Panthera leo (lion): 122218227
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Entry
122218227 CDS
T10741
Symbol
KIT
Name
(RefSeq) mast/stem cell growth factor receptor Kit
KO
K05091
proto-oncogene tyrosine-protein kinase Kit [EC:
2.7.10.1
]
Organism
plez Panthera leo (lion)
Pathway
plez04010
MAPK signaling pathway
plez04014
Ras signaling pathway
plez04015
Rap1 signaling pathway
plez04072
Phospholipase D signaling pathway
plez04151
PI3K-Akt signaling pathway
plez04640
Hematopoietic cell lineage
plez04916
Melanogenesis
plez05200
Pathways in cancer
plez05221
Acute myeloid leukemia
plez05224
Breast cancer
plez05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122218227 (KIT)
04014 Ras signaling pathway
122218227 (KIT)
04015 Rap1 signaling pathway
122218227 (KIT)
04072 Phospholipase D signaling pathway
122218227 (KIT)
04151 PI3K-Akt signaling pathway
122218227 (KIT)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
122218227 (KIT)
09152 Endocrine system
04916 Melanogenesis
122218227 (KIT)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122218227 (KIT)
05230 Central carbon metabolism in cancer
122218227 (KIT)
09162 Cancer: specific types
05221 Acute myeloid leukemia
122218227 (KIT)
05224 Breast cancer
122218227 (KIT)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122218227 (KIT)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
plez04090
]
122218227 (KIT)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122218227 (KIT)
Protein kinases [BR:
plez01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
122218227 (KIT)
CD molecules [BR:
plez04090
]
Proteins
122218227 (KIT)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
C1-set
C2-set_2
Motif
Other DBs
NCBI-GeneID:
122218227
NCBI-ProteinID:
XP_042792298
LinkDB
All DBs
Position
B1:complement(161132716..161219294)
Genome browser
AA seq
974 aa
AA seq
DB search
MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGERSLPSIHPATSELIVSVGDEIRLLCTD
PGFVKWTFETLGQSSEITHNEWITEKAEATNTGNYTCTNGGGLSSSIYVFVRDPTKLFLV
DLPLYGKEDHDTLVRCPLTDPEVTNYSLRGCEGKPLPKDLTFVTDPKAGITIRNVKREYH
RLCLHCSADRKGKSVLSKKFTLKVRAAIRAVPVVSVSKASHLLREGEEFSVMCLIKDVSS
SVDSMWIKENSPQTNAQPQSNSWHQGDFNFVRQERLTISSARVNDSGVFMCYANNTFGSA
NVTTTLEVVAKGFIHIFPMMNTTIFVNDGENVDLIVEYEAYPKPEHQRWVYMNRTLTDKW
EDYPKSDNESNIRYVSELHLTRLKGNEGGTYTFQVSNSDVNSSVTLNVYVNTKPEILTHE
SLVSGILQCLVAGFPEPTVDWYFCPGTEQRCPVPVGPLDVQMQNSSVSPSGKLVVQSSID
YSAFKHNGTVECRASNNVGKTSAFFNFAFKEQMHPHTLFTPLLIGFVIAAGMMCIIVMIL
TYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKV
VEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVG
GPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEVALYKNLLQSKESSCNDSTNEYMD
MKPGVSYVVPTKADKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFL
ASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFN
CVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIM
KTCWDADPLKRPTFKQIVQLIEKQISDSTNHIYSNLANCSPNRERPTAVDHCVRINSVGS
STSSTQPLLVHEDA
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atgagaggcgctcgcggcgcctgggattttctctgcgtcctgctcctcctgctccgcgtc
