Panthera leo (lion): 122212384
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Entry
122212384 CDS
T10741
Symbol
ATP2B4
Name
(RefSeq) plasma membrane calcium-transporting ATPase 4 isoform X1
KO
K05850
P-type Ca2+ transporter type 2B [EC:
7.2.2.10
]
Organism
plez Panthera leo (lion)
Pathway
plez04020
Calcium signaling pathway
plez04022
cGMP-PKG signaling pathway
plez04024
cAMP signaling pathway
plez04261
Adrenergic signaling in cardiomyocytes
plez04925
Aldosterone synthesis and secretion
plez04961
Endocrine and other factor-regulated calcium reabsorption
plez04970
Salivary secretion
plez04972
Pancreatic secretion
plez04978
Mineral absorption
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
122212384 (ATP2B4)
04024 cAMP signaling pathway
122212384 (ATP2B4)
04022 cGMP-PKG signaling pathway
122212384 (ATP2B4)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
122212384 (ATP2B4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
122212384 (ATP2B4)
09154 Digestive system
04970 Salivary secretion
122212384 (ATP2B4)
04972 Pancreatic secretion
122212384 (ATP2B4)
04978 Mineral absorption
122212384 (ATP2B4)
09155 Excretory system
04961 Endocrine and other factor-regulated calcium reabsorption
122212384 (ATP2B4)
Enzymes [BR:
plez01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
122212384 (ATP2B4)
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Gene cluster
GFIT
Motif
Pfam:
Cation_ATPase_C
Cation_ATPase
ATP_Ca_trans_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
Motif
Other DBs
NCBI-GeneID:
122212384
NCBI-ProteinID:
XP_042782171
UniProt:
A0A8C9DBI8
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Position
F3:42263201..42361572
Genome browser
AA seq
1207 aa
AA seq
DB search
MTNPTERTLPANSMVESHEREFGCTVMDLRKLMELRSTDAINQINVHYGGVTNLCSRLKT
NPVEGLSGNPADLEKRKHVFGQNFIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS
FYRPPGEENEQCGLPVSSPEDEGEAEAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL
QNRIEKEQKFSVIRNGHIIQLPVAEIVVGDIAQIKYGDLLPADGILIQGNDLKIDESSLT
GESDHVKKSVERDPMLLSGTHVMEGSGRMVVTAVGINSQTGIIFTLLGASEGEEEEKKKK
GKKQGVPENRNKAKTQDGVALEIQPLNSQEGTDNEEKEKKAAKLPKKEKSVLQGKLTRLA
VQIGKAGLIMSAFTVLILILYFVIDNFVIHRRAWLPECTPIYIQYFVKFFIIGITVLVVA
VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA
YIGDTHYHQIPSPDVLLPKVLDLIVNAISINSAYTSKILPPEKEGGLPRQVGSKTECALL
GFVTDLKQDYHAVRNEVPEEKLYKVYTFNSVRKSMSTVIEKPSGGYRMYSKGASEIILRK
CNRILDKKGEVVPFKSKDRDEIVRTVIEPMACEGLRTICIAYRDFNDGEPPWDNESEILT
ELTCVAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGIVTPGDDFL
CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTIGEQRQVV
AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI
SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL
KRRPYGRNKPLISRTMMKNILGHAVYQLTVIFFLVFAGEKFFDIDSGRKAPLHSPPSQHY
TIIFNTFVLMQLFNEINSRKIHGERNVFAGIFRNLIFCCVVLGTFISQILIVEFGGKPFS
CTKLTLSQWFWCLFIGIGELLWGQIISSIPTQSLKFLKEAGHGTTKEEITKDAEGLDEID
HAEMELRRGQILWFRGLNRIQTQIKVVKAFHSSLHESIQKPKNQNSIHNFMTHPEFAIDE
EVPRTPLLDEHEEEDLEQAPKAGTGVLLLDGEVTPYANKNNNAVDCSQVHIVASHADSPL
HSLETSV
NT seq
3624 nt
NT seq
+upstream
nt +downstream
nt
atgacgaacccaacagaacgtaccttgccggccaactcgatggttgagagccacgagcgg
gagtttggctgcacagtaatggacctgcggaagctcatggagctacgttcgaccgacgca
atcaaccagatcaacgtccactacgggggtgtaacgaatctctgcagtagactgaaaacc
aaccccgtggaaggtctgtctgggaaccctgcggacctggagaaacgtaagcacgtgttc
ggacagaactttatcccccccaaaaagcccaagaccttcttagaactagtgtgggaagcc
cttcaagatgtcacactcatcatcctggagattgcagccatcatctccctcgtcctgtcc
