Panthera leo (lion): 122215838
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Entry
122215838 CDS
T10741
Symbol
PCSK2
Name
(RefSeq) neuroendocrine convertase 2 isoform X1
KO
K01360
proprotein convertase subtilisin/kexin type 2 [EC:
3.4.21.94
]
Organism
plez Panthera leo (lion)
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
plez01002
]
122215838 (PCSK2)
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
plez03110
]
122215838 (PCSK2)
Enzymes [BR:
plez01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.94 proprotein convertase 2
122215838 (PCSK2)
Peptidases and inhibitors [BR:
plez01002
]
Serine peptidases
Family S8: subtilisin family
122215838 (PCSK2)
Chaperones and folding catalysts [BR:
plez03110
]
Intramolecular chaperones
Subtilisin family
122215838 (PCSK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_S8
P_proprotein
S8_pro-domain
Peptidase_S8_N
Motif
Other DBs
NCBI-GeneID:
122215838
NCBI-ProteinID:
XP_042787605
UniProt:
A0A8C8WFX3
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Position
A3:42309281..42581280
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AA seq
638 aa
AA seq
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MKGGCVSQWKAAAGLLFCVMVFASAERPVFTNHFLVELHKGGEEEARQVAAEHGFGVRKL
PFTDGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDIN
MNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASN
YNAEASYDFSGNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRM
LDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGK
GSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRK
RNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDIQHLTVLTSKRN
QLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIP
STGKLVLTLTTDACEGKENFVRYLEHVQAVITVNASRRGDLNINMTSPMGTKSILLSRRP
RDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSTPQKGVLKEWTLMLHGTQSAPYI
DQVVRDYQSKLAMSKKEELEEELDEAVERSLKSILREN
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atgaaaggtggctgtgtctcccagtggaaggcggccgccgggctcctcttctgtgtcatg
gtttttgcatctgccgagagaccggtcttcacgaatcattttcttgtggagttgcataaa
ggaggagaggaagaagctcgccaagttgcagcagaacacggctttggagtccgaaagctc
cccttcactgacggcctataccacttttaccacaatggccttgcaaaggccaagagaaga
cgcagcctacatcacaagcagcagctggagagagaccccagggtaaagatggccttgcag
caggaaggatttgacagaaagaagcgggggtatagagacatcaatgagattgacatcaac
atgaatgatcctctttttacaaagcagtggtatctgatcaacacagggcaagccgatggc
actcctggtcttgatttgaatgtggcagaagcttgggagctgggatacacagggaaaggt
gtcaccattggaattatggatgatgggattgactacctgcacccggacctggcctcgaac
tataacgccgaagcgagctatgacttcagcggcaatgacccctacccctaccctcgatac
acagacgactggttcaacagccatgggacccgatgtgcaggggaggtttctgccgcagcc
aacaacaatatctgtggggtcggagtggcatacaactccaaggttgcaggtatccggatg
ctagaccagccattcatgacagacatcattgaggcctcttccatcagccacatgcctcag
ctgatcgacatctacagtgccagctggggcccgacagacaacgggaagacagtggatgga
ccccgggagctcacgcttcaggccatggccgatggcgtcaacaagggtcgaggcggcaaa
ggcagcatctacgtgtgggcctccggggacggcggcagctacgacgactgtaactgtgat
ggctacgcctccagcatgtggaccatctccatcaactcggccatcaacgacggcagaacc
gccctgtacgacgagagctgctcctccaccttggcctccaccttcagcaacgggaggaag
aggaaccctgaggccggcgtggcaaccacagatttgtatggcaactgcactctgaggcat
tctgggacatccgcggctgcccccgaggcagctggagtgtttgcactggctttagaggct
aacctgggtctgacctggagagacatacagcatctgactgtgcttacctccaaacggaac
cagcttcacgacgaggtccatcaatggcggagaaatggggttggcctggagtttaatcac
ctctttggctacggggtccttgatgcaggcgccatggtgaaaatggctaaagactggaaa
actgtgcccgagagattccactgtgtaggaggctccgtgcaggaccctgagaaaataccc
tccactggcaagttggtgctgaccctcacgaccgacgcatgtgaggggaaagagaacttc
gtccgctaccttgagcacgtccaagctgtcatcacggtcaatgcaagcaggagaggagac
ctgaacatcaacatgacctccccaatgggcaccaagtccatattgctgagccggcgtccg
cgggatgacgactccaaggtgggctttgacaagtggcctttcatgaccacccacacgtgg
ggggaagacgctcgaggaacctggaccctggagctggggtttgtcgggagcaccccccag
aagggggtgctgaaggagtggacactgatgctgcatggcacgcagagcgccccttacatt
gaccaggtagtgagggattaccagtccaagctggccatgtccaagaaggaggagctggag
gaggagctggatgaagccgtggagagaagtctgaagagcatcctgcgcgagaactag
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