Panthera leo (lion): 122220575
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Entry
122220575 CDS
T10741
Symbol
PRKN
Name
(RefSeq) E3 ubiquitin-protein ligase parkin isoform X1
KO
K04556
parkin [EC:
2.3.2.31
]
Organism
plez Panthera leo (lion)
Pathway
plez04120
Ubiquitin mediated proteolysis
plez04137
Mitophagy - animal
plez04141
Protein processing in endoplasmic reticulum
plez05012
Parkinson disease
plez05014
Amyotrophic lateral sclerosis
plez05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
122220575 (PRKN)
04120 Ubiquitin mediated proteolysis
122220575 (PRKN)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
122220575 (PRKN)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
122220575 (PRKN)
05014 Amyotrophic lateral sclerosis
122220575 (PRKN)
05022 Pathways of neurodegeneration - multiple diseases
122220575 (PRKN)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
plez04131
]
122220575 (PRKN)
04121 Ubiquitin system [BR:
plez04121
]
122220575 (PRKN)
03029 Mitochondrial biogenesis [BR:
plez03029
]
122220575 (PRKN)
Enzymes [BR:
plez01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.31 RBR-type E3 ubiquitin transferase
122220575 (PRKN)
Membrane trafficking [BR:
plez04131
]
Autophagy
Mitophagy
PINK1-Parkin associated proteins
122220575 (PRKN)
Aggrephagy
Other aggrephagy associated proteins
122220575 (PRKN)
Xenophagy
Other xenophagy associated proteins
122220575 (PRKN)
Ubiquitin system [BR:
plez04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
RBR proteins
122220575 (PRKN)
Mitochondrial biogenesis [BR:
plez03029
]
Mitochondrial quality control factors
Mitophagy factors
Parkin-dependent mechanism factors
122220575 (PRKN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
zf-RING_14
zf-RING_12
ubiquitin
IBR_2
IBR_1
Rad60-SLD
IBR
Dsc3_N
Rad60-SLD_2
Crinkler
Motif
Other DBs
NCBI-GeneID:
122220575
NCBI-ProteinID:
XP_042796184
LinkDB
All DBs
Position
B2:complement(143969526..145308776)
Genome browser
AA seq
462 aa
AA seq
DB search
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRDDLTVQSCD
LDQQSIVHVVLRPWRKGPEREGGDGPQNALEGSRREPESLTRVDLSSSVLPAHSVGLAVI
LNNDREETLPAGRPAGRPPYNSFYVYCKGPCQRIQPGKLRVRCGTCRQATLTLAQGPSCW
DDVLIPNRMTGECQTASCPGTTAEFFFKCGAHPTADKETSVALNLITTNSRGITCITCTD
IRSPVLVFQCNHRHVICLDCFYLYCVTRLNDRQFIHDPQLGYSLPCVAGCPNSLIKELHH
FRILGEEQYNRYQQYGAEECVLQMGGVLCPHPGCGAGLLPEPGRRKVTCEGGNGLGCGFV
FCRDCKEAYHEGECSTLFEASGAVSQAYRVDEKAAEQARWEEASKETIKKTTKPCPRCHV
PVEKNGGCMHMKCPQPQCRLEWCWACSCEWNRACMGDHWFDV
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgatagtgttcgtcaggttcaactccagccatggtttcccagtggaggtcgattctgac
accagcatcttccagctcaaggaggtggttgctaagcgacagggggttccagctgaccag
ttgcgtgtgattttcgccgggaaggagcttagggatgacttgactgtgcagagctgtgac
ctggaccagcagagcatcgttcacgttgtgctgagaccctggagaaaaggcccagaaagg
gaaggaggcgacggcccacaaaacgccctggagggctcgaggagagagcccgagagcttg
acccgggtggacctcagcagctcggtcctccctgcgcactcggtgggtctggctgtgatc
ctgaataatgaccgtgaggagaccctgccagctggaaggccagcaggtagaccgccttac
aacagcttttatgtttattgcaaaggcccctgtcaaagaatacagccaggaaaactcagg
gtgcggtgtggtacctgccgacaggcgacgctcaccttggcccagggtccatcttgctgg
gacgatgtcttaatcccaaaccggatgactggtgaatgtcaaactgcaagctgtcctggg
actacagccgaatttttctttaaatgtggagcacacccaaccgctgacaaggaaacatca
gtggctttgaacctgatcacaacaaacagtcgaggcatcacctgcataacatgtaccgac
atcaggagccctgtgctggttttccagtgcaaccatcgccacgtgatttgcttagactgt
ttctacttatactgtgtgacaagacttaacgacaggcagtttatccatgaccctcagctg
ggctactctctgccgtgtgtggctggctgccccaactccttgattaaagagctccatcac
ttcaggatccttggagaagagcagtacaaccggtaccagcaatatggcgctgaagagtgt
gtgctccagatggggggcgtgctgtgccctcaccctggctgtggagcagggctgcttccc
gagccaggcaggaggaaggtcacttgtgaagggggaaatggtctgggctgcgggttcgtc
ttttgccgggactgtaaggaagcgtaccatgaaggtgaatgcagcaccctgtttgaagcc
tcaggagcagtttctcaggcctacagagttgatgagaaggccgcggaacaagctcggtgg
gaagaggcctctaaagagacaatcaagaaaaccaccaagccctgtccccgctgccatgtg
ccagttgaaaaaaatggaggatgcatgcacatgaagtgcccgcagccccagtgccgtctg
gagtggtgctgggcctgcagctgcgagtggaaccgcgcctgcatgggggaccactggttc
gacgtgtag
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integrated database retrieval system
