Panthera leo (lion): 122215406
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Entry
122215406 CDS
T10741
Symbol
NFATC2
Name
(RefSeq) nuclear factor of activated T-cells, cytoplasmic 2 isoform X1
KO
K17332
nuclear factor of activated T-cells, cytoplasmic 2
Organism
plez Panthera leo (lion)
Pathway
plez04020
Calcium signaling pathway
plez04022
cGMP-PKG signaling pathway
plez04148
Efferocytosis
plez04218
Cellular senescence
plez04310
Wnt signaling pathway
plez04360
Axon guidance
plez04370
VEGF signaling pathway
plez04380
Osteoclast differentiation
plez04625
C-type lectin receptor signaling pathway
plez04650
Natural killer cell mediated cytotoxicity
plez04658
Th1 and Th2 cell differentiation
plez04659
Th17 cell differentiation
plez04660
T cell receptor signaling pathway
plez04662
B cell receptor signaling pathway
plez04921
Oxytocin signaling pathway
plez05135
Yersinia infection
plez05161
Hepatitis B
plez05163
Human cytomegalovirus infection
plez05166
Human T-cell leukemia virus 1 infection
plez05167
Kaposi sarcoma-associated herpesvirus infection
plez05170
Human immunodeficiency virus 1 infection
plez05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
plez05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
122215406 (NFATC2)
04370 VEGF signaling pathway
122215406 (NFATC2)
04020 Calcium signaling pathway
122215406 (NFATC2)
04022 cGMP-PKG signaling pathway
122215406 (NFATC2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
122215406 (NFATC2)
09143 Cell growth and death
04218 Cellular senescence
122215406 (NFATC2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
122215406 (NFATC2)
04650 Natural killer cell mediated cytotoxicity
122215406 (NFATC2)
04660 T cell receptor signaling pathway
122215406 (NFATC2)
04658 Th1 and Th2 cell differentiation
122215406 (NFATC2)
04659 Th17 cell differentiation
122215406 (NFATC2)
04662 B cell receptor signaling pathway
122215406 (NFATC2)
09152 Endocrine system
04921 Oxytocin signaling pathway
122215406 (NFATC2)
09158 Development and regeneration
04360 Axon guidance
122215406 (NFATC2)
04380 Osteoclast differentiation
122215406 (NFATC2)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
122215406 (NFATC2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
122215406 (NFATC2)
05170 Human immunodeficiency virus 1 infection
122215406 (NFATC2)
05161 Hepatitis B
122215406 (NFATC2)
05163 Human cytomegalovirus infection
122215406 (NFATC2)
05167 Kaposi sarcoma-associated herpesvirus infection
122215406 (NFATC2)
09171 Infectious disease: bacterial
05135 Yersinia infection
122215406 (NFATC2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122215406 (NFATC2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
plez03000
]
122215406 (NFATC2)
Transcription factors [BR:
plez03000
]
Eukaryotic type
beta-Scaffold factors with minor groove contacts
RHR (Rel homology region) NF-AT
122215406 (NFATC2)
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Paralog
GFIT
Motif
Pfam:
RHD_dimer
RHD_DNA_bind
TIG
Motif
Other DBs
NCBI-GeneID:
122215406
NCBI-ProteinID:
XP_042786588
LinkDB
All DBs
Position
A3:10489164..10648629
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AA seq
922 aa
AA seq
DB search
MDAPEPQPDPDGGDAPGHEPGGSPQDEFDFSILFDYDYLNPIEEEPNAHKVASPPSGLAY
PDDVLDYGLKPYSPLPSLPGEPPGRFGEPDRVGPQNFLSAAQPAGASGLSPRIEITPSHE
LMQAGGPLRGRDAGLLGEQPALAGAAASPRFTLPVPGFEGYREPLCLSPASSGSSASFVS
DTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTGLAEDSCLGRRSPAPR
PASRSSSPGAKRRHSCAGAPVAPLPGASPQRSRSPSPQPRDDGAPAGYPAAAGSAVLMDA
LNSLAADSPCGIPPKMWKTSPEPAPVSAAPPKAGLPRHLYPAAVEFLGPCEQEERRNSAP
