Panthera leo (lion): 122220605 Help Entry 122220605         CDS       T10741                                  Symbol AFDN Name (RefSeq) afadin isoform X1   KO K05702   afadin Organism plez  Panthera leo (lion) Pathway plez04014   Ras signaling pathway plez04015   Rap1 signaling pathway plez04024   cAMP signaling pathway plez04517   IgSF CAM signaling plez04520   Adherens junction plez04530   Tight junction plez04670   Leukocyte transendothelial migration Brite KEGG Orthology (KO) [BR:plez00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     122220605 (AFDN)    04015 Rap1 signaling pathway     122220605 (AFDN)    04024 cAMP signaling pathway     122220605 (AFDN)   09133 Signaling molecules and interaction    04517 IgSF CAM signaling     122220605 (AFDN)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     122220605 (AFDN)    04530 Tight junction     122220605 (AFDN)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     122220605 (AFDN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RA DIL PDZ FHA PDZ_6 RA_3 RA_2 PDZ_2 RASSF8-10_RA Yop-YscD_cpl Motif Other DBs NCBI-GeneID:  122220605 NCBI-ProteinID:  XP_042796234 LinkDB All DBs Position B2:149365379..149503982 Genome browser AA seq 1799 aa AA seqDB search MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGEERRLDIDEKPLVVQLNWNK DDREGRFVLKNENDALPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEAVRQ ASEKDDRPFQGDDLENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLERRMQEFRS SDGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIAR VMLPPGAQHSDENGAKETILDDDECPLQIFREWPTDRGVLVFQLKRRPPDYVPKKTKKHV DGKLVKGKERAEGSGYGSALPPEKLPYLVELSPDGSDSRDKPKLYRLQLSVTEVGTEKFE ENSIQLFGSGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETTMLQSGMKVQFGAS HVFKFVDPSQDHAVAKRPVDGGLTAKGPRQKPGIVQETTFDLGGDVHSGAALPASKSATR LDSDRAPPAPGTAERGTVKPMLRLEQQDCRRQENRTQDALGPELILPASIEFRESSEDSF LSAIINYTNSSTVHFKLSPTYVLYMACRYVLSSQYRPDVSPTERTHKVIAIVNKMVSMME GVIQEVDQVDQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAHLVQMAFK YLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMALLRRCRVNAALTIQLFS QLFHFINMWLFNRLVTDPESGLCSHYWGAIIRQQLGHVEAWAEKQGLELAADCHLSRIVQ ATTLLTMDKYAPEDTPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIESVVAVAEN TADELARSDGREVQLQEDPDLQLPFLLPEDGYSCDVVRNVPNGLQEFLDPLCQRGFCRLI PHARSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGA GQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLE VAKQGAIYHGLATLLNQPSPMMQRVSDRRGSGKPRPKSEGFELYNNSAQNGSPESPQLPW AEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYAPGAAAKITSVSTGNLCTE EQTPPPRPEAYPIPTQTYTREYFTFPASRSQDRVAPPQNQWPNYEEKPHVHADGHQSGPA MQRVTRSQEELREDKAYQLERHRLEAVLDRKSDSDVWIQPSSSVGSSTSSQEHLDPCSKS GTPASTLTKSGPGRWKTPASAQPLPAAPPPAQTDLPPPPPPPPAHYAGDFDGVPVDLPLP PPPSGQAAAERRKREEQQRWYEKEKARLEEERDRKRREQERKLGQMRSQALNPAAFSPVT VAHAKPEKPSTLQRPQDTVIRELQPQQQPRTIERRDLQYITVSREELSSGDSLSPDPWKR DAREKLEKQQQMHIVDMLSREIRELQSKPERSAEDSDRLRKLMLEWQFQKRLQESQQKDE