Panthera leo (lion): 122214206
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Entry
122214206 CDS
T10741
Symbol
UPF1
Name
(RefSeq) regulator of nonsense transcripts 1 isoform X1
KO
K14326
regulator of nonsense transcripts 1 [EC:
5.6.2.5
5.6.2.3
]
Organism
plez Panthera leo (lion)
Pathway
plez03013
Nucleocytoplasmic transport
plez03015
mRNA surveillance pathway
Brite
Enzymes [BR:
plez01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
122214206 (UPF1)
5.6.2.5 RNA 5'-3' helicase
122214206 (UPF1)
Messenger RNA biogenesis [BR:
plez03019
]
Eukaryotic type
mRNA surveillance and transport factors
Surveillance factors
Surveillance complex
122214206 (UPF1)
mRNA cycle factors
Common to processing body (P body) and stress granule
122214206 (UPF1)
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Gene cluster
GFIT
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NCBI-GeneID:
122214206
NCBI-ProteinID:
XP_042784897
UniProt:
A0A8C8WA90
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Position
A2:13879440..13916787
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AA seq
1130 aa
AA seq
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MSVEAYGPSSQTLTFLDTEEAELLGADTQGSEFEFTDFTLPSQTQTPPGGPGGPGGGGAG
GPVGAGAGAAAGQLDAQVGGPEGILQNGAVDDNVAKTSQLLAELNFEEDEEDTYYTKDLP
VHACSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGET
VLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFL
SWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEEPQHVLLRYEDA
YQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSGNEDLVI
IWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDNYGDEIAIELRSSVGAPVEVTHN
FQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQGL
PDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVD
QLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELS
SADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMV
PVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPAL
SAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRT
EAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDA
FQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHL
LNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYD
RSSQGRPSNMYFQTHDQIGMISAGPSHVAAMNIPIPFNLVMPPMPPPGYFGQANGPAAGR
GTPKGKTGRGGRQKNRFGLPGPSQTNLPNSQASQDVASQPFSQGALTQGYISMSQPSQMS
QPGLSQPELSQDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtggaggcgtacgggcccagttcgcagacgctcaccttcctggacactgaggaa
gccgagctgcttggcgccgacacgcagggctcggagttcgagttcaccgacttcaccctc
cccagccagacgcagacgcccccaggtggccccggcggccccggaggaggtggtgcggga
ggcccggtcggcgctggcgcgggcgctgcggccggacagctggacgcgcaggtcggtgga
ccagagggcattctgcagaacggggctgtggatgacaatgtggccaagaccagccagctg
ttggccgagttgaactttgaagaagatgaagaagatacctattacacgaaggatctccct
gtacatgcctgcagttactgcggaatacacgatcctgcttgcgtggtttactgtaatacc
agcaagaagtggttctgtaatggacgtggaaatacttctggcagccacattgtaaatcac
ctcgtgagggcaaaatgcaaagaggtgactctgcacaaggatgggcccctgggggagaca
gttctggagtgttacaactgtggctgccgcaatgtcttcctcctcggcttcatccctgcc
aaagcggactccgtagtggtgctcctgtgcaggcagccctgcgccagtcagagcagcctc
aaggacatcaactgggacagctcccagtggcagcccctgatccaggaccgctgcttcctc
tcttggctggtcaagatcccttctgagcaggagcagctgcgggcccggcagatcactgct
cagcagatcaacaagctggaggagctctggaaggaaaatccttctgccaccttggaggat
ctggagaagcccggtgtggatgaggagccgcagcacgtcctcttgcggtacgaggacgcc
taccagtaccagaacatattcggccctctggtcaagctggaggccgactacgataagaaa
ctgaaagagtcccagactcaagataacatcacggtcaggtgggacctgggccttaacaag
aagagaatcgcctacttcactttgcccaagactgactctggtaatgaggatttagtcata
atttggttaagagacatgcggctcatgcagggagatgagatatgcctgagatacaaaggg
gatctggcacccctgtggaaagggatcggccacgtcatcaaggtccctgataattatggc
gatgagatcgccattgagcttcggagcagtgtgggcgcccctgtggaggtgactcacaac
ttccaggtggatttcgtgtggaagtcaacctcattcgataggatgcagagtgctttgaaa
acgtttgctgtggatgagacctccgtgtcaggctacatctaccacaaactgctcggccac
gaggtggaggatgtgatcatcaagtgccagctgccgaaacgcttcacggcacaggggctc
ccagacctcaaccactcccaggtttacgctgtgaagactgtgctgcagagaccactgagc
ctgattcaggggccaccgggcacggggaagaccgtgacctctgccaccatcgtctaccac
ctggctcggcagggcaacgggcctgtgctcgtctgtgctccgagtaacatagctgtggat
cagctgactgagaagatccaccagactgggctgaaagtcgtgcggctctgcgcgaagagc
cgtgaggccattgattccccggtgtcattcctggccctgcacaaccagatcaggaacatg
gatagcatgccggagctacagaagctgcagcagctgaaggacgagactggggagctgtcc
tctgccgacgagaagcggtaccgggccctgaagcgcaccgccgagcgggagctgctcatg
aatgcagatgtcatctgctgcacgtgtgtgggtgcaggggacccaaggctcgccaagatg
cagttccgctccatcttaattgacgagagcacccaggccaccgaaccagagtgcatggtc
cctgtggttcttggcgccaagcagctcatcctcgtgggcgaccactgccagctgggccct
gtggtgatgtgcaagaaggccgccaaggctggactgtcccagtcgctcttcgagcgcctg
gtagtgctgggcatccgtcccatccgcctccaggtccagtatcggatgcacccagcgctc
agtgccttcccgtccaacatcttctacgagggctctcttcagaacggcgtcaccgcagcg
gatcgagtgaagaaggggtttgacttccagtggccccaacctgataagccaatgttcttc
tacgtgacccagggccaagaggagatcgccagctcaggcacctcctaccttaacaggacg
gaagctgcaaatgtggagaagatcaccacgaagctgctaaaggcgggtgccaagcctgac
cagatcggcatcatcacaccctatgagggccagcgctcctacctggtgcagtacatgcag
ttcagcggctccttgcacaccaagctctaccaggaggtggagattgccagtgtggacgcg
ttccagggacgagagaaggacttcatcatcctttcctgtgtgcgagccaacgagcaccaa
ggcattgggtttttaaacgaccccaggcggcttaatgtggctctgaccagagcacggtat
ggggtcattatcgtgggcaacccaaaggccttgtccaagcagccgctctggaaccacctg
ctgaactactacaaggagcagaaggtgctggtggaggggcccctgaacaaccttcgggag
agcctcatgcagttcagcaagcccaggaagctggtcaacaccatcaacccgggagcccgc
ttcatgacaacagccatgtatgatgctcgggaggccattatcccaggatcagtctatgat
cggagcagccagggccggccctcaaacatgtacttccagacccacgaccagatcggcatg
atcagtgcgggacccagccacgtggctgccatgaacattcccatccctttcaacctggtc
atgccacccatgccaccaccagggtattttggacaagccaacgggccagccgcaggccgg
ggtaccccaaaaggcaagactggtcgtggggggcgccagaagaaccgctttgggctccct
ggacccagccagacgaatctccccaacagccaggccagccaggatgtggcatcacagccc
ttctcccagggcgccctgacacagggctacatctccatgagccagccctcccagatgagc
cagcccggcctctcccagcccgagctgtcccaggacagttaccttggcgatgagtttaag
tcacagattgatgtggcgctgtcgcaagactccacgtaccaaggggagcgggcgtaccag
cacggcggagtgacagggctgtcccagtactag
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