Panthera leo (lion): 122218688
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Entry
122218688 CDS
T10741
Symbol
NSD2
Name
(RefSeq) histone-lysine N-methyltransferase NSD2 isoform X1
KO
K11424
[histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:
2.1.1.357
]
Organism
plez Panthera leo (lion)
Pathway
plez00310
Lysine degradation
plez01100
Metabolic pathways
plez05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
122218688 (NSD2)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
122218688 (NSD2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
plez03036
]
122218688 (NSD2)
Enzymes [BR:
plez01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.357 [histone H3]-lysine36 N-dimethyltransferase
122218688 (NSD2)
Chromosome and associated proteins [BR:
plez03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
122218688 (NSD2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PWWP
PHD-1st_NSD
SET
C5HCH
PHD_NSD
AWS
PHD
HMG_box
PHDvar_NSD
zf-HC5HC2H
HMG_box_2
zf-HC5HC2H_2
MUM1-like_PWWP
Motif
Other DBs
NCBI-GeneID:
122218688
NCBI-ProteinID:
XP_042793032
LinkDB
All DBs
Position
B1:complement(203714278..203803686)
Genome browser
AA seq
1352 aa
AA seq
DB search
MKQAPETLGSTNGKSQNCEVNRECSVFLSKAQLSTSLQEGVMQKFNGHDALPFIPSEKLK
DLTSRVFNGEPGAHDARLRFESQEVKALGTPPSTTPIKNGSPEIKLKITKTYMNGKPLFE
SSICGDSAAAVSQSEEHGQKPENKARRNRKRSIKYDSLLEHGLVEAALVSRISSPSDKKV
AAKKESCPNTGRDKDHLLKYSVGDLVWSKVSGYPWWPCMVSADPLLHNYTKLKGQKKSAR
QYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRA
QWETGIVQAEEAASMSVEERKAKFTFLYVGERLHLNPHVAKEAGISVEAPPLGPMVEPSG
VPEEAAADPKSMREEGVPVKRRRRVKLSSSAENRAGDPGTVQSTPQKMAEADPKRGVGSP
PGRKKATASAPRSRKGDAASQFLVFCQKHRDEVVAEHPDASAEEVKELLGSQWDMLNEKQ
KARYNTKFALVASPQSEEDSGNVNGKKRNHTKRTQDPPEDVEIEDAPRKRLRTDKHGLRK
RETASDKTARTGSCKAMEAATSLKSQAATKHLSDACKPLKKRNRASAAASCAPFSKSSSP
SASLTENEVSDGPGDEPAESPYESADETQTEASVSSKKSERGVAAKKEYVCQLCEKPGSL
LLCEGPCCGAFHLACLGLARRPEGRFTCSECASGIHSCFVCKESKTDVRRCVVSQCGKFY
HEACVRKYPLTVFESRGFRCPLHSCVTCHASNPSNPRPSKGKMMRCVRCPVAYHGGDACL
AAGCSVIASHSIICTSHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLS
IEMPDGSWFCNECRAGKKLHFQDVVWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFP
VFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREAR
ETQESERKPPPYKHIKVNKPYGKVQIHTADISEIPKCNCKPTDENPCGFDSECLNRMLMF
ECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDE
EECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDT
RVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTSLSSEEKGK
KTKKRTRRRRTRGEGKKESEDECFRCGDGGQLVLCDRKSCTKAYHLSCLGLGKRPFGKWE
CPWHHCDVCGRPSTSFCHFCPNSFCKEHQDGAALGSTRDGRPCCCEHDLGAVSARSAQTG
KPFPEPSKSKGKRKRRRCWRRVTEVRSRPQEW
NT seq
4059 nt
NT seq
+upstream
nt +downstream
nt
atgaagcaggcaccggagaccctcggcagcacgaacgggaagtcccagaactgtgaagtg
aatcgcgaatgttccgtgttcctcagcaaagcccagctctctaccagtctacaggagggg
gtcatgcagaagttcaacggccacgacgcacttccctttattccatccgagaagctgaag
gacctaacgtcccgtgtgtttaatggcgagcctggtgctcatgatgccagattgcgcttt
gagtcccaggaagtgaaggcgctcgggacgccgcccagcaccacccccatcaaaaacggc
tctccggagattaagctgaagatcaccaaaacgtacatgaacgggaaacctctctttgaa
tcttcgatttgtggggacagtgctgctgccgtgtcccagtcggaagaacacggacaaaaa
ccggaaaataaggccagaaggaacaggaagcggagcataaagtacgactccttgctggag
cacggtcttgttgaggcagcgctggtgtccaggatctcgagtccctccgacaaaaaggtt
gcggctaagaaagagtcctgtccaaatactggcagagacaaagaccacctgttgaaatac
agtgttggcgacttggtgtggtccaaagtgtccggttacccttggtggccgtgcatggtc
tctgctgacccactccttcacaactacaccaaacttaaaggtcagaaaaagagtgcacgc
cagtatcacgtacaattctttggtgatgccccagaaagagcttggatatttgagaagagc
