Panthera leo (lion): 122215740
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Entry
122215740 CDS
T10741
Symbol
NLRP3
Name
(RefSeq) NACHT, LRR and PYD domains-containing protein 3 isoform X1
KO
K12800
NACHT, LRR and PYD domains-containing protein 3
Organism
plez Panthera leo (lion)
Pathway
plez04217
Necroptosis
plez04621
NOD-like receptor signaling pathway
plez04623
Cytosolic DNA-sensing pathway
plez04625
C-type lectin receptor signaling pathway
plez05132
Salmonella infection
plez05133
Pertussis
plez05135
Yersinia infection
plez05164
Influenza A
plez05171
Coronavirus disease - COVID-19
plez05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
122215740 (NLRP3)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
122215740 (NLRP3)
04623 Cytosolic DNA-sensing pathway
122215740 (NLRP3)
04625 C-type lectin receptor signaling pathway
122215740 (NLRP3)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
122215740 (NLRP3)
05164 Influenza A
122215740 (NLRP3)
09171 Infectious disease: bacterial
05132 Salmonella infection
122215740 (NLRP3)
05135 Yersinia infection
122215740 (NLRP3)
05133 Pertussis
122215740 (NLRP3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122215740 (NLRP3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
plez04131
]
122215740 (NLRP3)
09183 Protein families: signaling and cellular processes
04054 Pattern recognition receptors [BR:
plez04054
]
122215740 (NLRP3)
Membrane trafficking [BR:
plez04131
]
Autophagy
Other autophagy associated proteins
TRIM-directed selective autophagy
122215740 (NLRP3)
Pattern recognition receptors [BR:
plez04054
]
Cytoplasmic pattern recognition receptors
NOD-like receptors
122215740 (NLRP3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NACHT
NLRC4_HD2
PYRIN
FISNA
LRR_6
NOD2_WH
LRR_4
nSTAND3
NB-ARC
Motif
Other DBs
NCBI-GeneID:
122215740
NCBI-ProteinID:
XP_042787368
UniProt:
A0A8C8W9E7
LinkDB
All DBs
Position
A1:complement(87532853..87592938)
Genome browser
AA seq
1032 aa
AA seq
DB search
MNMASVRCKLARYLEDLGDTDFKKFKMHLEDYPSQKGFSPLPRSQTEKADHMDLATLMID
FNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPQWDNAHVVYREESLEEEWMGLFGYLSRI
SICKKKKDYCKKYKKHVRSRFQCIKDRNARLGESVNLNKRYTRLRLVKEHKNQQEREHEL
LAIGRTSAKMLDSPVSSLNVELLFEPDDQHSEPVHTVVFQGAAGIGKTILARKIMLDWAS
EKIYQDRFDYLFYIHCREVSLGTRRSLGDLIVSCCPDPNPPICKIVSKPSRILFLMDGFD
ELQGAFDEHTEALCTNWQKVERGDILLSSLIRKRLLPEASLLITTRPVALEKLQHLLDRP
RHVEILGFSEAKRKEYFFKYFSDEQQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQ
MDSGKSLAQTSKTTTAVYIFFLSTLLQSRRGNQNHDVSTNLRGLCSLAADGIWNQKILFE
ECDLRNHGLQKADVSAFLRINLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEGQGDTG
SLLLSGSKLPNRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQI
RLELLKWIEKKAKAKNLQIQPSQLELFYCLYEMQEEDFVQKAMGHFPQIDINLSTRMDHV
VSSFCIENCQGVESLSLRLLHNSPKEEEEEEEEEVQHCEVDHCVLLDPHAAYTHRLVNCH
LTVSLWQGLFSVLSTSWNLTELNLSDNALGDPGMMVLCEMLQRPGCNVQRLWLGRCCLSY
QCCFNISSVLSSNQKLVELDLSHNSLGDFGIRLLCVGLRHVFCNLKKLWLVSCCLTSACC
EDLASVLSTSQSLTRLYLGENALGDSGVGILCEKAKHPQCKLQKLGLMNSGLTSGCCPAL
SSVLSTNQKLTHLYLRGNALGDTGVKLLCEGLLHPSCKLQILELDNCSLTSHCCWDLSTL
LTSNQSLRDLSLGNNDLGDLGVMLLCEVLRQQGCLLKRLKLCGMYFNYDTKCALEILQEE
KPELTIVFEPSW
NT seq
3099 nt
NT seq
+upstream
nt +downstream
nt
