Panthera leo (lion): 122213942
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Entry
122213942 CDS
T10741
Symbol
DNMT1
Name
(RefSeq) DNA (cytosine-5)-methyltransferase 1 isoform X1
KO
K00558
DNA (cytosine-5)-methyltransferase 1 [EC:
2.1.1.37
]
Organism
plez Panthera leo (lion)
Pathway
plez00270
Cysteine and methionine metabolism
plez01100
Metabolic pathways
plez05206
MicroRNAs in cancer
Module
plez_M00035
Methionine degradation
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
122213942 (DNMT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
122213942 (DNMT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
plez03000
]
122213942 (DNMT1)
03032 DNA replication proteins [BR:
plez03032
]
122213942 (DNMT1)
03036 Chromosome and associated proteins [BR:
plez03036
]
122213942 (DNMT1)
09183 Protein families: signaling and cellular processes
02048 Prokaryotic defense system [BR:
plez02048
]
122213942 (DNMT1)
Enzymes [BR:
plez01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.37 DNA (cytosine-5-)-methyltransferase
122213942 (DNMT1)
Transcription factors [BR:
plez03000
]
Eukaryotic type
Zinc finger
CXXC CpG-binding proteins
122213942 (DNMT1)
DNA replication proteins [BR:
plez03032
]
Eukaryotic type
DNA Replication Termination Factors
DNA methylation enzymes
122213942 (DNMT1)
Chromosome and associated proteins [BR:
plez03036
]
Eukaryotic type
Heterochromatin formation proteins
Other heterochromatin formation proteins
122213942 (DNMT1)
Prokaryotic defense system [BR:
plez02048
]
Restriction and modification system (R-M system)
Type II R-M system
DNA methyltransferases
122213942 (DNMT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BAH
DNA_methylase
DNMT1-RFD
DMAP_binding
zf-CXXC
Motif
Other DBs
NCBI-GeneID:
122213942
NCBI-ProteinID:
XP_042784307
LinkDB
All DBs
Position
A2:complement(7623883..7671074)
Genome browser
AA seq
1716 aa
AA seq
DB search
MAASRDRRRRSGPGRGRLSPENLHPLEHESREPRPGLNTSAGFVSLVEPLPDFPVPVSYG
RAWPVGWGLLELESSLEWVLQEFIKRKQGFLLMSAFCQNRSFQLGSLNRPLAWGLSWASA
SAWLNLNALRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLHKEELSEEG
YLAKVKSLLNKDLSLENGAHALSREVNGCLENGSQTSGEDRRVGMAEENKSPKPVSKLYT
PRRSKSDGETKSEVSSSPRITRQTTRQTTILSHFSRGPAKRKPEEEREKAKSDDHVEEEK
DQEEKRRRVTSREQVARPLPAEEPERVGPGTHMEEEEERDEKEEKRLRSQTKEPTPKLKS
KEELDREGRTGVQAETDEGDERDERRPRSQPKDLAAKRRPEEKEPERVKPQVSEEKDEDE
KEEKRRKTTSKEPTEKKMARTKTVVSSKPNPLRCVQCGQYLDDAELKYEQHPPDAVDEPQ
LLTNERLSIFDANESGFESYEALPQHKLTCFSVYCKRGHLCPIDTGLIEKNVELFFSGSA
KPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPNPEYAPLF
SVMQEKIYISKIVVEFLQSNPDSTYEDLINKIETTVPPSVLNLNRFTEDSLLRHAQFVVE
QVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGKRRAERRQTIGHSAKEKDKGPTKATT
TKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSG
RSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQGKKKKQNKNRISWIGEAVKT
DGKKSYFKKVCIDSETLEVGDCVSVIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAG
TDTVLGATSDPLELFLVDECEDMQLSYIHSKVKVVYKAPSENWAMEGGMDPEPLMAEDDG
KTYFYQLWYDQDYARFESPPKTQPTEDNKYKFCVSCARLAEMRQKEIPRVMEQLEDLDSR
VLYGSATKNGIQYRVGDGVYLLPEAFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYI
