Panthera leo (lion): 122220593
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Entry
122220593 CDS
T10741
Symbol
RPS6KA2
Name
(RefSeq) ribosomal protein S6 kinase alpha-2 isoform X1
KO
K04373
ribosomal protein S6 kinase alpha-1/2/3/6 [EC:
2.7.11.1
]
Organism
plez Panthera leo (lion)
Pathway
plez04010
MAPK signaling pathway
plez04114
Oocyte meiosis
plez04150
mTOR signaling pathway
plez04714
Thermogenesis
plez04720
Long-term potentiation
plez04722
Neurotrophin signaling pathway
plez04914
Progesterone-mediated oocyte maturation
plez04931
Insulin resistance
plez05135
Yersinia infection
plez05207
Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122220593 (RPS6KA2)
04150 mTOR signaling pathway
122220593 (RPS6KA2)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
122220593 (RPS6KA2)
09150 Organismal Systems
09152 Endocrine system
04914 Progesterone-mediated oocyte maturation
122220593 (RPS6KA2)
09156 Nervous system
04720 Long-term potentiation
122220593 (RPS6KA2)
04722 Neurotrophin signaling pathway
122220593 (RPS6KA2)
09159 Environmental adaptation
04714 Thermogenesis
122220593 (RPS6KA2)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
122220593 (RPS6KA2)
09171 Infectious disease: bacterial
05135 Yersinia infection
122220593 (RPS6KA2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
122220593 (RPS6KA2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122220593 (RPS6KA2)
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
plez03019
]
122220593 (RPS6KA2)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
122220593 (RPS6KA2)
Protein kinases [BR:
plez01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
122220593 (RPS6KA2)
Messenger RNA biogenesis [BR:
plez03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Stress granule specific factors
122220593 (RPS6KA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Kdo
Pkinase_fungal
Pkinase_C
Motif
Other DBs
NCBI-GeneID:
122220593
NCBI-ProteinID:
XP_042796211
LinkDB
All DBs
Position
B2:complement(148437155..148790719)
Genome browser
AA seq
758 aa
AA seq
DB search
MPIAQLLELWKKIEVEPMEIETPEEDLNLDSEPIVQDTVEEGKCDSALPGTKSAASLEEE
GTVKEIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKTKGSDTGQLYAMKVLKK
ATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFSRLSKEVM
FTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKR
AYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAK
LGMPQFLSTEAQSLLRALFKRNPCNRLGAGLDGVEEIKRNPFFMTVDWNKLYRKEIKPPF
KPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLVQEASPQDLHKA
TVHPIVQQLHGNNVHFTDGYEIKEDIGVGSYSVCKRCVHKATEAEYAVKIIDKSKRDPSE
EIEILLRYGQHPNIITLKDVYDDGKFVYLVTELMRGGELLDRILRQRHFSEREASDVLCI
ITRTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCYTA
NFVAPEVLKRQGYDAACDIWSLGTLLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSG
GNWDSVSDAAKDVVSKMLHVDPHQRLTAVQVLKHPWIVNREYLSQNQLSRQDAHLVKGAM
AATYFALNRTPQAPRLEPVLSSSLAQRRGMKRLTSTRL
NT seq
2277 nt
NT seq
+upstream
nt +downstream
nt
atgccgatcgcacagttgctggaactatggaagaagatcgaggtggagcccatggaaatc
gagacccccgaggaggatcttaacctggactcggagcccatcgtacaagataccgtggaa
gaaggcaaatgtgactccgccttgcctgggaccaagtcggccgcgtcactagaggaggaa
ggcaccgtgaaggagatcgacatcagccaccatgtgaaggaagggtttgaaaaggccgac
ccttcccagtttgaactgctgaaagtcttaggacaaggatcctacggaaaggtgttcctg
gtgaggaagaccaaggggtctgacacgggacagctgtacgcgatgaaagtcctcaagaaa
gctactttgaaagttcgggaccgagtccgatcgaagatggaaagagacattttggcagaa
gtgaatcaccctttcatcgtaaagcttcattatgcctttcagacggaggggaagctctac
ctgatactggacttcctgcgaggaggggacctcttcagccggctctccaaagaggtgatg
ttcactgaggaggatgtcaagttctacctggctgagctggccttggcgttagaccacctg
cacggcctggggatcatctacagggacctgaagcccgagaacatcctgctggacgaagag
ggacacattaagatcacagatttcgggttgagtaaggaggccatcgaccacgataagaga
gcttactccttctgcgggaccatagagtacatggcacccgaggtggtgaaccggcgggga
cacacgcagagcgccgactggtggtccttcggtgtgctcatgttcgagatgctcacagga
tcgctgccgttccaggggaaggacaggaaggagaccatggccctcatcctcaaagccaag
ctgggcatgccacagttcctcagcaccgaagcccagagcctgctgagagccctcttcaaa
cggaacccgtgcaaccgtctgggtgctggcctcgacggggtagaggagatcaagcggaac
cccttcttcatgaccgtagactggaataagctgtaccggaaggagatcaagccaccgttc
aagccagcggtgggcaggcccgaggacaccttccactttgaccccgagttcacagcacgg
acgcccacagactcacctggcgtcccccccagcgccaacgctcatcatctgttcagagga
ttcagtttcgtggcctcgagtctggtccaggaggcctccccgcaagatctgcacaaagcc
acggtccaccccatcgtgcagcagttacacgggaacaacgtacacttcactgacggctac
gagatcaaggaggacatcggggtgggctcctactccgtgtgcaagcgatgcgtgcataaa
gcgacggaggcagagtacgccgtgaagatcatcgataagagtaaaagagacccctcggaa
gagatcgagatcctcctgagatacggacagcatccgaacatcatcacgctcaaagacgtc
tacgacgacggcaagttcgtgtacctggtgacggagctgatgcgtggcggggagctcctg
gaccgcatcctgcgacagcgacacttctcggagcgggaggccagcgacgtgctgtgcatc
atcaccaggaccatggattacctccactcgcagggggttgttcatcgagacctgaagcca
agtaacatactgtacatggacgagtccggaaaccctgagtccatccgcatctgcgatttc
gggttcgccaagcagcttcgagctgagaacgggctgttgatgacaccctgctacacggca
aactttgtcgccccggaggtcctgaagcgacaaggctatgacgcagcgtgtgacatctgg
agtctggggaccctgctttacaccatgctggcaggatttaccccttttgcaaacggcccc
gatgacactcccgaggagattttggcgaggatcggcagtgggaaatacgccctttctggg
gggaactgggactccgtctctgatgcggcaaaggatgtcgtatccaagatgctccacgtg
gacccccatcagcgcctgacggcagttcaagttctcaaacacccatggatcgtgaacaga
gagtacctgtcccaaaaccagctcagcagacaggacgcccacctggtgaagggggctatg
gccgccacctactttgccctgaaccgaaccccgcaggcgccgcggctggagcccgtgctg
tcgtccagcctggcgcagcgcaggggcatgaagagactcacgtccacgaggctgtag
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