DDEEEEDDDVDTMLIMQRLEAERRARLQDEERRRQRQLDDMRRREAEDRARQEEERTKRD AEDKRRQEEGYYSRLEAERRRQHAEAERRLLEPEEPGLGRPPLPRGYELPAPSSPAAAPP PPPQRTASSLQAPALSPDSLYTARLVAYHEEEEEEDCSLAGPNSSVGSSGAVIGARDGSR DPRERLAKSHDADLPGNSGAPENLTFKERQRLFSQGQDVSNKVKASRKLTELENELNTK NT seq 5400 nt NT seq  +upstreamnt  +downstreamnt atgtcggcgggcggccgcgacgaggagcggcggaagctggccgacatcatccaccactgg aacgccaaccggctggacctgttcgagatcagccagcccaccgaggatttggagtttcat ggcgtaatgagattttattttcaagataaagctgctggaaacttcgcaacaaaatgcatt cgggtctctagtacggccaccacgcaagacgtgatcgagacgctggcagagaaattccgc cctgacatgcggatgctgtcgtccccaaagtactccctctacgaagttcacgtcagcgga gaagaaagaagattggatatagatgagaaaccccttgttgtgcagttgaattggaataaa gatgaccgagagggcagattcgttcttaagaacgagaacgatgcccttcctcctaagaag gctcaaagcaacggacctgaaaagcaggagaaagaaggtgttatccagaacttcaagaga actctctccaagaaagagaagaaagagaaaaagaagagagagaaagaggcagtgaggcag gcatctgagaaagatgatcggcctttccaaggggatgacctcgagaattcccgactggcc gccgaggtttacaaagacatgcccgagaccagcttcacgcgcacgatctccaaccccgag gtggtcatgaagcgccggcggcagcagaagctggagaggcggatgcaggagttccggagc tcggacggacggccggactcaggtggaacactgagaatttatgcagatagcttaaaaccg aacattccctacaagacaatcctgctgtccaccacggatcctgctgactttgctgtggcc gaggctctagagaaatacggtctggagaaggagaaccctaaagattactgcatcgcccgg gttatgctgcctcctggagcccagcattcggatgaaaacggtgctaaagaaacgatcctc gacgatgacgagtgtcctttgcagatcttcagggagtggccaactgaccgaggggtttta gtctttcagttgaagaggaggccgccagactacgtcccgaagaaaacgaagaaacatgtc gacgggaagctggtgaaagggaaagagagagccgagggttccggctacggctcagcactt ccgcccgagaagttgccctacctggtggagctcagcccagatggttctgactccagggac aagcccaagctttaccgccttcagttgagcgtcactgaggtcgggacagagaagttcgag gagaactccatccagctgtttggatcaggaattcagccccatcactgtgacctcacaaac atggatggagttgtcaccgtgactccgagaagcatggacgccgagacgtacgtggaagga cagcgcatctccgagacgaccatgctgcagagcgggatgaaagtgcagtttggggcgtca cacgtgttcaagtttgtggaccccagccaggaccacgctgtggccaagagacccgtggat ggaggcctgacggccaagggccccagacagaagcctggaattgttcaggagacaactttc gatttggggggagatgttcacagcggggcagcgctgccagcgagcaagagcgccaccagg ctggacagcgacagggcaccgcctgcccccggcacggccgagcgcgggacagtgaagccg atgctgagactggagcagcaggactgccgccggcaagaaaacagaactcaggatgctctt gggcctgaactcatactgcctgcaagcattgaattcagggaaagttctgaagattcattt ttatctgccattataaattatactaatagctctacagtccattttaagttgtcacctaca tatgtattatatatggcatgtcggtatgtattgtcgagccagtacagacccgatgtcagt cctacagagcgtactcacaaagtgattgccatagtcaacaagatggtgagcatgatggag ggggtgattcaggaagtagaccaggttgatcagaaacagaagaatatcgcaggggcgctt gctttctggatggccaacgcatctgagcttctcaacttcattaagcaggaccgagatctt agtcgaatcacattggacgcccaagatgttttagcacacttggttcaaatggcgtttaaa tatctggttcattgtcttcagtcagaactgaataactacatgccggcttttctggatgac cctgaagagaacagtctacaaagaccaaaaatagatgacgtcttgcacacgctcacggga gcgatggcgctgctgaggcgctgcagggtcaatgctgctctgaccatccagcttttctct cagctcttccacttcatcaacatgtggctcttcaacagattggtgaccgaccccgagtcg ggactgtgctctcactattggggggcgatcatccgccagcagctggggcacgtggaagcc tgggcagagaagcagggattagagctggcggccgactgtcacctgagccggatagtgcag gcgaccactttgctcaccatggataaatatgctcctgaggacaccccaaatatcaacagc