Panthera leo (lion): 122218010
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Entry
122218010 CDS
T10741
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
KO
K04348
serine/threonine-protein phosphatase 2B catalytic subunit [EC:
3.1.3.16
]
Organism
plez Panthera leo (lion)
Pathway
plez04010
MAPK signaling pathway
plez04020
Calcium signaling pathway
plez04022
cGMP-PKG signaling pathway
plez04114
Oocyte meiosis
plez04218
Cellular senescence
plez04310
Wnt signaling pathway
plez04360
Axon guidance
plez04370
VEGF signaling pathway
plez04380
Osteoclast differentiation
plez04625
C-type lectin receptor signaling pathway
plez04650
Natural killer cell mediated cytotoxicity
plez04658
Th1 and Th2 cell differentiation
plez04659
Th17 cell differentiation
plez04660
T cell receptor signaling pathway
plez04662
B cell receptor signaling pathway
plez04720
Long-term potentiation
plez04724
Glutamatergic synapse
plez04728
Dopaminergic synapse
plez04921
Oxytocin signaling pathway
plez04922
Glucagon signaling pathway
plez04924
Renin secretion
plez05010
Alzheimer disease
plez05014
Amyotrophic lateral sclerosis
plez05020
Prion disease
plez05022
Pathways of neurodegeneration - multiple diseases
plez05031
Amphetamine addiction
plez05152
Tuberculosis
plez05163
Human cytomegalovirus infection
plez05166
Human T-cell leukemia virus 1 infection
plez05167
Kaposi sarcoma-associated herpesvirus infection
plez05170
Human immunodeficiency virus 1 infection
plez05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
plez05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122218010 (PPP3CA)
04310 Wnt signaling pathway
122218010 (PPP3CA)
04370 VEGF signaling pathway
122218010 (PPP3CA)
04020 Calcium signaling pathway
122218010 (PPP3CA)
04022 cGMP-PKG signaling pathway
122218010 (PPP3CA)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
122218010 (PPP3CA)
04218 Cellular senescence
122218010 (PPP3CA)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
122218010 (PPP3CA)
04650 Natural killer cell mediated cytotoxicity
122218010 (PPP3CA)
04660 T cell receptor signaling pathway
122218010 (PPP3CA)
04658 Th1 and Th2 cell differentiation
122218010 (PPP3CA)
04659 Th17 cell differentiation
122218010 (PPP3CA)
04662 B cell receptor signaling pathway
122218010 (PPP3CA)
09152 Endocrine system
04922 Glucagon signaling pathway
122218010 (PPP3CA)
04921 Oxytocin signaling pathway
122218010 (PPP3CA)
04924 Renin secretion
122218010 (PPP3CA)
09156 Nervous system
04724 Glutamatergic synapse
122218010 (PPP3CA)
04728 Dopaminergic synapse
122218010 (PPP3CA)
04720 Long-term potentiation
122218010 (PPP3CA)
09158 Development and regeneration
04360 Axon guidance
122218010 (PPP3CA)
04380 Osteoclast differentiation
122218010 (PPP3CA)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
122218010 (PPP3CA)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
122218010 (PPP3CA)
05170 Human immunodeficiency virus 1 infection
122218010 (PPP3CA)
05163 Human cytomegalovirus infection
122218010 (PPP3CA)
05167 Kaposi sarcoma-associated herpesvirus infection
122218010 (PPP3CA)
09171 Infectious disease: bacterial
05152 Tuberculosis
122218010 (PPP3CA)
09164 Neurodegenerative disease
05010 Alzheimer disease
122218010 (PPP3CA)
05014 Amyotrophic lateral sclerosis
122218010 (PPP3CA)
05020 Prion disease
122218010 (PPP3CA)
05022 Pathways of neurodegeneration - multiple diseases
122218010 (PPP3CA)
09165 Substance dependence
05031 Amphetamine addiction
122218010 (PPP3CA)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122218010 (PPP3CA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
plez01009
]
122218010 (PPP3CA)
Enzymes [BR:
plez01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
122218010 (PPP3CA)
Protein phosphatases and associated proteins [BR:
plez01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Calcineurin (PPP3/ PP2B)
Catalytic subunits
122218010 (PPP3CA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Metallophos
Motif
Other DBs
NCBI-GeneID:
122218010
NCBI-ProteinID:
XP_042791754
LinkDB
All DBs
Position
B1:120375841..120701101
Genome browser
AA seq
544 aa
AA seq
DB search
MRYFTLFFFSRIRCSKSSSYFVGVQLISVWTRWFSRVQRPYVAGQLDRTDLQAVPFPPSH
RLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTV
CGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLL
RGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIN
TLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCE
FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN
VMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSEEDGFDGA
TAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSA
IKGFSPQHKITSFEEAKGLDRINERMPPRRDAMPSDANLNSINKALATETNGTDSNGSNS
SNIQ
NT seq
1635 nt
NT seq
+upstream
nt +downstream
nt
atgagatattttacactcttttttttttctcgtatcaggtgctctaaatccagttcatat
tttgtaggcgtacagctcatctcagtttggaccaggtggttttcacgtgttcagcggcca
tatgttgctggtcaattggacagaacagatttacaggctgtcccatttcctccaagtcac
cgacttacagcaaaagaagtattcgataacgatgggaagcctcgtgtggatatcttaaag
gcacatctcatgaaggagggcagactggaagagagcgttgcattgagaataataacagag
ggggcctcaattcttcgacaggaaaaaaatttgctggatatcgatgcaccagtcacagtt
tgtggggacatccatggacaattctttgatttgatgaagctttttgaagtggggggatct
cctgccaacactcgctacctcttcttaggggactatgttgacagagggtacttcagtatc
gaatgtgtgctgtatttgtgggccttgaaaattctttaccccaaaacactgtttttactt
cgtggaaatcatgaatgtagacatctaacagagtatttcacatttaaacaagaatgtaaa
ataaagtattcagaacgcgtatatgatgcctgtatggatgcctttgactgcctgcccctg
gctgccctgatgaaccaacagttcctgtgtgtacacggcggtttgtctccagagattaac
actttagatgatatcagaaaattagaccgattcaaagaaccacctgcttacggacctatg
tgtgatatcctgtggtcagaccccctggaggattttggaaatgagaagactcaggaacat
ttcactcacaacacagtcagggggtgttcgtacttctacagctacccggctgtatgtgaa
ttcttacagcacaataacctgttgtctatactccgagcccatgaagcccaagatgcaggg
tatcgcatgtacaggaaaagccaaacgacaggcttcccttctctaattacaattttttca
gcaccaaattacttagatgtgtacaataacaaagctgcagtattgaagtatgagaacaat
gtcatgaacatcaggcaattcaactgttctcctcacccatactggcttccaaatttcatg
gatgttttcacttggtccctgccctttgttggagaaaaagtgactgaaatgctggtaaat
gtcctcaacatctgctcagatgatgaactagggtcagaagaagatggatttgatggcgca
acagctgcagcccggaaggaggtgataaggaacaagatccgagcaataggcaaaatggcc
cgagtgttctcagttctcagagaagagagtgagagcgtgctaacgctgaaaggcttgact
cccacgggcatgctccccagcggagtgctttctggagggaagcagaccctgcaaagcgcc
atcaaaggattttcaccacaacataagatcactagcttcgaggaggccaagggcttagac
cgaattaacgagaggatgccacctcgcagagatgccatgccctctgacgccaaccttaac
tccatcaacaaggctctcgccacagagactaacggcacggacagcaatggcagtaatagc
agcaatatccagtga
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