ttctatcggccccccggtgaagaaaatgaacagtgtggtctacccgtaagtagcccggaa
gacgaaggagaggcagaagccggctggattgagggggcagccatcctgttctccgtgatc
atcgtggtgctggtgactgccttcaatgattggagcaaagagaagcaattccgggggctg
cagaaccgcatcgaaaaggaacagaaattctccgtgatccgaaatggtcacatcatccag
ctcccagtggctgagatcgtggtgggtgacatcgcccaaatcaaatacggtgacctactg
cccgcagatgggatcctgatccaggggaacgatctcaagattgacgagagctctctgact
ggggaatcagaccatgtcaagaagtctgtggaaagggacccaatgctgctctcagggacc
catgtcatggaaggttctggccggatggtagtgacggctgtgggtatcaactctcagact
ggaatcatctttacccttttgggagccagcgagggagaagaggaggagaagaagaaaaaa
ggtaaaaaacaaggagtccctgaaaatcgcaacaaagcaaaaactcaggatggggtggcc
ctggaaatccagccactcaacagccaggaggggaccgacaacgaggagaaggagaagaag
gcggccaagctgcccaaaaaggagaagtcggtgctgcagggcaagctgacgcgcttggct
gttcagatcgggaaagctggcctcatcatgtctgccttcacggttctcatcctgatcctg
tactttgtgattgacaacttcgtgatccaccgcagagcgtggctgcccgagtgcactccc
atctacatccagtactttgtcaagttcttcatcatcggcatcactgtgctggtggtggct
gtgccagaggggctgccgctggctgtcaccatttccctggcctactccgtgaagaaaatg
atgaaagacaataacctggtgcggcacctggatgcttgtgagacaatgggcaacgccaca
gccatttgctctgataagaccggcacgttgaccatgaaccgcatgaccgtggtacaggct
tatattggagacacccattaccatcagatcccgagccctgatgtcctcctgcccaaggtc
ctggaccttattgtcaatgccatttctatcaacagtgcctatacctccaagattctgcct
ccggagaaggagggaggtctgccgcggcaggtgggcagcaagaccgaatgtgctctgctg
ggctttgtcacagacctgaagcaggattaccatgcggtgcgcaatgaggtgcccgaggag
aagctctacaaggtgtataccttcaactcggtgcgcaaatccatgagcacggtcatcgag
aagcccagcgggggctaccgcatgtacagcaagggcgcctcggagatcatcttgcgcaag
tgcaaccgaatcctggacaagaaaggggaagtggtgccattcaagagcaaggaccgagat
gagatagtgcgcactgtcatcgagcccatggcctgcgagggcctccgaactatctgcata
gcttaccgggatttcaatgacggagagcccccgtgggacaacgagagtgagatcctcacc
gaactgacctgcgtcgcggtggtgggcattgaggaccccgtgcgcccagaggtcccagac
gctatcgccaaatgcaaacaagctggcatcactgtcagaatggtgaccggtgacaacatc
aacacagcccgggccatcgccaccaaatgtggcattgtcacacctggggatgacttcttg
tgcttagaaggcaaagagttcaaccgacttatccgcaacgagaagggcgaggtagagcaa
gagaagctggacaagatctggcctaagcttcgagtcttggcgcgatcgtcccccactgac
aagcacaccctggtaaaaggcatcatcgacagcactattggggaacagcgacaggtggtg
gctgtcactggcgacggcacgaatgatgggccggccctgaagaaagcagatgttggcttt
gccatgggtattgcaggcacggatgtggcaaaggaggcatcagacatcatcctaacagac
gacaacttcaccagcattgtgaaggcagtgatgtgggggcgaaacgtctatgacagcatc
tccaagtttctgcagttccagctcactgtcaacgtggtggccgtgattgtggccttcacc
ggagcctgtatcactcaggattccccactgaaagccgtgcagatgttgtgggttaaccta
atcatggacacttttgcctccttggccctggccaccgagcctcctacggagtctctgttg
aagcgtcgcccctatggccgcaataagcctctgatctcacgtactatgatgaagaacatc
ttgggccacgcagtctatcagctcactgtcatctttttccttgtctttgccggtgagaaa
ttctttgacatcgatagcgggaggaaggcgcctctacattccccacccagccaacactac
accattattttcaacacctttgtgctgatgcagctcttcaacgaaatcaactctcgcaag
atccacggagagaggaatgtctttgcaggcatcttccgcaacctcatcttctgctgtgtg
gtcttgggcacgttcatcagccagattctcattgtggaattcgggggtaaacccttcagt
tgcacgaagctcaccctgtctcagtggttttggtgtctcttcattggcatcggagaactg
ctgtggggccagataatctcctcgatacctacgcaatccctgaagttcctgaaggaggcc
gggcatggcaccacgaaagaggagatcaccaaggacgcggaggggctggatgagattgac
cacgcggagatggagctgcgccgaggccagatcctctggttccggggcctgaaccgcatc
cagactcagatcaaagtggtcaaagcgttccatagttccctccacgaaagcattcagaaa
cccaagaaccaaaactccatccacaacttcatgacccaccctgaattcgccatagatgag
gaggtgccacgaacaccactcctggatgagcatgaggaggaagatctcgaacaggctcct
aaggctgggactggggtgctcctgttggatggtgaggtcaccccatatgccaacaagaac
aacaatgcggtggactgcagccaagtgcacatcgttgcctcccatgcggacagccctcta
cacagcctggagacatcagtttga
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