atgaacatggcaagtgtccgctgcaagttggcccgttacctggaggatttgggggacaca
gactttaagaaattcaagatgcacttagaagactacccttctcaaaaggggttcagccca
ctccctcggagtcagacagagaaggcagaccacatggatctagctactttgatgattgac
ttcaatggtgaggagaaagcatgggccatggcagtgtggatttttgctgcaatcaacagg
agagacctttatgaaaaagctaagagggatgagccacagtgggataatgcacatgtggta
taccgggaagaaagccttgaagaagagtggatgggtttattcgggtacctatccagaatc
tctatttgtaaaaaaaagaaggattactgtaagaagtacaaaaaacatgtgaggagcaga
ttccagtgtatcaaagataggaatgctcgtctgggtgagagcgtgaacctcaacaaacgc
tataccaggctgcgtcttgtcaaggaacacaagaaccagcaagagagggaacatgagctc
ctggccattggcaggacttcagccaagatgctggacagccctgtgagctccctgaatgtg
gaattactgtttgagcctgacgaccaacactctgagcctgttcacacggtggtattccag
ggagcagcaggcattgggaaaacaatactggcaaggaagatcatgttggactgggcatca
gagaaaatttaccaggacaggtttgactatttgttttatatccactgtcgggaagtgagt
ctcgggacacggaggagcctgggagacctgattgtcagctgctgcccagatccaaaccca
cccatatgcaagattgtgagcaagccttctcggattctcttcctcatggatggcttcgat
gaacttcagggtgcctttgatgagcacacagaggcgctctgtacaaactggcagaaggta
gagcggggagacattctcctgagcagcctcatcagaaagaggctgcttcccgaggcctct
ttacttatcaccacgagacctgtggctctggagaaactacagcatttgctggaccggccc
cgtcatgtggagatcctgggtttctcagaggccaaaagaaaggaatactttttcaagtat
ttctcagatgagcagcaagccagggaggccttcaggctgattcaggagaatgagatcctc
ttcaccatgtgctttatccccttggtctgctggattgtgtgcactgggttgaagcagcag
atggacagtggcaagagtcttgcccagacatccaagaccaccactgcagtgtacatcttc
ttcctctccactttgttgcaatcccgcagagggaaccagaaccacgatgtctctactaac
ctccggggtctctgttccttggccgcagatggaatctggaaccagaaaatcctgtttgag
gagtgcgaccttaggaatcatggccttcagaaggcagatgtatctgctttcttgaggatc
aacctattccagaaggaagtggactgcgagaaattctacagcttcatccacatgaccttc
caggaattctttgctgccatgtactacttgctggaagaggagggacagggagacacaggg
agcttgctgttgagtggttccaagcttcccaaccgagatgtgacagtccttctggaaaac
tatggcaagtttgaaaaggggtatctgattttcgttgtccgtttcctctttggccttgtc
aaccaggagagaacctcctacttggagaaaaaactgagttgcaagatatctcagcaaatc
aggctggagctgctaaaatggattgaaaagaaagccaaggccaagaatctgcagatccag
cccagccagttggagttgttctactgtctatatgagatgcaagaggaggactttgtgcaa
aaggccatgggccatttcccccaaattgacatcaatctctctaccagaatggaccatgta
gtttcttctttttgtattgagaactgtcaaggtgtggaatcactttccctgaggttgctt
cataactctccaaaggaagaggaggaggaagaggaggaggaagtgcaacactgtgaggtg
gaccactgtgtcctcctagatcctcatgctgcctatactcaccggttggtgaactgccat
ctcactgttagcctttggcagggtctcttctcagtcctaagcactagctggaacctcacg
gaactgaacctcagtgacaatgctctgggggacccagggatgatggtgttatgtgagatg
ctccagcgtcctggctgtaatgttcagagattgtggttggggcggtgttgcctttcctat
cagtgctgcttcaacatctcctcggtcctgagcagcaatcagaagctggtagaattggat
ctgagccacaacagcttgggagattttggaatcagacttctttgtgtgggactgaggcat
gtattctgcaatctgaagaagctctggttggtcagttgctgtctcacatcagcatgttgt
gaggacctggcatccgtcttgagcaccagccagtccctgaccagactctacttgggggaa
aatgcgctgggagactcaggagttggaattctatgtgaaaaagcaaagcatccacaatgt
aagctgcagaaactggggttgatgaattctggacttacatcaggttgctgtccagctctg
tcttcagtgctcagcactaaccagaaactcacacacctttacctaaggggcaatgctctt
ggagacacgggggtgaagctactctgtgagggcctcttgcaccccagctgcaagcttcag
atattggaattggacaactgtagtctcacctcacactgttgctgggacctttccacactt
ctgacctccaaccagagcctgcgggacctgagcctaggcaacaatgaccttggtgatctg
ggggtcatgctactctgtgaggtgctgaggcagcagggctgcctcctgaaacgcctgaag
ttgtgtggaatgtatttcaattatgatacaaaatgtgcattagaaatacttcaagaagaa
aagcctgagttgaccattgtctttgagccttcttggtag
DBGET
integrated database retrieval system
