Panthera leo (lion): 122213954
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Entry
122213954 CDS
T10741
Name
(RefSeq) LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4A-like
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
plez Panthera leo (lion)
Pathway
plez00230
Purine metabolism
plez01100
Metabolic pathways
plez04024
cAMP signaling pathway
plez04928
Parathyroid hormone synthesis, secretion and action
plez05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122213954
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
122213954
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
122213954
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122213954
Enzymes [BR:
plez01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
122213954
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Gene cluster
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Motif
Pfam:
PDEase_I
PDE4_UCR
Emfourin
Motif
Other DBs
NCBI-GeneID:
122213954
NCBI-ProteinID:
XP_042784333
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Position
A2:7832900..7866711
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AA seq
871 aa
AA seq
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MEPPAAPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAVDTGDRPGLRTSRMSWPSSFHGTGTGSGGASGGSCKRFEAENGPTPSPGR
SPLDSQASPGLVLHAGGAISQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPIPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKDREKQPAPRQRPSQQPPPPGPQFQPMSQITGXKKLMHSSSLSDSSIPRFGVKTN
QEELLAQELENLNKWGLNIFCVSEYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYML
TLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEEPRGPGHPPPPDKFQFELTLEEEDEEE
VSTAPGAFTVQGLSVAQDASPAEELLEVDGQDMPTEVKVQEPCCTQQADSAGSVAAGKDK
ATSPDASVDAVGRSSPLALSAESPLPPALRTPPPPEDTPGLPGLPSTAAEAGAQKEHQAA
KRACSACTGTSGEDPPPLPAPGGWGSAGGPT
NT seq
2616 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccggccgccccttcggagaggagcctgtctctgtctctgcccgggccccgg
gagggccaggccaccctgaagccgcccccacagcacctgtggcggcagccgcggacccct
atccgtatccagcagcgcggctactctgacagcgcggagcgcgcagagcccgagcggccg
ccacaccggcccatagagcgcgccgacgccgtggacaccggcgaccggcccggcctgcgc
acttctcgcatgtcctggccctcgtccttccacggtaccggcaccggcagcggcggcgcg
agcggaggcagctgcaagcgcttcgaggcagagaatgggcccacgccatctcctggccgc
agccccctggactcgcaggcgagcccgggcctcgtgctgcacgccgggggggctatcagc
cagcgccgggagtccttcctgtaccgctcggacagtgactatgacatgtcacccaaaacc
atgtcccggaactcgtcggtcaccagcgaggcgcacgctgaggacctcattgtgacacct
ttcgcccaggtgctggccagtctccggagtgttcgcagcaacttctcactcctgaccaat
gtgcccattcccagcaacaaacggtccccgctgggcggcccaacccccgtctgtaaggcc
acgctgtcagaagagacatgtcaacagttggcccgggagacactggaggagctggactgg
tgcctggagcagctggagaccatgcagacctaccgctccgtgagcgagatggcatctcac
aagttcaagaggatgttaaaccgtgaactcacacacctgtcagagatgagcaggtcagga
aaccaggtctctgagtacatctccaccacattcctggacaagcagaatgaagtggagatt
ccatcacccacgatgaaggatcgagaaaaacagccagctccccgccagagaccttcccag
cagcccccgccccctgggccgcaattccagcccatgtctcagatcacggggntgaagaag
ctgatgcatagcagcagcctgagtgactccagcatcccccgctttggggtgaagaccaac
caagaagagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttc
tgcgtatccgaatacgccggaggccgttccctcagctgcatcatgtacacgatatttcag
gagcgtgacctgctgaagaaattccgcatcccagtggacaccatggtgacatatatgctg
accctggaggaccactaccaccccgacgtggcctaccacaacagcctgcacgcggccgat
gtgctgcagtccacccacgtgctgctggccacgcccgcgctagatgctgtgttcacggac
ctggagattcttgccgccctcttcgcggccgctattcatgacgtagaccaccctggggtc
tccaaccagttcctcatcaacactaattcggagttggcgctcatgtacaacgatgagtcg
gtgctggagaaccaccacctggccgtgggcttcaagctgctgcaggaagacaactgcgat
atcttccagaacctcagcaagcgccagcggcagagcctgcgcaagatggtcatcgacatg
gtgctggccacggacatgtccaaacacatgaccctcctggcagacctgaagaccatggtg
gagaccaagaaggtgaccagctcgggggtcctcctgctggacaactactccgaccgcatc
caggtccttcggaacatggtgcactgtgcagacctcagcaaccccaccaagccactcgag
ttgtaccgccagtggaccgaccgcattatggccgagttcttccagcagggggaccgtgaa
cgtgagcggggcatggagatcagccccatgtgcgacaagcacacagcctcggtggagaag
tctcaggtgggtttcatcgactatatcgtgcacccgctgtgggagacgtgggctgacctg
gtccacccggacgcccaggagatcctggacacgttagaggacaacagagactggtactac
agcgccattcggcagagcccatcaccgccgcctgaggaggagcccagggggccaggccac
ccacccccacctgataagttccagttcgagctgacgctggaagaggaagatgaggaggag
gtgtctaccgccccgggtgcatttacggtgcagggattgtccgtggctcaggatgcgtcc
ccagctgaggaactcttggaggtcgatggccaggatatgcccacggaggtgaaggtacag
gaaccttgctgcacgcagcaagcagactcggccggtagtgtggctgcgggcaaggacaag
gccacgtccccagacgcatctgtggatgccgtaggccgcagcagccccctggccttgtct
gccgagagcccccttccgcccgccttgaggaccccgccccctccagaggacaccccgggc
ctcccgggcctcccctccacggcggccgaggcgggggcccaaaaagagcatcaggctgcc
aagagggcgtgcagtgcctgcacaggaacgtccggcgaggacccccccccactcccagct
cctggggggtgggggtcagctggaggccctacctga
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