Panthera leo (lion): 122220244 Help Entry 122220244         CDS       T10741                                  Symbol FOXO3 Name (RefSeq) forkhead box protein O3   KO K09408   forkhead box protein O3 Organism plez  Panthera leo (lion) Pathway plez01521   EGFR tyrosine kinase inhibitor resistance plez04062   Chemokine signaling pathway plez04068   FoxO signaling pathway plez04137   Mitophagy - animal plez04151   PI3K-Akt signaling pathway plez04152   AMPK signaling pathway plez04211   Longevity regulating pathway plez04213   Longevity regulating pathway - multiple species plez04218   Cellular senescence plez04722   Neurotrophin signaling pathway plez04917   Prolactin signaling pathway plez04936   Alcoholic liver disease plez05208   Chemical carcinogenesis - reactive oxygen species plez05213   Endometrial cancer plez05223   Non-small cell lung cancer Brite KEGG Orthology (KO) [BR:plez00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     122220244 (FOXO3)    04151 PI3K-Akt signaling pathway     122220244 (FOXO3)    04152 AMPK signaling pathway     122220244 (FOXO3)  09140 Cellular Processes   09141 Transport and catabolism    04137 Mitophagy - animal     122220244 (FOXO3)   09143 Cell growth and death    04218 Cellular senescence     122220244 (FOXO3)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     122220244 (FOXO3)   09152 Endocrine system    04917 Prolactin signaling pathway     122220244 (FOXO3)   09156 Nervous system    04722 Neurotrophin signaling pathway     122220244 (FOXO3)   09149 Aging    04211 Longevity regulating pathway     122220244 (FOXO3)    04213 Longevity regulating pathway - multiple species     122220244 (FOXO3)  09160 Human Diseases   09161 Cancer: overview    05208 Chemical carcinogenesis - reactive oxygen species     122220244 (FOXO3)   09162 Cancer: specific types    05213 Endometrial cancer     122220244 (FOXO3)    05223 Non-small cell lung cancer     122220244 (FOXO3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     122220244 (FOXO3)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     122220244 (FOXO3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:plez03000]     122220244 (FOXO3) Transcription factors [BR:plez03000]  Eukaryotic type   Helix-turn-helix    Fork head/winged helix other regulators     122220244 (FOXO3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  FOXO_KIX_bdg Forkhead FOXO-TAD Motif Other DBs NCBI-GeneID:  122220244 NCBI-ProteinID:  XP_042795438 UniProt:  A0A8C8WD97 LinkDB All DBs Position B2:97260711..97386632 Genome browser AA seq 672 aa AA seqDB search MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQGSPAKPSGETAADSMIPEE EDDEDDEDGSGRASSAMAIGGGGSGTLGSGLLLEDSARLLAPGGQDSGSGPALAAGALSG GTQTPLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLS QIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGG KSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSD ELDAWTDFRSRTNSNASTVSGRLSPILASTELDDVQDDDAPLSPMLYSSSASLSPSVSKP CTVELPRLTDMAGTMNLNDGLSDNLMDDLLDNITLPSSQPSPTGGLMQRSSSFPYTAKGS ALGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSH SDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQ GALGGSRALSNSVSNMGLSDSSSLGSVKHQQQSPVSQSMQTLSDSLSGSSLYSASANLPV VGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTG AKQASSQSWVPG NT seq 2019 nt NT seq  +upstreamnt  +downstreamnt atggcagaggcaccggcctccccggccccgctctctccgctcgaagtggagctggacccg gagttcgagccccagagccggccgcgctcctgtacgtggcccctgcagaggccagagctc caggggagcccggccaagccctcgggggagacggccgccgattccatgatccccgaagag gaggacgatgaagacgacgaggacggtagcggtagggccagctcggccatggcgatcggc ggcggcgggagcggcacgctgggctccgggctgctccttgaagactcggcccggctgctg gctcctggagggcaggactccgggtccgggccagccctcgcggcgggcgcgctgagcggg gggacgcagacgccgctgcagcctcagcagccactgccaccgccgcagccgggggcggct gggggctccgggcagccgaggaaatgctcgtcgcggcggaacgcctggggaaacctgtcc tacgccgacctgatcactcgcgccatcgagagctccccggacaaacggctcactctgtcc cagatctacgagtggatggtgcgctgcgtgccctacttcaaggataagggcgatagcaac agctcggccgggtggaagaactctatccggcacaacctgtcactgcacagccgtttcatg cgggtccagaatgaggggactggcaagagctcttggtggatcatcaaccctgatgggggg aagagcgggaaggcaccccggcggcgggctgtctccatggacaacagcaacaagtatacc aagagtcgtggccgtgcagccaagaagaaggcagccctgcagacagcccccgagtcagca gatgacagtccctcccagctctccaagtggcctggcagccccacgtcacgcagcagtgac gagctggatgcgtggaccgacttccgctcacgcactaattccaatgccagcacggtcagt ggccgcctgtcacccatcttggcaagcacggagttggatgacgtccaggatgatgatgca ccgctctcccccatgctctacagcagctcagctagcctgtcaccctctgtaagtaagcca tgcaccgtggagctaccacggctgaccgacatggcgggcaccatgaatctgaatgatggg ctctctgacaacctcatggatgacctgctggataacatcacactcccatcgtcccagcca tcgcccaccggagggctcatgcagcggagctctagcttcccatacaccgccaagggctcc gccctgggctctccaaccagctccttcaatagcacggtgtttggaccctcatctctgaat tccctgcgccagtctcccatgcagaccatccaagagaacaagccagctaccttctcttcc atgtcacactatggcaaccagacactccaggacctgctcacttcagactcactcagccac agcgatgtcatgatgacccagtcagaccccttgatgtctcaggccagcaccgctgtgtct gcccagaactcccgccggaacgtgatgcttcgaaatgacccaatgatgtcctttgctgcc cagcctaaccaggggagtttggtcaatcagaacttgctccaccaccagcaccaaacccag ggcgctctcggtggcagccgtgccttgtcgaattctgtcagcaacatgggcttgagcgac tccagcagccttgggtcagtcaaacaccagcaacaatctcctgtcagccagtctatgcaa accctctcggactctctctcaggctcctccttgtactcagctagtgcaaaccttcccgtc gtgggccacgagaagttccccagcgacttggacctggacatgttcaatgggagcttggag tgcgacatggagtccattatccgtagtgaactcatggatgccgatgggttggattttaat tttgattccctcatctccacacagaatgttgttggtttgaacgtggggaacttcactggt gctaagcaggcctcatctcagagctgggtgccaggctga

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