Panthera leo (lion): 122220123
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Entry
122220123 CDS
T10741
Symbol
BCKDHB
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X1
KO
K00167
2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:
1.2.4.4
]
Organism
plez Panthera leo (lion)
Pathway
plez00280
Valine, leucine and isoleucine degradation
plez00640
Propanoate metabolism
plez00785
Lipoic acid metabolism
plez01100
Metabolic pathways
plez01210
2-Oxocarboxylic acid metabolism
Module
plez_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
122220123 (BCKDHB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
122220123 (BCKDHB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
122220123 (BCKDHB)
Enzymes [BR:
plez01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
122220123 (BCKDHB)
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Motif
Pfam:
Transket_pyr
Transketolase_C
Toxin_YhaV
Motif
Other DBs
NCBI-GeneID:
122220123
NCBI-ProteinID:
XP_042795163
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Position
B2:71611160..71830773
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AA seq
392 aa
AA seq
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MAAFAATAGRLLGLRAAGTEGRLLRLRGAGLQRALLQPASATGDAAQRRQVAHFTFQPDP
EPQEYGQTQKMNLFQAITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
TIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVVPRSPFQAKGLLLSCIEDKNPCIFFEP
KILYRAAVEQVPVEPYHIPLSQAEVIQEGSDVTLVAWGTQVHVMREVASMAQEKLGVSCE
VIDLKTILPWDMDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
NT seq
1179 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgtttgcggcgactgcggggaggctgttggggctgcgtgcggctgggacagag
ggacggttgcttcggctgcgaggcgcggggctgcagcgggccttgttgcagcccgcctcg
gccactggagatgcggcacagaggcggcaggtggctcacttcactttccagcccgacccg
gagcctcaggagtatgggcaaactcagaaaatgaatcttttccaggcgataacaagtgcc
ttggataactcattggctaaagatcctacggcagtaatatttggtgaagatgttgccttt
ggtggagtctttagatgtactgttggcttgcgagacaaatatggaaaagatagagttttc
aacaccccattgtgtgaacaaggaatcgttggatttggaattgggattgcagtcactggg
gctactgccattgcggaaattcagtttgcagattacattttccctgcttttgatcagatt
gttaatgaagctgccaagtaccgctatcgctctggagatctttttaattgtggaagcctc
accatccgggccccttggggctgcgtcggccatggggctctttatcattctcagagtcct
gaagccttttttgctcactgcccaggaatcaaggtggttgtacccagaagccctttccag
gccaaaggacttcttttgtcatgcatagaggataaaaatccttgtatattttttgaacct
aaaatactttacagggcagcagttgaacaggttcctgtagaaccataccacatccccctg
tcccaggctgaagtcatacaggaagggagtgatgttactctagttgcctggggcactcag
gttcatgtcatgcgagaggtggcttccatggctcaagaaaagcttggagtgtcttgtgaa
gtcattgatctgaagaccatactaccttgggacatggatacagtttgcaagtctgtgatc
aaaacagggcgactgctaatcagtcacgaggctcccttgacaggcggctttgcatcggag
atcagctctacggttcaggaagaatgtttcctgaacctagaggctcctatatcaagagta
tgtgggtatgacacaccatttcctcacatttttgagccattctacatcccagacaaatgg
aagtgctatgatgccctccgaaaaatgatcaactattaa
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