Panthera leo (lion): 122216012
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Entry
122216012 CDS
T10741
Symbol
EPAS1
Name
(RefSeq) endothelial PAS domain-containing protein 1
KO
K09095
hypoxia-inducible factor 2 alpha
Organism
plez Panthera leo (lion)
Pathway
plez04066
HIF-1 signaling pathway
plez05200
Pathways in cancer
plez05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
122216012 (EPAS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122216012 (EPAS1)
09162 Cancer: specific types
05211 Renal cell carcinoma
122216012 (EPAS1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
plez03000
]
122216012 (EPAS1)
04131 Membrane trafficking [BR:
plez04131
]
122216012 (EPAS1)
Transcription factors [BR:
plez03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
122216012 (EPAS1)
Membrane trafficking [BR:
plez04131
]
Autophagy
Pexophagy
Other pexophagy associated proteins
122216012 (EPAS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
HIF-1
PAS
PAS_9
PAS_4
HLH
Corona_I
Motif
Other DBs
NCBI-GeneID:
122216012
NCBI-ProteinID:
XP_042788121
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All DBs
Position
A3:65747870..65831926
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AA seq
871 aa
AA seq
DB search
MTTDKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLA
ISFLRTHKLLSSVCSENESEAEANQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMG
LTQVELTGHSIFDFTHPCDHEEIRENLSLKNGSGFGKKGKDMSTERDFFMRMKCTVTNRG
RTVNLKSATWKVLHCTGQVKVYNSCPPHSSLCSFKEPLLSCLIIMCEPIQHPSHMDIPLD
SKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKG
QVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTE
SLFKPHLTAMSSIFDSSSEVAVSEQSDYLFTKLKEEPEELAQLAPTAGDAIIALDFGSQN
FEKSSAYSSALLPPSQPWSRELRSHSTQSEAGSLPAFTVPQAAASGSATPSATSSSSCST
PSSPGDYYTSLNDDLKIEVIEKLFTIDTEAKDQGSTQTDFSELDLETLAPYIPMDGEDFQ
LSPICPEERLLQEKPQSTPQHCFSTMTNIFQPLAPVASHSPFLLDKYQQQLGSKKIEPEH
RPLSSIFFDGGSKVSLPACCGQAGTPLSSLGGRSSSTQWPPDPPLHFGPTKWPVVDQHTE
SLGPSPLGPPVNSPHLSVFKKKSAKGFGPQGPDVMSPAMVALSNKLKLKRQREYEEQAFQ
DLSGIQGDPSGSSTSHQMWKRMKSLRGSVNCPLVPDKLLSASPPSDEFTQLPMRGAGQPL
RHLPPPPSAMSPRENTKSGFPPQCYAPQYQDYSLPSAPKVSGMASRLLGPSFEPYLLPEL
TRYDCEVNVPVPGSSTLLQGGDLLRALDQAT
NT seq
2616 nt
NT seq
+upstream
nt +downstream
nt
atgacaactgacaaggagaagaaaaggagcagctcggagaggaggaaggagaagtcccgg
gatgctgcccggtgccgacggagcaaggagacggaggtcttctacgagctggcccacgag
ctgcccctgcctcacagcgtgagctcccacctggacaaagcctccatcatgcggctggcc
atcagcttcctgcgcacacacaagctcctgtcctcagtttgctctgaaaatgagtctgaa
gctgaggctaaccaacagatggacaacttgtacctgaaagcgttggagggtttcattgcc
gtggtgacccaagatggcgacatgatctttctatcggaaaacatcagcaagttcatggga
ctcacacaggtggagctaacaggacacagtatctttgacttcactcatccctgtgaccac
gaggagattcgtgagaacctgagtctcaaaaatggctctggttttgggaagaaaggcaaa
gacatgtccacagagcgggacttcttcatgaggatgaaatgcaccgtcaccaacagaggc
cggaccgtcaacctcaagtcagccacctggaaggtcttgcactgcaccggccaggtgaag
gtgtacaacagctgcccccctcacagtagtctgtgcagcttcaaggagcccctgctctcc
tgcctcatcatcatgtgcgaacccatccagcacccatcccacatggacatccccctggac
agcaagaccttcctgagccgccacagcatggacatgaagttcacctactgtgacgacaga
atcacagaactgattggttaccaccctgaggagctgctcggccgctcagcctacgagttc
taccatgccctggactcagagaacatgaccaaaagtcaccagaacctgtgcaccaaaggt
caggtggtgagtggccagtaccggatgcttgcaaagcatgggggctacgtgtggctggag
acccaggggacggtcatctacaaccctcgcaacctgcagccccagtgcatcatgtgtgtg
aactatgtcctgagcgagattgagaagaacgacgtggtgttctccatggaccagacggaa
tccctgttcaagccgcacctgacggccatgagtagcatctttgacagcagcagtgaggtg
gctgtgtctgagcagagtgactacctgttcaccaagctgaaggaggagccggaggagctg
gcccagctggcccccactgcgggggatgccatcattgccctggatttcgggagccagaac
tttgagaagtcctcagcctacagcagtgcccttctgcccccgagccagccgtggtccaga
gagctgaggagccacagcacccagagtgaggccgggagcctgcccgccttcaccgtgccc
caagcggctgcctccgggagcgccaccccaagtgccaccagcagcagcagctgctccacg
cccagcagccccggagactattacacatctctgaatgatgatctgaagattgaagtgatc
gagaagctcttcaccatagatacagaggcaaaggaccagggcagcacccagacggacttc
agtgagctggacttggagaccctggccccctacatccccatggacggggaagacttccag
ctcagtcccatctgccccgaggagaggcttctgcaggagaagccccagtcgactccccag
cactgcttcagcaccatgacgaacatcttccagccgctggcacctgtggcctcccacagc
cctttcctcctggacaagtatcaacagcagctgggaagcaagaagatagagcctgagcac
cggcccctgtcctccatcttctttgatggcggcagtaaagtgtccctgcccgcgtgctgt
ggccaagccggcacccctctctcctccctgggaggcaggtccagcagcacacagtggccc
cctgatccgccattacattttgggcccacgaagtggcctgttgtggatcagcacacggag
tccttggggccatcaccgttggggccccccgtcaactcgccccatctctccgtcttcaag
aaaaagtctgcaaaaggctttgggccccagggcccggatgtgatgagcccggccatggta
gccctgtccaacaagctgaagctgaagcgacagcgagaatatgaggagcaggccttccag
gacctgagcgggatccagggggacccatcaggcagcagcacttcacatcagatgtggaaa
aggatgaagagcctcaggggcagcgtgaactgccctttggtgcccgacaagttgctgagc
gcaagcccccccagtgatgagttcacccaacttcccatgaggggtgcgggacagcctctg
agacatctgccaccgccgccgtctgccatgagccccagggagaacaccaagagtgggttc
cccccacagtgctacgcaccccagtaccaggactacagcctgccgtcagctcccaaggtg
tcaggcatggcgagtcggctgcttgggccctcctttgagccctacctgctgcccgaattg
accagatatgactgtgaggtgaatgttcctgtgccaggaagctccacgctcctgcaagga
ggggacctcctcagagccctggaccaggccacctga
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