Panthera leo (lion): 122214861
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Entry
122214861 CDS
T10741
Symbol
PCK1
Name
(RefSeq) phosphoenolpyruvate carboxykinase, cytosolic [GTP]
KO
K01596
phosphoenolpyruvate carboxykinase (GTP) [EC:
4.1.1.32
]
Organism
plez Panthera leo (lion)
Pathway
plez00010
Glycolysis / Gluconeogenesis
plez00020
Citrate cycle (TCA cycle)
plez00620
Pyruvate metabolism
plez01100
Metabolic pathways
plez03320
PPAR signaling pathway
plez04068
FoxO signaling pathway
plez04151
PI3K-Akt signaling pathway
plez04152
AMPK signaling pathway
plez04910
Insulin signaling pathway
plez04920
Adipocytokine signaling pathway
plez04922
Glucagon signaling pathway
plez04931
Insulin resistance
plez04964
Proximal tubule bicarbonate reclamation
Module
plez_M00003
Gluconeogenesis, oxaloacetate => fructose-6P
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
122214861 (PCK1)
00020 Citrate cycle (TCA cycle)
122214861 (PCK1)
00620 Pyruvate metabolism
122214861 (PCK1)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
122214861 (PCK1)
04151 PI3K-Akt signaling pathway
122214861 (PCK1)
04152 AMPK signaling pathway
122214861 (PCK1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
122214861 (PCK1)
04922 Glucagon signaling pathway
122214861 (PCK1)
04920 Adipocytokine signaling pathway
122214861 (PCK1)
03320 PPAR signaling pathway
122214861 (PCK1)
09155 Excretory system
04964 Proximal tubule bicarbonate reclamation
122214861 (PCK1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04931 Insulin resistance
122214861 (PCK1)
Enzymes [BR:
plez01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.32 phosphoenolpyruvate carboxykinase (GTP)
122214861 (PCK1)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PEPCK_GTP
PEPCK_N
Motif
Other DBs
NCBI-GeneID:
122214861
NCBI-ProteinID:
XP_042786037
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All DBs
Position
A3:complement(5577311..5582797)
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AA seq
622 aa
AA seq
DB search
MPPQLPSSLNFSAKVVQGTLDSLPQAVRAFVESSAKLCQPDHIHICDGSDGENRKLLDHM
EAQGVIKRLRKYHNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKTGPSQLGRWMSEE
DFEKAFNARFPGCMKGRTMYIIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPV
LEALGDGDFVKCLHSVGCPLPLKKPLVNNWPCNPEMTLIAHLPDRREIISFGSGYGGNSL
LGKKCFALRIASRLAKEEGWLAEHMLILGITNPKGQKKYFAAAFPSACGKTNLAMMNPSL
PGWKIECVGDDIAWMKFDQEGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNV
GETSDGGFYWEGIDQPLAPGIRLTSWKNKEWSPQDGEPCAHPNSRFCTPASQCPIIDPAW
ESPEGVPIEGIIFGGRRPAGVPLVYEALTWQHGVFVGAAMRSEATAAAEHKGKVIMHDPF
AMRPFFGYNFGKYLAHWLSMAQRPAAKLPKIFHVNWFRKDDEGKFLWPGFGENSRVLEWM
FNRINGEAGAKLTPIGYIPEEGALNLKGLGDVNVKELFDIPKGFWEKEVMDLQKYLEDQV
NTDLPYEIEREVLALKQRISQM
NT seq
1869 nt
NT seq
+upstream
nt +downstream
nt
atgcctcctcagctccccagcagcctcaatttctcggccaaggtcgtccagggcacccta
gacagcctgccccaggcggtgagagcattcgtggagagtagcgccaagctgtgccagccc
gaccatatccacatctgtgatggctccgacggcgagaaccggaagctgctggaccacatg
gaggcccagggggtgatcaagaggctgcggaaataccacaactgctggctggctctcact
gaccccagggatgtggccagaattgaaagcaagacggtcatcattacccaagagcaaaga
gataccgtgcccatccccaaaaccggccctagccaactaggtcgctggatgtccgaggag
gacttcgagaaagcattcaatgcccgattcccagggtgcatgaaaggtcgtaccatgtac
atcatcccattcagcatggggccgctgggctcccctctgtcgaagatcggcatcgagctg
acagactccccctacgtggtggccagcatgcgcatcatgacgaggatgggcaccccggtc
ctggaagcgctgggtgacggggacttcgtcaagtgcctccattccgtgggatgccctctg
cctttaaaaaagcccctggtgaacaactggccttgcaacccagagatgaccctcatcgcc
cacctgcccgaccgcagggaaatcatctccttcgggagtgggtacggcgggaactcgctc
ctcgggaagaagtgcttcgccctcaggatagccagccggctggctaaggaagaggggtgg
ctggcagaacacatgctgatcctgggcatcaccaaccccaagggccagaagaagtatttc
gcagcagcctttcccagtgcctgtgggaagaccaacctggccatgatgaaccccagcctc
ccagggtggaagatagagtgtgtgggagatgacattgcctggatgaaatttgaccaagaa
ggtaacctaagggctatcaacccagaaaatggctttttcggggtggctcctggaacctct
gtgaagaccaaccccaacgccatcaagaccatccagaagaacaccatcttcactaacgtg
ggcgagaccagcgacgggggcttttattgggaaggtatcgaccagccgctggccccgggc
atcaggctcacctcgtggaagaacaaggaatggtccccccaggacggggaaccttgcgcc
catcccaactcacgcttctgcacccctgccagccagtgtcccatcatcgaccctgcctgg
gagtctccggaaggggtgcccatcgagggcatcatcttcggaggccgccgacctgccggg
gtccctctggtctacgaagctctcacctggcagcatggagtgtttgtgggggcggcgatg
cgatcagaggccacagcagccgcggaacacaaaggcaaggtcatcatgcacgaccccttt
gccatgcggcctttctttggctacaactttggcaaatacctggcccactggctcagcatg
gcccagcgcccagcagccaagctgcccaagatcttccacgtcaactggttccggaaagac
gacgaaggcaaatttctctggccgggctttggggagaactccagggtgctggaatggatg
ttcaaccggatcaacggggaagcgggtgccaagctcacgcccataggctacatccctgag
gagggcgccctgaacctgaaaggcctgggggacgtcaacgtgaaggagctcttcgacatc
cccaaggggttctgggagaaggaggtgatggacctccagaagtacttggaggaccaagtt
aacaccgacctgccctacgagatcgagagagaggtccttgccctgaagcaaaggatcagc
cagatgtaa
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