Panthera leo (lion): 122218589
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Entry
122218589 CDS
T10741
Symbol
NRG2
Name
(RefSeq) pro-neuregulin-2, membrane-bound isoform isoform X1
KO
K05456
neuregulin 2
Organism
plez Panthera leo (lion)
Pathway
plez01521
EGFR tyrosine kinase inhibitor resistance
plez04012
ErbB signaling pathway
plez05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
122218589 (NRG2)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
122218589 (NRG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122218589 (NRG2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
plez04052
]
122218589 (NRG2)
Cytokines and neuropeptides [BR:
plez04052
]
Cytokines
Growth factors (RTK binding)
122218589 (NRG2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Neuregulin
NRG2_N
I-set
Ig_3
ig
Ig_2
EGF_Epiregulin
Ig_VEGFR-1-like_5th
Ig_6
EGF_TGFA-like
Gurken_M
C2-set_2
V-set
Zwei_Ig_N
EGF
EGF_2
Motif
Other DBs
NCBI-GeneID:
122218589
NCBI-ProteinID:
XP_042792762
LinkDB
All DBs
Position
A1:complement(115895284..116080149)
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AA seq
851 aa
AA seq
DB search
MRQVCCSALPPPPLEKARCSSYSDSSSSSGSSSSSSGSSSGSSERSSSSSSSKSSSRSSS
SSNSSISRPAAPPEPRPPQQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSL
ACYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLR
SGGLQREQVISVGSCAPLERNQRYIFFLEPTEQPLVFKTAFAPIDTNGKNLKKEVGKILC
TDCATRPKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNG
RKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLHVNSVSTTLSSWSGHARKCNETAK
SYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEELYQKRVLTIT
GICVALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQM
ADYISKNVPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLT
SDSQSGIMLSSVGTSKCNSPACVEARARRAAAYSLEERRRAAVPPYHDSVDSLRDSPHSE
RYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQQPLLRQ
PAPPGPGPGPGADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETT
QECAPPPPPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASG
SDDDADGALAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGP
PPRGKQDSAPL
NT seq
2556 nt
NT seq
+upstream
nt +downstream
nt
atgcggcaggtttgctgctcagcgctgccgccgccgccactggagaaggctcggtgcagc
agctacagcgacagcagcagcagcagcggcagcagcagcagcagcagcggcagcagcagc
ggcagcagcgagaggagcagcagcagcagcagcagcaagagcagcagcaggagcagcagc
agcagcaacagcagcatctcccgtcccgctgcgcccccagagccgcggccgccgcaacag
ccgcagccccgcagccccgcagcccggagagccgccgcccgctctcgagccgcagccgcc
ggcggcatgaggcgcgacccggcccccggcttctccatgctgctcttcggtgtgtcgctc
gcctgctactcgcctagcctcaagtcggtgcaggaccaggcgtataaggcacccgtggtg
gtggagggcaaggtacaggggttagccccggccggcggctccagctccaacagcacccga
gagccgcccgcctcgggtcgggtggcgctggtaaaggtgctggacaagtggccgctccgg
agcgggggtctgcagcgcgagcaggtgatcagcgtgggctcctgtgcgccgctagaaagg
aaccagcgctacatctttttcctggagcccacggagcagcccttagtgtttaagacggcc
tttgcccccatcgacaccaacggcaaaaacctcaagaaagaggtgggcaagatcctgtgc
actgactgcgccacccggcccaagctgaagaagatgaagagccagacgggacaggtgggt
gagaagcaatcactgaagtgtgaggcagcagcgggcaaccctcagccctcctatcgctgg
ttcaaggatggcaaggagctcaaccgcagccgtgacattcgcatcaagtacggcaacggc
agaaagaactcacgactacagttcaacaaggtgaaggtggaggacgctggggagtatgtc
tgcgaggctgagaacatcctggggaaggacacggtccggggccggctccatgtcaacagc
gtgagtaccactctatcatcatggtcggggcacgcccggaagtgcaacgagacggccaag
tcctattgtgtcaatggaggcgtctgctactacatcgagggcatcaaccagctctcctgc
aaatgtccaaacggattcttcggacagagatgtttggagaaactgcctttgcgattgtac
atgccagatcctaagcaaaaagccgaggagctgtaccagaagagggtcctgactatcacc
ggtatctgcgtggctctgctggtcgtgggcattgtctgcgtggtcgcctactgcaagact
aaaaaacagcggaagcagatgcacaatcacctccggcagaacatgtgcccagcccaccag
aatcggagcttggccaacgggcccagccacccccggctggaccctgaggagatccagatg
gcagattatatctccaagaatgtgccagccacagaccatgtcatccggagggaaacggag
accaccttctctgggagccactcctgttctccttctcaccactgttccacagccacaccc
acctccagccacaggcatgagagccacacgtggagcctggaacgttctgaaagcctgacc
tctgactcccagtcgggcatcatgctgtcatcggtgggcaccagcaagtgcaacagccca
gcgtgtgtggaggcccgggcacggcgggcagcggcctacagcctggaggagcggcgcagg
gctgccgtgccaccttaccacgactccgtagactctctgcgtgactccccacatagcgag
aggtacgtgtcggcactgaccacgcccgcgcgcctctctccagtggacttccactactcg
ctggccacgcaggtgccgacttttgagatcacgtcccccaactccgctcacgcagtgtcg
ctgccgccggccgcacccatcagctaccgcctggcggagcagcagccgcttctgcggcag
ccggcgccccctggccccgggccgggacccggcgcggacatgcagcgcagctacgacagc
tactactaccccgcggcggggcccgggccgcggcgcggggcctgcgcgctgggcggcagc
ctgggcagcctgcccgccagccccttccgcatcccggaggacgacgagtacgagaccacg
caggagtgcgcgccccctcccccaccgcggccgcgcgcccgcggcgcgtcccgcaggacg
tcggcggggccccggcgctggcgccgctcgcgcctcaacgggctggcggcgcagcgcgca
cgcgcggcgcgggactcgctgtcgctgagcagcggctcgggtggcggctcggcctcaggc
tcggacgacgacgcggacggggcgctggcggccgagagtacgcctttcctcggcctgcgc
gcggcgcacgatgcgctgcgctcggactcgccgccgctgtgcccggcggccgacagcagg
acttactactccctggacagccacagcacgcgggccagcagcagacacagccgcgggccc
cccccgcggggcaagcaggactcggcgcccctctag
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