Panthera leo (lion): 122214502
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Entry
122214502 CDS
T10741
Symbol
PDHB
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit beta, mitochondrial
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
plez Panthera leo (lion)
Pathway
plez00010
Glycolysis / Gluconeogenesis
plez00020
Citrate cycle (TCA cycle)
plez00620
Pyruvate metabolism
plez00785
Lipoic acid metabolism
plez01100
Metabolic pathways
plez01200
Carbon metabolism
plez01210
2-Oxocarboxylic acid metabolism
plez04066
HIF-1 signaling pathway
plez04922
Glucagon signaling pathway
plez05230
Central carbon metabolism in cancer
plez05415
Diabetic cardiomyopathy
Module
plez_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
Enzymes [BR:
plez01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
122214502 (PDHB)
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NCBI-GeneID:
122214502
NCBI-ProteinID:
XP_042785744
UniProt:
A0A8C8X2I1
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Position
A2:complement(26133677..26139686)
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AA seq
359 aa
AA seq
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MAAVSGLVRRPLEQVSGLLRRRFHRTAPAALQVTVREAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGFQSVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPSEAQSKDFLIPIGKAKIERQGTHITVV
SHSRPVGHCLEAATVLSKEGIECEVINMRTIRPMDIETIEASVMKTNHLITVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggctgtgtctgggctggtgcggagaccccttgaacaggtctccgggctgctgagg
aggcgcttccaccgaacggcgccggcggcgctgcaggtgacagttcgtgaagctataaac
caaggtatggatgaggagctggaaagagatgagaaggtgtttctgcttggggaagaagtt
gcccagtatgatggggcatataaggttagtcgaggcctgtggaagaaatacggagataag
aggatcatagacactcccatatctgagatgggctttgctggaattgccgtgggtgcggcc
atggctgggttgaggcccatttgtgaatttatgaccttcaatttctcaatgcaagccatt
gaccaggttataaactcagctgccaagacctactacatgtcagggggctttcagtctgtg
cccatagtcttcagggggcccaatggcgcctcagcaggcgtggctgcccagcactcacag
tgctttgctgcctggtatgggcactgcccaggcttaaaggtggtcagcccctggaattca
gaggatgcaaaaggacttattaaatcagccattcgggataacaacccagtggtggtgcta
gagaacgaactgatgtatggagttccttttgaatttccctcagaagctcaatcaaaagat
tttctgattcccattggaaaggccaaaatagaaaggcaagggacacacataactgtagtt
tcccattcaagacccgtgggccactgcttagaagctgcaacggtgctatccaaagaagga
attgaatgtgaggtgataaatatgcgaaccatcagaccaatggacattgaaacaatagaa
gccagtgtcatgaagaccaatcatctgataactgtggaaggaggctggccacagtttgga
gtaggagctgaaatttgtgccaggatcatggaaggccctgcattcaatttcctggatgct
cctgcagttcgcgtcactggtgctgatgtccctatgccttatgcaaagattctagaagac
aactcggtacctcaggttaaagacatcatatttgcaataaagaaaacattaaatatctag
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