cagacaggctcttctcaaccatctgtgagtccaggggaacggtctctaccatccatccat
ccagcaacatcagagttaatagtcagtgttggcgacgagattaggctgttgtgcaccgat
ccaggatttgtcaaatggacttttgagaccctgggccagtcgagtgagatcacacacaat
gaatggatcacggagaaagcagaggccaccaacacaggcaattacacgtgcaccaacgga
ggcggcttaagcagttccatttacgtgtttgttagagatcccacaaagcttttcctcgtt
gaccttcccttgtatgggaaagaagaccatgatacgctggtccgctgtcctctgacagac
ccagaggtgaccaattactccctccgggggtgcgaggggaagcctcttcccaaggacttg
actttcgtcaccgatcccaaggctggcatcacaatcaggaacgtgaagcgcgagtaccat
cggctgtgcctgcattgctctgcggaccggaagggcaagtccgtgctgtcgaagaaattc
accctgaaagtgagggcagccatcagagctgtcccagttgtgtctgtgtccaaagcaagc
catcttcttagggaaggggaagaattctccgtgatgtgcttgataaaagatgtgtctagt
tccgtggactcgatgtggatcaaggaaaacagcccgcaaactaacgcacagccacagagt
aatagctggcaccaaggtgacttcaattttgtacgtcaggaaaggttgacgatcagctca
gcaagagttaacgattctggagtgttcatgtgttatgccaataatacttttggatcggca
aatgtcacaacaaccttggaagtcgtagctaaaggattcattcacatcttcccgatgatg
aataccacaatattcgtgaatgacggagagaatgtggatctgattgtcgaatatgaggca
tatcccaagcctgagcaccaacggtgggtctatatgaacagaaccctcactgataaatgg
gaagattatcccaagtctgacaacgaaagtaatatcagatatgtgagtgaacttcaccta
accagattaaaagggaacgaaggaggcacttacacgtttcaagtgtccaattccgatgtc
aattcttccgtgacattgaatgtttacgtgaacacaaaaccagaaatcctgactcatgaa
agtctcgtgagtggcatactacagtgtttggtagctggattcccggagcccacagtagat
tggtatttttgtccaggaactgagcagagatgtcctgttcctgttgggccactggatgtg
cagatgcaaaactcatctgtatcgccgtctggaaaactagtggttcaaagttccatcgat
tacagtgctttcaaacacaatggcacagtcgagtgtagggcttccaacaatgtgggcaag
acttctgccttttttaactttgcatttaaagaacaaatgcatcctcacaccctgttcaca
cctttgctgattggttttgtgatcgcagctggtatgatgtgtattatcgtgatgatactt
acctacaaatatttacagaaacccatgtatgaagtgcagtggaaggttgtcgaggagata
aatggaaacaattatgtttacatagacccaacacagcttccttacgatcacaaatgggag
tttcccagaaacaggctgagttttgggaaaaccttgggtgccggtgccttcgggaaggtg
gttgaggccactgcatatggcctgattaagtcggatgcagccatgaccgttgccgttaag
atgctcaaaccaagtgcccatttaaccgaacgagaagccctcatgtccgagctcaaagtc
ttgagttacctcggcaatcacatgaatattgtgaatcttctcggagcatgcaccgttgga
gggcccaccctggtcattactgagtattgttgctatggtgatcttttgaattttttgaga
agaaaacgcgattcatttatttgctcaaagcaggaagatcatgcagaagtggcactttat
aagaaccttctgcagtcaaaggagtcttcctgcaacgatagtactaatgagtacatggac
atgaaacccggcgtttcttatgttgtgccaaccaaggcagacaaaaggagatccgccaga
ataggctcatacatagaaagagatgtgactcccgccatcatggaggacgatgagttggct
ctagacctggaggacttgctgagcttctcgtaccaagtggccaagggcatggcattcctc
gcctcgaagaattgtattcacagagacttggctgctagaaatatcctccttactcatggt
cgaatcacaaagatttgtgattttggtctagccagagacatcaagaatgattctaattat
gtggtcaaaggaaacgctcggctacctgtgaagtggatggcacctgaaagcattttcaac
tgtgtgtacacatttgaaagtgatgtctggtcctatgggatttttctgtgggagctgttc
tctttaggaagcagcccctaccctggaatgccagtcgactctaagttctacaagatgatc
aaggaagggttccgaatgctcagccctgagcacgcacctgctgaaatgtatgacataatg
aagacttgctgggatgctgatcccctgaaaaggccaacattcaagcagatcgtgcagcta
atcgagaagcagatttcagatagcaccaatcatatttattccaacttagcaaactgcagc
ccgaaccgggagcgccccacagcggtggaccattgtgtgcggatcaattctgtgggcagc
agcacatcttctacccagcctctgctggtccacgaggatgcctga
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