccatcaatttttcaagacagatcat aagcgaggaccagctttcaccaaaggactgggccatggggtggacttaagtcatgtttat ggggaaactttggatagacagcataaactgcgccttttcaaggatggaaaaatgaaatac cagataatcgatggggaggtgtatcctcccacagtcaaagatactcaggtcgagatgatc tacccacctcatgttcctgaacacctgcggtttgctgtgggccaggaggtctttggtctg gtgcctggtctgatgatgtacgccacaatttggctgcgggaacacaacagagtgtgtgat gtgcttaaacaggagcatccagaatgggatgatgagcggttgttccagacgagcaggcta atactgataggagaaaccattaagatcgtgattgaagactatgtacaacacttgagtggc tatcacttcaaactgaagtttgacccagagctgcttttcaaccaacaattccaataccaa aaccgtattgctgctgagtttaacacactctaccactggcatccccttctgcctgacacc ttgcaaatagatgaccaggagtacaatttccagcagtttgtctacaacaactctatatta ctggaacatgggcttacccagttcgtggaatcattcagcaggcaaattgctggcagggtt gctggtggtaggaatgttccagctgcagtgcagcaagtagcaaaggcctcaatcgaccag agcagacagatgaagtaccagtctcttaatgagtatcgcaaacgctttcggctgaagccc tatacatcgtttgaagaactcacaggagagaaggaaatggctgcggggttagaagcactt tatggtgatattgatgccatggagctgtatcctgcccttctggtagaaaagcctcgccct gatgccatctttggtgagaccatggtagaaatgggagcaccattctccttgaaaggactt atgggtaatcctatatgctctcctgactactggaagcctagcacttttggtggagaagta ggttttaaaatcatcaacactgcctcgattcagtctctcatctgcaataacgtgaagggc tgtccttttactgcattcagtgttcaagatccacagctcaccaaaacagtcaccattaat gcaagctcttcgcactctggactggatgaaatcaatcccacagtactgctaaaagaacgt tcaactgaactgtag

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