Panthera leo (lion): 122212148
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Entry
122212148 CDS
T10741
Symbol
FH
Name
(RefSeq) fumarate hydratase, mitochondrial
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
plez Panthera leo (lion)
Pathway
plez00020
Citrate cycle (TCA cycle)
plez00620
Pyruvate metabolism
plez01100
Metabolic pathways
plez01200
Carbon metabolism
plez04934
Cushing syndrome
plez05200
Pathways in cancer
plez05211
Renal cell carcinoma
Module
plez_M00009
Citrate cycle (TCA cycle, Krebs cycle)
plez_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
Enzymes [BR:
plez01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
122212148 (FH)
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NCBI-GeneID:
122212148
NCBI-ProteinID:
XP_042781790
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Position
F3:8776184..8806716
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AA seq
508 aa
AA seq
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MYRVVRLLARSRRLVRPPGSASAPGLGGVPVLPLRAPNAAGMASQNSFRIEFDTFGELKV
PNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDSKIANAIMK
AADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVN
KSQSSNDTFPTAMHIAAAVEVHEVLLPGLQKLHDALEAKSKEFAQIIKIGRTHTQDAVPL
TLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTG
LPFVTAANKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENE
PGSSIMPGKVNPTQCEALTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARL
LGDACVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTL
KATAIELGYLTAEQFDEWVKPKDMLGPK
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgcgtcgtccgactcctcgcgcgctcgcgtcgcctcgtgcggcctcccggctca
gcctcagctcccggcctcggaggcgtgccggtcctcccactgcgggccccgaacgccgct
ggaatggcaagccaaaattcctttcggatagagtttgatacttttggtgaactcaaggtc
ccaaatgataagtattatggcgcccagactgtgagatccacgatgaactttaaaattgga
ggtgtgacggagcgcatgccaatcccagttattaaagcttttggaatcttgaagcgagcg
gctgctgaagtaaaccaggattatggtcttgattcgaagattgctaatgcgataatgaag
gcagccgatgaggtagctgaaggtaaattaaatgatcattttccacttgtggtatggcag
actggatcaggaacccagacaaatatgaatgtaaatgaagtcattagcaatagagcaatt
gaaatgctgggaggtgaacttggtagcaagaaacctgtgcatcccaatgatcacgttaat
aaaagccagagttcgaatgatacctttcccacagcgatgcacattgctgctgctgtagaa
gttcatgaggtgctcctgccagggctacagaagctgcatgatgctctcgaagccaaatcc
aaagagtttgcccagatcatcaaaattgggcgcactcacacccaggacgctgttccactc
actcttgggcaggaatttagtggttatgttcaacaagtgaaatatgcaatgacgagaata
aaagccgccatgccaagaatctatgagctcgcagctggaggcactgctgttggtactggt
ttaaatactagaattggctttgcagaaaaggttgctgcaaaagtggctgcactcacaggg
ttgccttttgtcacagctgcaaataaatttgaagctctggctgctcatgatgctttggtt
gaactcagtggagccatgaatactaccgcctgcagtctgatgaagatagcaaacgatatt
cgttttctgggttctggtcctcgctcaggtctgggagagctgatcttgcctgaaaatgag
ccaggaagtagtatcatgccaggcaaggtgaaccctacgcagtgtgaagcgctcaccatg
gttgcagcccaggtcatggggaatcacgtcgccgttaccgttggaggcagcaatggacat
tttgagttgaatgttttcaagccaatgatgattaaaaatgtgttacactcagccaggctg
ctgggggacgcgtgcgtttccttcacagaaaactgcgttgtgggaatccaggccaacaca
gagaggatcaacaagctgatgaacgaatctctaatgttggtgacagctcttaatcctcat
atagggtatgacaaggcagcaaagattgctaagacagcacacaaaaatggatcaacctta
aaggccactgccattgagcttggctatctcacagcagagcagtttgatgagtgggtaaaa
cctaaggacatgctgggtccaaagtga
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