KGSNLDAPEPYRIGRIKEIFCIKKSNGRPNETDIKIRINKFYRPENTHKSTPASYHADIN
LLYWSDEEVVVDFKAVQGRCTVEYGEDLPGGLQDFSAGGPDRFYFLEAYNAKNKSFEDPP
NHARSPGNKGKGKGKGKGKAKSQTCEPSEPETEIQLPKLRTLDVFSGCGGLSEGFHQAGI
SETLWAIEMWDPAAQAFRLNNPGSTVFTEDCNVLLKLVMAGEATNSRGQKLPQKGDVEML
CGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRYFLLENVRNFVSFKRSMVL
KLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQ
LSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEILYNGEPQSWFQRQL
RGSQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTYH
DKKNGCSSTGALRGVCSCVEAGKACDSAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWD
GFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAV
PPPLAKAIGLEIKRCMLAKARESASVKIKEEEATKD
NT seq
5151 nt
NT seq
+upstream
nt +downstream
nt
atggcggcctccagagacagacgtcgccgctcggggcccgggcgcggccggctcagtcct
gaaaacttgcaccccttggaacacgagtcccgggaacctcgcccaggcctgaacacttca
gccggatttgtgagcctggttgagcctttgcccgatttccctgtgccggtttcctatggt
cgtgcctggccagtcggatgggggcttttggagttggagagttctttagagtgggtgctg
caggagttcatcaagaggaagcaaggattcctgctgatgtctgctttttgccaaaaccgt
tcctttcagctagggtctttgaacaggccactggcttgggggttgtcttgggccagtgca
agtgcttggctgaatttgaatgctcttaggctcaaagatttggaaagagatagccttaca
gaaaaggaatgtgtgaaggagaaattgaatctcttgcatgaatttctgcaaacagaaata
aagaatcagttatgtgacttggaaaccaaattacataaagaagaattatcagaggagggc
tacctggctaaagtcaaatcccttttaaataaagatttatccttggagaatggagctcat
gctctcagtcgggaagtgaatggatgtctagaaaacgggagccagacaagtggtgaggac
cgcagagtgggaatggcagaggaaaacaaatcccccaagcctgtttccaaactttacaca
cccagaagaagcaaatcggacggagagacaaagtctgaagtttcatctagccccaggatt
acaaggcaaactaccaggcagaccaccatcctatctcatttctcaaggggccctgccaaa
cggaaacctgaggaagagcgtgaaaaagcgaaatcggatgatcatgttgaggaagaaaaa
gaccaggaggaaaagaggcggagagttacatccagagaacaagttgctagaccgctccct
gcagaagaaccggagagagtaggacctggaacacacatggaagaagaggaggaaagagac
gaaaaagaagaaaagaggctcagaagtcaaaccaaagaaccaacacctaaactgaagtcg
aaggaggagctggaccgagaaggaagaacaggagtgcaggccgaaacggatgaaggagac
gagagggatgaaaggagacccagaagtcaacccaaagatctagctgccaaacggagacct
gaagaaaaagaacctgaaagagtaaaaccacaagtttctgaagaaaaagatgaggatgaa
aaggaagagaagagacgcaaaactacatccaaagaaccaacggagaaaaaaatggctcga
accaaaaccgtggtgtcctccaagcccaatcctctgcggtgtgttcagtgtggacagtac
ctggacgatgccgagctaaagtacgaacagcatccccccgacgcagtggatgagccacag
ctgttgacaaacgagagactctccatcttcgatgccaacgagtctggcttcgagagttat
gaggcccttccccaacacaaactgacctgctttagcgtgtactgtaagcgtggtcacctg
tgcccgatcgacactggtctcattgaaaagaacgttgagctcttcttttccggttcagca
aaaccaatctacgatgatgacccgtctcttgaaggtggtgttaatggcaaaaatcttggc
cccataaatgaatggtggatcactggctttgatggaggtgaaaaggcgctcattggcttc
agcacctcttttgccgaatacattctgatggatcccaacccagagtacgcgccgctgttt
agtgtgatgcaggagaagatctacataagtaagattgtggttgagttcctgcagagcaac
ccagactccacctatgaagacttgatcaataagatcgagaccactgttcctccttctgtg
ctcaacctgaatcgattcacagaggattctctccttcggcacgcccagtttgtggtagaa
caagtagagagttatgatgaggctggggacagtgacgagcagcccatctttctgaccccc
tgcatgagggacctgatcaagttggctggggtcaccctaggaaaaaggcgagctgaaaga
cgtcagaccatcgggcattctgccaaagagaaggacaaaggccccactaaagccaccact
accaagctggtctaccagatctttgacactttcttcgcagagcaaatcgaaaaggatgac