acctgctttaagttaaattcactgcagctgcaggccttgctacagaattaccactgtgcg cccgatgagccctttatccccacggacctgatagagagcgtcgtggccgtggccgaaaac acggccgacgagctggcgcgcagcgatgggcgggaggtgcagctgcaagaggaccctgat ctgcagctgccttttcttctgccggaagacggctattcttgtgacgtcgtcaggaacgtt ccaaacggtttacaagaatttctggaccctctgtgccagagagggttttgcaggttaatt cctcatgcacgttcaccaggtacttggacgatctattttgaaggtgcagattatgagagc catcttctgcgtgagaacacagagctggctcagcctctgcggaaagaacctgaaataatc actgtgactctcaaaaagcaaaacggaatgggcctcagcattgtcgcggcaaagggtgct ggtcaagataaacttggaatctatgtcaagtctgtcgtaaaaggaggtgctgcagatgtg gacggacgcctggccgcaggtgaccagctgctcagtgtggatggacgaagtctggtagga ctctctcaagaaagggcagcagaactcatgacaaggaccagttccgtggtgacactggaa gtagccaagcaaggagcgatctaccacggcctggccaccctgctcaatcagccatccccg atgatgcagagagtttcagaccgtcgtggctcaggtaaaccccgaccaaagagtgaaggt ttcgagctctataacaattcagctcaaaacgggtcacccgagagccctcagctgccttgg gcagaatacagcgaaccgaagaagctccctggcgatgacaggctgatgaagaaccgggct gaccaccgctccagccccaacgtggcaaatcagccccccagtcccggagggaaaagcgcg tacgcccctggagcagccgcgaagatcacgtccgtctccaccggaaacctctgcactgag gagcagacccctccacctcgacctgaggcctaccccatccccacccagacgtacaccagg gagtacttcaccttcccggcctccaggtcccaggaccgcgtggctccccctcagaaccag tggcccaattacgaggagaagccgcacgtgcacgcagatggtcatcagtccggccccgcg atgcagcgcgtcacccgctcccaggaggaacttcgggaggataaagcttaccaactcgag cggcatcggctggaggcggtgctggatcgcaagtccgacagcgacgtgtggatccagccg agctcctcggtgggctccagcacgtccagccaggagcacctggacccctgctccaagtcg ggcacccccgcctccacgctgaccaagagcggccccgggcgctggaagacgccggcctcc gcgcagcccctgccggcggcccccccgcccgcgcagacagacctgcccccgccaccccca ccgcctcccgcgcactacgccggagacttcgacggggtccccgtggacctgcccctccca ccccctcccagcggccaggcggcggcggagcggaggaaacgggaggagcagcagcgctgg tacgagaaggagaaggcccgcctggaggaggagcgggacaggaagcgccgggagcaggag cggaagctgggccagatgcgctcccaggccctgaacccggccgcgttctccccggtgacc gtcgcgcacgcgaagccggagaaaccttccacgctccagaggccccaggacacggtcatc cgggagctgcagccccagcagcagccacgcaccatcgagcgccgagacttgcagtacatc acggtcagcagagaggagctgtcctcgggggacagcctgtcccccgacccctggaagcgg gacgccagggagaagctggagaagcagcagcagatgcacatcgtggacatgctgagcagg gagatccgggagctccagagcaagcccgagcgcagcgccgaggacagcgaccgcctgcgc aagctcatgctggagtggcagttccagaagagactgcaggagtcccagcagaaggacgag gacgacgaggaggaggaggacgacgacgtggacaccatgctgatcatgcagcgcctcgag gctgagcggagagcaaggttacaggacgaggagcggcggcggcagcggcagctggacgac atgcgcaggcgggaagcggaggaccgcgccaggcaggaggaggagaggacgaagcgagac gccgaagacaagaggcgacaggaagaaggttattacagccgcctggaagccgagaggcgc agacagcacgcggaggccgagcgcaggctgctggagccggaggagccgggcctgggcaga ccgccgctgccgcggggctacgagctcccggccccgtcctccccggcggctgctcctcct cccccgcctcagcggaccgcctcctccctgcaggccccggccctgtccccagactccctg tacaccgccaggctcgttgcgtaccacgaggaggaggaggaggaggactgcagtctggca ggaccaaactcttccgtgggatcttccggggcagtgatcggtgcccgtgacggctcccgg gacccgagagagaggctggcgaaaagccatgatgcagatttacctggaaattccggagcc cctgagaacttgacattcaaagagcgccagcggctgttctcacaaggtcaagatgtgtcc aataaagtgaaagcctctcgtaaattaacagaactggaaaacgaactgaacacaaagtga

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