KEGG   Panthera leo (lion): 122217892
Entry
122217892         CDS       T10741                                 
Symbol
IL2
Name
(RefSeq) interleukin-2
  KO
K05429  interleukin 2
Organism
plez  Panthera leo (lion)
Pathway
plez04060  Cytokine-cytokine receptor interaction
plez04061  Viral protein interaction with cytokine and cytokine receptor
plez04151  PI3K-Akt signaling pathway
plez04625  C-type lectin receptor signaling pathway
plez04630  JAK-STAT signaling pathway
plez04658  Th1 and Th2 cell differentiation
plez04659  Th17 cell differentiation
plez04660  T cell receptor signaling pathway
plez04672  Intestinal immune network for IgA production
plez04940  Type I diabetes mellitus
plez05135  Yersinia infection
plez05142  Chagas disease
plez05162  Measles
plez05166  Human T-cell leukemia virus 1 infection
plez05171  Coronavirus disease - COVID-19
plez05200  Pathways in cancer
plez05320  Autoimmune thyroid disease
plez05321  Inflammatory bowel disease
plez05330  Allograft rejection
plez05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:plez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    122217892 (IL2)
   04151 PI3K-Akt signaling pathway
    122217892 (IL2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    122217892 (IL2)
   04061 Viral protein interaction with cytokine and cytokine receptor
    122217892 (IL2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    122217892 (IL2)
   04660 T cell receptor signaling pathway
    122217892 (IL2)
   04658 Th1 and Th2 cell differentiation
    122217892 (IL2)
   04659 Th17 cell differentiation
    122217892 (IL2)
   04672 Intestinal immune network for IgA production
    122217892 (IL2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122217892 (IL2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122217892 (IL2)
   05171 Coronavirus disease - COVID-19
    122217892 (IL2)
   05162 Measles
    122217892 (IL2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    122217892 (IL2)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    122217892 (IL2)
  09163 Immune disease
   05320 Autoimmune thyroid disease
    122217892 (IL2)
   05321 Inflammatory bowel disease
    122217892 (IL2)
   05330 Allograft rejection
    122217892 (IL2)
   05332 Graft-versus-host disease
    122217892 (IL2)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    122217892 (IL2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:plez04052]
    122217892 (IL2)
   00536 Glycosaminoglycan binding proteins [BR:plez00536]
    122217892 (IL2)
Cytokines and neuropeptides [BR:plez04052]
 Cytokines
  Interleukins
   122217892 (IL2)
Glycosaminoglycan binding proteins [BR:plez00536]
 Heparan sulfate / Heparin
  Cytokines
   122217892 (IL2)
SSDB
Motif
Pfam: IL2 Leg1
Other DBs
NCBI-GeneID: 122217892
NCBI-ProteinID: XP_042791513
UniProt: A0A8C8X6A9
LinkDB
Position
B1:101518244..101522773
AA seq 154 aa
MYKIQLLSCIALTLILVTNSAPASSSTKETQQQLEQLLLDLRLLLNGVNNPENPKLSRML
TFKFYVPKKATELTHLQCLVEELKPLEEVLYLAQSKNFHLNHIKELMSNINVTVLKLKGS
ETRFTCKYDDETATIVEFLNKWITFCQSIFSTLT
NT seq 465 nt   +upstreamnt  +downstreamnt
atgtacaaaattcaactcttgtcttgcattgcactgactcttatactcgtcacaaacagt
gcacctgcttcaagctctacaaaggaaacacagcaacagctggagcaattactgctggat
ttacggttgcttttgaatggagttaataatcctgagaaccccaaactctccaggatgctc
acatttaaattttacgtgcccaagaaggccacagaattgacacatcttcagtgtctagta
gaagaactcaaacctctggaggaagtgctatatttagctcaaagcaaaaactttcacttg
aatcacatcaaggaattaatgagcaatatcaatgtaacagttctgaaactaaagggatct
gaaacaagattcacatgtaaatatgatgatgagacagcaaccattgtagaatttctgaac
aaatggattaccttttgtcaaagcatcttctcaacactgacttga

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