Panthera leo (lion): 122218226
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Entry
122218226 CDS
T10741
Symbol
KDR
Name
(RefSeq) vascular endothelial growth factor receptor 2 isoform X1
KO
K05098
kinase insert domain protein receptor [EC:
2.7.10.1
]
Organism
plez Panthera leo (lion)
Pathway
plez01521
EGFR tyrosine kinase inhibitor resistance
plez04010
MAPK signaling pathway
plez04014
Ras signaling pathway
plez04015
Rap1 signaling pathway
plez04020
Calcium signaling pathway
plez04151
PI3K-Akt signaling pathway
plez04370
VEGF signaling pathway
plez04510
Focal adhesion
plez05205
Proteoglycans in cancer
plez05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122218226 (KDR)
04014 Ras signaling pathway
122218226 (KDR)
04015 Rap1 signaling pathway
122218226 (KDR)
04370 VEGF signaling pathway
122218226 (KDR)
04020 Calcium signaling pathway
122218226 (KDR)
04151 PI3K-Akt signaling pathway
122218226 (KDR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
122218226 (KDR)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
122218226 (KDR)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
122218226 (KDR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122218226 (KDR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122218226 (KDR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
plez04090
]
122218226 (KDR)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122218226 (KDR)
Protein kinases [BR:
plez01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
122218226 (KDR)
CD molecules [BR:
plez04090
]
Proteins
122218226 (KDR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
VEGFR1-3_N_Ig-like
Ig_3
I-set
Pkinase
Ig_2
ig
VEGFR-1-like_Ig-like
Ig_VEGFR-1-like_5th
VEGFR-2_TMD
V-set
C2-set_2
Ig_4
BppU_N
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
122218226
NCBI-ProteinID:
XP_042792296
LinkDB
All DBs
Position
B1:160831612..160877865
Genome browser
AA seq
1443 aa
AA seq
DB search
MVVFPLPARGITCAQKAQSCSAAGISSPPGTRRRPCKSWPEPEHPPLCASQSCAAARVPP
PRLLRRQARGERTGARVLGRALGARCGMESKALLAVVLWFCVETRAASVGLPSVSLDPPR
LSIQKDILTIMANTTLQITCRGQRDLDWLWPNNQSGSEKRVEVTDCSDSFFCKTLTIPKV
IGNDTGAYKCFYQDTDVASVIYVYVQDYRSPFIASVSDQHGVVYITENKNKTVVIPCLGS
ISNLNVSLCARYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIM
YIVVVVGYKIYDVVLSPPHGVELSVGERLVLNCTARTELNVGIDFNWEYPSLKHQHKKLV
NRDLKTQSGSEMKKFLSTLTIDGVTRSDQGWYTCAASSGLMTKRNSTFVRVHEKPFVAFG
SGMESLVEAIVGDRVRVPVKYLGYPPPEIKWYKNGRPIESNHTIKVGHVLTIMEVSEKDT
GNYTVILTNPISKEKQSHVVSLVVNVPPQIGEKSLISPVDSYQYGTTQTLTCTVYAVPPP
HHIRWYWQLEEECAYRPAQAVLMTNPYTCKEWRNVDDFQGGNKIEVNKNQFALIEGKNKT
VSTLVIQAANVSALYKCEAVNKAGRGERVISFHVTRGPEITLQPGTQPTEQERVSLWCTA
DRTTFENLTWYKAGSQALPVHVGELPTPICKNLDALWKMNATTFSNGTSDTLILELQNAS