cgagaagacaaggagaacgccttcaaacgccgacggtgtggcgtctgtgaggtgtgtcag
cagcccgaatgtggaaagtgtaaagcctgtaaagatatggttaagtttggtggtagcgga
cggagcaaacaggcttgccaagagaggaggtgtcccaatatggccatgaaggaggccgat
gacgatgaagaagttgacgacaatattccagagatgccgtcccccaaaaaaatgcatcag
gggaagaaaaagaaacagaacaagaatcggatctcttggattggagaagccgtcaagact
gatggaaagaagagttacttcaagaaggtgtgcattgactcagaaaccctggaagtgggg
gactgcgtctctgttattccagatgactcctccaaaccgctgtatttagccagagtcact
gcgctgtgggaggacagcagcaacgggcagatgtttcatgcccactggttctgcgcgggg
acagacacagtcctcggagccacgtcggaccccttggagctgttcctggtagacgaatgt
gaggacatgcagctttcgtacattcacagcaaggtgaaggtcgtctataaagctccgtca
gagaactgggccatggaggggggcatggatcctgagcctctgatggcggaggacgatgga
aagacctacttctaccagctgtggtatgatcaggactacgcaaggttcgagtcccctccg
aaaacccagccaacggaggacaacaagtacaagttctgtgtaagctgtgcccgtctggct
gaaatgaggcaaaaagagattcccagagtcatggaacagcttgaggacctggacagccgg
gttctctacggctcggccactaagaacggcatccagtatcgcgtcggggatggcgtatac
ctgctgcccgaggccttcacgttcaacatcaagctgtccagtcccgtgaagcgcccgcgg
aaggagcctgtggatgaagacctctaccccgaacactaccggaaatactccgattacatc
aaaggcagcaacctggatgcccccgagccgtatcgaattggccgaatcaaagaaatcttc
tgtatcaagaagagcaatggcaggcccaatgagaccgacatcaagatcagaatcaacaag
ttctacaggccagagaacacccacaagtctacgccggcgagttaccacgcggacatcaac
ctgctttactggagtgacgaggaggtggtggtggacttcaaggccgtgcagggccgctgt
accgtggagtacggggaggacctgccaggcggcctccaggacttctctgcgggtggccca
gaccgcttctacttcctcgaggcctataatgccaagaacaaaagctttgaagatcctcct
aaccatgcccgtagccctggaaataaagggaaggggaaggggaaagggaagggcaaggca
aagtctcaaacgtgcgagccaagtgaaccagagaccgaaattcagctgcccaaactgcgg
accctggacgtgttttctggctgtggagggttgtcggaaggattccaccaagcaggcatc
tcggaaacactgtgggccattgagatgtgggaccctgcggcccaggcgttccggctgaac
aatcccgggtccacggtgttcacggaggactgcaacgtgctgctgaagctggtcatggcc
ggggaggccaccaactcccgcggtcagaagctgcctcagaagggagatgtggagatgctg
tgcggtgggccgccttgccaagggtttagcggcatgaaccgcttcaactctcgcacctac
tccaagttcaagaactccttggtggtttcctttctcagctactgtgactactaccggccc
cgctacttcctcttggagaacgtccggaattttgtttccttcaaacgctccatggtcctg
aagctcactctccgctgccttgtccgtatgggctatcagtgcaccttcggcgtgttgcag
gctggtcagtatggcgtggcccagacccggaggcgggccatcatcctggctgcagccccc
ggagagaagcttcccctgttcccagagccactgcacgtgttcgcaccccgggcctgccag
ctgagcgtcgtggtggacgacaagaagtttgtcagcaacataaccaggttgagctcgggc
ccgttccgaaccatcaccgtgcgggacacgatgtccgacctccccgaggtccggaacgga
gcttcggcgctggagatcttgtacaacggggagcctcagtcctggttccagaggcagctc
cggggctcacagtaccagcccatcctcagggatcacatctgtaaggacatgagcgcgctg
gtggccgcccgcatgcggcacatccctctggccccgggctcagactggcgtgacctgccg
aacatcgaggtgcggctgtccgatggcaccatggccaggaagctgcgatacacgtaccac
gacaagaagaacggctgcagcagcaccggggccctccgcggggtctgctcctgtgtggaa
gcgggcaaagcctgtgactccgcggctagacagttcaacaccctcatcccctggtgcctg
ccccacaccgggaacaggcacaaccactgggccggcctctacggacggctcgagtgggat
ggcttcttcagcacgaccgtcaccaaccccgagcccatgggcaagcagggccgcgttctc
caccctgagcagcaccgcgtcgtgagcgtgcgggagtgcgcccgctcccagggcttcccg
gacacctaccggctgttcggcaacatcctggacaagcaccggcaggtggggaacgctgtg
ccgccgcctctggccaaagccattggcttggagatcaagcgctgtatgttggccaaagct
cgagagagtgcctcagtgaaaatcaaggaggaggaagctaccaaggactag
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integrated database retrieval system