ESILLMPPTWPKQLVPALPLCSIPVTASLPPLEWPLSHQSGSYELRIEVQPKPHHRAHYE
TEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVT
TTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLV
FRVHIPEASGRIISLQTASNPIECSQRSAHELPMVERQDIDSCLVYGGQQMILTGQNFTA
ESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRASVKVNFYVINGKR
KRSQPQHFTYHPVPAIKTEPTDEYDPTLICSPAHGGLGSQPYYPQHPMVAESPSCLVATM
APCQQFRSGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADAHRSVL
VHAGSQGQSSSLLHSSPANQQASPVIHYSPTGQQLRCGGHQEFQHIMYCENFAPGTARPG
PPPASQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNLDQTYL
DDGKGVFKQQPRERDPRVWLMG
NT seq
2769 nt
NT seq
+upstream
nt +downstream
nt
atggacgccccggagccgcagcccgaccccgacggcggggacgccccaggccacgagccc
gggggcagcccccaagacgagttcgacttctccatcctcttcgactatgactatttgaat
cctatcgaagaagaaccgaatgcacataaggtcgccagcccaccctccggactcgcatac
cccgatgatgtcctggactatggcctcaagccatacagccccctccccagtctcccgggc
gagccccccggccgattcggagagccggatagggtagggccgcagaactttctgagcgcg
gcccagccagccggggcctcgggcctgagccctcggatcgagatcactccatctcacgaa
ctgatgcaggcagggggccccctccgcgggagagacgctggcctgctgggggagcagccg
gccctggccggggcggccgccagcccgcggttcacgctgcccgtgcccggcttcgagggc
taccgcgagccgctttgcttgagcccggctagcagcggctcctctgccagcttcgtttcc
gacaccttctccccctacacctcgccctgcgtctcgcccaataacggcgggcccgacgac
ctgtgcccccagtttcaaaacatccctgctcattattcccccagaacctcgccaataatg
tcacctcgaaccggcctcgctgaggacagctgcctgggccgccgctcgcccgcgccccgt
ccggcctcccgctcctcgtcgcctggcgccaagcggaggcattcgtgcgccggggccccg
gtcgccccgctgcccggagcctcgccccagcgctcccggagcccctcgccgcagccccgg
gacgacggcgcccccgccggctaccccgccgcggccggctccgccgtcctcatggacgcc
ctgaacagcctcgccgccgactcgccctgcggcatcccgcccaagatgtggaagaccagc
cccgagccggcgcccgtgtccgccgccccgcccaaggccggcctgccccgccacctgtac
ccggccgccgtggaatttctgggcccctgcgagcaggaggagaggaggaactcggccccc
gagtccatcctgctgatgccgcccacgtggcccaagcagctggtgcccgcccttcccctc
tgcagtattccagtgaccgcatccctccctccgcttgagtggccactctcccaccagtcg
gggtcctatgagctgcggattgaggtgcagcccaagccacatcaccgggcccactatgag
acagaaggcagccgaggggctgtcaaagctccaactggtggccaccctgtcgttcagctc
catggctacatggaaaacaagcccctcgggcttcagatcttcattgggacagccgacgag
cgcatccttaagccccacgccttctaccaggtgcaccgcatcacgggaaaaaccgtcacc
accaccagctacgagaagatcgtaggcaacaccaaagtcctggagatccctctggagcca
aagaacaacatgagggcgaccattgactgtgcggggatcctgaagctgaggaacgcggac
atcgagctgcggaaaggcgagacggacatcggcaggaagaacacgcgggtgcggctggtt
ttccgggtgcacattccagaggccagcgggaggatcatctccctgcagactgcatccaac
cccatcgaatgctcccagcgatccgcccacgagctgcccatggtggaaagacaggacatc
gacagctgcctggtctacgggggccaacagatgatcctcacgggacagaacttcacagcc
gagtccaaagtcgtgtttactgagaagaccacagatgggcagcaaatttgggaaatggaa
gccacggtggataaagacaagagccagcctaacatgctttttgttgagatccctgaatat
cgaaacaagcacatccgtgcatcggtgaaggtcaacttctacgtcatcaatgggaaaaga
aaacggagtcaacctcagcactttacttaccacccagtcccagccatcaagacggaaccc
accgacgaatacgaccccaccttgatctgcagcccggcccacgggggcctggggagccag
ccttactacccacagcacccgatggtggctgagtccccctcctgcctcgtggccaccatg
gcgccctgccaacagttccgctcggggctctcgtcccccgacgcccgctaccagcagcag
aacccagcggccgtcctctaccagcggagcaagagcctgagccccagcctgctgggctac
cagcagccggccctcatggccgcccccctgtcgctggcggacgcccaccgctccgtgctg
gtgcacgccggctcccagggccagagctccagcctgctgcactcctctccggccaaccag
caggcctcgccggtgatccactactcgcccaccggccagcagctgcgctgcggtggccac
caggaattccagcacatcatgtactgcgagaatttcgcgcccggcaccgccaggcccggc
ccaccccccgccagtcaaggtcagaggctgagcccggggtcctaccccacggtcattcag
cagcagaatgccaccagccaaagagccgccaaaaacggacccccggtcagtgaccaaaag
gaagtattacccgcaggagtgacaattaagcaggagcagaatttggaccagacctacttg
gacgacggaaaaggagttttcaaacagcaaccaagggaacgtgacccaagagtctggctt
atgggctga
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