LQDQGDYVCFAQDRKTKKRHCVVRQLTVLERVAPMITGNLENQTTSIGETIEVSCTTSGN
PPPQITWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCRACSVLGCAKVEAFFI
VEGAQEKTNLEVIILVGTAVIAMFFWLLLVIVLRTVKRANGGELKTGYLSIVMDPDELPL
DEHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCKTVAVKMLKEG
ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRGKRN
EFVPYKTKGARFRQGKEYVGEITMDPKRRLDSITSSQSSASSGFVEEKSLSDVEEEEVSE
DLYKNFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDI
YKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDE
EFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDGK
DYIVLPISETLSMEEDSGLSLPTSPVSCMEEEEVCDPKFHYDNTAGISQYLQNSKRKSRP
VSVKTFEDIPLEEPEVKVIPDDSQTDSGMVLASEELKTLEDRTKLAPSFSGLMPSKSKES
VASEGSNHTSGYQSGYHSDDTDTTVYSSEEAELLKLVEIGPQAGSAAQILQPDSGPALGS
PPV
NT seq
4332 nt
NT seq
+upstream
nt +downstream
nt
atggttgtgtttcctctgcccgcgcggggcatcacttgcgcgcagaaagcccagagctgt
agcgcagccgggatttcctctcctcctggcacccgcagacgcccctgcaagtcgtggccg
gagccagagcaccctcccctttgcgcctcacagtcctgcgctgcggcgcgcgttccacct
ccgcgccttcttcgccggcaggcccggggagaaagaaccggcgcccgagttctgggcagg
gcgctcggcgcgaggtgcgggatggagagcaaggcgctgctggccgtcgttctgtggttc
tgcgtggagacccgggctgcctctgtgggtttgcctagtgtttcccttgatccacccaga
ctcagcatacaaaaagacatacttacaattatggctaatacaactcttcagattacttgc
aggggacagagggacttggactggctctggcccaacaatcagagtggctctgagaagaga
gtggaggtgacggactgcagtgacagcttcttctgtaagacgctcacgattccaaaagtg
atcggaaatgatactggagcctacaagtgcttctaccaggacactgacgtagcctcggtc
atttatgtctatgttcaagattacaggtctccatttattgcttctgttagcgaccaacat
ggcgttgtgtacatcactgagaacaaaaacaaaactgtggtgattccatgtcttgggtcc
atttccaacctcaatgtgtcactttgtgcaaggtatccagaaaagaggtttgtccctgat
ggtaacagaatttcctgggacagtaagaaaggctttactatccccagctacatgatcagc
tatgctggcatggtcttctgtgaagcaaaaattaatgatgaaagttaccagtctattatg
tacatagttgtggttgtagggtacaagatttatgatgtggttctgagcccccctcatgga
gttgagctgtctgttggagagaggctcgtcttaaactgtacagcgaggactgaactaaat
gtggggattgacttcaactgggaatacccttctttgaagcatcagcataaaaagcttgtt
aaccgggacctaaaaactcaatctgggagtgagatgaagaaatttttgagcaccttgacc
atagatggtgtaacccggagtgaccaagggtggtatacctgtgcggcttccagtgggctg
atgaccaagcggaacagcacgttcgtcagggtccacgaaaaaccttttgtcgcttttggt
agtggcatggaatctttggtggaagccatcgtgggagaccgtgtcagagtgcctgtgaag
taccttggttaccctcccccggaaataaaatggtataaaaatggaagacccattgagtcc
aatcacacaataaaagtggggcatgtactgactattatggaagtgagtgaaaaagataca
ggaaattacactgtcatccttaccaaccccatttcgaaggagaaacagagccacgtggta
tctctggtcgtgaatgtcccaccccagatcggcgagaaatccctgatctctccggtggat
tcgtaccagtacggcaccacgcaaacgctgacgtgcacggtctacgcggtccccccgcca
catcacatccgctggtactggcagctggaggaggagtgtgcctacaggcctgcccaagct
gtcttaatgacaaacccatacacttgtaaagaatggagaaatgtggatgacttccagggg
ggaaataaaattgaagtcaacaaaaatcaatttgccctaattgaaggaaaaaacaaaact
