Panthera leo (lion): 122211942
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Entry
122211942 CDS
T10741
Symbol
NTRK1
Name
(RefSeq) high affinity nerve growth factor receptor
KO
K03176
neurotrophic tyrosine kinase receptor type 1 [EC:
2.7.10.1
]
Organism
plez Panthera leo (lion)
Pathway
plez04010
MAPK signaling pathway
plez04014
Ras signaling pathway
plez04020
Calcium signaling pathway
plez04151
PI3K-Akt signaling pathway
plez04210
Apoptosis
plez04722
Neurotrophin signaling pathway
plez04750
Inflammatory mediator regulation of TRP channels
plez05200
Pathways in cancer
plez05202
Transcriptional misregulation in cancer
plez05216
Thyroid cancer
plez05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122211942 (NTRK1)
04014 Ras signaling pathway
122211942 (NTRK1)
04020 Calcium signaling pathway
122211942 (NTRK1)
04151 PI3K-Akt signaling pathway
122211942 (NTRK1)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
122211942 (NTRK1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
122211942 (NTRK1)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
122211942 (NTRK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122211942 (NTRK1)
05202 Transcriptional misregulation in cancer
122211942 (NTRK1)
05230 Central carbon metabolism in cancer
122211942 (NTRK1)
09162 Cancer: specific types
05216 Thyroid cancer
122211942 (NTRK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122211942 (NTRK1)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122211942 (NTRK1)
Protein kinases [BR:
plez01001
]
Receptor tyrosine kinases (RTK)
TRK family [OT]
122211942 (NTRK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
LRR_8
I-set
LRRCT_2
Ig_3
TrkA_TMD
LRR_NXF1-5
LRR_4
Motif
Other DBs
NCBI-GeneID:
122211942
NCBI-ProteinID:
XP_042781431
LinkDB
All DBs
Position
F3:complement(66946313..66965254)
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AA seq
795 aa
AA seq
DB search
MLRGGRGPRGGHGRAAGPGSLLAWLMLASAGAAPCADVCCPHGPSGLRCTRAGALESLRR
LPGAENLTELYIENQERLRHLEPSDLRGLGELRGLAIVKSGLRFVAPDAFHFTPRLSRLN
LSFNALESLSWKTVQGLSLQELVLSGNPLRCSCALHWLLRWEEEGLGGVPAQRLQCPGQG
PLALLSNASCGVPVLKVQTPNASVNVGDDVLLQCQVEGRGLEQAGWILTELEESATVTQS
GALPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSFPASVQLHAAVELHHWCI
PFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNGNYTL
LAANPSGRAAASVLAAFMDNPFEFNPEDPIPVSFSPVDSNSTSGDPVEKKDETPFGVSVA
VGLAVFACLLLSAFFLVLNKCGRRNKFGINRTAVLAPEDGLAMSLHFMTLGGSSLSPTEG
KGSGLQGHIIENPQYFGDACVHHIKRRDIVLKWELGEGAFGKVFLAECYNLLPEQDKMLV
AVKALKEVSESARQDFQREAQLLTVLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFL
RSHGPDAKLLAGREDVAPGPLGLSQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQG
LVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIF
TYGKQPWYQLSNTEAIECITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKEVHARL
QALAQAPPVYLDVLG
NT seq
2388 nt
NT seq
+upstream
nt +downstream
nt
atgctgcgaggcggacgcgggccgcggggcgggcacggccgggccgcggggccgggcagc
ctgctggcctggctgatgctggcgtccgcgggcgccgcaccctgcgcggacgtctgctgc
ccccacggcccctcggggctgcgctgcacccgggctggggccctggagagcctccgccgc
ctgccgggcgctgagaacctgacggagctctacatcgagaaccaagagcggctgcggcat
ctggagcccagtgacctgaggggcctgggggagctgagaggcctcgccatcgtgaagagc
gggctccgtttcgtggcaccagatgccttccattttactcctcggctcagtcgcctgaat
ctctcctttaacgctttggagtctctctcctggaaaaccgtccagggcctgtcgctgcag
gagctggtcctgtcggggaaccctctgcgctgttcttgtgccctgcactggctgctgcgc
tgggaggaggagggcctgggcggagttcctgcacagaggctgcagtgtcccgggcagggg
cccctggccctcttgtccaacgccagctgtggcgtgcccgtgctgaaggtccagacgccc
aatgcctccgtgaacgtgggggacgatgtgttgctacaatgccaggtggaggggcggggc
ctggagcaagctggctggatcctcacggagctggaggagtcggccacggtgacgcaatct
ggggctctgccatccctggggctgaccctggccaatgtcaccagtgacctcaacaggaag
aatgtgacatgctgggcggagaatgatgtgggccgggctgaagtctccgtgcaggtcaac
gtgtccttcccggccagtgtgcagctgcatgccgccgtagagctgcaccactggtgcatc
cccttctcggtggacgggcagccggcgccctccctgcgctggctcttcaacggctcggtg
ctcaacgagacgagcttcatcttcacggagttcctggagccggcggccaacgagaccgtg
cggcacggctgcctgcgcctcaaccagcccacccacgtcaacaacggcaactacacgctg
ctggccgccaacccctctggccgggccgccgcctccgtgctggcggccttcatggacaac
ccgttcgagttcaaccccgaagaccccatccccgtctccttctcgccggtggactcgaac
agcacgtccggagacccagtggagaaaaaggacgaaaccccttttggggtctcagtggcc
gtgggcttggccgtctttgcctgcctcctcctctccgccttcttccttgtgctcaacaaa
tgtggacggaggaacaagtttgggatcaaccgcacagctgtgctggctccagaggacgga
ctggccatgtccctgcatttcatgacattaggtggcagctccttgtcccccactgagggc
aaaggctctgggctccaaggccacatcattgagaacccacaatacttcggtgatgcctgt
gttcaccacatcaagcgcagggacatcgtgctcaagtgggagctgggcgagggcgccttc
gggaaggtcttcctggccgaatgctacaacctgctgcccgagcaggacaagatgctggtg
gccgtcaaggcgctgaaggaggtgtccgagagcgccaggcaggacttccagcgggaggcc
cagctgctcaccgtgctccagcaccagcacatcgtgcgcttcttcggggtctgcaccgag
ggccgcccgctgctcatggtctttgagtacatgcgccacggcgacctcaaccgcttcctc
cggtcccacgggcccgacgccaagctgctggctggcagggaggacgtggctccgggcccc
ctgggcctgtcccagctgctggccgtggctagccaggtcgctgccgggatggtgtacctg
gcgggtctgcacttcgtgcatcgggacctggccacgcgcaactgtctggtgggtcagggg
ctggtggtcaagatcggcgacttcggcatgagcagggacatctacagcaccgactattac
cgagtggggggccgcaccatgctccccatccgctggatgccccccgagagcatcctctac
cgcaagttcaccaccgagagcgacgtgtggagcttcggcgtggtgctctgggagatcttc
acctacggcaaacagccctggtaccagctctccaacaccgaggcgatcgagtgcatcacg
caggggcgcgagctggagcggccccgggcctgcccaccggaggtctacgccatcatgcgg
ggctgctggcagcgggagccacagcaacgccacagcatcaaggaggtgcacgcccggctg
caggccctggcccaggcgcctcctgtctacttggacgtcctgggctag
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