Panthera leo (lion): 122218669
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Entry
122218669 CDS
T10741
Symbol
GRK4
Name
(RefSeq) G protein-coupled receptor kinase 4
KO
K08291
G protein-coupled receptor kinase [EC:
2.7.11.16
]
Organism
plez Panthera leo (lion)
Pathway
plez04062
Chemokine signaling pathway
plez04144
Endocytosis
plez05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122218669 (GRK4)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
122218669 (GRK4)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122218669 (GRK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122218669 (GRK4)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.16 G-protein-coupled receptor kinase
122218669 (GRK4)
Protein kinases [BR:
plez01001
]
Serine/threonine kinases: AGC group
GRK family [OT]
122218669 (GRK4)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RGS
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
122218669
NCBI-ProteinID:
XP_042792968
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All DBs
Position
B1:complement(202753229..202849822)
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AA seq
578 aa
AA seq
DB search
MELENLLANTLLLKARQGGYGKKRGRSKKWKEMLKLPPVSQCSELRCSIEKDYNSLCDKQ
PIGRLLFRQFCDTRHDLKIYIKFLDVVAEYEVADDEDRRSYGLSILDTFFSAAEKSAAPL
PEIPSRVLKECRLRLKENPSKDVFEECTRFVHNYLSGEPFEEYQESSYFSRFLQWKWLER
QPITKDTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLAKKRIKRRKGEAMALNEKRML
EKVNSRFVVSLSYTYETKDSLYLVLTIMNGGDLKYHIYNLGSPGFDEQRAIFYAAELCCG
LEDLQKERIVYRDLKPENILLDDIGHIRISDLGLAVEVPEGRTVRGRVGTVGYMAPEVIN
NENYTFSPDWWGLGCLIYEMIQGHSPFKKFKEKVKRQEVERRVKKDTEEYSRKFSEDAKS
VCRMLLTKNPRQRLGFSGGAAEVKGHPVFKDINFKKLEANMLDPPFCPDPKAVYCKDVVD
IDQFSTVRGVYLDTTDDTFYSQFATGSVSIPWQNEMIESGCFKDINESDTGECVALHLQE
TLCHPVPKAKRGFFYRLLRRGGCISGVPSDKEELSSMV
NT seq
1737 nt
NT seq
+upstream
nt +downstream
nt
atggagcttgagaacctcttggccaacacgctgctgctgaaagcgcgccaaggaggatat
ggcaaaaaaagaggtcgtagtaaaaaatggaaggaaatgctgaagctgccccctgtcagc
cagtgcagcgagcttagatgttccattgaaaaggattataacagcctttgtgacaagcag
ccaataggaagacttctcttcaggcaattctgtgatacaagacatgatctaaagatatac
atcaaattcctagacgtagtggcagaatatgaagtggctgatgacgaagaccgcagaagt
tacggactgtccatcttagacacgttcttcagtgctgctgagaaatcggcagccccttta
ccagaaataccttcacgtgttttgaaagaatgtaggttgagactgaaggagaacccctcc
aaggacgtctttgaggagtgcaccagatttgttcataactatttaagtggagaaccattt
gaagaatatcaagaaagttcatatttttctcgatttctacagtggaaatggctggaaagg
caaccaataacaaaggacacatttagacattacagagttctaggaaaaggcggatttggg
gaggtctgtgcctgtcaagtgcgagctacaggaaaaatgtacgcctgtaagaagctagca
aagaaaagaataaagaggaggaaaggtgaagcaatggctctaaatgagaagaggatgctg
gaaaaagtgaatagcagatttgtagttagtttgtcttatacttatgagaccaaagactcc
ttgtacttggtgctgaccattatgaatggaggggacttaaagtatcacatttacaacctg
ggcagccctggctttgatgagcagagagccatcttctatgcggccgaactgtgctgtggc
ttggaggacttacagaaagaaagaattgtgtacagagacttaaagcctgagaatatcctc
ctcgatgacattgggcacatccggatctcagacctgggtttagccgtggaggtcccggag
ggccggaccgtccgaggaagagtggggaccgtcggctacatggctcctgaagttatcaat
aatgaaaactatacatttagtcctgattggtggggacttggctgcctaatatatgagatg
attcagggacattctccattcaaaaagttcaaagagaaggtcaagcgacaggaagtcgag
cgcagagtgaagaaggacacagaggagtactccaggaagttttccgaggacgccaagtcc
gtctgcaggatgttactcaccaagaatcccagacaacggctgggcttcagcggtggagca
gcggaagtgaagggacaccccgtgttcaaggacattaacttcaagaagctggaagcaaat
atgttggatccccctttctgtcctgatccgaaggcagtgtattgtaaggatgtcgtggat
atcgaccagttctccacggtgaggggagtctacctggacaccacggacgatactttctac
agccaatttgccacaggctctgtctccatcccctggcagaacgagatgatcgaatcgggt
tgtttcaaggacatcaacgaaagtgacactggagaatgtgtggcactacatctacaagag
acactgtgccacccagttcccaaagcaaagagaggcttcttctatagactcctcagaaga
gggggctgcattagcggtgtccccagcgacaaggaagagctgtcctcaatggtgtga
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