gtaagtacccttgttatccaagcggcaaatgtgtcagctttgtacaaatgtgaagccgtc
aacaaagctgggagaggagagagggttatctccttccacgtgaccaggggccctgaaatc
actttgcagcccggcacccagccgaccgaacaggaacgggtgtctttgtggtgcactgca
gacagaactacatttgagaacctcacgtggtacaaggctggctctcaggctctgccagtc
cacgtgggagagctgcctacacccatctgcaagaacttggatgccctttggaaaatgaat
gccaccacgttctctaatggcacaagcgacactttgatcctggagctccagaacgcatcc
ttgcaggaccaaggagattatgtgtgctttgctcaggacaggaagaccaagaaaagacat
tgtgtggtccgacagctcacggttttagagcgtgtggcacccatgatcacaggaaacctg
gagaatcaaacaacaagtattggtgaaaccatcgaagtttcgtgcaccacgtctgggaat
ccccctccacagattacgtggtttaaagataatgaaacacttgttgaagactcaggtatt
gtactgaaagatgggaaccggaacctaaccatccgcagggtgaggaaggaagatgaaggc
ctgtatacgtgccgggcatgcagtgttcttgggtgtgcaaaagtggaggcatttttcatc
gtggaaggtgcccaggagaagacgaacttggaggtcattattctagtaggcacagcagtg
attgccatgttcttctggttattacttgtcatcgttctacggaccgttaagcgggccaat
ggaggggaactgaagacaggctacttgtccatcgtcatggatccagatgaactgcccttg
gatgaacactgtgaacgtctgccttatgatgccagcaagtgggaatttcccagagaccgg
ctgaaactaggtaagccccttggccgtggtgccttcggccaagtgatcgaagcagatgcc
tttggaattgacaagacagcgacttgcaagacagtggctgtcaaaatgttaaaagaagga
gccacacacagtgaacaccgagccctcatgtctgaactcaagatcctcattcatattggc
caccatctcaatgtggtcaatcttctaggtgcctgtaccaagccaggagggccactcatg
gtgattgtggaattttgcaagtttggaaacctgtcaacttacttaaggggcaagagaaat
gaatttgtcccttacaagaccaaaggggcacgatttcgtcaagggaaggaatatgttggg
gaaatcactatggatccgaaacgccgtttggatagtatcacgagtagtcagagctcagcc
agctctggatttgttgaggagaaatccctcagtgatgtggaggaagaggaagtttctgaa
gatctgtacaagaacttcctgaccttggagcatctcatctgttacagcttccaagtggct
aagggcatggagtttttggcgtcacggaagtgtatccacagggacctggcggcacgaaat
atcctcttgtcggagaagaacgtggttaaaatctgtgactttggcttggcccgggatatt
tataaagacccagattatgtcagaaaaggagatgctcgcctccctttgaaatggatggcc
ccagaaacgatttttgaccgagtgtacacaattcagagtgatgtgtggtcttttggtgtt
ttgctctgggaaatattttccttaggtgcttctccatatcctggagtaaagattgatgag
gaattttgtaggcgattgaaagaaggcactagaatgagggcccctgattataccacacca
gaaatgtaccagaccatgcttgactgctggcatggggagcccagtcagagacccacgttt
tctgagttggtggaacatttgggaaatctcttacaagctaatgctcagcaggatggcaaa
gactatattgttctcccgatatcagagactttgagcatggaagaggattctggactctct
ctgcctacctcacctgtttcctgtatggaggaagaggaagtgtgtgaccccaaattccat
tatgacaacacagcaggaatcagtcagtatctgcagaatagtaagcgaaagagccggccc
gtgagtgtaaaaacatttgaagatatcccgttggaagaaccagaagtaaaagtaatccca
gatgacagccagacggacagtggtatggttcttgcatcagaagagctgaaaaccttggaa
gacagaaccaaattagctccatcttttagtggactgatgcccagcaaaagcaaggagtcc
gtggcatccgaaggctccaaccacacgagtggctaccagtccgggtatcactccgacgac
acagacaccactgtgtactccagcgaggaggcagaacttttaaagctggtggagattgga
ccacaagctggcagtgcagcccagattctccagcctgactctggacccgcgttgggctct
cctcctgtttaa
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integrated database retrieval system