cttgtagcttttgaaggagaaggacagtttgaaaaattatgccaggaaagtgccaagcag
gcacccacgaaagctgagaaaattaagctgttgaaacctatttcagggaaattgagggcc
cagtgggaaacgggcatcgttcaagcagaagaagctgcaagcatgtcggtggaggagcgg
aaggccaagttcactttcctctacgtgggggagcggcttcacctcaaccctcacgtagct
aaggaggcaggcatttctgtggaggctccgcctctgggacccatggtagagccctcagga
gtccccgaggaagctgctgctgaccccaagtccatgcgagaagagggcgttcccgtcaag
agaaggcggagagtgaagctgtctagctctgccgaaaaccgagcgggtgaccctgggaca
gtacagagtactcctcaaaagatggcagaggccgaccccaagagaggagtcgggtctcct
cctgggaggaagaaggccacggcctccgctccacgaagcaggaagggagatgcggcatcc
cagtttctggtcttctgtcagaagcacagggatgaggtggtcgcagagcacccggacgcc
tcggccgaggaggtcaaagagctgctcggctcccagtgggacatgctcaacgagaagcag
aaggcgcgctataacaccaagtttgccctcgtggcctctccccagtctgaagaagactcc
ggtaacgtaaatgggaaaaaaagaaaccataccaagaggacccaggaccctcctgaagac
gttgaaattgaagacgcacccaggaaaagactcaggaccgacaagcacggtctccggaag
agagagacggcgagtgacaagacggcccgaacaggttcttgcaaggccatggaggccgcc
acctcgctgaagagccaggcagcaacgaaacacctgtctgacgcatgcaaaccactgaag
aagcgaaatcgggcgtctgcagcagcgtcgtgcgctccttttagcaaaagttcatctcct
tctgcgtccctaactgagaatgaggtgtcggacggcccgggagacgagcccgccgagtcc
ccgtacgagagcgccgacgagacccagaccgaagcgtccgtctcctccaagaagtctgag
cggggcgtggccgccaaaaaggagtacgtgtgtcagctgtgcgagaagccgggcagcctc
ctgctgtgcgaggggccctgctgcggagccttccacctcgcctgcctcgggctggcccgg
agacccgaagggaggttcacctgcagcgagtgcgcctcagggattcactcgtgtttcgtg
tgtaaggagagcaagacggacgtcaggcgctgcgtcgtgtcgcaatgcgggaagttctac
cacgaagcctgtgtgaggaagtaccctctcaccgtgttcgagagccgaggcttccgctgc
cccctgcacagctgcgtgacctgccacgcgtccaacccttccaaccccaggccctcgaaa
gggaaaatgatgcggtgcgtccgctgccccgtcgcctaccacggaggggacgcttgtctg
gcggccggctgctccgtgatcgcttcccacagcatcatctgcacaagccatttcactgcc
cgcaaggggaagcggcatcacgcgcacgtgaacgtgagctggtgtttcgtgtgctccaaa
gggggaagcctgctgtgctgtgagtcctgcccggcggccttccaccccgactgcctgagc
atcgagatgcccgacggcagctggttctgcaacgagtgccgagccgggaagaagctgcac
ttccaggacgtcgtctgggttaaactggggaactacagatggtggccggcagaagtttgc
catcccaaaaatgttcccccaaatattcagaaaatgaagcacgagattggagaattccct
gtgtttttctttgggtctaaagattattactggacgcatcaggcgcgagtgttcccgtac
atggagggggaccggggcagccgctaccagggggtcagagggatcggaagagtcttcaaa
aacgcactgcaggaagctgaagctcgttttcgtgaaatcaaacttcaaagggaagccaga
gaaacgcaggagagtgagcgcaagcccccgccgtacaagcacattaaggtgaacaagccc
tatgggaaagtccagatccacacggccgacatctctgagatccccaagtgcaactgtaag
cccaccgacgagaacccctgcggcttcgactcggagtgtctgaaccggatgctgatgttc
gagtgccacccgcaggtgtgccccgcgggcgagtactgccagaatcagtgcttcaccaag
cgccagtaccccgagaccaagatcatcaagacggacggcaaagggtggggcctggtcgcc
aagcgggacatcagaaagggagagttcgtgaatgagtacgtcggcgagctgatcgacgag
gaggagtgcatggcgaggatcaaacacgcacatgagaacgacatcacacacttctacatg
ctcaccatagacaaggaccggataattgatgctggccccaaaggaaactattcccggttc
atgaatcacagctgccagcccaactgtgagaccctcaagtggacggtgaacggggacact
cgcgtgggcctgtttgccgtgtgcgacatccccgcagggacggagctgaccttcaactac
aacctcgactgtttgggtaacgagaagacagtctgtcggtgtggggcctccaactgcagc
gggttccttggggacagaccaaagacctcgacgtccctttcttcagaggaaaagggcaaa
aagaccaagaaaagaacgaggaggcggagaaccagaggcgaagggaagaaggagtccgag
gacgagtgtttccgctgtggggacggcggccagctggtgctgtgtgaccgcaaatcctgc
accaaggcctaccacctgtcgtgcctgggcctgggcaagcggcccttcgggaagtgggaa
tgtccttggcaccactgtgacgtgtgtggccgaccttccacgtcattctgccacttctgc
cccaactcattctgcaaggagcaccaggacggggcggccctcggctccacgcgggacggg
cggccatgctgctgcgagcatgacctgggggccgtgtcggcccggagcgcccagactggg
aaaccctttccggaacccagcaagtccaaggggaagaggaagagaaggaggtgctggcgg
agggtcacggaagtgaggagccggccccaggagtggtga
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integrated database retrieval system
